Lenka Lhotska · Lucie Sukupova Igor Lacković · Geoffrey S. Ibbott (Eds.) Volume 68/2 World Congress on Medical Physics and Biomedical Engineering 2018 June 3–8, 2018, Prague, Czech Republic (Vol. 2) IFMBE Proceedings Volume 68/2 Series editor Ratko Magjarevic Deputy Editors Fatimah Ibrahim Igor Lacković Piotr Ładyżyński Emilio Sacristan Rock The InternationalFederation forMedicalandBiologicalEngineering, IFMBE,isafederation ofnationalandtransnationalorganizationsrepresentinginternationallytheinterestsofmedical andbiologicalengineeringandsciences.TheIFMBEisanon-profitorganizationfosteringthe creation,disseminationandapplicationofmedicalandbiological engineeringknowledgeand the management of technology for improved health and quality of life. Its activities include participationintheformulationofpublicpolicyandthedisseminationofinformationthrough publications and forums. Within the field of medical, clinical, and biological engineering, IFMBE’saimsaretoencourageresearchandtheapplicationofknowledge,andtodisseminate information and promote collaboration. The objectives of the IFMBE are scientific, technological, literary, and educational. The IFMBE is a WHO accredited NGO covering the full range of biomedical and clinical engineering,healthcare,healthcaretechnologyandmanagement.Itisrepresentingthroughits 60 member societies some 120.000 professionals involved in the various issues of improved health and health care delivery. IFMBE Officers President: James Goh, Vice-President: Shankhar M. Krishnan Past President: Ratko Magjarevic Treasurer: Marc Nyssen, Secretary-General: Kang Ping LIN http://www.ifmbe.org More information about this series at http://www.springer.com/series/7403 Lenka Lhotska Lucie Sukupova (cid:129) ć Igor Lackovi Geoffrey S. Ibbott (cid:129) Editors World Congress on Medical Physics and Biomedical Engineering 2018 – June 3 8, 2018, Prague, Czech Republic (Vol. 2) 123 Editors Lenka Lhotska Igor Lacković CIIRC Faculty of Electrical Engineering Czech TechnicalUniversity inPrague andComputing Prague University of Zagreb Czech Republic Zagreb Croatia LucieSukupova Institute of Clinical andExperimental Geoffrey S. Ibbott Medicine Department ofRadiation Physics Prague TheUniversity of TexasMD Anderson Czech Republic CancerCenter Houston, TX USA ISSN 1680-0737 ISSN 1433-9277 (electronic) IFMBE Proceedings ISBN978-981-10-9037-0 ISBN978-981-10-9038-7 (eBook) https://doi.org/10.1007/978-981-10-9038-7 LibraryofCongressControlNumber:2018940876 ©SpringerNatureSingaporePteLtd.2019 Thisworkissubjecttocopyright.AllrightsarereservedbythePublisher,whetherthewholeorpartofthematerialis concerned,specificallytherightsoftranslation,reprinting,reuseofillustrations,recitation,broadcasting,reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation,computersoftware,orbysimilarordissimilarmethodologynowknownorhereafterdeveloped. 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Printedonacid-freepaper ThisSpringerimprintispublishedbytheregisteredcompanySpringerNatureSingaporePteLtd. partofSpringerNature Theregisteredcompanyaddressis:152BeachRoad,#21-01/04GatewayEast,Singapore189721,Singapore Preface This book presents the proceedings of the IUPESM World Congress on Biomedical Engi- neering and Medical Physics, a triennially organized joint meeting of medical physicists, biomedicalengineers,andadjoininghealthcareprofessionals.Besidesthepurelyscientificand technological topics, the 2018 Congress will also focus on other aspects of professional involvement in health care, such as education and training, accreditation and certification, healthtechnologyassessment,andpatientsafety.TheIUPESMmeetingisanimportantforum formedicalphysicistsandbiomedicalengineersinmedicineandhealthcaretolearnandshare knowledge, and to discuss the latest research outcomes and technological advancements as well as new ideas in both medical physics and biomedical engineering field. Biomedical engineering and medical physics represent challenging and rapidly growing areas. Building on the success of the previous World Congresses, the aim of the World Congress 2018 is to continue in bringing together scientists, researchers, and practitioners from different disciplines, namely from mathematics, computer science, bioinformatics, biomedical engineering, medical physics, medicine, biology, and different fields of life sci- ences, so that they can present and discuss their research results. We hope that the World Congress 2018 will serve as a platform for fruitful discussions between all attendees, where participantscanexchangetheirrecentresults,identifyfuturedirectionsandchallenges,initiate possible collaborative research, and develop common languages for solving problems in the realm of biomedical engineering and medical physics. Following a thorough peer-reviewed process, we have finally selected 498 papers. The ScientificCommitteewouldliketothankthereviewersfortheirexcellentjob.Thearticlescanbe found inthe proceedingsand are divided intothe maintracksand special sessions. The papers showhowbroadthespectrumoftopicsinbiomedicalengineeringandmedicalphysicsis. The editors would liketothank alltheparticipants fortheirhigh-quality contributions and Springer for publishing the proceedings of the World Congress. Prague, Czech Republic Lenka Lhotska Prague, Czech Republic Lucie Sukupova Zagreb, Croatia Igor Lacković Houston, USA Geoffrey S. Ibbott March 2018 v Organizing Committees Congress Coordinating Committee Chair Kin Yin Cheung, Chair, IOMP, Hong Kong Members Howell Round, IOMP, New Zealand Slavik Tabakov, IOMP, UK Virginia Tsapaki, IOMP, Greece James Goh, IFMBE, Singapore Kang Ping Lin, IFMBE, Chinese Taipei Herb Voigt, co-opted, IFMBE, USA † Monique Frize, co-opted, IFMBE, Canada Congress Organizing Committee Co-chairs Jaromir Cmiral, Czech Republic, BME Libor Judas, Czech Republic, MedPhys Secretaries Frantisek Lopot, Czech Republic, BME Karel Nechvil, Czech Republic, MedPhys Members Financial Committee Co-chairs Martin Mayer, Czech Republic, BME Vít Richter, Czech Republic, MedPhys Scientific Committee Co-chairs Lenka Lhotska, Czech Republic, BME Lucie Sukupova, Czech Republic, MedPhys Publicity Committee Chair Martina Novakova, Czech Republic, BME, MedPhys Education Committee Co-chairs Jiri Hozman, Czech Republic, BME Irena Koniarova, Czech Republic, MedPhys vii viii OrganizingCommittees Financial Committee Co-chairs Martin Mayer, Czech Republic, BME Vit Richter, Czech Republic, MedPhys Members Jan Hanousek, Czech Republic, BME Anchali Krisanachinda, IOMP Mark Nyssen, IUPESM, IFMBE Vaclav Poljak, Czech Republic, MedPhys Scientific Committee Co-chairs Geofrey Ibbott, IOMP Lenka Lhotska, Czech Republic, BME Igor Lackovic, IFMBE Lucie Sukupova, Czech Republic, MedPhys Members Magdalena Bazalova-Carter, Canada Carmel Caruana, Malta Tomas Cechak, Czech Republic Paul Chang, Singapore Kin Yin Cheung, Hong Kong, China Jiri Chvojka, Czech Republic Matej Daniel, Czech Republic Marie Davidkova, Czech Republic Harry Delis, IAEA Pavel Dvorak, Czech Republic Ludovic Ferrer, France Martin Falk, Czech Republic Christian Gasser, Sweden Csilla Gergely, France Susanna Guatelli, Australia Jens Haueisen, Germany Jan Havlik, Czech Republic Jiří Hozman, Czech Republic Marjan Hummel, The Netherlands Leonidas D. Iassemidis, USA Tom Judd, USA Peter Knoll, Austria Radim Kolar, Czech Republic Jana Kolarova, Czech Republic Christian Kollmann, Austria Irena Koniarova, Czech Republic David Korpas, Czech Republic Vladimir Krajca, Czech Republic Jan Kremlacek, Czech Republic Petr Marsalek, Czech Republic Deborah Van Der Merwe, IAEA Karel Nechvil, Czech Republic OrganizingCommittees ix Chris Nuggent, UK Pirkko Nykänen, Finland Hakan Nystrom, Sweden Pawel Olko, Poland Maria Perez, WHO Vaclav Porod, Czech Republic Kevin Prise, UK Ivo Provaznik, Czech Republic Jaroslav Ptáček, Czech Republic Vladimir Rogalewicz, Czech Republic Simo Saarakkala, Finland Ioannis Sechopoulos, The Netherlands Milan Sonka, USA Olga Stepankova, Czech Republic Lucie Sukupova, Czech Republic Krystina Tack, USA Annalisa Trianni, Italy Jiri Trnka, Czech Republic Virginia Tsapaki, Greece Adriana Velazquez, WHO Frantisek Vlcek, Czech Republic Jan Vrba, Czech Republic Kevin Warwick, UK Martha Zequera Diaz, Columbia Program Committee Co-chairs Jaromir Cmiral, Czech Republic, BME Libor Judas, Czech Republic, MedPhys Members Lenka Lhotska, Czech Republic, BME Frantisek Lopot, Czech Republic, BME Karel Nechvil, Czech Republic, MedPhys Martina Novakova, Czech Republic, BME Lucie Sukupova, Czech Republic, MedPhys Publicity Committee Chair Martina Novakova, Czech Republic Members Pavla Buricova, Czech Republic Michele Hilts, Canada Jeannie Hsiu Ding Wong, Malaysia Akos Jobbagy, Hungary Luiz Kun, USA Pavla Novakova, Czech Republic Magdalena Stoeva, Bulgaria Tae-Suk Suh, Republic of Korea Jaw-lin Wang, Chinese Taipei x OrganizingCommittees Education Committee Co-chairs Jiri Hozman, Czech Republic, BME Irena Koniarova, Czech Republic, MedPhys Members Jiri Kofranek, Czech Republic, BME Vladimír Krajca, Czech Republic, BME Simo Saarakkala, Finland, BME Ioannis Sechopoulos, The Netherlands, MedPhys Professional Standards Committee Co-chairs David Korpas, Czech Republic, BME Libor Judas, Czech Republic, MedPhys Members John Damilakis, Greece, MedPhys Michele Hilts, Canada Jeannie Hsiu Ding Wong, Malaysia Tomas Kron, Australia, MedPhys Siew Lok Toh, Singapore, BME Yakov Pipman, USA, MedPhys Kang Ping Lin, Chinese Taipei, BME Jaroslav Ptacek, Czech Republic, MedPhys Christoph Trauernicht, South Africa, MedPhys Publication Committee Chair Vladimir Marik, Czech Republic Co-chair Igor Lacković, Croatia International Advisory Board (BME) Co-chairs James Goh, Singapore Ratko Magjarevic, Croatia Members Guillermo Avendano C., Chile Paulo De Carvalho, Portugal Jaromir Cmiral, Czech Republic Fong Chin Su, Chinese Taipei David Elad, Israel Yubo Fan, China