Vitamin C in Health and Disease (Antioxidants in Health and Disease, Vol 5)

1359 Pages·1997·5.54 MB·English

by  Lester Packer

Vitamin C in Health and Disease
title:
Antioxidants in Health and Disease ; 5
author: Packer, Lester.
publisher: CRC Press
isbn10 | asin: 0824793137
print isbn13: 9780824793135
ebook isbn13: 9780585343587
language: English
Vitamin C--Health aspects, Ascorbic Acid--
subject physiology, Ascorbic Acid--therapeutic use,
Ascorbic Acid--chemistry.
publication date: 1997
lcc: QP772.A8V565 1997eb
ddc: 615/.328
Vitamin C--Health aspects, Ascorbic Acid--
subject: physiology, Ascorbic Acid--therapeutic use,
Ascorbic Acid--chemistry.
Vitamin C in Health and Disease
ANTIOXIDANTS IN HEALTH AND DISEASE
Series Editors
L P , P .D.
ESTER ACKER H
University of California
Berkeley, California
J F , P .D., M.D.
ÜRGEN UCHS H
Johann Wolfgang Goethe University
Frankfurt, Germany
1. Vitamin A in Health and Disease, edited by Rune Blomhoff
2. Biothiols in Health and Disease, edited by Lester Packer and
Enrique Cadenas
3. Handbook of Antioxidants, edited by Enrique Cadenas and Lester
Packer
4. Handbook of Synthetic Antioxidants, edited by Lester Packer and
Enrique Cadenas
5. Vitamin C in Health and Disease, edited by Lester Packer and
Jürgen Fuchs
Additional Volumes in Preparation
Lipoic Acid in Health and Disease, edited by Jürgen Fuchs, Lester
Packer, and Guido Zimmer
Flavonoids in Health and Disease, edited by Catherine Rice-Evans
and Lester Packer
Related Volumes
Vitamin E in Health and Disease: Biochemistry and Clinical
Applications, edited by Lester Packer and Jürgen Fuchs
Free Radicals and Oxidation Phenomena in Biological Systems,
edited by Marcel Roberfroid and Pedro Buc Calderon
Page i
Vitamin C in Health and Disease
edited by
Lester Packer
University of California
Berkeley, California
Jürgen Fuchs
Johann Wolfgang Goethe University
Frankfurt, Germany
Page ii
Library of Congress CataloginginPublication Data
Vitamin C in health and disease / edited by Lester Packer, Jürgen Fuchs.
p. cm.(Aantioxidants in health and disease ; 5)
Includes index.
ISBN 0-8247-9313-7 (hardcover : alk. paper)
1. Vitamin CHealth aspects. I. Packer, Lester. II. Fuchs,
Jürgen. III. Series.
[DNLM: 1. Ascorbic Acidphysiology. 2. Ascorbic Acid
therapeutic use. 3. Ascorbic Acidchemistry. W1 AN884 v.5 1997
/ QU 210 V8363 1997]
615'.328dc21
DNLM/DLC
for Library of Congress
97-7703
CIP
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Current printing (last digit):
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PRINTED IN THE UNITED STATES OF AMERICA
Page iii
SERIES INTRODUCTION
In June of 1992, 17 international researchers in the field of free radical
and antioxidant biology and preventive medicine met at the village of
Saas Fee, Switzerland, and drew up the Saas Fee Declaration to
recognize the importance of prevention in medicine and health. Since
then, hundreds of researchers from around the world have signed the
declaration:
Saas Fee Declaration
On the significance of antioxidants in preventive medicine.
1. The intensive research on free radicals of the past 15 years by
scientists worldwide has led to the statement in 1992 that antioxidant
nutrients may have major significance in the prevention of a number
of diseases. These include cardiovascular and cerebrovascular disease,
some forms of cancer and several other disorders, many of which may
be age-related.
2. There is now general agreement that there is a need for further work
at the fundamental scientific level, as well as in large-scale
randomized trials and in clinical medicine, which can be expected to
lead to more precise information being made available.
3. The major objective of this work is the prevention of disease. This
maybe achieved by use of antioxidants which are natural
physiological substances. The strategy should be to achieve optimal
intakes of these antioxidant nutrients as part of preventive medicine.
4. It is quite clear that many environmental sources of free radicals
exist, such as ozone, sunlight, and other forms of radiation, smog,
dust, and other atmospheric pollutants. The optimal intake of
antioxidants provides a preventive measure against these hazards.
5. There is a great need for improvement in public awareness of the
potential preventive benefits of antioxidant nutrient intake. There is
overwhelming evidence that the antioxidant nutrients such as vitamin
E, vitamin C, carotenoids, alpha-lipoic acid and others are safe even at
very high levels of intake.
6. Moreover, there is now substantial agreement that government
agencies, health professionals, and the media should promote
information transfer to the general public, particularly when evidence
exists that benefits for human health and public expenditure are
overwhelming.