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Atlas of Human Poisoning and Envenoming, Second Edition PDF

888 Pages·2014·50.258 MB·English
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TOXICOLOGY Diaz Second Edition Atlas of HUMAN POISONING and ENVENOMING Second Edition Clinicians undergoing competency testing, certification, and pe- riodic recertification are frequently faced with computer-based H exams designed to evaluate clinical acumen and judgment. Test a questions often include an image or radiograph followed by a U n vignette of the clinical encounter and a series of questions. Designed to better prepare practitioners for image-intense, d M computer-based examinations in their respective fields, Atlas of Human Poisoning and Envenoming is a visual and written re- Atlas of EA minder of the ubiquitous sources of toxins and toxoids in the en- vironment and the outcomes of accidental or intentional toxic N N exposures in humans. A HHHHUUUUMMMMAAAANNNN V The Second Edition has been restructured with bulleted text, tables, P t and figures resembling the vignettes that accompany national ex- l E a aminations. Combining the four specialties of toxicology—analyti- O cal, medical, environmental, and industrial—into one comprehen- N s sive atlas, the book presents photographs and diagrams of toxic PPPPOOOOIIIISSSSOOOONNNNIIIINNNNGGGG plants and animals, their mechanisms of poisoning or envenoming, I o aaaannnndddd OS and the human responses caused by toxic exposure. f O Highlights of the new edition include M N EEEENNNNVVVVEEEENNNNOOOOMMMMIIIINNNNGGGG • Prescription and illicit drug abuse epidemics I • Environmental and occupational nephrotoxicology and neurotoxicology N I • Tick paralysis N G • Petrochemical toxicants G • Biological, chemical, and radiological warfare agents • Workplace substance abuse screening and monitoring • Epidemiological design and statistical analysis of toxicological investigations The book is conveniently divided into four sections covering general medical toxicology, environmental toxicology, industrial and occupational toxicology, and epidemiology and statistics for toxicology. Supplemented with a 16-page color insert, the second edition includes new images and tables. The atlas will be a useful study guide for a range of practitioners preparing for a lifetime of image-intense national examinations. Second K14564 Edition JJJaaammmeeesss HHH... DDDiiiaaazzz 6000 Broken Sound Parkway, NW Suite 300, Boca Raton, FL 33487 711 Third Avenue New York, NY 10017 an informa business 2 Park Square, Milton Park www.crcpress.com Abingdon, Oxon OX14 4RN, UK w w w . c r c p r e s s . c o m Second Edition Atlas of HUMAN POISONING and ENVENOMING Second Edition Atlas of HUMAN POISONING and ENVENOMING James H. Diaz LSUHSC School of Public Health New Orleans, Louisiana, USA Boca Raton London New York CRC Press is an imprint of the Taylor & Francis Group, an informa business CRC Press Taylor & Francis Group 6000 Broken Sound Parkway NW, Suite 300 Boca Raton, FL 33487-2742 © 2015 by Taylor & Francis Group, LLC CRC Press is an imprint of Taylor & Francis Group, an Informa business No claim to original U.S. Government works Version Date: 20140903 International Standard Book Number-13: 978-1-4665-0541-4 (eBook - PDF) This book contains information obtained from authentic and highly regarded sources. While all reasonable efforts have been made to publish reliable data and information, neither the author[s] nor the publisher can accept any legal responsibility or liability for any errors or omissions that may be made. The publishers wish to make clear that any views or opinions expressed in this book by individual editors, authors or contributors are personal to them and do not necessarily reflect the views/opinions of the publishers. The information or guidance contained in this book is intended for use by medical, scientific or health-care professionals and is provided strictly as a supplement to the medical or other professional’s own judgement, their knowledge of the patient’s medical history, relevant manufacturer’s instructions and the appropriate best practice guidelines. Because of the rapid advances in medical science, any information or advice on dosages, procedures or diagnoses should be independently veri- fied. The reader is strongly urged to consult the relevant national drug formulary and the drug companies’ printed instructions, and their websites, before administering any of the drugs recommended in this book. This book does not indicate whether a particular treatment is appropriate or suitable for a particular individual. Ultimately it is the sole responsibility of the medical professional to make his or her own professional judgements, so as to advise and treat patients appropriately. The authors and publishers have also attempted to trace the copyright holders of all material reproduced in this publication and apologize to copyright holders if permission to publish in this form has not been obtained. If any copyright material has not been acknowl- edged please write and let us know so we may rectify in any future reprint. Except as permitted under U.S. Copyright Law, no part of this book may be reprinted, reproduced, transmitted, or utilized in any form by any electronic, mechanical, or other means, now known or hereafter invented, including photocopying, microfilming, and recording, or in any information storage or retrieval system, without written permission from the publishers. For permission to photocopy or use material electronically from this work, please access www.copyright.com (http://www.copy- right.com/) or contact the Copyright Clearance Center, Inc. (CCC), 222 Rosewood Drive, Danvers, MA 01923, 978-750-8400. CCC is a not-for-profit organization that provides licenses and registration for a variety of users. For organizations that have been granted a photocopy license by the CCC, a separate system of payment has been arranged. Trademark Notice: Product or corporate names may be trademarks or registered trademarks, and are used only for identifica- tion and explanation without intent to infringe. Visit the Taylor & Francis Web site at http://www.taylorandfrancis.com and the CRC Press Web site at http://www.crcpress.com Contents Preface . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . ix Acknowledgments . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . xi Author . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . xiii Section i General Medical toxicology Chapter 1 The Pharmacology of Human Poisoning and Envenoming . . . . . . . . . . . . . . . . . . 3 Chapter 2 General Poisoning Management . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .21 Chapter 3 Diagnostic Work-Up of the Poisoned Patient . . . . . . . . . . . . . . . . . . . . . . . . . . . . 37 Chapter 4 Poison Antidotes . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .53 Chapter 5 Toxicity of Antiseptics and Drug Additives . . . . . . . . . . . . . . . . . . . . . . . . . . . . .81 Chapter 6 Poisonings with Over-the-Counter and Opioid Analgesics . . . . . . . . . . . . . . . . . 89 Chapter 7 Household Product Poisonings . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .105 Chapter 8 Drug and Illicit Substance Abuse . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 167 Chapter 9 Anticonvulsants and Sedative-Hypnotics . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 207 v vi Atlas of Human Poisoning and Envenoming Chapter 10 Reproductive and Perinatal Toxicology and Teratogenesis . . . . . . . . . . . . . . . 217 Chapter 11 Hypoglycemic and Other Endocrine Agent Toxicity . . . . . . . . . . . . . . . . . . . . 233 Chapter 12 Cardiovascular Drug Toxicity . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 241 Chapter 13 Antibiotic Toxicity . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 257 Chapter 14 Anticancer Drug Toxicity . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 269 Chapter 15 Environmental and Occupational Nephrotoxicology . . . . . . . . . . . . . . . . . . . .281 Chapter 16 Neurotoxicology . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 309 Section ii environmental toxicology Chapter 17 Food Poisoning . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .359 Chapter 18 Seafood Poisoning . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 379 Chapter 19 Mushroom Poisonings . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 395 Chapter 20 Herbal Poisonings . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 413 Chapter 21 Common Poisonous Household and Garden Plants . . . . . . . . . . . . . . . . . . . . . 443 Chapter 22 Bites and Stings: Terrestrial Envenomings . . . . . . . . . . . . . . . . . . . . . . . . . . . .477 Chapter 23 Common Arthropod Vectors of Infectious Diseases . . . . . . . . . . . . . . . . . . . .525 Chapter 24 Tick Paralysis . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 557 Contents vii Chapter 25 Bites and Stings: Marine Envenomings . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 569 Chapter 26 Voodoo, Hoodoo, and Cajun Traditions and Poisonings . . . . . . . . . . . . . . . . . 583 Section iii industrial and occupational toxicology Chapter 27 Volatile Organic Chemicals . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 613 Chapter 28 Petrochemical Toxicity . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .629 Chapter 29 Industrial Gas Exposures and Occupational Lung Diseases . . . . . . . . . . . . . . 645 Chapter 30 Metal and Metalloid Poisonings . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .673 Chapter 31 Pesticide Poisonings: Insecticides, Rodenticides, and Herbicides . . . . . . . . . . 707 Chapter 32 Radiation Toxicology . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 727 Chapter 33 Chemical, Biological, and Radiological Weapons and Warfare . . . . . . . . . . . . 747 Chapter 34 Workplace Substance Abuse Monitoring . . . . . . . . . . . . . . . . . . . . . . . . . . . . .769 Chapter 35 Miscellaneous Toxicants . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 813 Section iV epidemiology and Statistics for toxicology Chapter 36 Epidemiology and Statistics for Toxicology . . . . . . . . . . . . . . . . . . . . . . . . . . .843

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