WOMEN, HORMONES AND THE MENSTRUAL CYCLE i This page intentionally left blank ii Women, hormones and the menstrual cycle Herbal and medical solutions from adolescence to menopause Second edition Ruth Trickey iii For Kirrian First published in 1998 This edition published in 2003 Copyright © Ruth Trickey 1998, 2003 © Botanical illustrations Lauren Black 1998 All rights reserved. No part of this book may be reproduced or transmitted in any form or by any means, electronic or mechanical, including photocopying, recording or by any information storage and retrieval system, without prior permission in writing from the publisher. The Australian Copyright Act 1968 (the Act) allows a maximum of one chapter or 10 per cent of this book, whichever is the greater, to be photocopied by any educational institution for its educational purposes provided that the educational institution (or body that administers it) has given a remuneration notice to Copyright Agency Limited (CAL) under the Act. Allen & Unwin 83 Alexander Street Crows Nest NSW 2065 Australia Phone:(61 2) 8425 0100 Fax: (61 2) 9906 2218 Email: [email protected] Web: www.allenandunwin.com National Library of Australia Cataloguing-in-Publication entry: Trickey, Ruth, 1953– . Women, hormones and the menstrual cycle: herbal and medical solutions from adolescence to menopause. 2nd ed. Bibliography. Includes index. ISBN 1 86508 980 X. 1. Women—Health and hygiene. 2. Menstrual cycle. 3. Hormones. I. Title. 618.172 Set in 11/13 pt Sabon by DOCUPRO, Canberra Printed by Griffin Press, South Australia iv Contents WOMEN, HORMONES AND THE MENSTRUAL CYCLE CONTENTS Figures and tables vi Boxes viii Acknowledgments ix Introduction x Section A SETTING THE SCENE 1 The history of natural medicine 3 Section B THE WAY THINGS ARE 2 Anatomy 23 3 Menstruation and the menstrual cycle 33 Section C MAINTAINING ORDER AND BALANCE 4 Hormones 53 5 Maintaining hormonal balance 65 6 Prostaglandins 86 Section D HORMONAL LIFESTAGES 7 Adolescence 97 8 The menstruating years and PMS 114 9 Menopause 153 Section E WHEN THINGS GO WRONG 10 The usual suspects 209 11 Menorrhagia 231 12 Metrorrhagia 251 13 Amenorrhoea and oligomenorrhoea 268 14 Dysmenorrhoea 289 15 Endometriosis and adenomyosis 305 16 Ovarian cysts 327 Section F SETTING IT RIGHT 17 Food for health 365 18 Oestrogen-like compounds in plants 394 19 Herbs 420 20 Drugs and surgery 500 Appendix Patterns of disharmony 537 Glossary 555 Notes 564 Index 645 CONTENTS v v Figures and tables FIGURES AND TABLES Figures 1.1 The humoral theory 6 1.2 The qualities 8 1.3 The elements 8 2.1 The anatomy of the female genitalia 24 2.2 Internal reproductive organs 28 2.3 Cross-section of the internal reproductive organs 28 2.4 Ovarian follicle maturation 29 2.5 The endometrial cycle in relation to plasma levels of ovarian steroid hormones 32 3.1 The menstrual cycle 39 3.2 Pictorial blood loss assessment chart (PBAC) 43 3.3 Breast self-examination (BSE) 49 4.1 Steroid hormone pathways 54 4.2 The entero-hepatic circulation of oestrogens 59 6.1 Essential fatty acid pathways 89 10.1 The three phases of stress 211 16.1 Pathways to insulin resistance and polycystic ovarian syndrome 336 16.2 Pathogensis and treatment of PCOS 341 16.3 Possible interactions between herbs and enzymes in the pilo-sebaceous unit 354 A.1 Physiology according to the humoral theory 553 Tables 1.1 The three major medical systems from antiquity 4 1.2 The major differences between the old and new paradigms of medicine and health 14 1.3 The most common natural medicine disciplines practised in Australia and New Zealand 20 3.1 Standard classification for cervical cell changes 48 5.1 Basal body temperature graph 78 8.1 The common symptoms of PMS 116 8.2 Menstrual symptom questionnaire 127 vi WOMEN, HORMONES AND THE MENSTRUAL CYCLE vi 8.3 DSM-IV criteria for Premenstrual Dysphoric Disorder 137 8.4 Questionnaire for suspected functional hypoglycaemia 149 9.1 Normal ranges for FSH at various stages in the menstrual cycle 161 9.2 Menopausal symptom index 162 9.3 Different recommendations for the treatment of peri- menopausal PMS and menopausal symptoms 165 9.4 Common drugs and bone density 187 9.5 Bone density interpretations 189 9.6 Elemental mineral content in supplements 193 9.7 Sources of calcium 200 9.8 Osteoporosis questionnaire 201 11.1 Sources of iron 250 13.1 Medical evaluation of primary amenorrhoea when breast development is normal 269 13.2 Normal ranges of serum prolactin 14.1 Uterine tone 304 15.1 Bitter foods and herbs 326 16.1 Sources of magnesium 362 17.1 Approximate levels of proteins in common foods 379 17.2 Amounts of common foods providing 10 g fibre 393 18.1 Different classes of common phyto-oestrogens 397 18.2 Relative oestrogenic activity of phyto-oestrogens 397 18.3 Coumestrol content of foods 398 18.4 Binding affinity of various phyto-oestrogens for ERα and ERβ 405 18.5 Edible plants with recognised oestrogenic compounds 417 20.1 Factors associated with increased breast cancer risk 516 20.2 Factors associated with increased risk of cardiovascular disease 518 FIGURES AND TABLES vii vii Boxes BOXES Signs of health 15 Natural medicine associations 19 The well woman’s check list 47 Case study: Relative oestrogen deficiency 71 Zinc for growth and development 112 Functional hypoglycaemia 149 Check list for the mid-life woman 180 Factors influencing retention of calcium in the bone 185 Calcium—essential for bones 199 Body mass index (BMI) 218 The common causes of menorrhagia 232 The importance of iron 248 Common causes of bleeding between periods 252 Abnormal tissue tone 267 The common causes of secondary amenorrhoea 269 Blood quality 287 Irritable bowel syndrome 296 Uterine tone 303 Case study: Treatment and diet for endometriosis 323 The liver 324 Peony and liquorice combination 357 Examples of low GI foods 360 Magnesium 361 Test methods for assessing oestrogenicity 417 The uterine tonics 422 Reasons to avoid HRT 519 viii WOMEN, HORMONES AND THE MENSTRUAL CYCLE viii Acknowledgments ACKNOWLEDGMENTS I am indebted to the many colleagues and friends who contributed to the more than 70 000 words of new or updated information that was necessary to complete the second edition of this book. Thanks firstly to the other herbalist/naturopaths who I work with at Melbourne Holistic Health Group. Sandra Villella helped with menopause, osteoporosis and the latest information on the effects of declining androgens in women. Jenny Adams took on the daunting task of researching and collating the large amount of new information on phyto-oestrogens and Karen McElroy collected an equally large volume of the latest herbal medicine research. Sandra, Jenny and Karen also contributed information gained through their clinical and professional experiences and the material provided in the sections on the natural therapists’ approach has been contributed to, in no small way, through insights gathered during stimulating discussions at the clinic. Other herbalists, too numerous to mention, helped in a myriad of ways. Erin Collins helped with herbal research and gathering new information on endometriosis; Nick Burgess provided photos from his extensive collection of medicinal herbs for the front cover; and Michael Thomsen lent some of his files on herbal medicine. Thanks also to Judy Singer, Shu Yi Mann, Jill Birney and Kathleen McPherson. Many gynaecologists have helped with information and chapter reviews. Principal amongst these are Dr Claire Petterson, so vital for the first edition of the book, who contributed information on drugs, surgery and endometriosis; Dr Catharyn Stern for her generous help on poly- cystic ovarian syndrome; and Dr Helena Teede for her valuable advice on the amenorrhoea chapter. Tracey Reeves was my personal assistant and general researcher during a brief sojourn back in Australia and her practical, efficient and good-humoured approach to all things professional and personal saved the day during a two-month period of seven days a week and too many late nights to mention. Finally, I would like to thank Chris Cooke who helped with graphics, the various computer dramas and who provided some of the best resources of all—words of encouragement, a ready ear, and food on the table. Ruth Trickey Melbourne ACKNOWLEDGMENTS ix ix Introduction INTRODUCTION An earlier menarche, better nutrition, less pregnancies and a longer life expectancy mean that today’s woman will have many more periods in her lifetime than her ancestors did. The ‘average’ Australian woman can expect to menstruate from the age of twelve or thirteen until she is somewhere between 25 and 35 years old. She is then likely to become pregnant two or three times about every two years, breast-feeding for about three to nine months. Following her pregnancies, she can expect her cycle to remain fairly regular until she is about 50 years old when she will become menopausal. All up, the average Australian woman will have about 30 years of regular menstruation, totalling between 360 and 400 periods. Compared to this, women from earlier ages started to menstruate around fourteen or fifteen years old and were frequently married soon after. Child bearing began earlier and it was common for women to give birth many times if their fertility was not affected by sexually transmit- ted diseases, poor nutrition or indifferent health; or if they didn’t die in childbirth. Contraception was not as reliable as it is today, and the spacing between pregnancies was influenced by breastfeeding—both because breastfeeding naturally reduced fertility, and because it was commonly held that a breastfeeding woman should abstain from sex. (Sex was believed to bring on a woman’s period; and the return of the period was thought to deprive the baby of sustenance by diverting the breast milk—the ‘white blood’—from the breasts to the womb.) So, for most of their fertile years, these women were likely to be either pregnant or breastfeeding, and had an average of only 40 periods during their lifetime. Both the menstrual cycle and menstruation itself are easily affected: diet, lifestyle and stress will all have an impact on the ease and regularity of the cycle. These associations have become less obvious with the modern-day tendency to take an aspirin or go on the Pill the moment the first problem arises. But there is an increasing understanding of the delicacy of the menstrual cycle, of its dependency on nutrition and harmony. Many women want to control or treat their menstrual diffi- culties with commonsense and commonplace remedies which they can administer themselves, or use non-drug alternatives such as herbal medicines. x WOMEN, HORMONES AND THE MENSTRUAL CYCLE x
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