Kirk, Alison Fiona (2003) Promoting and maintaining physical activity in people with type 2 diabetes. PhD thesis. http://theses.gla.ac.uk/1994/ Copyright and moral rights for this thesis are retained by the author A copy can be downloaded for personal non-commercial research or study, without prior permission or charge This thesis cannot be reproduced or quoted extensively from without first obtaining permission in writing from the Author The content must not be changed in any way or sold commercially in any format or medium without the formal permission of the Author When referring to this work, full bibliographic details including the author, title, awarding institution and date of the thesis must be given Glasgow Theses Service http://theses.gla.ac.uk/ theses@gla.ac.uk PROMOTING AND MAINTAINING PHYSICAL ACTIVITY IN PEOPLE WITH TYPE 2 DIABETES by Alison Fiona Kirk (BSc) A Doctoral Thesis Submitted in fulfilment for degree the the partial of requirements of Doctor Philosophy of University Glasgow of Department Medicine Therapeutics of and 2003 ABSTRACT The benefits frequent for of regular, physical activity and exercise the management of Type 2 diabetes documented. Current American College Sports Medicine are well of (ACSM) for guidelines physical activity recommend that people should aim to least accumulate 30 intensity 5 days at minutes of moderate physical activity a week or 20 60 to high intensity 3 5 days continuous minutes of moderate to exercise, to a week. Around 80 Type 2 diabetes do To percent of people with not achieve these guidelines. date, research that addresses the promotion of physical activity in people with Type 2 diabetes has been limited. The the successful results of a pilot study evaluating in Type 2 effectiveness of exercise consultation to promote physical activity people with diabetes 5 led development PhD. This builds over weeks to the of this thesis on the foundations intervention 12 the the this of pilot study and evaluates effectiveness of over in Type 2 diabetes. months people with Accurate habitual is key importance to this to assessment of physical activity of research Accelerometers the true the examine effect of exercise consultation on physical activity. have become for Studies a popular objective method physical activity measurement. investigating have been the to validity of accelerometers restricted children and young Prior PhD further investigate to the to adults. main research a pilot study was conducted Computer Science Applications (CSA) the the to accuracy of and uniaxial accelerometer in Type 2 diabetes. 13 Type 2 diabetes measure physical activity people with people with (8M 5F, 54.2±6.5yrs, BMI 33.4±4.1) Participants mean age were recruited. walked at a brisk daily living (e. slow, normal and pace and performed other activities g. stair hoovering, loaded bags loaded climbing, carrying shopping and pushing a shopping During trolley at the normal walking pace). each activity steady state oxygen uptake breath by breath (Cosmed K4b2) (Vo2ml/kg/min) was measured using a portable system CSA the and activity counts/min were recorded using accelerometers worn at waist, ankle and wrist. demonstrated The this results of study oxygen uptake and activity counts at all increase increased (p<0.05). placements significantly as walking speed accelerometer bags loaded for Oxygen the the trolley carrying and pushing shopping were uptake higher (p0.05). From baseline 12 increase in the to months a significant was recorded for (p0.05). The to group, with no significant months control group decrease in from baseline 6 12 recorded a significant oxygen uptake to and months (p<0.05). Significant between differences for in the group were recorded change systolic blood HbAI, fibrinogen from baseline 6 (p<0.05) in to total pressure, and months and from baseline 12 (p=0.03 ). In both life to cholesterol months quality of questionnaires on the to most sub-scales experimental group recorded small moderate positive effect size from baseline 6 12 In to the scores and months. comparison control group recorded from baseline 6 12 A to to small moderate negative effect size scores and months. between difference from baseline 12 in the to the significant group of change months functioning SF-36 (p

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