Underlying Factors Leading To Autism - Dr Amy Yasko

295 Pages·2007·25.97 MB·English

by  Amy Yasko

A Molecular Approach to Health Care
Underlying Factors Leading
to Autism
Dr. Amy Yasko
“What do schizophrenia, diabetes and autism have in
common? The answer is that many different factors act
together to influence their development. As well as
fundamentals like age and gender, other genetic and
environmental factors…may play a role in the onset of
multifactorial diseases.
these so-called ”
Multifactorial Diseases:Choose your targets
BIOPEOPLE, Summer 2004

Predisposing Factors That Increase
Susceptibility to Autism
Methylation Cycle Mutations
Increased Glutamate Receptors (total “Excitotoxin” level)
Chronic Bacterial Infection
Chronic Viral Infection
Heavy Metal Burden
HLA Type
Relationship to Asthma
DPT Vaccine
Predisposing Factors That Increase
Susceptibility to Autism
• Methylation Cycle Mutations •
Increased Glutamate Receptors (total “Excitotoxin” level)
Chronic Bacterial Infection
Chronic Viral Infection
Heavy Metal Burden
HLA Type
Relationship to Asthma
DPT Vaccine
What is
Methylation?
Methylation
CH3
Methyl groups –
H
C
H
H
Bound to DNA, enzymes, vitamins
In many cancer cells, inappropriate methylation
– the attachment of methyl (CH ) groups to
3
DNA’s cytosine bases – can silence genes that
suppress tumor growth.
The Importance of
Methylation