University of Otago, Christchurch

112 Pages·2013·2.65 MB·English

University of Otago, Christchurch
www.otago.ac.nz/christchurch/research/researchoffice/

2012 / 2013
Summer Studentship Programme
Lay Reports
COVER: Nicole Sycamore (student) with Tim Edmonds (Cure Kids Research & Innovation Manager) and
Stephanie Moor (supervisor)
Contents
1. Introduction 4
2. Sponsors 6
3. Supervisors 8
4. Summer Studentship Reports 10
Georgina Allison 10
The efficacy of home based non-invasive mechanical ventilation in patients with obesity hypoventilation syndrome
Jayden Ball 12
Validation of Smoking Cessation Advice Recorded in Hospital Discharge Summaries
Angela Ballinger 13
Calcimimetic agents to improve clinical outcomes in people with chronic kidney disease: Meta-analysis of randomised,
controlled trials
Annelise Basevi 14
Improving our clinical systems and care to help our patients have a better experience
David Bellamy 15
Betaine and secondary events in an acute coronary syndrome cohort: 4 year follow up
Heidi Blackburne 17
Quantifying the surgical impact factor in colorectal surgery: A pilot study
Chris Bloomer 19
Analyses of the pre and post arthroplasty Oxford 12 outcome scores in patients undergoing hip and knee replacement
Jonathan Bong 21
Measurement and motion analysis of knee function in patients following anterior cruciate ligament (ACL) injury
Melissa Butt 22
Dietary betaine and choline intakes in patients with type 2 diabetes participating in a weight loss study
Matthew Chamberlain 24
Psychological impact of September 2010 and subsequent earthquakes on Christchurch general practice patients
Thomas Chima 25
Randomised controlled trial of a consultation-based decision aid for hip fracture prevention
Shona Cole 26
Reduced intensity conditioned allogeneic haematopoietic stem cell transplantation at Christchurch Hospital - the first 12
years
Nicole Coman-Wright 28
Long term urate lowering - how sustained is it after discharge from a clinical trial?
Tom Currie 29
Factors predicting successful treatment of Perianal Crohn's Disease with anti-TNF alpha therapy
Lydia Dockrill 30
The use of supplementary oxygen therapy in the acute hospital setting
Josie Ganly 32
Does identification with the therapy model reduce dropout in psychotherapy for depression?
Ian Glass 34
Gating of physiological monitors in MARS scanner for small animal research
Kyle Grabowski 35
Measuring 5 year wear rates in total hip joint replacement patients receiving a new low wear (X3) polymer

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2012/2013 Summer Studentship Programme Lay Reports
(Margaret) Qiao He 37
Tolerability and efficacy of Rosuvastatin in a Lipid Clinic Outpatient Cohort
Karen Hodge 39
3D printing of porous scaffolds for tissue engineering
Simon Hogg 41
A 3D cell culture in a 96-well format for rapid drug screening in advanced ovarian cancer
Hannah Janssens 43
Blood flow correlates of cognitive impairments in Parkinson's disease
Thomas Judd 45
Bony marker identification and mapping in rat skulls for MARS neurogenesis
Gabrielle Kemp 46
The epidemiology of inflammatory bowel diseases in Nelson, New Zealand - Project 1
Latitia Kench 48
Optimising drug delivery during recovery from anaesthesia
Isabel Lee 49
Diabetic foot ulcers, investigating the impact that peripheral arterial disease, peripheral neuropathy and infection have on
healing time
Gemma Lilly 51
Cardiovascular Risk and Cognitive Function in CHALICE
Michelle Lindsay 52
Endometrial Cancer outcomes and follow up
Rachel Lines 54
Outcomes of patients returned to GP coordinated care after assessment via the Sleep Disorders Clinical Pathway
Thomas Loan 56
Development of the molecular detection of chromosomal and genetic abnormalities using BACs on Beads (Bobs) and
molecular karyotyping
Annabel Ludeke 57
Health literacy in general practice: describing practice nurses' understanding of health literacy
Campbell MacLachlan 59
Review of the Cancer Society Tissue Bank: 10 years of donations
Georgie Malcolm 61
Developing an evidence based pathway for UTI management in the primary/urgent care setting
Leila Marie 62
The effect of the Canterbury earthquakes on alcohol, substance and psychotropic medication use
Rachel McDonald 64
Christchurch Youth Hub Evaluation
Peter Meffan 66
The epidemiology of inflammatory bowel diseases in Nelson, New Zealand (Project 2)
Delwyn Munn 67
Vitamin C and cancer
Imogen Nolan 69
Biological variation of markers for multiple myeloma: What constitutes a significant change?
Lucy Peterson 70
Reducing barriers to practice nurse involvement in general cervical screening and understanding effective methods of inviting
and engaging priority women in cervical screening in general practice
Yousif Rassam 72
Pulmonary Arterial Hypertension – understanding our patient population. An audit of the Canterbury PAH clinic
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2012/2013 Summer Studentship Programme Lay Reports
Rachel Sanders 74
Substance abuse in pregnancy: Meconium analyses from infants born to a contemporary cohort of Canterbury women
Katie Sleeman 76
One size does not fit all in rehabilitation: What do Maori perceive as important during their inpatient journey?
Rebekah Smith 78
Thriving after trauma: a study of posttraumatic growth among Canterbury residents following the earthquake sequence since
September 2010
Leon Smyth 79
Cytochrome P450 CYP2C19 gene analysis and clopidogrel response in acute coronary syndromes
Nicole Sycamore 80
Assessment of the health utilisation of a group of high risk children to age 4 ½ years of age born to mothers on methadone
and a comparative control group
Harmony Thompson 82
Does early variation in sample separation time affect plasma glucose analysis? Implications for glucose meter evaluation
Alice Turner 84
Christchurch Breast Cancer Register: Management of Breast Cancer
Victoria Utley 86
A national audit of patients with Familial Adenomatous Polyposis (FAP) reviewing if international suggested surveillance is
occurring
Nancy Wang 88
Model-based therapeutics in ICU: Mechanical ventilation and the modern computer
Uddaka Wijesinghe 89
Does 1st trimester HbA1c influence fetal birth weight?
Max Wilkinson 91
Measuring plasma cytochrome c to assess mitochondrial damage
Tom Wilkinson 93
Five year follow up of conservatively managed women with CIN2 compared to women with CIN1
Annie Yau 95
Antipsychotics for older people in Canterbury: Understanding current prescribing practice
5. Photographs from the Presentations 97

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1. Introduction

Rau Rangatira ma, tena koutou, tena koutou, tena koutou katoa.
Nau mai haere mai Te Whare Wananga o Otago ki Otautahi. Piki mai kaki mai.

Each year the University of Otago, Christchurch (UOC) hosts a Summer Studentship Programme, allowing
participating students to get an introduction to research methods in a field of interest to them, such as public
health, clinical or laboratory-based research.

We had an impressive programme this year, in spite of the on-going challenges imposed by the closure of our
main building since the 2011 earthquakes, with 53 students assigned to a wide variety of health related
projects. This was only made possible through the continued efforts of our dedicated supervisors, the host
departments and our generous sponsors. We continue to be grateful for the assistance of organisations such
as Canterbury Scientific Ltd, the University of Canterbury and Lincoln University who provided laboratory
space for our researchers and their students.

This booklet is a compilation of the reports submitted by the student participants in the 2012/2013 Summer
Studentship Programme. The main objective of the Summer Studentship Programme is to give undergraduate
medical and health science students an introduction to research. It is a regional programme that encourages
participation from students and staff of the University of Otago, Christchurch; Canterbury District Health Board;
University of Canterbury and Lincoln University. Any student who is enrolled at a New Zealand tertiary academic
institution at a pre-doctoral level is eligible to apply for the studentships.

The summer studentship programme is heavily dependent on the financial generosity of external organisations
that contribute an educational grant for each student. We offer our thanks to these sponsors who are listed in
this report booklet. Thanks also to Carole Acheson, Professional Practice Fellow – Christchurch, for providing
the students with the seminar ‘Presentation Skills and Dealing with the Media’ and to Tuari Potiki, University of
Otago Director Maori Research Facilitation, for his introductions to the students’ presentations.

We are grateful to the following members of the Research Committee: Dr Gillian Abel, Professor Andrew Day,
Professor Lisa Stamp and Professor Martin Kennedy, who undertook the difficult tasks of assessing the project
applications and judging the students' presentations.

Three prizes of $500 each for outstanding studentship presentations were awarded and a fourth prize of $500
was awarded for the ‘Best Overall Project’ this year.
• Best oral presentation in the ‘Laboratory’ category – Simon Hogg, ‘A 3D cell culture in a 96-well format for
rapid drug screening in advanced ovarian cancer’. This prize was sponsored by Canterbury Scientific
Limited.
• Best oral presentation in the ‘Clinical’ category – Harmony Thompson, ‘Does early variation in sample
separation time affect plasma glucose analysis? Implications for glucose meter evaluation’. This prize
was sponsored by the Christchurch Radiology Group.
• Best oral presentation in the ‘Community’ category – Lucy Peterson, ‘Reducing barriers to practice nurse
involvement in general cervical screening and understanding effective methods of inviting and engaging
priority women in cervical screening in general practice’. This prize was sponsored by the Lions Club of
Selwyn.
• Best Overall Project – Angela Ballinger (student), Dr Suetonia Palmer (Supervisor), ‘Calcimimetic agents
to improve clinical outcomes in people with chronic kidney disease: Meta-analysis of randomised,
controlled trials’ This prize was sponsored by the Canterbury Branch Trust Board of the New Zealand
Federation of Graduate Women (Inc.).

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2012/2013 Summer Studentship Programme Lay Reports
Our particular thanks go to all of the organisations for their support of these prizes. We wish to offer our
congratulations to the winners and our thanks to all the students whose fine efforts made the selection process
such a difficult one.

These reports are a small reflection of the enormous amount of work and commitment put into the projects by
the students, staff, departments and sponsors. We hope that you will enjoy reading the reports and we look
forward to your support of the 2013/2014 Programme.

Professor Margreet Vissers Elizabeth Cunningham Virginia Irvine
Associate Dean (Research) Research Manager-Maori Research Manager

Research Office
Department of the Dean
University of Otago, Christchurch
PO Box 4345
Christchurch 8140
New Zealand

Telephone: [phone]
Email: [email protected]
Web: www.otago.ac.nz/christchurch/research/researchoffice/

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2012/2013 Summer Studentship Programme Lay Reports
2. Sponsors
• Age Concern Canterbury Trust
• Allied Health, Canterbury District Health Board
• Anaesthetists’ Instrument Pool Ltd
• Asthma Foundation
• Bone Marrow Cancer Research Trust
• Cancer Society of New Zealand, Canterbury/ West Coast Division
• Cancer Society Amberley Group
• Cancer Society Diamond Harbour Group
• Cancer Society Ellesmere Group
• Cancer Society Greymouth Group
• Cancer Society Hokitika Group
• Cancer Society Hurunui Group
• Cancer Society Rangiora Group
• Cancer Society Westport Group
• Canterbury Branch Trust Board of the New Zealand Federation of Graduate Women (Inc.)
• Canterbury District Health Board
• Canterbury Health Laboratories
• Canterbury Medical Research Foundation
• Canterbury Orthopaedic Services Trust
• Canterbury Scientific Ltd
• Christchurch Radiology Group Trust
• Cure Kids
• Don Beaven Summer Studentship
• Edith Tripp Trust Summer Studentship
• Guardian Trust / RG Bell Charitable Trust and the Diabetes Training & Research Trust
• Heart Foundation of New Zealand
• Helen Poole & Ian McDonald Memorial Summer Studentship
• Lions Club of Selwyn
• Maurice & Phyllis Paykel Trust
• Mr EG and Mrs DJ Drewitt, Ashburton, in Memory of Mary Terry
• Nelson Medical Research Trust
• New Zealand Breast Cancer Foundation
• Older Persons Health, Orthopaedics & Rehabilitation, Canterbury District Health Board
• Partnership Health Canterbury PHO
• Pegasus Health (Charitable) Ltd
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2012/2013 Summer Studentship Programme Lay Reports
• Planning & Funding, Canterbury District Health Board
• Rapaki Branch of Maori Women’s Welfare League
• The Canterbury Health Care of the Elderly Education Trust
• The Govan Family Summer Studentship
• The Royal New Zealand College of General Practitioners
• University of Otago Arthritis Research Theme
• University of Otago Health Sciences Divisional Summer Scholarships

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2012/2013 Summer Studentship Programme Lay Reports
3. Supervisors

Dr Gillian Abel Dr Michael Hlavac
Dr Paul Abernethy Professor Gary Hooper
Ms Cerina Altenburg Dr Ben Hudson
Dr Nigel Anderson Dr Ruth Hughes
Professor Tim Anderson Dr Jenny Jordan
Associate Professor Nicola Austin Mr Paul Kelly
Dr Sue Bagshaw Professor Martin Kennedy
Ms Karyn Balance Associate Professor Ross Kennedy
Associate Professor Lutz Beckert Associate Professor Peter Larson
Dr Caroline Bell Dr Michael Lever
Dr Juliet Berkeley Ms Ramai Lord
Professor Stephen Brennan Dr Helen Lunt
Dr Kim Burgess Dr Michael MacAskill
Dr Andrew Butler Associate Professor Dee Mangin
Dr Anthony Butler Ms Pip Mason
Dr Janet Carter Mr Christopher McEntyre
Professor Steven Chambers Dr Virginia McIntosh
Dr Peter Chapman Dr Tracy Melzer
Professor J G Chase Mr Grant Moore
Dr Kenny Chitcholtan Dr Stephanie Moor
Dr Lynley Cook Ms Helen Morrin
Ms Jackie Cooper Dr Hilda Mulligan
Dr Matthew Croucher Ms Olivia Paku
Dr Gabi Dachs Dr Suetonia Palmer
Ms Vivien Daley Ms Leigh Parsons
Ms Val Davey Ms Maria Pasene
Professor Andrew Day Ms Sally Powell
Dr Birgit Dijkstra Mr Jonathan Reid
Dr Kit Doudney Dr Bronwen Rhodes
Mr Tim Eglinton Professor Mark Richards
Dr Jane Elmslie Dr Andrew Richardson
Dr Michael Epton Professor Bridget Robinson
Professor John Evans Professor Alastair Rothwell
Associate Professor Chris Florkowski Ms Jo Sanders
Professor Chris Frampton Dr Ruth Savage
Dr Darryl Fry Professor Philip Schluter
Dr Peter Ganly Dr Ria Schroder
Dr Ashley Garrill Mr Ben Schon
Associate Professor Richard Gearry Professor Russell Scott
Dr Susan Gee Dr Elango Selvarajah
Professor Peter George Dr Geoffrey Shaw
Dr Shayne Gooch Dr Bryony Simcock
Dr Matthew Grayling Dr Sandy Slow
Dr Jo Gullam Dr Debbie Snell
Dr Gavin Harris Dr Ruth Spearing
Mr Charles Hawes Ms Carole Spencer
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2012/2013 Summer Studentship Programme Lay Reports