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Transplantation and Blood Transfusion: Proceedings of the Eighth Annual Symposium on Blood Transfusion, Groningen 1983, organized by the Red Cross Blood Bank Groningen-Drenthe PDF

227 Pages·1984·20.39 MB·English
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Preview Transplantation and Blood Transfusion: Proceedings of the Eighth Annual Symposium on Blood Transfusion, Groningen 1983, organized by the Red Cross Blood Bank Groningen-Drenthe

TRANSPLANTATION AND BLOOD TRANSFUSION DEVELOPMENTS IN HEMATOLOGY AND IMMUNOLOGY Lijnen, H.R., Collen, D. and Verstraete, M., eds: Synthetic Substrates in Clinical Blood Coagulation Assays. 1980. ISBN 90-247-2409-0 Smit Sibinga, C. Th., Das, P.C. and Forfar, J .0., eds: Paediatrics and Blood Transfusion. 1982. ISBN 90-247-2619-0 Fabris, N., ed: Immunology and Ageing. 1982. ISBN 90-247-2640-9 Homstra, G.: Dietary Fats, Prostanoids and Arterial Thrombosis. 1982. ISBN 90-247-2667-0 Smit Sibinga, CTh., Das, P.C. and Loghem, van J.J., eds: Blood Transfusion and Prob lems of Bleeding. 1982. ISBN 90-247-3058-9 Dormandy, J., ed: Red Cell Deformability and Filterability. 1983. ISBN 0-89838-578-4 Smit Sibinga, C.Th., Das, P.C. and Taswell, H.F., eds: Quality Assurance in Blood Bank ing and Its Clinical Impact. 1984. ISBN 0-89838-618-7 Besselaar, A.M.H.P. van den, Gralnick, H.R. and Lewis, S.M., eds: Thromboplastin Calibration and Oral Anticoagulant Control. 1984. ISBN 0-89838-637-3. Fondu, P. and Thijs, 0., eds: Haemostatic Failure in Liver Disease. 1984. ISBN 0-89838-640-3 Smit Sibinga, C.Th., Das, P.C and Opelz, G., eds: Transplantation and Blood Transfu sion. 1984. ISBN 0-89838-686-1 Transplantation and Blood Transfusion Proceedings of the Eighth Annual Symposium on Blood Transfusion, Groningen 1983, organized by the Red Cross Blood Bank Groningen-Drenthe edited by C.TH. SMIT SIBINGA and P.C. DAS Red Cross Blood Bank Groningen-Drenthe The Netherlands G. OPELZ Ruprecht Karls University Heide/berg, FRG 1984 SPRINGER-SCIENCE+BUSINESS MEDIA, B.V. Library of Congress Cataloging in Publication Data ISBN 978-1-4613-3842-0 ISBN 978-1-4613-3840-6 (eBook) DOI 10.1007/978-1-4613-3840-6 Copyright © 1984 by Springer Science+Business Media Dordrecht Originally published by Martinus NijhoffPublishers, Boston in 1984 AII rights reserved. No part of this publication may be reproduced, stored in a retrieval system, or transmitted in any form or by any means, mechanical, photocopying, recording, or otherwise, without the prior written permission of the publishers, Springer-Science+Business Media, B.V. m TRAVENOl Acknowledgement This publication has been made possible through the support of Travenol, which is gratefully acknowledged. VII CONTENTS Invited speakers IX Foreword XI Opening address XIII 1. Principles in transplantation practice The development of the liver transplantation team in Groningen (C.H. Gips, R.A.F. Krom) 3 Aspects of grafting and rejection with special reference to the transplantation of lymphocytes (W.L. Ford) 9 The DRw6 phenomenon in renal transplantation (G. F.J. Hendriks) 17 Cryopreservation of platelets, bone marrow and lymphocytes: application for the transplant recipient (A.B. Glassman) 23 Discussion 35 II. Supportive hemotherapy Immune modulation aspects of blood transfusion in transplantation practice (G.G. Persijn) 43 Role of lymphocytes in graft-versus-host disease and its prevention (D. W. van Bekkum) 57 Selective decontamination of the digestive tract as a method of infection prevention in granulocytopenic patients; a follow-up study in 102 patients (H.G. de Vries-Hospers, D.Th. Sleijfer, N.H. Mulder, H.O. Nieweg, D. van der Waaij) 65 CMV infection and its prevention with specific immunoglobulins (W.G. Ho, D.J. Winston, R.E. Champlin, R.P. Gale) 73 Characterization of the new cytomygalovirus immunoglobulin preparation for intravenous use (R. Schweitzer) 79 The role of interferons in viral infections in immune compromised patients (R.T. Schooley, M.S. Hirsch, R.H. Rubin, K. Cantell) 83 VIII Fundamentals of platelet and granulocyte support in myelo suppressed leukemia and bone marrow transplant patients (J.P. Hester, R. Ayyar, M. Keating. K. Dicke) 91 The use of monoclonal antibodies in clinical transplantation (G. Opelz) 101 Discussion 111 III. Organ preservation Organization and effectiveness in donor procurement and transplantation (R.J. Ploeg) 123 Organization of a hospital bone marrow panel (D.C.O. James) 131 Developments and limitations in liver preservation (K. RoBes, R. Y. CaIne) 141 New developments in kidney preservation (G. Kootstra, B.G. Rijkmans, W.A. Buurman, Th.J.M. Ruers, J. P. van Hooff) 145 Preservation of hemopoietic stem cells (J.M. Goldman) 153 Is the basis of cleaning autologous bone marrow transplantation in leukemia strong enough? (B. LOwenberg) 161 Discussion 165 IV. Specific organ transplantation Kidney transplantation - Current perspective (R.F.M. Wood) 175 Present status of clinical liver transplantation based on a review of 5 centres: Pittsburgh. Cambridge, Hannover, Innsbruck and Groningen (R.A.F. Krom) 185 Allogeneic bone marrow transplantation (W.G. Ho, D.J. Winston, R.E. Champlin, S.A. Feig, R.P. Gale) 191 Autologous transplantation of blood derived hemopoietic stem cells (M. Korbling, Th.M. Fliedner) 199 The role of autologous bone marrow transplantation in cancer treatment (G.L. Phillips) 205 Evolution of superior immune suppression for heart and heart-lung transplantation (B.P. Griffith, R.L. Hardesty, A. Trento, Ann Lee, H.T. Bahnson) 217 Discussion 227 IX INVITED SPEAKERS D.W. van Bekkum - Radiological Institute TNO, Rijswijk, NL (modera tor) W.L. Ford - Dept. of Pathology, University of Manchester, UK C.H. Gips - Dept. of Internal Medicine, University of Gro ningen, Groningen, NL A • B. Glassman - Medical University of South Carolina, Charles (moderator) ton SC, USA J. M. Goldman - Royal Postgraduate Medical School, University of London, London, UK B. Griffith - Dept. of Surgery, University of Pittsburgh, Pittsburgh PA, USA G. F.J. Hendriks - Universital Hospital Leiden, Leiden, NL J.P. Hester - University of Texas System Cancer Center, Houston TX, USA W.G. Ho - UCLA Hospital & Clinics, Los Angeles CA, USA D.C.O. James - The Anthony Nolan Bone r-.!arrow Appeal, London, UK G. Kootstra - Dept. of General Surgery, University of Lim burg, Ivlaastricht, NL M. Korbling - Ruprecht-KarIs-University, Heidelberg, FRG (modera tor) R.A.F. Krom - Dept. of Surgery, University of Groningen, Groningen, NL B. Lowenberg - Dr. Daniel den Hoed Cancer Centre, Rotter (moderator) dam, NL G. Opelz - Ruprecht-Karls-University, Heidelberg, FRG (chairman) G. G. Persijn - Eurotransplant Foundation, University of Lei den, Leiden, N L G.L. Phillips - Barnard Cancer Center, Washington University, st. Louis MO, USA x R.J. Ploeg - Dept. of Surgery, University of Leiden, Lei den, NL K. RolIes - Dept. of Surgery, University of Cambridge Clinical School, Cambridge, UK R. T. Schooley - Harvard Medical School, Massachusetts General Hospital, Boston MA, USA H. G. de Vries-Hospers - Laboratory for Medical Microbiology, University of Groningen, Groningen, NL D. van der Waaij - Laboratory for Medical Microbiology, University (moderator) of Groningen, Groningen, NL J. van der Wijk - Dept. of Surgery, University of Groningen, (moderator) Groningen, NL R. Wood - Nuffield Dept. of Surgery, University of Oxford, Oxford, UK

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