Smart Sensors, Measurement and Instrumentation 27 Robert LeMoyne Timothy Mastroianni Wearable and Wireless Systems for Healthcare I Gait and Reflex Response Quantification Smart Sensors, Measurement and Instrumentation Volume 27 Series editor Subhas Chandra Mukhopadhyay Department of Engineering, Faculty of Science and Engineering Macquarie University Sydney, NSW Australia e-mail: [email protected] More information about this series at http://www.springer.com/series/10617 Robert LeMoyne Timothy Mastroianni (cid:129) Wearable and Wireless Systems for Healthcare I fl fi Gait and Re ex Response Quanti cation 123 RobertLeMoyne Timothy Mastroianni Department ofBiological Sciences, Center Independent forBioengineering Innovation Pittsburgh, PA Northern ArizonaUniversity USA Flagstaff, AZ USA ISSN 2194-8402 ISSN 2194-8410 (electronic) Smart Sensors, Measurement andInstrumentation ISBN978-981-10-5683-3 ISBN978-981-10-5684-0 (eBook) https://doi.org/10.1007/978-981-10-5684-0 LibraryofCongressControlNumber:2017952009 ©SpringerNatureSingaporePteLtd.2018 Thisworkissubjecttocopyright.AllrightsarereservedbythePublisher,whetherthewholeorpart of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission orinformationstorageandretrieval,electronicadaptation,computersoftware,orbysimilarordissimilar methodologynowknownorhereafterdeveloped. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publicationdoesnotimply,evenintheabsenceofaspecificstatement,thatsuchnamesareexemptfrom therelevantprotectivelawsandregulationsandthereforefreeforgeneraluse. The publisher, the authors and the editors are safe to assume that the advice and information in this book are believed to be true and accurate at the date of publication. Neither the publisher nor the authorsortheeditorsgiveawarranty,expressorimplied,withrespecttothematerialcontainedhereinor for any errors or omissions that may have been made. The publisher remains neutral with regard to jurisdictionalclaimsinpublishedmapsandinstitutionalaffiliations. Printedonacid-freepaper ThisSpringerimprintispublishedbySpringerNature TheregisteredcompanyisSpringerNatureSingaporePteLtd. Theregisteredcompanyaddressis:152BeachRoad,#21-01/04GatewayEast,Singapore189721,Singapore In Memoriam: David Peduto (Lt. Col. US Army) (1954–2016) To a friend, valued research team member, and Patriot. Jonathan Swift Ph.D. (1932–2017) To an incredible teacher who made learning an adventure. “Think globally, and act locally!” Wes Stewart (1924–2017) Cousin Wes you are a dearly cherished member of our family and the personification of America’s Greatest Generation. You are deeply missed. I take comfort knowing everybody has an angel. To my wife, thank you for everything. Love Always. I would like to thank my Mother, Father, and brother for their support. “Nothing transcends the power of the human spirit.” from a homeless Vietnam Veteran and very loyal friend And in the wind he’s still alive. “Tobeatatiger,oneneedsabrother’shelp.” Chinese Proverb Thanks Tim. Chiri mo tsumoreba yama to naru. A favorite Japanese Proverb (in Romaji) Translation: Even dust piled up becomes a mountain. Preface The domain of wearable and wireless systems for biomedical and rehabilitation applications, such as through smartphones and portable media devices, is antici- patedtogrowexponentially.Evenfromthetimeofpresentingthedraftmanuscript ofthisbooktothetimeofpublication,theprevalenceofthissubjectisexpectedto undergo meaningful transformation and evolution. These devices enable wireless inertialsensorapplicationstoanassortmentofscenariospertainingtorehabilitation and therapy. Since2010whenLeMoyne,Mastroianni,andourresearchteamappliedanovel smartphone application for quantifying Parkinson’s disease tremor and gait quan- tification in the context of a wireless accelerometer, the opportunities have expanded considerably. The authors are delighted to provide a contribution to this exciting field with the anticipation of the considerable array of developments in years to follow. Please enjoy the knowledge and intellectual inspiration that our book provides with the goal of providing meaningful, robust, and optimal reha- bilitation for many. Flagstaff, USA Robert LeMoyne Pittsburgh, USA Timothy Mastroianni ix Contents 1 Wearable and Wireless Systems for Gait Analysis and Reflex Quantification..... .... .... .... .... .... ..... .... 1 1.1 Introduction .. .... ..... .... .... .... .... .... ..... .... 2 1.2 Summary of the Pending Chapters.. .... .... .... ..... .... 5 1.3 Conclusion ... .... ..... .... .... .... .... .... ..... .... 16 References. .... .... .... ..... .... .... .... .... .... ..... .... 17 2 Traditional Clinical Evaluation of Gait and Reflex Response by Ordinal Scale ... .... ..... .... .... .... .... .... ..... .... 21 2.1 Introduction .. .... ..... .... .... .... .... .... ..... .... 21 2.2 Ordinal Scale for Quantification of Reflex Response ..... .... 22 2.3 Ordinal Scale Technique for Gait... .... .... .... ..... .... 25 2.4 Ordinal Scale Strategy for Friedreich’s Ataxia . .... ..... .... 25 2.5 Transition to Wearable and Wireless Systems . .... ..... .... 26 2.6 Conclusion ... .... ..... .... .... .... .... .... ..... .... 27 References. .... .... .... ..... .... .... .... .... .... ..... .... 27 3 Quantification Systems Appropriate for a Clinical Setting.... .... 31 3.1 Introduction .. .... ..... .... .... .... .... .... ..... .... 31 3.2 Conventional Systems for Gait Analysis.. .... .... ..... .... 33 3.2.1 Foot Switches .... .... .... .... .... .... ..... .... 34 3.2.2 Electrogoniometers .... .... .... .... .... ..... .... 34 3.2.3 Electromyogram (EMG) .... .... .... .... ..... .... 35 3.2.4 Metabolic Analysis .... .... .... .... .... ..... .... 36 3.2.5 Optical Motion Cameras (Kinematics of Human Motion)... .... .... ..... .... 36 3.2.6 Force Plates. ..... .... .... .... .... .... ..... .... 38 3.3 Synergistic Operation of Clinical Gait Laboratory Resources for Gait Analysis and Associated Signal Processing. ..... .... 40 xi xii Contents 3.4 Electromechanical Techniques for Reflex Quantification... .... 41 3.5 Conclusion ... .... ..... .... .... .... .... .... ..... .... 42 References. .... .... .... ..... .... .... .... .... .... ..... .... 42 4 The Rise of Inertial Measurement Units . .... .... .... ..... .... 45 4.1 Introduction .. .... ..... .... .... .... .... .... ..... .... 45 4.2 Evolutionary Pathway for Inertial Sensors .... .... ..... .... 46 4.3 Application Scenarios for Accelerometer Systems .. ..... .... 47 4.4 Wireless Accelerometer Systems for Gait Analysis.. ..... .... 52 4.5 Conclusion ... .... ..... .... .... .... .... .... ..... .... 55 References. .... .... .... ..... .... .... .... .... .... ..... .... 55 5 Portable Wearable and Wireless Systems for Gait and Reflex Response Quantification. .... .... .... .... ..... .... 59 5.1 Introduction .. .... ..... .... .... .... .... .... ..... .... 59 5.2 First Generation Wireless Reflex Quantification Device... .... 60 5.3 Second Generation Wireless Reflex Quantification Device. .... 60 5.4 Third Generation Wireless Quantified Reflex Device ..... .... 61 5.5 Artificial Reflex System .. .... .... .... .... .... ..... .... 62 5.6 Wireless Accelerometer Reflex Quantification System Characterizing Response and Latency.... .... .... ..... .... 63 5.7 Fourth Generation Wireless Quantified Reflex Device .... .... 63 5.8 Gait Analysis Using Wearable and Wireless Accelerometer Nodes... .... .... ..... .... .... .... .... .... ..... .... 65 5.9 Virtual Proprioception.... .... .... .... .... .... ..... .... 67 5.10 Further Applications of Wearable and Wireless Inertial Sensor Systems for Gait Quantification... .... .... ..... .... 68 5.11 Conclusion ... .... ..... .... .... .... .... .... ..... .... 69 References. .... .... .... ..... .... .... .... .... .... ..... .... 70 6 Smartphones and Portable Media Devices as Wearable and Wireless Systems for Gait and Reflex Response Quantification . .... .... ..... .... .... .... .... .... ..... .... 73 6.1 Introduction .. .... ..... .... .... .... .... .... ..... .... 73 6.2 Smartphone Quantifying Gait as a Wireless Accelerometer Platform . .... .... ..... .... .... .... .... .... ..... .... 75 6.3 Post-processing and Numerical Analysis for the Acquired Acceleration Waveform for Gait.... .... .... .... ..... .... 77 6.4 Portable Media Device for Quantifying Gait as a Wireless Accelerometer Platform .. .... .... .... .... .... ..... .... 78 6.5 Smartphone Wireless Accelerometer Platform for Quantification of Prosthetic Gait.... .... .... .... ..... .... 79 6.6 Smartphone Wireless Gyroscope Platform for Quantification of Hemiplegic Reduced Arm Swing. .... .... .... ..... .... 80