Additive Manufacturing Processes in Biomedical Engineering: Advanced Fabrication Methods and Rapid Tooling Techniques

243 Pages·2022·17.242 MB·English

by  Atul Babbar, Ankit Sharma, Vivek Jain, Dheeraj Gupta

Additive Manufacturing
Processes in Biomedical
Engineering
This book covers innovative breakthroughs in additive manufacturing processes
used for biomedical engineering. More and more, 3D printing is selected over
traditional manufacturing processes, especially for complex designs, because of the
many advantages, such as fewer restrictions, better production cost savings, higher
quality control, and accuracy.
Current challenges and opportunities regarding material, design, cost savings,
and efficiency are covered along with an outline of the most recent fabrication
methods used for converting biomaterials into integrated structures that can fit best
in anatomy while still obtaining the necessary architecture, mechanical reliability,
biocompatibility, and antibacterial characteristics needed. Additional chapters
also focus on selected areas of applications, such as bionics, affordable prostheses,
implants, medical devices, rapid tooling, and drug delivery.
Additive Manufacturing Processes in Biomedical Engineering: Advanced
Fabrication Methods and Rapid Tooling Techniques acts as a firsthand reference
for commercial manufacturing organizations which are mimicking tissue organs by
using additive manufacturing techniques. By capturing the current trends of today’s
manufacturing practices this book becomes a one-stop resource for manufacturing
professionals, engineers in related disciplines, and academic researchers.
Sustainable Manufacturing Technologies:
Additive, Subtractive, and Hybrid
Series Editors
Chander Prakash, Sunpreet Singh,
Seeram Ramakrishna, and Linda Yongling Wu
This book series offers the reader comprehensive insights of recent research
breakthroughs in additive, subtractive, and hybrid technologies while emphasizing
their sustainability aspects. Sustainability has become an integral part of all
manufacturing enterprises to provide various techno-social pathways toward
developing environmental friendly manufacturing practices. It has also been found
that numerous manufacturing firms are still reluctant to upgrade their conventional
practices to sophisticated sustainable approaches. Therefore this new book series is
aimed to provide a globalized platform to share innovative manufacturing mythologies
and technologies. The books will encourage the eminent issues of the conventional
and non-conventual manufacturing technologies and cover recent innovations.
Advances in Manufacturing Technology
Computational Materials Processing and Characterization
Edited by Rupinder Singh, Sukhdeep Singh Dhami, and B. S. Pabla
Additive Manufacturing for Plastic Recycling
Efforts in Boosting A Circular Economy
Edited by Rupinder Singh and Ranvijay Kumar
Additive Manufacturing Processes in Biomedical Engineering
Advanced Fabrication Methods and Rapid Tooling Techniques
Edited by Atul Babbar, Ankit Sharma, Vivek Jain, Dheeraj Gupta
For more information on this series, please visit: www.routledge.com/Sustainable-
Manufacturing-Technologies-Additive-Subtractive-and-Hybrid/book-series/CRC
SMTASH
Additive Manufacturing
Processes in Biomedical
Engineering
Advanced Fabrication Methods and
Rapid Tooling Techniques
Edited by
Atul Babbar, Ankit Sharma,
Vivek Jain, and Dheeraj Gupta
First edition published 2023
by CRC Press
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Library of Congress Cataloging‑in‑Publication Data
Names: Babbar, Atul, editor.
Title: Additive manufacturing processes in biomedical engineering : advanced fabrication
methods and rapid tooling techniques / edited by Atul Babbar, Ankit Sharma, Vivek Jain,
and Dheeraj Gupta.
Description: First edition. | Boca Raton : CRC Press, [2023]
Series: Sustainable manufacturing technologies: additive, subtractive, and hybrid | Includes
bibliographical references and index.
Summary: “Current challenges and opportunities regarding material, design, cost savings,
and efficiency are covered along with an outline of the most recent fabrication methods
used for converting biomaterials into integrated structures that can fit best in the anatomy
while still obtaining the necessary architecture, mechanical reliability, biocompatibility,
and anti-bacterial characteristics needed. Additional chapters will also focus on selected
areas of applications such as bionics, affordable prostheses, implants, medical devices,
rapid tooling and drug delivery”—Provided by publisher.
Identifiers: LCCN 2022004315 (print) | LCCN 2022004316 (ebook) | ISBN 9781032109725
(hardback) | ISBN 9781032109732 (paperback) | ISBN 9781003217961 (ebook)
Subjects: LCSH: Biomedical materials. | Additive manufacturing—Materials.
Classification: LCC R857.M3 A373 2023 (print) | LCC R857.M3 (ebook) |
DDC 610.28/4—dc23/eng/20220401
LC record available at https://lccn.loc.gov/2022004315
LC ebook record available at https://lccn.loc.gov/2022004316
ISBN: 978-1-032-10972-5 (hbk)
ISBN: 978-1-032-10973-2 (pbk)
ISBN: 978-1-003-21796-1 (ebk)
DOI: 10.1201/9781003217961
Typeset in Times
by Apex CoVantage, LLC
Contents
Editors ......................................................................................................................vii
List of Contributors ...................................................................................................ix
Chapter 1 Recent Advancements of Additive Manufacturing for
Patient-Specific Drug Delivery .............................................................1
Prakash Katakam, Shanta Kumari Adiki, and
Soumya Ranjan Satapathy
Chapter 2 Additive Manufacturing for the Development of Biological
Implants, Scaffolds, and Prosthetics ...................................................27
Atul Babbar, Vivek Jain, Dheeraj Gupta, Ankit Sharma,
Chander Prakash, Vidyapati Kumar, and Kapil Kumar Goyal
Chapter 3 Additive Manufacturing Process for the Development
of Orthosis of Foot .............................................................................47
Manak L. Jain, Nalinakash S. Vyas, Anil Mulewa, and
Sanjay G. Dhande
Chapter 4 The Application of Additive Manufacturing Technology in the
Era of COVID-19 Pandemic: A State-of-the-Art Review ..................65
Raj Agarwal, Jaskaran Singh, and Vishal Gupta
Chapter 5 Relevance of Bio-Inks for 3D Bioprinting .........................................81
Bhargav Prajwal Pathri, Mohd. Shahnawaz Khan,
and Atul Babbar
Chapter 6 Additive Manufacturing of Polymers for Biomedical
Applications .......................................................................................99
Subrata Mondal
Chapter 7 Additive Manufacturing for Presurgical and Postsurgical
Planning: A State-of-the-Art Review ...............................................117
Satadru Kashyap
v
vi Contents
Chapter 8 Additive Manufacturing in Biomedical Engineering: Present
and Future Applications ...................................................................143
Vidyapati Kumar, Chander Prakash, Atul Babbar, Shubham
Choudhary, Ankit Sharma and Amrinder Singh Uppal
Chapter 9 Additive Manufacturing of Biomaterials: Classification,
Techniques, and Application ............................................................165
Sudip Dasgupta and Sambit Ray
Chapter 10 Role of 3D Printing and Chitosan-Hydrogel-Based Modifiers
in Drug Delivery ...............................................................................205
Lalita Chopra and Jasgurpreet Singh Chohan
Index ......................................................................................................................225
Editors
Dr. Atul Babbar is working as an assistant professor in the Mechanical Engineering
Department of SGT University, Gurugram. He has been teaching students in aca-
demics and research fields. He is a Level 2 Non-Destructive Testing Engineer cer-
tified by the American Society of Non-Destructive Testing. His research interests
include biomedical, three- and four-dimensional printing, and conventional/noncon-
ventional machining and is not limited to these. He has authored several research
articles and book chapters in various international/national Web of Science and
Scopus journals. He has been granted numerous national and international patents.
He has been reviewing research articles of various peer-reviewed SCI- and Scopus-
indexed journals.
Dr. Ankit Sharma is currently working as an assistant professor at Chitkara College
of Applied Engineering of Chitkara University. He has completed his doctoral from
the Thapar Institute of Engineering and Technology. He has authored numerous
national and international publications in Scopus- and Web of Science–indexed jour-
nals. His research interests include hybrid machining, additive manufacturing, and
others. He has vast experience in the industry as well as academics. He has been
granted with numerous national and international patents.
Dr. Vivek Jain received his PhD in 2012 from the Indian Institute of Technology
Roorkee, India, M.Tech. in 2009 from Guru Nanak Dev Engineering College,
Ludhiana, India with first class. He graduated in 1998 from Rajiv Gandhi College
of Engineering, Research and Technology, Nagpur University, India, with first
class. At present, he works as an associate professor in the Mechanical Engineering
Department of Thapar Institute of Engineering & Technology, Patiala. He has vast
experience, including 14 years of teaching and two years of industrial experience. His
research interests include biomedical, machining, composites, and surface engineer-
ing but are not limited to these. He has published in various international/national
journals. He has also filed three Indian patents. He is also handling one research
project funded by DST (India).
Dr. Dheeraj Gupta is currently an associate professor in the Department of
Mechanical Engineering at the Thapar Institute of Engineering & Technology,
Patiala, India. He obtained his BE in mechanical engineering from Shri Govindram
Seksaria Institute of Technology and Science, Indore, India, and master’s and doc-
toral degrees from the Indian Institute of Technology Roorkee, Roorkee, India. He
has more than 10 years of teaching and research experience. He has worked on a
European Union–funded project in Lisbon, Portugal. He has published more than
70 articles in journals and presented at conferences. He has filed two Indian Patents
on microwave processing of metals. Currently, he is a principal investigator for an
Indian government–funded project.
vii

Contributors
Shanta Kumari Adiki currently working in Sarojini Naidu Vanita Pharmacy Maha
Vidyalaya, Hyderabad, Telangana, India.
Raj Agarwal received an M.Tech degree in production engineering from Thapar
Institute of Engineering and Technology Patiala, Punjab, India, in 2019. He is now
a research scholar in the Department of Mechanical Engineering at the Thapar
Institute of Engineering and Technology Patiala. Furthermore, he has published arti-
cles in several international journals as well as papers, and book chapters in the areas
of additive manufacturing and biomedical engineering. His research interests include
additive manufacturing, biomechanics, biomaterials, rapid prototyping, artificial
intelligence, and machine learning for advanced manufacturing. His current work-
ing focuses on the diagnosis, prediction, and treatment of diseases using machine
learning.
Atul Babbar is working as an assistant professor in the Mechanical Engineering
Department of SGT University, Gurugram. He has been teaching students in aca-
demics and research fields. His research interests include biomedical, three- and
four-dimensional printing, and conventional/nonconventional machining and are not
limited to these.
Jasgurpreet Singh Chohan has been working as an associate professor in the
Department of Mechanical Engineering at Chandigarh University, India, since
October 2017. Dr. Chohan performed his doctoral research on improving the sur-
face characteristics of hip implants fabricated through a three-dimensional printing
process. He has more than 12 years of experience in research and teaching at the
graduate and postgraduate levels. His areas of specialization are additive manufac-
turing, hybrid machining, biomedical implants, advanced composites, metamateri-
als, human factor engineering, and multicriteria decision-making. He has filed six
patents, authored four books and 12 books chapters, and published more than 52
articles in international journals and conferences.
Lalita Chopra has teaching experience of 13 years and presently works as an assis-
tant professor in the Department of Chemistry, University Institute of Sciences,
Chandigarh University, Gharuan, Mohali. Her research work includes the synthesis
and characterization of biopolymer-based graft copolymers and crosslinked graft
copolymers for their application as metal ion sorption from wastewater. She had pub-
lished more than 30 research papers in reputed journals and attended and presented
research papers in more than 20 conferences and seminars.
Shubham Choudhary is working as an assistant professor in the Department of
Mechanical Engineering at Ajay Kumar Garg Engineering College. His research
ix