Table Of Content

Advanced Materials for Biomedical Applications This textbook discusses the synthesis, processing, design, simulation, and characterization of biomaterials for biomedical applications. It synergizes exploration related to various properties and functionalities in the biomedical feld through extensive theoretical and experimental modeling. It further presents advanced integrated design and nonlinear simulation prob- lems occurring in the biomedical engineering feld. It will serve as an ideal reference text for senior undergraduate and graduate students, and aca- demic researchers in felds including biomedical engineering, mechanical engineering, materials science, ergonomics, and human factors. This book • Employs a problem-solution approach, where, in each chapter, a spe- cifc biomedical engineering problem is raised and its numerical and experimental solutions are presented. • Covers recent developments in biomaterials such as OPMF/KGG biocomposites, PEEK-based biomaterials, PF/KGG biocomposites, oil palm mesocarp fber/KGG biocomposite, and polymeric resorbable materials for orthopedic, dentistry, and shoulder arthroplasty applications. • Discusses mechanical performance and corrosive analysis of biomaterials for biomedical applications in detail. • Presents advanced integrated design and nonlinear simulation prob- lems occurring in the biomedical engineering feld. • Presents biodegradable polymers for various biomedical applications over the last decade owing to their non-corrosion in the body, biocom- patibility, and superior strength in growing state. • Synergizes exploration related to various properties and functionalities in the biomedical feld through extensive theoretical and experimental modeling. Advances in Manufacturing, Design and Computational Intelligence Techniques Series Editor: Ashwani Kumar Advanced Materials for Biomedical Applications Ashwani Kumar, Yatika Gori, Avinash Kumar, Chandan Swaroop Meena, and Nitesh Dutt For more information about this series, please visit: https://www.routledge. com/Advances-In-Manufacturing-Design-andComputational-Intelligence- Techniques/book-series/%20CRCAIMDCIT Advanced Materials for Biomedical Applications Edited by Ashwani Kumar, Yatika Gori, Avinash Kumar, Chandan Swaroop Meena, and Nitesh Dutt First edition published 2023 by CRC Press 6000 Broken Sound Parkway NW, Suite 300, Boca Raton, FL 33487-2742 and by CRC Press 4 Park Square, Milton Park, Abingdon, Oxon, OX14 4RN CRC Press is an imprint of Taylor & Francis Group, LLC © 2023 selection and editorial matter, Ashwani Kumar, Yatika Gori, Avinash Kumar, Chandan Swaroop Meena and Nitesh Dutt; individual chapters, the contributors Reasonable eforts have been made to publish reliable data and information, but the author and publisher cannot assume responsibility for the validity of all materials or the consequences of their use. 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For works that are not available on CCC please contact [email protected] Trademark notice: Product or corporate names may be trademarks or registered trademarks and are used only for identifcation and explanation without intent to infringe. ISBN: 9781032356068 (hbk) ISBN: 9781032356075 (pbk) ISBN: 9781003344810 (ebk) DOI: 10.1201/9781003344810 Typeset in Sabon by codeMantra “This book is dedicated to all engineers, researchers, and academicians”. Contents Preface ix Acknowledgments xiii Editors xv Contributors xix 1 Recent advancements and future trends in next-generation materials for biomedical applications 1 AVINASH KUMAR, ANKA DATTA, ASHWANI KUMAR, AND ABHISHEK KUMAR 2 Advanced materials in biological implants and surgical tools 21 ANKA DATTA, AVINASH KUMAR, ASHWANI KUMAR, ABHISHEK KUMAR, AND VARUN PRATAP SINGH 3 Design and fabrication of augmented glenoid implants in total shoulder arthroplasty 45 CHAMAIPORN SUKJAMSRI AND VAMSI KRISHNA PASAM 4 Fabrication and cost optimization of 3D printed mandible for applications in dentistry 67 ANIL KUMAR BIRRU, AMANDEEP KAUR, AND KHUNDRAKPAM NIMO SINGH 5 Synthesis, properties, and applications of PEEK-based biomaterials 81 S. SATHISHKUMAR, P. JAWAHAR, AND PRASUN CHAKRABORTI 6 Morphology and Dielectric Characteristics of OPMF/KGG biocomposites 109 V. SRIKANTH, K. RAJA NARENDER REDDY, AND R. SAI KUMAR vii viii Contents 7 Physical Properties of Surface Modification Impact on Coir Fiber/KGG biocomposites 121 V. SRIKANTH, K. RAJA NARENDER REDDY, AND M. KEERTHIKA 8 Thermo-Mechanical and Morphological analysis of PF/KGG bio-composites 133 V. SRIKANTH, K. RAJA NARENDER REDDY, P. ANIL KUMAR, AND K. PUNNAM CHANDER 9 Posture analysis: current status and future trends 145 ARNAB SARMAH, SATOSHI ITO, AND SUBRAMANI KANAGARAJ 10 Turing test to validate perceptually reduced model for needle insertion simulation 163 RAVALI GOURISHETTI AND M. MANIVANNAN 11 Microfluidics-based isolation of circulating tumor cells 185 ANJU R. BABU, ADHARSH RAJ M. K., AND BANSOD SNEHA BHARAT 12 Advanced abrasive-based nano-finishing process parameter study for biomedical implants 201 CHINU KUMARI AND SANJAY KUMAR CHAK 13 Thermal and dynamic mechanical analysis of oil palm mesocarp fiber/Kondagogu gum biocomposites 219 V. SRIKANTH AND K. RAJA NARENDER REDDY 14 Biomedical study of femur bone fracture and healing 235 ASHWANI KUMAR, ARUN KUMAR SINGH GANGWAR, AVINASH KUMAR, CHANDAN SWAROOP MEENA, VARUN PRATAP SINGH, NITESH DUTT, ARBIND PRASAD, AND YATIKA GORI 15 Bio-based environmentally benign polymeric resorbable materials for orthopedic fixation applications 251 ARBIND PRASAD, GOURHARI CHAKRABORTY, AND ASHWANI KUMAR Index 267 Preface Advanced Materials for Biomedical Applications consists of the synthesis, processing, design, simulation, and characterization of biomaterials for biomedical applications. Advanced materials for biomedical applications are the central theme of the book. Biomaterials are used in bone plates, joint replacement, bone cement, surgical sutures, clips and staples to close wounds, pins and screws to stabilize fractures, surgical mesh, breast implants, artifcial ligaments and tendons, dental implants for teeth stabi- lization, blood vessel prostheses, heart valves, vascular grafts, stents, nerve conduits, skin repair devices, intraocular lenses in eye surgery, contact lenses, drug delivery systems, etc. There is a huge demand for biomedical fxations devices and implants. The resorbable material plays a vital role in developing and mimicking the bone. From the industry point of view, many processing techniques are researched in the biomedical domain in a very cost-effective way. Many conventional metals such as SS304, titanium alloys, and magnesium alloys have many biomedical limitations. So, there is a need of the hour to introduce new materials and their manufacturing techniques to the medical world. This book content is helpful to practitio- ners in felds of orthopedic, dental, and cardiology departments. Chapters 1 and 2 provide details about the recent developments in biomaterials and their broad applications. Chapter 1 deals with future trends in next-generation smart materials for biomedical applications. Smart materials may now provide wonderful capabilities such as controlled treatments by fne-tuning certain stimulus agents to improve therapeutic effciency. Dual- or multistimuli-responsive smart materials, which may activate sev- eral functionalities on a single smart nanomaterial, have lately received increased attention in order to enhance illness diagnostics. In addition, Chapter 2 deals with biological implants and surgical tool materials. A vast range of medical, assistive, and surgical instruments have been developed to improve human life. The aging population, accidents, and sports-related injuries are driving the ever-increasing need for ortho-, dental, cardiologic, ophthalmic, and IVD equipment, as well as enhanced diagnostic tests, in the worldwide medical device market. ix