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Transcript of “Dr. Daniel Amen: Alzheimer’s, Brain Food & SPECT Scans - #227” Bulletproof Radio podcast #227 © The Bulletproof Executive 2013 Bulletproof Toolbox Podcast #227, Dr. Daniel Amen Warning and Disclaimer The statements in this report have not been evaluated by the FDA (U.S. Food & Drug Administration). Information provided here and products sold on bulletproofexec.com and/or upgradedself.com and/or betterbabybook.com are not intended to diagnose, treat, cure, or prevent any disease. The information provided by these sites and/or by this report is not a substitute for a face-to-face consultation with your physician, and should not be construed as medical advice of any sort. It is a list of resources for further self-research and work with your physician. We certify that at least one statement on the above-mentioned web sites and/or in this report is wrong. By using any of this information, or reading it, you are accepting responsibility for your own health and health decisions and expressly release The Bulletproof Executive and its employees, partners, and vendors from from any and all liability whatsoever, including that arising from negligence. Do not run with scissors. Hot drinks may be hot and burn you.     If you do not agree to the above conditions, please do not read further and delete this document.   2 Bulletproof Toolbox Podcast #227, Dr. Daniel Amen     Dave:   Hi,  everyone.  It’s  Dave  Asprey  with  Bulletproof  Radio.  Today’s  cool  fact  of   the  day  is  that  if  you’re  someone  who  has  a  really  great  sense  of  direction   even  in  places  where  you’ve  only  been  once  before,  your  brain  maybe  a   little  bit  different.  It  turns  out  that  different  nerve  cells  in  your   hippocampus  are  activated  in  different  locations  so  your  brain  is  basically   drawing  maps  of  where  you  are  through  your  nerve  cells.       Those  grid  cells  function  as  your  brain’s  GPS.  They’re  impacted  when   someone  has  a  stroke  or  develops  Alzheimer's.  Today’s  guest,  it’s  a  great   honor  to  have  him  on,  is  widely  regarded  as  one  of  the  world’s  foremost   experts  in  using  brain  imaging  to  everyday  clinical  practice,  9  times  New   York  Times  bestselling  author,  founder  and  CEO  of  Amen  Clinics  and   someone  who  actually  is  responsible  for  me  being  a  biohacker  today.  I’m   talking  about  Dr.  Amen.  Dr.  Amen,  welcome  to  the  show.     Dr.  Amen:   Thanks,  Dave.  It’s  so  nice  to  be  with  you.     Dave:   Dr.  Amen,  the  reason  that  I  say  that  you’re  responsible  for  me  being  a   biohacker  today  is  that  more  than  a  dozen  years  ago,  I  read  your  very  first   New  York  Times  best  seller  and  I  said  this  is  interesting.  I  went  out  and  I   found  someone  who  trained  with  your  for  many  years.  I  ordered  a  SPECT   scan  which  is  the  type  of  brain  imaging  that  you’ve  used,  thousands  and   thousands  of  times  to  get  a  better  understanding  of  what’s  going  on  in  the   brain.       What  I  found  was  my  brain  was  in  bad  shape  but  it  meant  that  there  was   something  that  I  could  work  on.  Without  having  the  idea  that  says  look,  I   can  change  the  metabolism  also  change  the  function  of  my  brain.  I  would   have  just  felt  like  it’s  just  because  I’m  weak  or  because  I’m  not  trying  hard   enough  and  it  would  have  kept  doing  what  didn’t  work.  Having  a  picture  of   my  brain  really  did  change  my  brain  and  ultimately  changed  my  life  so  first,   thank  you.     Dr.  Amen:   You  are  welcome.     3 Bulletproof Toolbox Podcast #227, Dr. Daniel Amen Dave:   You’ve  also  been  a  speaker  at  the  Bulletproof  Conference  and  you’re   featured  in  Moldy,  the  documentary  that’s  coming  out  on  June  4th  which  is   really  exciting  because  you  talked  about  the  effects  specifically  of  toxins  on   the  brain  and  I  did  had  a  chance  to  do  a  follow  up  brain  scan  with  you  just   last  week.  It  was  down  in  your  offices.       I  was  really  pleased  that  my  brain  scan  looks  very  different  now  than  where   it  did  before.  When  I  had  my  first  scan  down,  I  didn’t  know  it  but  I  was   living  at  a  house  that  had  substantial  amounts  of  environmental  toxic   molds,  very  likely  stachybotrys  which  is  one  of  the  worst  ones.  Are  you  okay   with  mentioning  what  my  brain  looked  like?  I’m  okay  if  you  say  that  it   looked  beyond  a  description  that  it  looked  like  someone  who’d  been  using   some  sort  of  drugs  or  something.  Do  you  remember  what  you  were  saying   there?     Dr.  Amen:   I  do.  It  looked  toxic.  I  mean,  it’s  the  first  thing  I  saw  that  your  brain  had   really  low  activity  compared  to  a  healthy  brain  in  a  pattern  that  we  often   see  either  in  drug  addicts  or  people  who  are  exposed  to  environmental   toxins  or  people  who  have  an  infection.  I  mean  there  was  clearly  something   not  right  with  your  brain.       The  scans  always  teach  us  to  ask  better  questions  which  is  why  does  it  look   like  that.  If  you’re  telling  us  you’re  not  doing  drugs  and  your  wife  backs  that   up  because  sometimes  drug  addicts  lie,  then  we’ve  really  have  to  go  after   and  find  out  why  does  it  look  like  that.     Dave:   I  was  blown  away  because  no  one  has  ever  said  you  had  the  brain  of  a   heavy  drug  user  even  though  I  wasn’t  using  any  drugs  at  the  time.  With  the   thought  of  using  drugs  all  the  time  is  important  because  I  could  barely  keep   going.  When  I  had  that  scan  done  though,  I  was  getting  my  MBA  at   Wharton  while  working  full-­‐time  at  a  startup  that  ended  up  selling  for  a   value  of  around  $600  million.       I  was  successful  in  my  career  barely,  absolutely  not  successful  in  my   relationships  and  successful  in  school  barely.  When  I  saw  that  picture  at  the   time,  it  was  like,  “Great.  At  least  I  can  work  on  something.  Now,  I  know  that   4 Bulletproof Toolbox Podcast #227, Dr. Daniel Amen I  have  hope.”  To  hear  a  dozen  years  later,  your  take  on  that  is  like,  “You   look  like  you’re  a  heavy  duty  drug  user.”       My  whole  life  I  thought  it’s  just  because  I’m  weak.  It’s  because  I’m  not   trying  hard  enough.  I  was  putting  all  this  effort  that  was  to  fight  against  the   toxin  that  I  didn’t  see  that  was  in  the  walls  of  my  house  basically.  How   common  is  that?  How  often  do  you  see  some  sort  of  toxicity?  I’m  not   talking  drug  users  but  people  who  are  poisoned  to  buy  something  in  their   environment  that  affects  their  brain.  Is  it  common  or  uncommon  in  your   practice?     Dr.  Amen:   It’s  very  common  especially  for  people  who  are  not  getting  better.  It’s  why  I   got  hooked  on  imaging  because  I  mean  you  could  come  and  you  could  say,   “I’m  having  trouble  with  my  focus  and  my  mood  is  not  good.”  Most   psychiatrist  would  do  a  checklist  with  you  and  go,  “You  have  depression,   you  have  ADD,  it’s  your  character  and  give  you  psychotherapy  or   medication,”  all  of  which  could  hurt  you  if  they  don’t  really  understand  the   cause.       Without  looking,  we  don’t  know.  By  looking  it  causes  us  to  try  and  find  out   why.  I  mean,  you  had  to  ask  yourself  why  does  this  psychiatrist  know   anything  about  mold.  They  didn’t  teach  me  one  thing  in  medical  school  or   during  my  psychiatric  residency  but  as  soon  as  I  started  seeing  toxic  brains   in  people  who  I  believe  were  not  using  drugs,  I’m  like  well,  why  is  that?       Actually,  it  was  a  woman  in  Northern  California  who  came  in  and  just  the   nicest  woman.  She  had  a  toxic  brain.  That’s  when  we  discovered  she  had   mold  in  her  house.  When  she  moved  down  and  we  rehabilitated  her  brain,   she  just  felt  so  much  better.     Dave:   You’ve  been  doing  this  now  since  1989.  That’s  roughly  pushing  on  almost   20  years  now  of  doing  brain  imaging  and  running  across  this.  How  does  the   brain  imaging  that  you  use,  work?  Someone  who  hasn’t  read  any  of  your  9   New  York  Times  bestsellers  and  your  latest  book  about  ADD,  can  you  walk   us  through  how  SPECTs  works  and  then  how  you’d  apply  that  to  say,  “Hey,   here’s  how  you  can  work  better.”     5 Bulletproof Toolbox Podcast #227, Dr. Daniel Amen Dr.  Amen:   I  went  to  a  lecture  on  brain  SPECT  imaging  in  1991.  It  just  radically  changed   everything  I  did.  SPECT  is  a  nuclear  medicine  study.  It  looks  at  blood  flow   and  activity.  It  looks  at  how  your  brain  works.  It’s  different  than  a  CT  scan   or  an  MRI,  those  are  anatomy  studies,  they  show  what  the  brain  actually,   physically  looks  like.  SPECT  looks  at  function.       If  you  just  think  about  a  car  engine.  If  you  pop  the  hood,  an  MRI  or  a  CT  will   show  you,  well,  this  is  what  the  engine  actually  looks  like.  SPECT  is  like   turning  it  on  and  seeing  how  it  actually  works.  It  basically  tells  us  3  things   about  the  brain,  healthy  activity.  Good  activity  too  little  or  too  much.  Then   my  job  becomes  understanding  why  it  is  the  way  it  is  and  then  balancing  it.       If  it’s  too  low,  in  your  case,  then  we  got  to  go,  well,  why  is  it  too  low   trauma,  toxins  and  infections.  Now,  let’s  rehabilitate  it  and  if  you  think   about  how  do  you  …  I  like  orchids.  I  have  them  in  my  office.  If  the  orchid   was  damaged  either  by  toxins  in  the  soil  or  storm,  what  do  you  do?  Well,   the  first  thing  you  do  is  you  stop  the  toxins.  You  get  rid  of  the  toxins  and   then  you  give  it  the  highest  quality  nutrients,  air,  water,  possible  so  that  it   can  heal.       You  have  to  put  the  brain  in  a  healing  environment,  but  without  looking,   quite  frankly,  you  don’t  know.  You  don’t  know  is  it  a  toxin,  is  it  a  head   injury,  does  their  brain  work  too  hard  or  not  hard  enough.  We’ve  now  done   110,000  scans  on  people  from  111  countries.  I  love  it  because  I  like  getting   my  patients  better  fast,  a  big  criticism  of  me  when  I  was  a  child  psychiatry   fellow.       My  supervisor  loved  me  but  he  said,  “Dr.  Amen’s  biggest  problem  is  he   wants  people  to  get  better  fast.”  I’m  just  not  that  patient  because  I  know  if   I  was  suffering  I  wouldn’t  want  to  be  3  years  on  a  psychiatrist  couch.  I   would  like  go  so  let’s  find  it  and  fix  it.  I  have  this  bias  fraction  but  if  I  don’t   look  then  I’m  flying  blind.       I  like  to  say  a  picture  is  worth  a  thousand  words  but  a  map  is  worth  a   thousand  pictures.  That’s  what  we  do  with  SPECT.  We  map  your  brain  and  a   map  tells  you  where  you  are.  When  you  first  came  to  us,  it’s  like  your  brain   is  not  in  a  good  place.  It  gives  you  the  pathway  to  teach  you  where  you   6 Bulletproof Toolbox Podcast #227, Dr. Daniel Amen want  to  go.  What  I’m  so  excited  about  your  map  is  it  was  really  trouble   when  we  started  but  now  it’s  much  better.  I’m  just  so  excited  about  that.     Dave:   I  was  too.  I  didn’t  plan  on  talking  to  you  specifically  about  my  brain  map   there  and  in  fact  I’ll  take  a  screenshot  of  it.  I  think  I  have  to  get  the  digital   version  from  you  or  some  of  that  but  I’ll  actually  post  my  before  and  after   on  the  blog  so  people  can  see  what  a  radical  transformation,  getting  rid  of   toxins  from  your  environment  and  from  your  food.       Eating  enough  fat  for  your  brain  and  all  those  things  where  you  and  I  are  I   think  pretty  aligned.  I’m  sure  there’s  some  differences  in  small  nuance   things.  Directionally,  we’re  both  like  could  you  get  the  good  stuff  in?  Are   you  in  a  position  to  talk  about  that  news?  You  gave  me  a  case  of  something   special  at  your  office.  Can  we  talk  about  those  yet,  those  coconut  things?     Dr.  Amen:   Of  course.     Dave:   Let’s  use  those  as  examples  because  you  have  these  amazing  chocolate   coconut  things  that  are  …  I  actually  ate  almost  the  whole  case.  My  kids  got   only  1.  This  is  just  a  great  example  of  how  you  formulate  this  amazing  …  I   don't  know  if  you  call  it  a  treat  or  a  bar.  It’s  almost  all  fat.  Why  do  you  make   something  like  that  that’s  almost  all  fat?  What’s  it  called?  It’s  a  really  cool   name  but  I’m  thinking  like  Brain  on  …     Dr.  Amen:   Joy.     Dave:   Brain  on  Joy.     Dr.  Amen:   We  have  just  the  chocolate  one  called  Brain  and  Love.  Why  is  this   psychiatrist  making  chocolate  bars?  It’s  a  symbol  of  abundance  that  getting   well  is  never  about  deprivation.  You  got  to  shift  your  mind.  It’s  abundance   of  the  right  things  that  serve  your  health  that  can  also  taste  amazing.  The   whole  low  fat  craze,  that  was  a  mistake.       60%  of  the  solid  weight  of  your  brain  is  fat.  Low  cholesterol  levels  have   actually  been  associated  with  homicide,  suicide  and  depression.  That   cholesterol  is  not  the  problem,  that  it’s  sugar.  It’s  high  inflammatory  diets   7 Bulletproof Toolbox Podcast #227, Dr. Daniel Amen and  knowing  what  I  know  about  your  work,  I  mean  we’re  very  aligned  and   basically  like  with  the  orchid,  you  want  to  stop  poisoning  it  and  only  give  it   nutrients  that  serve  its  health.       I  really  think  of  high  healthy  fat.  Not  all  fat  is  good,  high  healthy  fat,  low-­‐ glycemic,  high  fiber  carbs.  Carbs  are  not  the  enemy,  it’s  bad  carbs  that  are   the  enemy.  Colorful  foods,  not  Skittles  but  foods  with  many  different  colors   because  they  have  huge  antioxidant  support  and  protein  at  each  field   because  protein  helps  stabilize  blood  sugar  levels.  When  your  blood  sugar   goes  low,  blood  flow  to  the  brain  goes  low  and  then  you  have  more,  make   more  bad  decisions.     Dave:   Did  you  just  say  that  having  blood  sugar  in  the  brain  is  good  for  you?     Dr.  Amen:   Having  high  blood  sugar  levels  is  associated  with  brain  atrophy.  We  want  to   stabilize  your  blood  sugar.  When  blood  sugar  levels  go  to  low,  blood  flow  to   the  brain  goes  low  and  then  people  make  bad  decisions.  If  you  have   problems  with  addiction,  and  you  don’t  want  to  relapse  you  have  to  eat   healthy  food  often  enough  so  that  you  don’t  get  hungry.  That  is  associated   with  relapse.     Dave:   There’s  this  whole  trend  where  we  demonize  something.  Sugar  is  bad  and   generally  eating  sugar  is  not  a  good  choice  but  that  doesn’t  mean  that   having  some  blood  sugar  in  your  body  is  a  bad  thing.  You  die  without  it  and   just  like  you  said,  you  make  worse  decisions  when  you  don’t  have  enough   brain  fuel.       This  has  been  a  large  part  of  the  more  recent  toxin  that’s  been  around.   Where  does  willpower  come  from?  If  you  have  no  energy  in  the  brain,   whether  from  sugar  or  from  fat,  you  don’t  like  what  happens.  If  you  had  a   kale  salad  with  fat  free  dressing,  for  lunch,  you  simply  don’t  have  enough   sugar  or  calories  to  fuel  your  brain  and  it’s  no  wonder  you’re  going  to  be  a   little  bit  cranky.       Do  you  actually  see  them  on  brain  scans  or  someone  is  really  hungry?  Does   their  brain  look  different  if  they’ve  been  fasting  for  a  few  days  or  they’re   just  calorically  deprived  or  too  low  in  blood  sugar?     8 Bulletproof Toolbox Podcast #227, Dr. Daniel Amen Dr.  Amen:   There’s  actually  an  interest  in  people  who  are  around  the  net  and  actually   in  some  very  popular  books  talking  about  how  important  fasting  is.  I’m  not   a  fan.  I’m  a  fan  of  routine,  of  doing  really  great  things  for  your  brain   because  when  you  fast  and  your  blood  sugar  goes  low,  people  are  just   more  likely  to  make  bad  decisions.       Sugar  on  the  other  hand,  are  high  sugar  diets  because  you  know  when  they   took  the  fat  out  of  the  food,  they  replaced  it  with  sugar.  Diabetes  has   skyrocketed.  One  of  the  big  things  we’ve  learned  is  that  even  high  normal   blood  sugar  levels.  Blood  sugar  is  normal  between  65  and  100.  They  found   that  people  are  up  closer  to  100,  had  brain  atrophy.       It  accelerates  brain  aging.  I  like  your  blood  sugar  around  85.  I  think  that’s   healthy  for  you.  One  of  the  things  we  should  talk  about  is  if  you  really  want   to  keep  your  brain  and  healthy  as  you  age.  You  should  never  have  normal   labs.  You  should  have  optimal  labs.  See,  neither  you  or  I  or  most  of  the   people  watching  have  ever  wanted  to  be  normal  or  in  the  middle  of  our   classes  or  the  bottom  of  our  classes.       I’m  always  thinking  about  what’s  the  optimal  range  of  vitamin  D,  blood   sugar,  cholesterol,  C-­‐reactive  protein.  I  don’t  want  you  normal  because   quite  frankly  normal  is  sick.  If  you  live  to  85  or  beyond,  50%  of  people  will   have  Alzheimer's  disease.  That’s  normal  and  I  want  no  part  of  that.     Dave:   We’re  going  to  call  that  out  in  quotes  on  the  screen  when  you  say  that   because  normal  is  not  good.  The  whole  point  of  Bulletproof  Radio,  we  have   more  than  200  episodes.  I  like  to  interview  people  who  are  experts  and  not   being  normal  and  people  who  are  all  about  super  human  performance.       Now,  I  want  to  ask  you.  I  came  in  because  I  basically  hit  the  wall.  My  brain   won’t  work  anymore.  I  can  feel  something  is  wrong  but  have  you  ever  had   someone  like  an  Olympic  athlete,  a  top,  someone  who’s  a  CEO  of  a  Fortune   500  company  or  someone  come  in  who’s  doing  pretty  well.     I  like  my  life.  I’m  abundant,  I’m  high  performance,  I’m  helping  lots  of   people,  I’m  strong,  I’m  well.  Would  you  scan  a  brain  of  someone  who’s   already  a  super  high  performer?  What  do  you  often  find?  Is  there   9 Bulletproof Toolbox Podcast #227, Dr. Daniel Amen something  to  find  or  are  they  just  perfect  brains  and  that’s  why  they’re   performing  well?     Dr.  Amen:   Well,  I  have  a  whole  group  of  incredibly  beautiful  brains.  It  generally  goes   with  their  life  that  the  exercise  but  not  too  much  which  is  really  interesting   things.  My  extreme  athletes  usually  do  not  have  healthy  brains.  They  eat   well.  They’re  not  smoking,  they  don’t  really  think  about  alcohol  as  a  health   food.  Maybe  they  have  anywhere  from  2  to  4  glasses  a  week  but  not  2  to  4   glasses  a  day.  Their  habits  generally  reflect  the  health  of  their  brain.  Aging   is  more  about  actions  than  chronological  years  when  it  comes  to  the  brain.     Dave:   When  someone  with  one  of  these  beautiful  brains  comes  to  you.  They  have   beautiful  brain  and  beautiful  life,  are  there  tweaks  that  they  can  do  to  get   even  more  brain  performance  or  are  they  already  so  absurdly  high  that   really  it’s  like  there’s  not  much  to  be  done  here.     Dr.  Amen:   Well,  no.  There’s  always  tweaks.  We  can  always  do  better.  I  actually  have  a   program  called  The  Brain  Warrior’s  Way.  The  reason  for  the  title  is  because   I’ve  just  come  to  deeply  believe  we’re  in  a  war  for  the  help  of  our  brain.   Nearly  everywhere  we  go,  someone  is  trying  to  shove  bad  food  down  our   throat,  a  toxic  thought  in  our  head,  hook  us  to  a  gadget  that  will  distract  us   from  being  in  full  relationships.       If  you  have  the  mindset  of  a  warrior  which  means  …  It  doesn’t  mean  you’re   fighting.  Most  successful  warriors  never  fight.  It’s  because  they  plan,   they’re  aware,  they  know  who  is  friend  and  who  is  foe.  It  takes  that   mindset.  Most  of  us  can  be  into  that.  My  favorite  example  of  an  incredibly   beautiful  brain,  happens  to  be  my  mother’s.       In  1991,  I  started  scanning  people.  I  got  so  excited  about  the  technology.  I   scanned  everybody  I  knew,  a  friend  who  had  temper  problems.  I  scanned  a   cousin  who  had  suicidal  thoughts.  An  aunt  who  had  a  panic  disorder  and   then  after  I’ve  done,  I  don't  know,  maybe  100  scans  or  so,  they  scanned  my   mother  and  she  just  had  a  drop-­‐dead,  perfect  brain.       It  was  irritating  quite  frankly.  I  had  scan  myself  and  it  wasn’t  nearly  as  good.   I  looked  at  her  when  I  showed  her  perfect  brain  and  I  said  you  ruined  my   10

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