springer proceedings in physics 114 springer proceedings in physics 92 BeyondtheStandardModel2003 104 ComplexComputing-Networks Editor:H.V.Klapdor-Kleingrothaus Brain-likeandWave-oriented ElectrodynamicAlgorithms 93 ISSMGE Editors:I.C.GöknarandL.Sevgi ExperimentalStudies Editor:T.Schanz 105 ComputerSimulationStudies 94 ISSMGE inCondensed-MatterPhysicsXVIII NumericalandTheoreticalApproaches Editors:D.P.Landau,S.P.Lewis, Editor:T.Schanz andH.-B.Schüttler 95 ComputerSimulationStudies inCondensed-MatterPhysicsXVI 106 ModernTrendsinGeomechanics Editors:D.P.Landau,S.P.Lewis, Editors:W.WuandH.S.Yu andH.-B.Schüttler 107 MicroscopyofSemiconductingMaterials 96 ElectromagneticsinaComplexWorld Proceedingsofthe14thConference, Editors:I.M.Pinto,V.Galdi, April11–14,2005,Oxford,UK andL.B.Felsen Editors:A.G.CullisandJ.L.Hutchison 97 Fields,Networks, ComputationalMethodsandSystems 108 HadronColliderPhysics2005 inModernElectrodynamics ProceedingsoftheiTiConferenceinTur- ATributetoLeopoldB.Felsen bulence2005 Editors:P.RusserandM.Mongiardo Editors: M. Oberlack, S. Guenther, T. Weller,G.Khujadze,A.Osman,M.Frewer, 98 ParticlePhysicsandtheUniverse J.Peinke Proceedingsofthe9thAdriaticMeeting, Sept.2003,Dubrovnik 109 ProgressinTurbulence2 Editors:J.Trampetic´andJ.Wess Proceedingsofthe14thConference, 99 CosmicExplosions April11–14,2005,Oxford,UK Onthe10thAnniversaryofSN1993J Editors:A.G.CullisandJ.L.Hutchison (IAUColloquium192) Editors:J.M.MarcaideandK.W.Weiler 110 Titel:NonequilibriumCarrierDynamics inSemiconductors 100 LasersintheConservationofArtworks Untertitel: Proceedings of the 14th In- LACONAVProceedings, ternational Conference, July 25-29, 2005, Osnabrück,Germany,Sept.15–18,2003 Chicago,USA Editors:K.Dickmann,C.Fotakis, Editors:M.Saraniti,U.Ravaioli andJ.F.Asmus 101 ProgressinTurbulence 111 VibrationProblemsICOVP2005 Editors:J.Peinke,A.Kittel,S.Barth, Editors:E.Inan,A.Kiris andM.Oberlack 102 AdaptiveOptics 112 ExperimentalUnsaturatedSoil forIndustryandMedicine Mechanics Proceedings Editor:T.Schanz ofthe4thInternationalWorkshop Editor:U.Wittrock 113 Theoretical and Numerical Unsaturated SoilMechanics 103 ComputerSimulationStudies Editor:T.Schanz inCondensed-MatterPhysicsXVII Editors:D.P.Landau,S.P.Lewis, 114 AdvancesinMedicalEngineering andH.-B.Schüttler Editors:T.M.Buzug Volumes67–91arelistedattheendofthebook. Thorsten M. Buzug (Ed.) Advances in Medical Engineering With296Figures 123 ProfessorDr.ThorstenM.Buzug InstituteofMedicalEngineering UniversityofLuebeck RatzeburgerAllee160 D-23538Luebeck,Germany [email protected] ProfessorDr.DietrichHolz ProfessorDr.JensBongartz ProfessorDr.MatthiasKohl-Bareis ProfessorDr.UlrichHartmann DepartmentofMathematicsandTechnology RheinAhrCampusRemagen,Germany Dr.SimoneWeber CentralInstituteforElectronics ResearchCentreJuelich,Germany LibraryofCongressControlNumber:2007920044 ISSN 0930-8989 ISBN 978-3-540-68763-4SpringerBerlinHeidelbergNewYork Thisworkissubjecttocopyright.Allrightsarereserved,whetherthewholeorpartofthematerialisconcerned, specificallytherightsoftranslation,reprinting,reuseofillustrations,recitation,broadcasting,reproduction onmicrofilmorinanyotherway,andstorageindatabanks.Duplicationofthispublicationorpartsthereofis permittedonlyundertheprovisionsoftheGermanCopyrightLawofSeptember9,1965,initscurrentversion, andpermissionforusemustalwaysbeobtainedfromSpringer-Verlag.Violationsareliabletoprosecution undertheGermanCopyrightLaw. SpringerisapartofSpringerScience+BusinessMedia. springer.com ©Springer-VerlagBerlinHeidelberg2007 Theuseofgeneraldescriptivenames,registerednames,trademarks,etc.inthispublicationdoesnotimply, evenintheabsenceofaspecificstatement,thatsuchnamesareexemptfromtherelevantprotectivelawsand regulationsandthereforefreeforgeneraluse. Typesetting:Digitaldatasuppliedbyeditor Production:LE-TEXJelonek,Schmidt&VöcklerGbR,Leipzig Coverconcept:FridoSteinen-Broo,eStudioCalamarS.L.,Spain Printedonacid-freepaper SPIN:11546115 7/3100/YL 543210 Preface Continuous improvements in medical imaging together with advanced image processing algorithms, biomechanical simulations and interventional monitoring strategies lead to significant progress in computer-aided diagnosis, treatment planning and therapy. Navigation in image-guided surgery provides significant advantages in accuracy due to today’s sophisticated techniques of patient-data visualization in combination with the flexibility and precision of novel surgical tools like robots and laser scalpels. These tools give finer control over sensitive movements in diseased anatomical areas and therefore, allow more surgical procedures to be performed using minimally invasive techniques than ever before. After successful launch in the years 2002 and 2004 the Third Physics Days Remagen (3rd RPT – Remagener Physiktage) together with the Second Scientific Workshop of Medical Robotics, Navigation and Visualization (2nd MRNV) is again a forum of current research and development trends in the fields of physics, engineering, mathematics and computer sciences in biomedical engineering. RheinAhrCampus Remagen, Research Centre Jülich and the University of Lübeck provide a platform for scientists from industry, clinics, universities and research labs to present the recent results of their projects. Additionally, we have encouraged students to present their diploma-, master- and PhD-projects. Foci of the 2007 RPT – MRNV conference are medical imaging (CT, MRT, US, PET, SPECT etc.), medical image processing (segmentation, registration, visualization etc.), computer-assisted surgery (medical robotics, navigation – MRNV workshop), biomechanics (motion analysis, accident research, computer in sports, ergonomics etc.), biomedical optics (OCT, soft-tissue optics, optical monitoring etc.) and laser medicine (tissue ablation, gas analytics, topometry etc.). Additionally, clinical application studies and other interesting fields of biomedical engineering have been included as well. As chair of the Third Physics Days Remagen (Remagener Physiktage – RPT 2007) and the Second Scientific Workshop of Medical Robotics, Navigation and Visualization (MRNV 2007) and on behalf of Karl Ziemons, Research Centre Jülich, and Dietrich Holz, RheinAhrCampus Remagen, I would like to thank the members of the program committee for the selection of works included in these proceedings. VI Advances in Medical Engineering The members of the RPT – MRNV 2007 program committee are: Til Aach RWTH Aachen Jens Bongartz RheinAhrCampus Remagen Thorsten M. Buzug University of Lübeck Hartmut Dickhaus FH Heilbronn/University of Heidelberg Olaf Dössel University of Karlsruhe Jürgen Eichler TFH Berlin Rolf Ellegast BGIA, Berufsgenossenschaft St. Augustin Werner Falkenstein StarMedTech GmbH Karin Gruber University of Koblenz Heinz Handels UKE University of Hamburg Ulrich Hartmann RheinAhrCampus Remagen Stefan Haßfeld University of Heidelberg Wolfram Hell University of Munich Peter Hering University of Düsseldorf Gerd Hirzinger DLR Oberpfaffenhofen Dietrich Holz RheinAhrCampus Remagen Alwin Kienle University of Ulm Edmund Koch TU Dresden Matthias Kohl-Bareis RheinAhrCampus Remagen Steffen Leonhardt Helmholtz Institute RWTH Aachen Tim C. Lueth Humboldt University of Berlin Heinz-Otto Peitgen University of Bremen, MeVis Bremen Siegfried J. Pöppl University of Lübeck Robert Sader University of Frankfurt Georg Schmitz RheinAhrCampus Remagen Klaus-Peter Schmitz University of Rostock Herbert Schneckenburger Hochschule Aalen Jens Steinbrink Charité, HU Berlin Achim Schweikard University of Lübeck Gudrun Wagenknecht Research Centre Jülich Simone Weber Research Centre Jülich Thomas Wittenberg Fraunhofer Institute IIS Erlangen Heinz Wörn University of Karlsruhe Waldemar Zylka University of Applied Science Gelsenkirchen Preface VII Additionally, I would like to thank the following colleagues for accepting our key talk invitations: Dr. Jörn Borgert (Philips Research Europe - Hamburg) Magnetic Particle Imaging Prof. Dr. Wolfgang Demtröder (University of Kaiserslautern) Laser Spectroscopy in Biology, Medicine und Environmental Sciences Prof. Dr. Olaf Dössel (University of Karlsruhe) Modelling and Imaging Electrophysiology and Contraction of the Heart Prof. Dr. Heinz-Otto Peitgen (University of Bremen/MeVis) Challenges and Problems of Quantitative Radiology Prof. Dr. Dr. h.c. Peter M. Schlag (Clinics for Surgery and Oncology, Charité) Duties of the Section CTAC of the German Society of Surgery For financial support of the RPT and MRNV 2007 workshop I would like to thank the Research Centre Jülich. Warm thanks go to the members of the local organization team: Tobias Bildhauer, Holger Dörle, Dimitri Geraskin, Anke Hülster, Marie-Sophie Lafontaine, Birgit Lentz, Dr. Kerstin Lüdtke-Buzug, Volker Luy, May Oehler, Gisela Niedzwetzki, Waltraud Ott and Dirk Thomsen. Without their help the conference and these proceedings would not have been possible. Many thanks go to the following cooperating societies: DGBMT (German Society of Biomedical Engineering) of VDE, CTAC (Section for Minimally Invasive, Computer and Telematics Assisted Surgery of the German Society of Surgery), DPG (German Society of Physics) and EMB German section of IEEE. On behalf of all authors I would also like to thank Eva Hestermann-Beyerle and Monika Lempe (Springer Publisher Heidelberg) for their help in the preparation of these proceedings. Remagen/Lübeck, March 2007 Thorsten M. Buzug Conference Chair Contents Invited Paper Modelling and Imaging Electrophysiology and Contraction of the Heart Olaf Dössel, Dima Farina, Matthias Mohr, Matthias Reumann, Gunnar Seemann and Daniel L. Weiss...................................................................3 Part I Medical Imaging Influence of Corrections During Image Reconstruction on the Spatial Resolution of ClearPET Neuro Christine Steenkamp, Simone Weber, Brigitte Gundlich, Patrick Musmann and Thorsten M. Buzug................................................................................................19 Dynamic Reconstruction for the ClearPETTM Neuro using Temporal B-Splines Brigitte Gundlich, Patrick Musmann and Simone Weber.....................................25 Local Compensation for Respiratory Motion in List-mode PET Ralph Brinks and Marc Busch..............................................................................31 Hybrid Imaging with SPECT/CT - Presentation of 5 Cases S. Berg, B.-I. Börner, H. Rasch, J. Müller-Brand and G. Bongartz.....................37 The(cid:540)-MLEM Algorithm: An Iterative Reconstruction Technique for Metal Artifact Reduction in CT Images May Oehlerand Thorsten M. Buzug.....................................................................42 Quantification of Tissue Microcirculation by Dynamic MRI and CT: Comparative Analysis of Signal-Time Courses Measured in Muscle Tissue G. Brix, J. Griebel, S. Delorme and F. Kiessling..................................................48 X Advances in Medical Engineering A Numerical Investigation of RF Heating Effects on Implants During MRI Compared to Experimental Measurements Jens Stenschke, Dan Li, Maike Thomann, Gregor Schaefers and Waldemar Zylka....................................................................................................53 Real Time Neuronavigation Using 3-D Ultrasound and MRI in Patients with Brain Tumor Martin Engelhardt, Christian Hansen, Bernhard Brendel, Stephanie Hold, Christopher Brenke, Ioannis Pechlivanis, Albrecht Harders, Helmut Ermert and Kirsten Schmieder.................................................................................................59 Vasodynamics of the Murine Arteria Saphena by Optical Coherence Tomography Julia Walther, Sven Meißner, Gregor Müller, Alexander Krüger, Henning Morawietz and Edmund Koch................................................................64 An Imaging System in the Sub Millimeter Area Christian Krebs, Thorsten M. Buzug and Dirk Nüßler.........................................69 Mutual Attraction of Oscillating Microbubbles Michiel Postema, Michał Mleczko and Georg Schmitz.........................................75 A new Imaging Data Fusion System for Application in Neurosurgery and Multimodality Phantoms for System Evaluation Julia Oestreich, Falk Uhlemann, Tobias Meyer, Annett Werner, Matthias Kirsch and Ute Morgenstern............................................................................................81 CCD-Video Endoscope Subjected to X-Ray Lucas Pfaffmann, Ronny Hübl and Thorsten M. Buzug........................................87 MRI Based Attenuation Correction for Brain PET Images Elena Rota Kops, Peng Qin, Mattea Müller-Veggian and Hans Herzog.............93 Integration of Functional Data (PET) into Brain Surgery Planning and Neuronavigation Stefan Vollmar, Jürgen A. Hampl, Lutz Kracht and Karl Herholz.......................98 Comparison of long-T Suppression Techniques for 3D Ultrashort 2 Echo-Time Imaging Ulrike Blume, Jürgen Rahmer, Peter Börnert and Dietrich Holz.......................104 Scatter Analysis of the ClearPET™ Neuro using Monte Carlo Simulations Anna M. Fulterer, Stephan Schneider, Brigitte Gundlich, Patrick Musmann, Simone Weber and Thorsten M. Buzug...............................................................109 Contents XI Multi-Modality-Imaging for Radiosurgery Planning of Arteriovenous Malformations Klaus-D. Hamm, Cornelia Eger, Gunnar Surber, Gabriele Kleinert, Rene Aschenbachand Joachim Klisch................................................................115 Image Based Analysis of Bone Graft Samples made by 3D Printing Using Conventional and Synchrotron-Radiation-Based Micro-Computed Tomography S. H. Irsen, B. Leukers, C. Tille, F. Beckmann, B. Müller, T. M. Buzug and H. Seitz.........................................................................................................121 SPECT-CT in Maxillofacial Surgery B.-I. Boerner, S. Berg, P. Juergens, A. Robertson and K. Schwenzer-Zimmerer...............................................................................127 Part II Medical Image Processing High Performance 2D/3D-Registration for Patient Positioning in Radiotherapy Frank Heinze, André Kupetz and Jürgen Roßmann............................................133 Modelling Tumour Growth Patterns with Non-Rigid Image Registration Andreas Mang, William R. Crum, Oscar Camara, Julia A. Schnabel, Gisele Brasil Caseiras, Thorsten M. Buzug, Hans R. Jäger, Tarek A. Yousry and David J. Hawkes..........................................................................................139 Segmentation and Navigation Support of Clinical Data Sets to Simulate the Bronchoscopy and Rhinoscopy Christian Dold, Ulrich Bockolt, Marcus Roth, Claus Peter Heussel, Jan Gosepath and Georgios Sakas............................................................................................145 Analysis of Body Surfaces in a Body-Fixed Coordinate System Burkhard Drerup and Stefan Kraneburg............................................................151 Deconvolution of Medical Ultrasound Data with Consideration of the Pressure Field, the Excitation Pulse and Focussing Holger J. Hewener and Robert Lemor................................................................157 Evaluation and Enhancement of a Procedure for Generating a 3D Bone Model Using Radiographs Sebastian Gollmer, Rainer Lachner and Thorsten M. Buzug.............................163