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Vitamin C in Health and Disease (Antioxidants in Health and Disease, Vol 5) PDF

1359 Pages·1997·5.54 MB·English
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Vitamin C in Health and Disease title: Antioxidants in Health and Disease ; 5 author: Packer, Lester. publisher: CRC Press isbn10 | asin: 0824793137 print isbn13: 9780824793135 ebook isbn13: 9780585343587 language: English Vitamin C--Health aspects, Ascorbic Acid-- subject physiology, Ascorbic Acid--therapeutic use, Ascorbic Acid--chemistry. publication date: 1997 lcc: QP772.A8V565 1997eb ddc: 615/.328 Vitamin C--Health aspects, Ascorbic Acid-- subject: physiology, Ascorbic Acid--therapeutic use, Ascorbic Acid--chemistry. Vitamin C in Health and Disease ANTIOXIDANTS IN HEALTH AND DISEASE Series Editors L P , P .D. ESTER ACKER H University of California Berkeley, California J F , P .D., M.D. ÜRGEN UCHS H Johann Wolfgang Goethe University Frankfurt, Germany 1. Vitamin A in Health and Disease, edited by Rune Blomhoff 2. Biothiols in Health and Disease, edited by Lester Packer and Enrique Cadenas 3. Handbook of Antioxidants, edited by Enrique Cadenas and Lester Packer 4. Handbook of Synthetic Antioxidants, edited by Lester Packer and Enrique Cadenas 5. Vitamin C in Health and Disease, edited by Lester Packer and Jürgen Fuchs Additional Volumes in Preparation Lipoic Acid in Health and Disease, edited by Jürgen Fuchs, Lester Packer, and Guido Zimmer Flavonoids in Health and Disease, edited by Catherine Rice-Evans and Lester Packer Related Volumes Vitamin E in Health and Disease: Biochemistry and Clinical Applications, edited by Lester Packer and Jürgen Fuchs Free Radicals and Oxidation Phenomena in Biological Systems, edited by Marcel Roberfroid and Pedro Buc Calderon Page i Vitamin C in Health and Disease edited by Lester Packer University of California Berkeley, California Jürgen Fuchs Johann Wolfgang Goethe University Frankfurt, Germany Page ii Library of Congress CataloginginPublication Data Vitamin C in health and disease / edited by Lester Packer, Jürgen Fuchs. p. cm.(Aantioxidants in health and disease ; 5) Includes index. ISBN 0-8247-9313-7 (hardcover : alk. paper) 1. Vitamin CHealth aspects. I. Packer, Lester. II. Fuchs, Jürgen. III. Series. [DNLM: 1. Ascorbic Acidphysiology. 2. Ascorbic Acid therapeutic use. 3. Ascorbic Acidchemistry. W1 AN884 v.5 1997 / QU 210 V8363 1997] 615'.328dc21 DNLM/DLC for Library of Congress 97-7703 CIP The publisher offers discounts on this book when ordered in bulk quantities. For more information, write to Special Sales/Professional Marketing at the address below. This book is printed on acid-free paper. Copyright © 1997 by Marcel Dekker, Inc. All Rights Reserved. Neither this book nor any part may be reproduced or transmitted in any form or by any means, electronic or mechanical, including photocopying, microfilming, and recording, or by any information storage and retrieval system, without permission in writing from the publisher. Marcel Dekker, Inc. 270 Madison Avenue, New York, New York 10016 Current printing (last digit): 10 9 8 7 6 5 4 3 2 1 10 9 8 7 6 5 4 3 2 1 PRINTED IN THE UNITED STATES OF AMERICA Page iii SERIES INTRODUCTION In June of 1992, 17 international researchers in the field of free radical and antioxidant biology and preventive medicine met at the village of Saas Fee, Switzerland, and drew up the Saas Fee Declaration to recognize the importance of prevention in medicine and health. Since then, hundreds of researchers from around the world have signed the declaration: Saas Fee Declaration On the significance of antioxidants in preventive medicine. 1. The intensive research on free radicals of the past 15 years by scientists worldwide has led to the statement in 1992 that antioxidant nutrients may have major significance in the prevention of a number of diseases. These include cardiovascular and cerebrovascular disease, some forms of cancer and several other disorders, many of which may be age-related. 2. There is now general agreement that there is a need for further work at the fundamental scientific level, as well as in large-scale randomized trials and in clinical medicine, which can be expected to lead to more precise information being made available. 3. The major objective of this work is the prevention of disease. This maybe achieved by use of antioxidants which are natural physiological substances. The strategy should be to achieve optimal intakes of these antioxidant nutrients as part of preventive medicine. 4. It is quite clear that many environmental sources of free radicals exist, such as ozone, sunlight, and other forms of radiation, smog, dust, and other atmospheric pollutants. The optimal intake of antioxidants provides a preventive measure against these hazards. 5. There is a great need for improvement in public awareness of the potential preventive benefits of antioxidant nutrient intake. There is overwhelming evidence that the antioxidant nutrients such as vitamin E, vitamin C, carotenoids, alpha-lipoic acid and others are safe even at very high levels of intake. 6. Moreover, there is now substantial agreement that government agencies, health professionals, and the media should promote information transfer to the general public, particularly when evidence exists that benefits for human health and public expenditure are overwhelming.

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"Provides an up-to-the-minute, comprehensive analysis of the most recent theoretical and clinical developments in vitamin C research--integrating a wide variety of interdisciplinary studies into a single-source volume. Highlights the redox properties of vitamin C, including regeneration, participati
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