Tumors of the Liver PDF
Preview Tumors of the Liver
Recent Results in Cancer Research Fortschritte der Krebsforschung Progres dans Ies recherches sur Ie cancer 26 Edited by V. G. Allfrey, New York . M. Allgower, Basel· K. H. Bauer, Heidelberg I. Berenblum, Rehovoth . F. Bergel, Jersey . J. Bernard, Paris . W. Bern hard, Villejuif . N. N. Blokhin, Moskva· H. E. Bock, Tubingen . P. Bucalossi, Milano· A. V. Chaklin, Moskva· M. Chorazy, Gliwice . G. J. Cunningham, Richmond· W. Dameshek t, Boston· M. Dargent, Lyon· G. Della Porta, Milano· P. Denoix, Villejuif . R. Dulbecco, La Jolla· H. Eagle, New York R. Eker, Oslo· P. Grabar, Paris· H. Hamperl, Bonn· R. J. C. Harris, London E. Hecker, Heidelberg . R. Herbeuval, Nancy . J. Higginson, Lyon w. C. Hueper, Fort Myers· H. lsliker, Lausanne· D. A. Karnofsky t, New York . J. Kieler, Kobenhavn . G. Klein, Stockholm . H. Koprowski, Phil adelphia . L. G. Koss, New York . G. Martz, Zurich . G. Mathe, Villejuif O. Muhlbock, Amsterdam· W. Nakahara, Tokyo . V. R. Potter, Madison A. B. Sabin, Rehovoth . L. Sachs, Rehovoth . E. A. Saxen, Helsinki W. Szybalski, Madison· H. Tagnon, Bruxelles . R. M. Taylor, Toronto A. Tissieres, Geneve . E. Uehlinger, Zurich . R. W. Wissler, Chicago T. Yoshida, Tokyo Editor in chief P. Rentchnick, Geneve Springer-Verlag New York. Heidelberg. Berlin 1970 Prometheus Bound. Painted by Peter Paul Rubens, Flemish, 1611-1612; vulture painted by Frans Snyders, also Flemish. Legend: The fable relates that Prometheus stole a bit of fire from the sun and gave it to the human race. Jupiter (Saturn), in his anger and jealousy at this presumption, had Prometheus chained on the mountain top, where the vulture (golden eagle) atc his liver away during the day. According to the story, the liver regenerated during the night. How the original mythologist knew that the liver has an irresistible impulse to regenerate itself remains a mystery. (Courtesy of Phila delphia Museum of Art, Wilstach Collection). Pertaining to the contribution by Prof. BENGMARK "Liver Regeneration" Tumors of the Liver Editors George T. Pack· Abdol H. Islami With 177 Figures Springer-Verlag New York· Heidelberg. Berlin 1970 Sponsored by the Swiss League against Cancer ISBN 978-3-642-48732-3 ISBN 978-3-642-48730-9 (eBook) DOI 10.1007/918-3-642-48730-9 This work is subject to copyright. All rights are reserved, whether the whole or part of the material is concerned, specifically those of translation, reprinting, re-use of illustrations, broadcasting, reproduction by photocopying machine or similar means, and storage in data banks. Under § 54 of the German Copyright Law where copies are made for other than private use, a fee is payable to the publisher, the amount of the fee to be determined by agreement with the publisher. © by Springer-Verlag Berlin' Heidelberg 1970. Library of Congress Catalog Card Number 71-99868. Softcover reprint of the hardcover 1st edition 1970 The use of general descriptive names, trade names, trade marks, etc. in this publication, even if the former are not especially identified, is not to be taken as a sign that such names, as understood by the Trade Marks and Merchandise Marks Act, may accordingly be used freely by anyone. Title No. 3641 To Dr. George T. Pack The 1968 Distinguished Service Award of the American Society of Abdominal Surgeons was presented to Dr. GEORGE T. PACK in recognition of his outstanding achievements in surgery, research and medical education. Born in Antrim, Ohio in 1898, this dedicated surgeon earned his M.D. degree at Yale University, cum laude, in 1922; a Fellow at the Universite de Paris, Institute of Radium (Curie Foundation) in 1927, he won a Diploma in Reconstructive Surgery at the Hopitale de Paris in the same year. From 1928 to 1931, he was a Rockefeller Fellow and Resident Surgeon at the Memorial Cancer Center in New York City. The credentials in Dr. PACK'S impressive portfolio are too numerous to list in their entirety in a brief presentation such as this for Dr. PACK had dedicated his life to the science of medicine-as a practitioner, in the laboratory, and as a scholar-and was honored by a host of medical organizations throughout the world. His hospital and laboratory appointments included the following: Attending Surgeon at Memorial Hospital, New York City; Clinician at Sloan Kettering Insti tute for Cancer Research; Member of the Surgical Staff, Doctors Hospital, New York City; Consultant in Cancer, New York City Department of Health; Consul tant in Neoplastic Diseases, St. Clare's Hospital, New York City; and Special Con sultant, National Cancer Institute. Dr. PACK had been awarded Honorary Degrees by the University of Alabama; the College of Physicians and Surgeons, Costa Rica; University of Buenos Aires; Univer sity of Rio de Janeiro; University of Rio Grande do SuI, Brazil; University of Cara bobo, Venezuela and the University of Lisbon. He also held honorary professorships at the University of Chile, at the National University of Nicaragua and at the Uni versities of Guayaquil, Santo Domingo, Zulia in Maracaibo, Venezuela; and Cara bobo. A member of nearly one hundred medical and scientific societies here and abroad, Dr. PACK served as Chairman of the Committee on Cancer Therapy of the World Health Organization in 1965, and was a member of the Executive Committee of the American Cancer Society and Vice-President of the International Union Against Cancer. Among the numerous teaching and research appointments he held were: Profes sor of Pathology and Associate Dean, University of Alabama School of Medicine; Assistant Professor of Clinical Surgery, Yale University School of Medicine; Assistant Professor of Clinical Surgery, Cornell University Medical College; Clinical Professor of Surgery, New York Medical College. VIII To Dr. George T. Pack A holder of the National Order of Merit of Paraguay and the Salvation Star for Achievement of National Taiwan University (among 17 decorations and awards he had received since 1922), Dr. PACK served on the editorial boards of seven medical journals, and was Founder of the Pack Medical Group and Director of the Pack Medical Foundation, New York City. In 1967 he received the Special Citation Award of the American Cancer Society-to a "great physician, dedicated scholar, inspired teacher and international leader in the continuing advancement of his profession in the cause of cancer control". Contents Chapter 1 Introduction. By GEORGE T. PACK and ABDOL H. ISLAMI 1 Chapter 2 The Classification of Liver Tumors. By HERWIG HAMPERL. With 10 Figures 4 Chapter 3 The Pathologic Anatomy of Primary Hepatic Tumors. By GEORGE K. HIGGINS. With 6 Figures. 15 Chapter 4 The Epidemiology of Primary Carcinoma of the Liver. By JOHN HIGGINSON. With 7 Figures. 38 Chapter 5 Hepatic Carcinogenesis. By WALTER J. BURDETTE. With 28 Figures 53 Chapter 6 Metastatic Cancer to and from the Liver. By GEORGE T. PACK and ABDOL H. ISLAM!. With 5 Figures 72 Chapter 7 The Diagnosis of Tumors of the Liver. By DAVID W. Mo- LANDER and GEORGE T. PACK. With 4 Figures. 85 Chapter 8 Hepatic Photoscanning as an Aid in Determining Treat- ment Policies for Cancer Involving the Liver. By IRVING M. ARIEL, GEORGE T. PACK, and DAVID W. MOLANDER. With 18 Figures 95 Chapter 9 Surgical Anatomy of the Liver. By HANS ELIAS. With 24 Figures 116 Chapter 10 Surgical Anatomy of the Extrahepatic Biliary System. By PAUL J. MIRANTI and ABDOL H. ISLAMI. With 13 Figures 137 Chapter 11 Anesthesia for Hepatic Lobectomy. By OLGA SCHWEIZER. 162 Chapter 12 Surgical Treatment of Liver Tumors. By GEORGE T. PACK and ABDOL H. ISLAMI. With 13 Figures. 166 Chapter 13 Liver Regeneration. By STIG BENGMARK. With 13 Figures. 187 Chapter 14 Transplantation of the Liver. By MARSHALL J. ORLOFF, JAMES G. CHANDLER, and JAMES E. BERNSTEIN. With 14 Figures 213 Chapter 15 The Pathology of Tumors of the Liver in Infancy and Childhood. By ARCHIE H. BAGGENSTOSS. With 10 Figures. 240 Chapter 16 Metabolism Before and After Hepatic Lobectomy. By DAVID W. MOLANDER and GEORGE T. PACK. With 5 Figures 259 x Contents Chapter 17 Radiation Therapy of Tumors of the Liver. By RALPH F. PHILLIPS . 272 Chapter 18 Treatment of Inoperable Cancer of the Liver by Intra Arterial Radioactive Isotopes and Chemotherapy. By IRVING M. ARIEL and GEORGE T. PACK. With 5 Figures . 277 Chapter 19 End Results in the Surgical Treatment of Liver Tumors. By THEODORE R. MILLER 293 Subject Index. . 299 Contributing Authors IRVING M. ARIEL, M.D., F.A.C.S., Associate Clinical Professor of Surgery, New York Medical College; Chief, Soft Somatic Tissue Tumor Service, Hospital for Joint Diseases; Attending Surgeon, Pack Medical Group, New York, New York. ARCHIE H. BAGGENSTOSS, M.D., Professor of Pathology, Mayo Graduate School of Medicine (University of Minnesota); Senior Consultant, Section of Experimental and Anatomic Pathology, Mayo Clinic, Rochester, Minnesota. STIG BENGMARK, M.D., Associate Professor of Surgery, Department of Surgery II, University of G6teborg, G6teborg, Sweden. JAMES E. BERNSTEIN, M.D., Chief Resident, Department of Surgery, School of Medi cine, University of California, San Diego, La Jolla, California. WALTER J. BURDETTE, Ph.D., M.D., F.A.C.S., Professor of Surgery and Associate Director, The University of Texas M.D. Anderson Hospital and Tumor Institute, Houston, Texas. JAMES G. CHANDLER, M.D., Assistant Professor of Surgery, Department of Surgery, School of Medicine, University of California, San Diego, La Jolla, California. HANS ELIAS, Ph.D., Professor of Anatomy, The Chicago Medical School, Chicago, Illinois. HERWIG HAMPERL, M.D., Director, Emeritus, Pathological Institute, University of Bonn, Germany. GEORGE K. HIGGINS, M.D., Pathologist, Pack Medical Group and Equitable Life Assurance Society; Director of Laboratories, New York Eye and Ear Infirmary, New York, New York. JOHN HIGGINSON, M.D., M.R.C.P. (London), Director, International Agency for Research on Cancer, W.H.O. ABDOL H. ISLAMI, Ph.D., M.D., F.A.C.S., Attending Surgeon and Director of Depart ment of Medical Education, St. Barnabas Medical Center, Livingston, New Jersey; Assistant Clinical Professor of Surgery, New Jersey College of Medicine and Dentistry, Jersey City, New Jersey. THEODORE R. MILLER, M.D., F.A.C.S., Attending Surgeon, Pack Medical Group; Attending Surgeon, Memorial Hospital for Cancer and Allied Diseases; Clinical Associate Professor of Surgery, Cornell University Medical College, New York, New York. PAUL J. MIRANTI, M.D., F.A.C.S., Assistant Clinical Professor of Anatomy, New Jersey College of Medicine and Dentistry; Attending Surgeon, Jersey City Medical Center and Christ Hospital, Jersey City, New Jersey. DA VID W. MOLANDER, M.D., F.A.C.P., Assistant Attending Physician, Memorial Hospital for Cancer and Allied Diseases; Attending Physician, Pack Medical Group; Clinical Assistant Professor of Medicine, Cornell University Medical College, New York, New York.
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