Koneman’s Color Atlas and Textbook of Diagnostic Microbiology

4942 Pages·2016·148.42 MB·English

by  Deirdre L. Church

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Koneman’s Color Atlas and Textbook
of Diagnostic Microbiology
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Copyright © 2017 Wolters Kluwer.
Copyright © 2005 Lippincott Williams & Wilkins. All rights reserved. This book is protected by copyright.
No part of this book may be reproduced or transmitted in any form or by any means, including as
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Printed in China
Library of Congress Cataloging-in-Publication Data Names: Procop, Gary W., author.
Title: Koneman’s color atlas and textbook of diagnostic microbiology / Gary W. Procop, Deirdre L. Church,
Geraldine S. Hall, William M. Janda, Elmer W. Koneman, Paul C. Schreckenberger, Gail L. Woods.
Other titles: Color atlas and textbook of diagnostic microbiology Description: Seventh edition. |
Philadelphia : Wolters Kluwer Health, [2017]
| Preceded by Koneman’s color atlas and textbook of diagnostic microbiology / Washington C. Winn Jr.
… [et al.]. 6th ed. c2006. |
Includes bibliographical references and index.
Identifiers: LCCN 2016002803 | ISBN 9781451116595 (hardback) | eISBN 9781469829401 | VST
9781469836164
Subjects: | MESH: Microbiological Phenomena | Microbiological Techniques |
Laboratory Manuals Classification: LCC QR67 | NLM QW 25 | DDC 616.9/041—dc23 LC record
available at http://lccn.loc.gov/2016002803
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including any warranties as to accuracy, comprehensiveness, or currency of the content of this work.
This work is no substitute for individual patient assessment based on healthcare professionals’ examination
of each patient and consideration of, among other things, age, weight, gender, current or prior medical
conditions, medication history, laboratory data, and other factors unique to the patient. The publisher does
not provide medical advice or guidance, and this work is merely a reference tool. Healthcare professionals,
and not the publisher, are solely responsible for the use of this work, including all medical judgments, and
for any resulting diagnosis and treatments.
Given continuous, rapid advances in medical science and health information, independent professional
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DEDICATION
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In Remembrance of Our Former Colleagues and Co-Authors Wash —We
particularly remember your leadership in the College of American Pathology
and as the editor-in-chief of the sixth edition of this text. You are sorely missed.
Steve —We particularly remember your leadership on the American Board of
Pathology and in Infectious Disease Pathology. You are sorely missed.
Gerri —We particularly remember you as the consummate educator, whom all
the students loved, and for your leadership in the American Society for
Microbiology and other national organizations. You, too, are sorely missed, and
this edition of this text would not have been possible without you - thanks.
Washington C. Winn Jr, MD, MBA
Director, Clinical Microbiology Laboratory Fletcher Allen Health Care
Professor of Pathology
University of Vermont College of Medicine Burlington, Vermont
Stephen D. Allen, MD
Professor of Pathology and Laboratory Medicine, Indiana University School of
Medicine Director, Division of Clinical Microbiology, Clarian Health—
Methodist, Indiana University, and Riley Hospitals Chief, Clinical Microbiology
Laboratory, Roudebush Veterans Affairs Hospital Pathologist, Wishard
Memorial Hospital Indianapolis, Indiana
Geraldine S. Hall, PhD, D(ABMM) Section Head, Clinical
Microbiology Cleveland Clinic
Professor of Pathology
Cleveland Clinic Lerner College of Medicine of Case Western Reserve
University Cleveland, Ohio
AUTHOR DEDICATIONS
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To Tamera and London—the best wife and son a guy could have. The Best of the
Best!
Gary W. Procop, MD
To my husband Gord and family for all their support Deirdre L. Church, MD,
PhD
Thanks for the support of my husband Geraldine S. Hall, PhD
To my parents, Robert and Geraldine, my brothers, Robert and Martin, and to
Matthew, my life partner.
William M. Janda, PhD
In recognition of the ongoing hard work and dedication of microbiology
technologists Elmer W. Koneman, MD
I thank my wife Ann for her immense support and patience during the prolonged
writing phase of this work and for her 45-plus years of steadfast love and
encouragement. I also thank my son Adam for his creation of the Web ID
Program used for identification of bacteria, which is described in detail in
Chapters 6 and 7 of this text.
Paul C. Schreckenberger, PhD
In loving memory of my father Gail L. Woods, MD
Foreword
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T
he diagnostic process for infectious diseases is complex. An astute
clinician may be able to make a clinical diagnosis based on the history,
presenting features, physical examination, and epidemiologic exposures,
including relevant travel. For example, pneumonia is a clinical diagnosis albeit
with radiographic confirmation. Establishing an etiologic diagnosis may be
much more difficult and is dependent on obtaining a relevant specimen of
interpretable quality, swift reliable transport, and the testing repertoire of the
supporting clinical microbiology laboratory. Moreover, presenting features of
different causative agents often overlap and an infectious process may involve
multiple organ systems, thereby adding further complexity to the task of
establishing an etiologic diagnosis on which specific antimicrobial therapy
depends. Indeed without an accurate and timely etiologic diagnosis, empirical
treatment ensues or is prolonged, which may consist of multiple antimicrobial
agents, those with unnecessarily broad activity, or both. This increases the risk
of adverse drug reactions, alters the patient’s microbiome, and promotes
selection of resistant mutants that indirectly put other patients at risk. Such
collateral damage emphasizes only the need for rapid and accurate tests wisely
deployed for the optimal outcome of patient care.
Thus, the founding objective of Koneman’s Color Atlas and Textbook of
Diagnostic Microbiology was to provide a clear exposition of procedures
routinely employed in the laboratory identification of microbial agents causing
infectious diseases. Since its first edition in 1979, the recognition and emergence
of new infectious agents; better tools for their microbiologic diagnosis; more
immunocompromised patients due to organ and stem cell transplantation,
chemotherapy of malignancies, and immune-modulating agents; and a changing
environment both of care and exposures have vastly complicated the quest for an
etiologic diagnosis. These transformative developments have only accelerated
since the sixth edition in 2006.
Fortunately, the tools available for the challenges at hand have also expanded