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12 Pages·2011·1.45 MB·English

RESEARCH PARTNER IN
FOOD AND NuTRITION
RESEARCH PARTNER IN
FOOD AND NuTRITION
The world needs healthy, safe and sustainably-produced food
products more than ever. Within the framework of national and
international legislation, the agrifood sector launches over
15,000 product innovations a year. TNO develops methods and
produces research insights that enable innovation.
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INNOVATIONS IN HEALTHY,
SAFE AND SUSTAINABLE FOOD
The food industry is facing enormous governments in policy development. and product quality. The final
challenges. Today’s large-scale food With its broad knowledge, experience research area, Food Safety, develops
production negatively impacts our and expertise, TNO has an important methods for efficient safety
environment, and raw material role to play in the translation of assessment and risk management.
supplies are becoming exhausted. fundamental scientific insights into The research area focuses on
Population-associated pressures on innovative, tailor-made applications. issues of complex food matrices,
our planet will increase substantially TNO is a partner in several public- allergenicity, emerging risk
in the next decade, and the number private partnerships (PPPs) and open identification, in-line detection and
of people with obesity, diabetes and innovation networks in the Nether- controlling microbiological safety.
food allergies is on the rise. lands and the European union.
As globalization speeds up, the risk
of unmanageable food incidents TNO RESEARCH PROGRAMME
increases correspondingly. This particular TNO research
programme has three research
TO ACCELERATE INNOVATION areas. Food and Health develops
These developments require methods for short-term assessment
innovations in healthy and of the health effects of food
sustainably-produced food products, products. In Food Innovations, TNO
and a rigorous risk-management is developing a comprehensive
approach. TNO meets these approach that allows manufacturers
demands through its multidisciplinary to significantly shorten time-to-
research programme. The organi za- market for healthy and sustainable
tion develops methods and delivers innovations. The research area
insights that help the agrifood sector focuses on issues of product
to innovate quickly and that support formulas, production processes
FOOD SAFETy
FOOD AND
HEAlTH
FOOD INNOvATIONS
FOOD AND HEALTH
In today’s market, knowing the health effects of your products is essential.
Whether you supply a unique product to a specific sector, or put bread on
every breakfast table, consumers, retail partners, health professionals and
other stakeholders will ask about health.
When food and health is the issue, TNO is your trusted partner providing:
• Short term: regulatory consultancy on claims and scientific communications.
• Medium term: unique array of model systems, and human clinical trials.
• Long term: (co-financed) research partnerships.
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INNOVATIVE ASSESSmENTS
OF HEALTH EFFEcTS
TNO combines academic excellence, investigation and communication NuTRIENT SENSING
CRO expertise and knowledge of of health effects. Macronutrients are detected by
international markets and policies. our body and generate regulatory
Our ambition is to play a leading role GASTROINTESTINAL HEALTH responses including the onset
in the development of healthier food More and more is known about the of digestion and regulation of
products and concepts, in order to influence of the gi tract on health and prospective food intake. TNO is
benefit society. To achieve this goal, well being. TNO is exploring this field collaborating in an academic and
we have given each of our innovative using a unique set of expertise and industrial network, identifying new
research programs a specific focus. tools. Our proprietary family of in vitro physiological and molecular targets
gastrointestinal models (tiM) gives - and new approaches - to nutrient
MEASuRING HEALTH TNO a significant advantage in this sensing, which can be used to
TNO has developed an innovative research. tiM can be combined with optimize body-weight regulation.
concept to define and measure a broad array of in vivo, in silico and in Currently, the focus is on the small
health. Several challenge-tests have vivo models, metabolomics intestine. For the food industry,
been developed to measure the techniques, and challenge-tests in this project will give insight into
body’s ability to cope with external humans. Key research directions formulating functional foods for
stressors: the more resilient, the include the effect of intestinal weight management. This is relevant
healthier. Modern ‘omics’ techniques microflora metabolites on weight for serious public health problems
are indispensable to evaluate the management and appetite, and such as obesity and for patients
often subtle effects of food on health the relationship between nutrition, dealing with anorexia and disease-
parameters. One important goal is intestinal-barrier function and the related weight loss.
to define new biomarkers for health immune system in relation to chronic
and disease. This technique opens inflammation in fat tissue.
up many new possibilities for the
rewriting
THE DEFINITION
OF HEAlTH RAPID IN vITRO
aSSeSSMent of
PRObIOTIC
SuRvIvAbIlITy
deterMining
SubTlE HEAlTH
EFFECTS OF
vegetabLeS
FOOD INNOVATIONS
Product development and refor mulation can be very challen ging.
Changes in a product formula or recipe should maintain the
product’s desired qualities of flavour, texture, shelf-life and safety.
Moreover, product quality should go hand in hand with efficient and
sustainable produc tion processes. TNO’s compre hensive approach
to advising manu facturers enables them, in a faster and in a more
efficient way, to introduce new and improved products that meet the
demands of today’s markets.
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SOLVINg DEVELOpmENT
ISSUES EFFIcIENTLY
TNO works with a comprehensive networks. The ambition is to make in this area. ultimately, this provides
approach that empowers ingredient sure that improved products are label friendly solutions for ingre-
suppliers and food manufacturers to launched quickly and successfully on dients such as modified starches.
efficiently solve issues of product the market. The research programme Other ingredient innova tions include
development and reformulation. follows three interdependent paths. protein formula tions for improved
Clients can then significantly shorten oxygen and water barriers and
time-to-market for new and improved QuALITy healthy fibres from wheat and other
products. TNO’s method dynamically TNO solves quality issues that arise sources with excellent textural
acquires and seamlessly integrates from reformulation in particular properties.
knowledge of ingredients, production addressing the salt, sugar and
processes and product quality. New fat content of products. both PROCESSING
insights into ingredient interactions experimental and predictive TNO develops separation, drying and
provide leads for the optimisation of modelling tools are available to production processes that are energy
production processes and maintain product characteristics. efficient, reduce waste streams and
improvements in product quality. TNO also investigates new ways of improve product and ingredient
using ingredients to structure quality. Examples include drying
TNO makes an important contribution products such as mimicking the techniques such as Super Heated
to targets set by the government and texture of meat with vegetable Steam (SHS) and inkjet spray-drying.
industry for reformulating existing proteins. In addition TNO uses novel
food products into healthier processing methods such as
equivalents and for creating a INGREdIENTS electrospinning and rapid manu-
sustainable and secure food TNO has IP protected technologies facturing to create completely new
production chain. The organization for food production and modification ways to produce structured food
is partner in several national and that creates ‘greener’, ‘cleaner’ and products.
international open innovation healthier ingredients and innovations
PRINTED
wine-guMS
40% SAlT
REDuCTION aLgae-baSed
IN bACON Meat
SubSTITuTES
FOOD SAFETY
Efficient (food) safety assessment is becoming more and more
challenging. Product constituents are growing in number and variety.
For many substances the toxicological hazards and the allergy-
causing potential are unknown. Negative health effects of
components often manifest with a delay, and evaluation of
emerging food risks is difficult due to lack of data. TNO supports
manufacturers and governments by developing advanced methods
for (food) safety assessment and risk management.
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EFFIcIENT SAFETY ASSESSmENT
TNO is a world leader in (food) safety These include tools that measure emerging safety risks. ERIS helps to
assessment and risk management, concentrations of unknown com- anticipate food and feed safety crises
developing methods that allow pounds and that enable exclusion and issues and enables stakeholders
manufacturers and governments to of (geno)toxicity. Examples include to develop appropriate risk manage-
obtain rapid insight into the risks of physical-chemical screening methods ment strategies at an early stage.
complex products. In addition, TNO’s and (microbial) genomics techniques.
work on food allergy should deliver These methods are integrated into a IN-LINE dETECTION
more efficient assessment protocols safety assessment strategy. TNO has developed a unique,
and better understanding of factors tailor-made detection strategy that
determining allergenicity. As a partner ALLERGENICITy enables food manufacturers to
in several programmes for (open) Together with partners, TNO develops monitor product safety, quality and
innovation, TNO is also developing biological and physical/chemical tools authenticity in line. On request TNO
instruments for early detection of to predict, understand and prevent develops in line sensors, process and
emerging public health hazards to allergenicity of proteins and peptides, packaging control systems and
prevent food crises. which are then translated into a risk non-invasive detection equipment.
The ambition is to create a set assessment strategy. Examples are
of internationally-acknowledged an innovative probability-based CONTROLLING
assessment methods that accelerate method that enables assessment MICRObIOLOGICAL SAFETy
product and policy development and of food allergy risks and a large TNO offers tailor-made solutions
increase accuracy, while reducing database on allergic responses. for complex microbiological issues
emergency response times for related to safe and high quality food
emerging food incidents. TNO is EMERGING RISk IdENTIFICATION products and food processing
following five research approaches. SuPPORT systems. TNO’s new protocols and
TNO has developed a unique and analysis methods help the industry
COMPLEx FOOd MATRICES cost-efficient Emerging Risk improve the microbiological safety
TNO develops methods for the Identification Support service (ERIS) of food.
toxicological safety assessment. to identify and evaluate present and
IDENTIFICATION
of MicrobiaL
aLLergy
OuTbREAKS
inforMation
guideLineS
Manage newLy
FOuND RISKS
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TNO IN BRIEF
Our world is changing fast. Develop- funded research institute and, more disciplinary teams, support our
ments in society are radical and recently, as a modern application- vision.
often intangible: ageing, climate oriented innovator. Our vision of the
crisis, energy and raw material future centers on a society that TNO APPROACH: FOCuS ON
depletion, and security issues that provides prosperity and welfare for SEVEN RESEARCH THEMES
demand measures to secure the all. A society in which competitive- TNO wants to make a real difference:
foundations of our society for the ness and sustainability go hand in to generate solutions that address
long term. These challenges also hand, as we move forward together. key issues in society. We have
bring opportunities: they require for TNO sustains progress by applying therefore chosen to focus on
innovations, new technology and a scientific knowledge to solve the seven research themes of global
new way of thinking. complex issues confronted by significance that require new,
society, and using innovation to creative, comprehensive solutions.
A RELIAbLE kNOwLEdGE boost the competitiveness of Themes that match the pressing
PARTNER industry. The same qualities that issues of government, industry and
TNO was founded during the founded TNO still power our work the knowledge infrastructure. The
economic crisis of the 1930s, based today: knowledge, creativity, curiosity seven themes are:
on the conviction that new knowledge and idealism.
and technology is vital to economic – Healthy living
growth and social renewal. Such TNO’s strength lies in our ability to – Defence, Safety and Security
investment is crucial in times of combine diverse scientific expertise – transport and Mobility
crisis. These principles are now to create pioneering solutions: in – Information Society
more pertinent than ever. global partnerships with government, – Industrial Innovation
industry and relevant knowledge – Energy
TNO has supported government and institutions and ngos. over 4,000 – built Environment
industry with science, knowledge and TNO scientists, researchers and
innovation. Initially as a government- specialist support staff, in multi-
NEW CREATIvE
SOluTIONS
ClIENTS
All OvER THE
WORlD
SCIENTIFIC EXCEllENCE