Yearbook of Intensive Care 997 and Emergency Medicine Edited by J.-L. Vincent Springer-Verlag Berlin Heidelberg GmbH Yearbook of Intensive Care and Emergency Medicine 1997 Edited by J.-L. Vincent With 186 Figures and 120 Tables Springer Prof. fean-Louis Vincent Clinica} Director, Department of Intensive Care Erasme Hospital, Free University of Brussels Route de Lennik 808, B-1 070 Brussels, Belgium ISBN 978-3-662-13452-8 ISBN 978-3-662-13450-4 (eBook) DOI 10.1007/978-3-662-13450-4 ISSN 0942-5381 This work is subject to copyright. All rights are reserved, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illus trations, recitation, broadcasting, reproduction on microfilms or in any other ways and storage in data banks. 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SPIN: 10554174 19/3133-5 4 3 2 1 O-Printed on acid-free paper Contents Basic Mechanisms in Sepsis and ARDS Importance of Cell Wall Components of Gram-Positive Bacteria in Gram-Positive Septic Shock 3 (KM Kengatharan and C Thiemermann) Inflammatory Responses During Human Endotoxemia .... 14 (D Pajkrt, T van der Poll, and SJH van Deventer) Activation of Nuclear Factor-1<B in Sepsis and ARDS . . . . .. 31 (IW Christman, TS Blackwell, and MP Clark) The Cytokine Response to Hemorrhagic Shock . . . . . . . .. 42 (IM Kane and TR Billiar) Endothelial Cell Adhesion Molecule Expression in Acutely Inflamed Tissues .................... 52 (MJ Eppihimer and DN Granger) TNF in Septic Shock and Cerebral Malaria . . . . . . . . . . .. 63 (R Lucas, PM Suter, and GE Grau) Interleukin-1-Mediated Acute Lung Injury. . . . . . . . . . .. 74 (BM Hybertson and JE Repine) Cytokine-Networks and ARDS . . . . . . . . . . . . . . . .. 83 (PG Jorens and LL Bossaert) Disordered Apoptosis as a Mechanism for Adverse Outcome 91 (E Lin, SE Calvano, and SF Lowry) Apoptosis in the Resolution of Systemic Inflammation . . . . . 100 (IC Marshall and RWG Watson) New Therapeutic Interventions in Sepsis Cytokine-Mediated Enhancement of Host Defense ....... 111 (AJ Lechner and GM Matuschak) VI Contents Is it Beneficial to Augment or to Inhibit Neutrophil Function in Severe Infections and Sepsis? . . . . . . . . . . . . . . . . . . 123 (W Karzai and K Reinhart) Hemofiltration in Sepsis and Septic Shock . . . . . . . . . . . . 133 (P Rogiers, H Zhang, and JL Vincent) Extracorporal Techniques to Accelerate Clearance ofTNF-a and IL-l~ in Septic Patients .............. 140 (M van Deuren and JW van der Meer) Clinical Trials for the Evaluation of Sepsis Therapies . . . . . . 149 (DM Foster and GS Doig) Outcome from Sepsis and Organ Failure Prognostic Factors in Pre-Septic States .......... 161 (M Poeze and G Ramsay) Determinants of Outcome from Sepsis and Septic Shock .... 168 (GM Wray and C] Hinds) The Logistic Organ Dysfunction System ............. 180 (JR Le Gall, J Klar, and S Lemeshow) Nitric Oxide Nitric Oxide: A Modulator of the Inflammation Response ... 197 (P Kubes) Cytokine Regulation of Inducible Nitric Oxide Synthase .... 211 (J Cohen, T] Evans, and LA Keith) Activation of Poly-(ADP-Ribose) Synthetase by Peroxynitrite . 217 (C Szabo) Clinical Effects of Cell-Free Hemoglobin, a Scavenger of Nitric Oxide, in Septic Shock . . . . . . . . . . . . . . . 230 (RG Kilbourn, J DeAngelo, and J Bonaventura) Cardiovascular Failure in Sepsis Mechanisms of Decreased Cardiac Function in Sepsis ..... 243 (KR Walley) Septic Myocardial Dysfunction: Role of Cytokines and Nitric Oxide . . . . . . . . . . . . . . . . 256 (A Kumar and JE Parrillo) Contents VII O Transport in the Peripheral Circulation in Sepsis 277 2 (0 Eichelbroenner, FM BIoos, and WJ Sibbald) Use and Misuse of Catecholamines: Combination in Septic Shock Patients ............ .. 289 (C Martin, X Viviand, and F Po tie) Cardiorespiratory Failure Cardiorespiratory Physiology and Pathophysiology in Pregnancy . . . . . . . . . . . . . . . . 305 (SE Lapinsky) Pulmonary Embolism ....................... 317 (RP Dellinger) Cardiac Crisis Emergency Evaluation of Acute Ischemic Coronary Syndrome 329 (WB Gibler and MR Sayre) Serious Arrhythmias and Anesthesia . . . . . . . . . . 339 (AG Aya, C Van Roy, and JE de La Coussaye) Percutaneous Mechanical Circulatory Assistance .... .... 356 (P Urban) Peri -Operative Applications of Transesophageal Echocardiography . . . . . . . . . . .... 366 (CA Visser and 0 Kamp) Fluid Administration Prehospital Fluid Replacement .................. 383 (U Kreimeier and K Peter) Volume Therapy: New Aspects of an Old Topic? . . . . . . . . . 399 (J Boldt, D Mentges, and M Papsdorf) Albumin Physiology in the Septic and Post-Operative Patient . 411 (M Margarson and N Soni) Effects of Hemoglobin in Sepsis . . . . . . . . . . . . .. 424 (SR Fisher, HG Bone, and DL Traber) VIII Contents Quality of Life Benefit from Avoiding Allogenic Blood Transfusion .......... 442 (RF Nease, TW Croghan, and B Littenberg) Airway Management Tracheostomy ............................ 457 (G Bishop, K Hillman, and P Bristow) Percutaneous Dilatational Tracheostomy . . . . ...... 470 (LWE van Heurn, PRG Brink, and G Ramsay) Ventilation with an Unprotected Airway During Cardiac Arrest 483 (V Wenzel, AH Idris, and KH Lindner) Non-Invasive Ventilatory Support Non-Invasive Ventilation . . . . . . . . . .......... 495 (G Conti, M Antonelli, and A Gasparetto) Workload of Non-Invasive Ventilation in Acute Respiratory Failure . . . . . . . . . . . . . . . 505 (IC Chevrolet and P Jolliet) New Modes of Ventilatory Support in Spontaneously Breathing Intubated Patients ......... 514 (R Stocker, B Fabry, and C Haberthilr) Ventilatory Support Patient-Ventilator Interactions . . . . . . . . . . . . . 537 (VM Ranieri, S Grasso, and A Brienza) Hypoxemic Respiratory Failure . . . . .. . .......... 547 (RG Brower, HE Fessler, and C Shanholtz) Inflection Point and Alveolar Recruitment in ARDS ...... 556 (M Mergoni, A Volpi, and A Rossi) Tracheal Gas Insufflation in ARDS ................ 568 (F Brunet, M Monchi, andJ Dall'ava Santucci) Current Status of Prone Position in ARDS . . . ..... 579 (M Martinez and L Blanch) Experience in Liquid Ventilation ................. 585 (RB Hirschi) Contents IX Pulmonary Infections The Inflammatory Response in Pneumonia ........... 595 (A Torres, MEl Ebiary, and C Manton) The Challenge of Pseudomonas aeruginosa Pneumonia .... 607 (SJ Peacock and CS Garrard) Respiratory Syncytial Virus Infection in Children . . . . . . . . 625 (J Hammer and CJL Newth) Rationale for Surfactant Therapy in Pneumonia . . . . . . . . . 638 (A van't Veen, D Gammers, and B Lachmann) Gut Dysfunction Intestinal Epithelial Hyperpermeability ........ ..... 657 (MP Fink) Regional Capnometry ....................... 669 (B Vallet) Assessment of Gastric Mucosal Perfusion by Laser-Doppler Flowmetry ...... . ........... 677 (J Duranteau, P Sitbon, and E Vicaut) Severe Acute Necrotizing Pancreatitis ............. 687 (DL Wyncoll and RJ Beale) Nutrition Early Enteral Feeding Improves Outcome ............ 701 (GP Zaloga and PR Roberts) Nutrition and Survival ....................... 715 (RD Griffiths, TEA Palmer, and C Jones) Neurologic Failure Focal Cerebral Ischemia ...................... 727 (S Kuroda, P Siesjo, and BK Siesjo) Cerebral Blood Flow in Acute Brain Injury . . . . . . . . . . .. 739 (PJD Andrews, MJ Souter, and L Mascia)