Table Of Content

Contents Foreword Image contrast in high-resolution electron microscopy of biological macromolecules: TMV in ice R. Henderson Electron cryomicroscopy of frozen-hydrated biological specimens: analysis of freezing artifacts by X-ray cryocrystallography J. Lepault, J.-L. Ranck and I. Erk Desired features of a cryoelectron microscope for the electron crystallography of biological material F. Zemlin Specimen flatness of thin crystalline arrays: influence of the substrate R.M. Glaeser 2D crystallization: from art to science B.K. Jap, M. Zulauf, T. Scheybani, A. Hefti, W. Baumeister, U. Aebi and A. Engel Has negative staining still a place in biomacromolecular electron microscopy? A. Bremer, C. Henn, A. Engel, W. Baumeister and U. Aebi Metal decoration of biomacromolecules and molecular assemblies: a review S. Weinkauf and L. Bachmann Site-specific cluster labels J.F. Hainfeld A brief look at imaging and contrast transfer R.H. Wade Image restoration for biological objects using external TEM control and electronic image recording D. Typke, R. Hegerl and J. Kleinz Contents Magnification mismatches between micrographs: corrective procedures and implications for structural analysis A. Aldroubi, B.L. Trus, M. Unser, F.P. Booy and A.C. Steven Overview of computer-aided electron microscopy K.H. Downing, A.J. Koster and D. Typke Automatic focus correction for spot-scan imaging of tilted specimens K.H. Downing Automated microscopy for electron tomography A.J. Koster, H. Chen, J.W. Sedat and D.A. Agard Computer-controlled spot-scan imaging of crotoxin complex crystals with 400 keV electrons at near-atomic resolution J. Brink, W. Chiu and M. Dougherty Three-dimensional reconstruction of single particles negatively stained or in vitreous ice J. Frank and M. Radermacher Processing images of helical structures: a new twist D.G. Morgan and D. DeRosier From lattice distortion to molecular distortion: characterising and exploiting crystal deformation W.O. Saxton, R. Diirr and W. Baumeister Correlation functions revisited M. van Heel, M. Schatz and E. Orlova Factors influencing the precision of quantitative scanning transmission electron microscopy S.A. Miiller, K.N. Goldie, R. Biirki, R. Haring and A. Engel Combination of EELS modes and electron spectroscopic imaging and diffraction in an energy-filtering electron microscope L. Reimer, I. Fromm, P. Hirsch, U. Plate and R. Rennekamp Quantitative energy-filtered electron microscopy of biological molecules in ice J.P. Langmore and M.F. Smith Quantitative scanning tunneling microscopy and scanning force microscopy of organic materials H.-J. Butt, R. Guckenberger and J.P. Rabe Contents Performance of a low-noise CCD camera adapted to a transmission electron microscope S. Kujawa and D. Krahl The photographic emulsion as analog recorder for electrons E. Zeitler A brief survey of software packages for image processing in biological electron microscopy R. Hegerl Author index Subject index