WWeesstteerrnn UUnniivveerrssiittyy SScchhoollaarrsshhiipp@@WWeesstteerrnn Electronic Thesis and Dissertation Repository 8-20-2013 12:00 AM VViioolleennccee aammoonngg CCooccaaiinnee aanndd SSiimmuullttaanneeoouuss CCooccaaiinnee aanndd AAllccoohhooll AAbbuusseerrss:: RReessuullttss ffrroomm aa CCrroossss--sseeccttiioonnaall SSttuuddyy ooff TTrreeaattmmeenntt CClliieennttss Sameer Imtiaz, The University of Western Ontario Supervisor: Dr. Samantha Wells, The University of Western Ontario A thesis submitted in partial fulfillment of the requirements for the Master of Science degree in Epidemiology and Biostatistics © Sameer Imtiaz 2013 Follow this and additional works at: https://ir.lib.uwo.ca/etd Part of the Epidemiology Commons RReeccoommmmeennddeedd CCiittaattiioonn Imtiaz, Sameer, "Violence among Cocaine and Simultaneous Cocaine and Alcohol Abusers: Results from a Cross-sectional Study of Treatment Clients" (2013). Electronic Thesis and Dissertation Repository. 1456. https://ir.lib.uwo.ca/etd/1456 This Dissertation/Thesis is brought to you for free and open access by Scholarship@Western. It has been accepted for inclusion in Electronic Thesis and Dissertation Repository by an authorized administrator of Scholarship@Western. For more information, please contact [email protected]. VIOLENCE AMONG COCAINE AND SIMULTANEOUS COCAINE AND ALCOHOL ABUSERS: RESULTS FROM A CROSS-SECTIONAL STUDY OF TREATMENT CLIENTS Thesis format: Monograph by Sameer Imtiaz Graduate Program in Epidemiology and Biostatistics A thesis submitted in partial fulfillment of the requirements for the degree of Master of Science The School of Graduate and Postdoctoral Studies The University of Western Ontario London, Ontario, Canada © Sameer Imtiaz 2013 Abstract A population known for substantial violence is the substance abuse treatment population. This study assessed: (1) extent of violence, (2) personality and mental health correlates of violence, and (3) sex differences in correlates of violence. Data were obtained from the Patterns and Consequences of Cocaine and Alcohol Use for Substance Abuse Treatment Clients Study (N = 403). Logistic regression with backward elimination procedures and modified Poisson regression were used to assess the study objectives. Violence was reported by 44% of treatment clients. Furthermore, number of other drugs used per week (RR: 1.124, 95% CI: 1.063 - 1.189) and aggressive personality (RR: 1.043, 95% CI: 1.031 – 1.055) were significantly associated with an increased likelihood of violence. Finally, there was no evidence for sex-differences in correlates of violence. These findings suggest that screening for violence and addressing pertinent risk factors during treatment may be needed to reduce violence within this population. Keywords Violence, physical aggression, substance abuse treatment, substance use disorder treatment, cocaine, alcohol, simultaneous use, drugs, aggressive personality and sex-differences ii Dedication “Let me hide in You From everything that distracts me from You, From everything that comes in my way When I want to run to You.” – Rabia Al-Adawiyya iii Acknowledgments I am indebted to several individuals whose continued guidance and support made this thesis a reality. I would like to begin by thanking the faculty in the Department of Epidemiology and Biostatistics for imparting their years of knowledge and experience. In particular, I am grateful to my thesis advisory committee, Drs. Greta Bauer, John Koval and Scott Macdonald, for providing critical feedback that improved the quality of this thesis substantially. Above all, I am most appreciative of my mentor, Dr. Samantha Wells, for acting as a constant source of inspiration, guidance and encouragement. Not only have I benefited from her mentorship, but I have also gained tremendously from the opportunities she provided me to develop as a scientist. I would further like to thank all my colleagues and friends in the Department of Epidemiology and Biostatistics for enriching my graduate experience. In particular, I am grateful to Ahmed, Alvin, Bryan, Jerry, Joseph, Kariym and Sonia for not only diversifying my perspective on life, but also making the last two years memorable. Finally, I would like to thank my family for being the cornerstone of support during this entire journey. I am forever grateful to my parents for the sacrifices they have made not only during this graduate experience, but life in general. Additionally, I am thankful to my sister and brother in law for providing me with two great sources of amusement and happiness that helped me focus beyond the thesis itself. Last but not least, I am thankful to my wife whose short presence has quantitatively and qualitatively modified my quality of life. Our marriage was perhaps the greatest motivation to complete this thesis on time. iv Table of Contents Abstract ............................................................................................................................... ii Dedication .......................................................................................................................... iii Acknowledgments.............................................................................................................. iv Table of Contents ................................................................................................................ v List of Tables ................................................................................................................... viii List of Figures ..................................................................................................................... x List of Appendices ............................................................................................................. xi Chapter 1 ............................................................................................................................. 1 1 Introduction .................................................................................................................... 1 Chapter 2 ............................................................................................................................. 3 2 Literature review, rationale and objectives .................................................................... 3 2.1 Violence in substance use disorder treatment population ....................................... 3 2.2 Consequences of violence ..................................................................................... 12 2.3 Correlates of violence ........................................................................................... 13 2.3.1 Primary explanatory variables .................................................................. 13 2.3.2 Control variables ....................................................................................... 19 2.4 Sex differences in correlates of violence .............................................................. 26 2.5 Limitations of existing research ............................................................................ 27 2.6 Thesis rationale ..................................................................................................... 30 2.7 Thesis objectives ................................................................................................... 31 Chapter 3 ........................................................................................................................... 33 3 Methods ........................................................................................................................ 33 3.1 Participants ............................................................................................................ 33 3.2 Exclusion criteria .................................................................................................. 34 v 3.3 Data collection procedures .................................................................................... 34 3.4 Questionnaire ........................................................................................................ 35 3.5 Incentives .............................................................................................................. 36 3.6 Response rate ........................................................................................................ 36 3.7 Measures ............................................................................................................... 36 3.7.1 Outcome variable ...................................................................................... 36 3.7.2 Primary explanatory variables .................................................................. 37 3.7.3 Control variables ....................................................................................... 41 3.8 Ethics approval...................................................................................................... 44 3.9 Statistical analyses ................................................................................................ 44 3.10 Analytic strategy ................................................................................................... 44 3.10.1 Modified Poisson regression ..................................................................... 44 3.10.2 Logistic regression .................................................................................... 45 3.11 Preliminary analyses ............................................................................................. 46 3.12 Analyses per study objectives ............................................................................... 46 3.13 Data management and final sample size ............................................................... 49 Chapter 4 ........................................................................................................................... 50 4 Results .......................................................................................................................... 50 4.1 Extent of missingness ........................................................................................... 51 4.2 Sample characteristics ........................................................................................... 53 4.3 Association among study variables ....................................................................... 57 4.3.1 Total sample .............................................................................................. 57 4.3.2 Males ......................................................................................................... 57 4.3.3 Females ..................................................................................................... 58 4.4 Analyses per study objectives ............................................................................... 65 4.5 Sensitivity analysis................................................................................................ 85 vi Chapter 5 ........................................................................................................................... 86 5 Discussion .................................................................................................................... 86 5.1 Consideration of findings ...................................................................................... 87 5.1.1 Extent of violence ..................................................................................... 87 5.1.2 Factors associated with violence ............................................................... 88 5.1.3 Sex differences in correlates of violence .................................................. 92 5.2 Clinical implications ............................................................................................. 99 5.3 Study strengths .................................................................................................... 100 5.4 Study limitations ................................................................................................. 101 5.5 Recommendations for future research ................................................................ 105 References ....................................................................................................................... 107 Appendices ...................................................................................................................... 116 Curriculum Vitae ............................................................................................................ 128 vii List of Tables Table 1. Results of studies reporting proportions of any violence in substance use disorder treatment clients ........................................................................................................................ 5 Table 2. Results of studies reporting proportions of violence in substance use disorder treatment clients by violence typologies ................................................................................... 6 Table 3. The relationship of licit and illicit substances to violence ........................................ 20 Table 4. Missingness on study variables of interest for treatment clients with valid outcome data by total sample, males and females ................................................................................. 52 Table 5. Characteristics of total sample, males and females by study variables of interest ... 55 Table 6. Correlation matrix of continuous study variables of interest for total sample (N = 403) ......................................................................................................................................... 60 Table 7. Correlation matrix of continuous study variables of interest for males (N = 195) and females (N = 207) ................................................................................................................... 61 Table 8. Associations between continuous and ordinal study variables of interest for total sample, males and females ...................................................................................................... 62 Table 9. Associations between continuous and categorical study variables of interest for total sample, males and females ...................................................................................................... 63 Table 10. Characteristics of treatment clients associated with violence during the past 12 months by total sample ........................................................................................................... 67 Table 11. Characteristics of treatment clients associated with violence during the past 12 months by males and females ................................................................................................. 68 Table 12. Unadjusted relative risks of violence during the past 12 months associated with demographics, drug consumption measures, personality traits and mental health indicators by total sample ............................................................................................................................. 71 viii Table 13. Unadjusted relative risks of violence during the past 12 months associated with demographics, drug consumption measures, personality traits and mental health indicators by males and females ................................................................................................................... 72 Table 14. Results from logistic regression with backward elimination procedures examining the associations between each of personality traits and mental health indicators and violence during the past 12 months while controlling for demographics and drug consumption measures by total sample ........................................................................................................ 76 Table 15. Results from logistic regression with backward elimination procedures examining the associations between each of personality traits and mental health indicators and violence during the past 12 months while controlling for demographics and drug consumption measures by males and females .............................................................................................. 77 Table 16. Adjusted relative risks of violence during past 12 months associated with personality traits and mental health indicators while controlling for demographics and drug consumption measures by total sample................................................................................... 79 Table 17. Adjusted relative risks of violence during past 12 months associated with personality traits and mental health indicators while controlling for demographics and drug consumption measures by males and females ........................................................................ 80 Table 18. Results from logistic regression with backward elimination procedures assessing multiplicative sex interactions between each of demographics, drug consumption measures, personality traits and mental health indicators and violence during the past 12 months ........ 83 ix
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