V Veterinary A Veterinary Laser Surgery e P t A PRACTICAL GUIDE R e A r Surgical and therapeutic use of lasers began in human Noel Berger, DVM, MS, Dip C i Laser Surgery n medicine in the early 1960s. Technology and equipment ABLS, Master Fellow VSLS, T a advanced rapidly. Over the last ten years veterinarians Boston Road Animal Clinic, IC Massachusetts, is a respected r have been exploring the many potential advantages that A y luminary in laser medicine and various lasers provide to their patients. Because laser L surgery. He is a published writer L light energy can be applied directly to target tissue or on the subject of laser surgery G a administered to distant lesions at a remote site through techniques in veterinary medicine U s fiberoptic components, laser surgery has become an and is Past President of the invaluable and growing veterinary surgical resource. Veterinary Surgical Laser Society ID e Unlike many medical technologies, the size, reliability, and a practicing companion E r A PRACTICAL GUIDE and portability of lasers have improved so rapidly that animal veterinarian. S they are now both economically and practically feasible u Peter H. Eeg, DVM, BSc, for the general and specialty veterinarian. Routine laser Master Fellow VSLS, Poolesville r use in veterinary medicine stands poised to gain large- Veterinary Clinic, LLC, Maryland, g scale general acceptance for everyday routine and has lectured nationally and e specialty procedures. internationally on surgical laser r techniques and is a published y Written by experts in the field, Veterinary Laser Surgery: writer on the subject of the use of A Practical Guide strives to help general and specialty laser energy in general veterinary veterinary practitioners understand, implement, and practice. He is a Past President expand the use of laser energy in safe and rational ways of the Veterinary Surgical Laser N Society and the current Executive for both surgical and therapeutic procedures to further o Vice President of the Veterinary improve each veterinarian’s ability to enhance their e Surgical Laser Society and a patient’s quality of life. l practicing companion animal B veterinarian. • PRACTICAL PICTORIAL GUIDE / ATLAS feature that e includes 31 case studies of the most common laser r surgery procedures. Broad spectrum of specific g laser information, including chapters covering e basic laser physics through specific laser surgery r , techniques and pain management. P • Special sections on CO2 and Diode laser wavelengths. e t • Provides veterinarians with skills and techniques to e improve the comfort and quality of patients’ lives r through appropriate laser use. H • User-friendly format makes referencing easy. . E • A practical reference for specialty and e general veterinarians. g Noel Berger, Peter H. Eeg Veterinary Laser Surgery A Practical Guide Veterinary Laser Surgery A Practical Guide Noel Berger DVM, MS, DABLS President, ex officio, Fellow Veterinary Surgical Laser Society, LTD Boston Road Animal Clinic, Inc. Sutton, Massachusetts Peter H. Eeg BS, DVM Executive Vice President Veterinary Surgical Laser Society, LTD Director of Small Animal Services and Laser Medicine Poolesville Veterinary Clinic Poolesville, Maryland © 2006 Blackwell Publishing First edition, 2006 All rights reserved Library of Congress Cataloging-in-Publication Data available Blackwell Publishing Professional upon request. 2121 State Avenue, Ames, Iowa 50014, USA The last digit is the print number: 9 8 7 6 5 4 3 2 1 Orders: 1-800-862-6657 Office: 1-515-292-0140 Fax: 1-515-292-3348 Web site: www.blackwellprofessional.com Blackwell Publishing Ltd 9600 Garsington Road, Oxford OX4 2DQ, UK Tel.: +44 (0)1865 776868 Blackwell Publishing Asia 550 Swanston Street, Carlton, Victoria 3053, Australia Tel.: +61 (0)3 8359 1011 Authorization to photocopy items for internal or personal use, or the internal or personal use of specific clients, is granted by Blackwell Publishing, provided that the base fee of $.10 per copy is paid directly to the Copyright Clearance Center, 222 Rosewood Drive, Danvers, MA 01923. For those organizations that have been granted a photocopy license by CCC, a separate system of payments has been arranged. The fee codes for users of the Transactional Reporting Service are ISBN-13: 978-0-8138- 0678-5; ISBN-10: 0-8138-0678-X/2006 $.10. Original Graphic Art by Bob Feaster Portions of Chapter 3 originally appeared in Laser Surgery in Gynecology: A Clinical Guide, (c)1993 Elsevier Inc. Reprinted with permission from Elsevier. To our families and colleagues We strive to improve quality of life every day. Contents Foreword ix Preface xi Acknowledgments xiii Part I Theory of Laser Surgery 1 01 General Principles of Laser Energy and Biophysics 3 02 Power Density and the Basic Effects of Radiant 19 Energy on Tissue 03 Fundamentals of Laser-Tissue Interactions 29 04 Types of Laser-Tissue Interaction Related to the 43 Rate of Heat Transfer Through Soft Tissue 05 Laser Systems, Wavelengths, and Technology Selection 63 Part II Practical Laser Surgery 77 06 Safety Considerations 79 07 Economic Considerations for Use of Laser Energy 91 in Veterinary Medical Practice 08 Pain Management Considerations for Laser Surgery 101 Procedures Part III Clinical Laser Technique and Procedures 109 09 Diode Lasers in Small Animal Veterinary Medicine 111 10 Introduction to Clinical Applications of CO Laser 139 2 Energy in Veterinary Medical and Surgical Services Case Studies 183 Suggested Reading 225 Index 227 vii Foreword Albert Einstein first described the concept of laser as an acronym forLight Amplification by Stimulated Emission of Radiation in 1917. It took more than forty years to pass before Theodore Maiman created the first laser, which was initially applied to surgical use. Since that time, lasers in medi- cine and surgery have widely expanded our abilities to more effectively fight disease and greatly improved our patient outcomes and comfort. Laser techniques in oncologic surgery have become effective alterna- tives to radical tumor resection and to palliative tumor treatment meth- ods.1 CO and Nd:YAG laser excision has been shown to provide almost 2 a 50% improvement in the control of local disease in-vivo compared with scalpel resection in rodent mammary gland tumors and human oral mu- cosal lesions.2,3 Lasers provide light with the necessary wavelength at the intensity sufficient for photodynamic therapy (PDT) for treating cancer- ous and non-cancerous lesions.4,5 Specific laser wavelengths can be cou- pled to flexible fiber optics, which provides the possibility of improved surgical access via endoscopy, allowing for minimally invasive procedures and enhanced patient outcomes in the areas of upper respiratory, optic, gastrointestinal, genitourinary, and neurological surgery. Despite the incredible development and advances that lasers have un- dergone in human surgical and therapeutic applications, lasers in veteri- nary practice have long been regarded as “surgical toys,” given their ex- pense and cumbersome size which made them impractical for private practice. In the past decade, however, technological breakthroughs have resulted in compact, portable, and reliable lasers that are economically feasible for both the general and specialty veterinary hospital. Laser use in clinical veterinary practice has become the newest “tool” for improved patient care and wider therapeutic options, but also poses additional health and safety hazards for the veterinary staff. An understanding of laser light properties and interaction with tissue will result in optimal patient outcomes without increased risk to the sur- geon, staff, or pet. For veterinarians to fully appreciate the advantages of laser energy, they must first understand how laser energy interacts with and affects living tissues before recommending or attempting to apply this technology to companion animals. The human literature has demon- strated these beneficial effects in lab animal studies and human clinical tri- als. These studies support the use of laser energy for the enhancement of quality of life and control of disease in the veterinary patient. They also provide a foundation for the commonly accepted laser surgical techniques and procedures which are constantly being implemented and refined in thousands of private veterinary practices around the world. Our pets can finally benefit from the very technology for which many research animals were used to perfect these laser surgical procedures on people. This book ix Foreword serves as a practical guide to the general and specialty veterinarian to un- derstand and use laser energy in a safe and rational fashion to enhance our patients’ quality of life and our overall standard of care. Barbara R. Gores, DVM Diplomate, American College of Veterinary Surgeons Veterinary Specialty Center of Tucson 4909 N. La Canada Drive Tucson, AZ 85704-1507 520-795-9955 [email protected] Notes 1. Paiva, M.B. et al. Nd:YAG Laser therapy for palliation of recurrent squamous cell carcinomas in the oral cavity. Lasers Surg Med 2002;31:64-69. 2. White, J.M., et al. Nd:YAG and CO laser therapy of oral mucosal lesions. J Clin 2 Laser Med Surg 1998;16:299-304. 3. Maker, V.K.; Elseth, K.M.; and Radosevich, J.A. Reduced in-vivo local recurrence with contact neodymium:yttrium-aluminum garnet (Nd:YAG) laser scalpels. Lasers Surg Med 1995;111:290-298. 4. McCaw, D. Photodynamic Therapy Can Successfully Treat Tumors. Vet Pract News 2001; 23. 5. Lucroy, M.D. Photodynamic therapy for companion animals with cancer. Vet Clin Small Anim 32 (2002) 693-702. x Preface Laser light is a unique, extremely powerful, and very selective form of en- ergy with the unparalleled ability to do beneficial work on living tissue. How it interacts with and changes living tissue is the central point to which many specialties strive to understand laser energy. For any veteri- narian to have a full appreciation of the power that laser energy can have on their patients’ quality of life, they must first understand the many physical and technical nuances that interrelate to provide this energy form. Laser energy can be applied directly to target tissue or administered to distant lesions at a remote site through fiber optic components. Each wavelength of laser energy has its own specific interaction with target tis- sues. Veterinary clinicians must fully appreciate the variation in tissue in- teraction by specific laser energy wavelengths before attempting to apply this technology to their patients. Surgical and therapeutic use of lasers began in human medicine in the early 1960s. Unlike many technologies, the size, reliability, and portabil- ity of laser units has improved so rapidly that they are both economically and practically feasible for the general and specialty veterinarian. The growth of laser use in veterinary medicine has progressed in the op- posite fashion to standard-held dogma of university implementation and general acceptance first, followed by private practitioners’ usage and ac- ceptance. The ease of implementation and laser company tutorial courses have spawned a private general clinical usage and experimentation with- out great oversight from traditional educators. Only now are universities, at the request of laser companies and practicing veterinarians, securing and implementing lasers in their clinical protocols. It will still be some years before extended study and research into specific uses of laser energy already accepted by practicing veterinary clinicians will be verified in the traditional university study fashion. Anecdotally accepted techniques and procedures being refined and implemented in thousands of private veteri- nary practices in the United States and around the world will support the use of this type of energy system for enhancement of patient quality of life and relief of animal disease and suffering. This book strives to help general and specialty veterinary practitioners both understand and implement the use of laser energy in a safe and ra- tional fashion for the improvement of patient quality of life. xi Acknowledgments My first professional responsibility is always to focus on the welfare of my patients. When I first began experimenting with surgical lasers in 1996 I felt alone and in front of the pack with no one to guide me through the process. Fortunately, in a very short period of time, I was able to suc- cessfully perform surgical procedures for my patients more favorably. Immediately, my excitement grew and I felt driven to share my knowledge and experience with my colleagues. It was imperative that the veterinary profession should know what worked and what didn’t. Seemingly invin- cible with lasers, I began using the tool for just about everything that I could do with a surgical blade or scissors. It was good, very good. My sur- gical cases were turning out better than ever before. I was able to ap- proach surgical problems in an entirely different light! Now, I felt as though more complicated surgical cases were well within my abilities, and certainly after performing them successfully, my practice grew. From an economic perspective, this has been one of the most exciting additions to my career. Laser surgery has allowed me to add more serv- ices that my practice can offer. My staff feels like they are special because they are part of a laser surgical facility, and they got to play with a lot of toys like video equipment and digital imagery as well as the laser and safety devices. Referrals from other veterinarians are common, and my ca- reer satisfaction has soared because I can help more patients, and I believe that I help them better. This book is the result of many years of good experiences with lasers in surgery. My outpouring is the result of support from many friends and family. The desire I have is for every veterinary practitioner to be comfort- able and competent in laser surgery. Hopefully this labor will help inspire you. There has been much effort by many to produce this work, and I wish to thank my lovely wife, Gayle, for giving me the freedom to learn and to teach. Also my three children Grace-Ann, Benton, and Samantha for never saying, “Daddy I miss you, please don’t go,” when I had to leave town to lecture or lead a wet lab. Also, my staff of laser technicians, es- pecially James Koproski and Erik Bishop, for getting just the right shot when we needed to take a picture during a surgical procedure. Good Lord, thank you for giving me this life to share with others. Noel Berger DVM, MS, DABLS * * * In preparing and compiling this book, I relied on my clinical experi- ences and independent research to gain an appropriate working laser pro- gram for my patients, clients, and clinical practice. I greatly appreciate the xiii