Table Of Content

Toxicology Letters Toxicology Letters 151 (2004) XVII-XIX www.elsevier.com/locate/toxlet Volume contents Volume 151 (2004) Special Issue: Festschrift dedicated to Christian Hodel Obituary Foreword Risk Assessment Safety evaluation of cosmetics in the EU. Reality and challenges for the toxicologist M. Pauwels and V. Rogiers (Belgium) Good Evaluation Practice: a proposal of guidelines T. Malmfors, P.D. Marco and K. Savolainen (Sweden, Australia, Finland) Safety pharmacology: an essential interface of pharmacology and toxicology in the non-clinical assessment of new pharmaceuticals J.-R. Claude and N. Claude (France) Carcinogenicity categorization of chemicals—new aspects to be considered in a European perspective H.M. Bolt, H. Foth, J.G. Hengstler and G.H. Degen (Germany) Risk assessment of peak exposure to genotoxic carcinogens: a pragmatic approach P.M.J. Bos, B.-J. Baars and M.T.M. van Raaij (The Netherlands) Environmental Toxicology Dioxins, dioxin-like PCBs and non-dioxin-like PCBs in foodstuffs: occurrence and dietary intake in The Netherlands A.J. Baars, M.I. Bakker, R.A. Baumann, P.E. Boon, J.I. Freijer, L.A.P. Hoogenboom, R. Hoogerbrugge, J.D. van Klaveren, A.K.D. Liem, W.A. Traag and J. de Vries (The Netherlands) Heavy metals (Ni, Cr, Cu) in the Karoon waterway river, Iran V. Diagomanolin, M. Farhang, M. Ghazi-Khansari and N. Jafarzadeh (Iran) Molecular Toxicology Response of rat alveolar type II cells and human lung tumor cells towards oxidative stress induced by hydrogen peroxide and paraquat E. Weidauer, T. Lehmann, A. Ramisch, E. ROhrdanz and H. Foth (Germany) The effect of curcumin on cadmium-induced oxidative damage and trace elements level in the liver of rats and mice V. Eybl, D. Kotyzova and M. Bludovska (Czech Republic) Modulation of glucose uptake in glial and neuronal cell lines by selected neurological drugs M. Mannerstr6m and H. Tahti (Finland) Interaction of mercury(I) with the microtubule cytoskeleton in IMR-32 neuroblastoma cells T. Stoiber, G.H. Degen, H.M. Bolt and E. Unger (Germany) The thiol reactivity of the oxidation product of 3,5,7-trihydroxy-4H-chromen-4-one containing flavonoids G. Michels, G.R.M.M. Haenen, W. Watjen, S. Rietjens and A. Bast (Germany, The Netherlands) Genotoxicity and Carcinogenesis Genotoxicity of hormonal steroids H.F.P. Joosten, F.A.A. van Acker, D.J. van den Dobbelsteen, G.J.M.J. Horbach and E.I. Krajnc (The Netherlands) Comparative metabolic activation of benzidine and N-acetylbenzidine by prostaglandin H synthase G.H. Degen, J.H. Schlattjan, S. Mahler, W. Follmann and K. Golka (Germany) doi: 10.1016/S0378-4274(04)00329-7 XVIII Volume contents The modulating effects of quercetin and rutin on the mitomycin C induced DNA damage eee, o. Apoin, A. Almnet Bageren and N. Bagaran (Tutkey) . ccaee heen ncawes 143 Genotoxicity of the isoflavones genistein, daidzein and equol in V79 cells Ais. Vago, &.. wenn, W. Wagen, KR. Kahl and G.H: Degen (Germany) ow ew ccc tee c new ncnes Neurotoxicology Bovine chromaffin cell cultures as model to study organophosporus neurotoxicity rr rn rn ar wer Ge W, SUE CEE) ni ke ok eh Ree ee eee eee we ee ee ete e ee eees 163 The inhibition of the high sensitive peripheral nerve soluble esterases by mipafox. A new mathematical processing for the kinetics of inhibition of esterases by organophosphorus compounds J. Estévez, A.G. Garcia-Pérez, J. Barril, M. Pellin and E. Vilanova (Spain) .....0. c.c cc.c cc. e.e .eee .ee e 171 Neurobehavioral effects of experimental exposures to low levels of styrene A. Seeber, M. Blaszkewicz, K. Golka, E. Hallier, E. Kiesswetter, M. Schaper and C. van Thriel (Germany) ............ 183 Colour vision and occupational toluene exposure: results of repeated examinations Di. wcmeet, F. temmes, EB. Risesswetier, Mi. Cipanic and A. Seever (Germany) . nn eeee e ee eee Industrial Toxicology Carcinogenicity of azo colorants: influence of solubility and bioavailability ee ee a Oe Syne Gah a Nee A edie SK ae oe ae wR Re eee eee hw Oe 6 O58 203 Assessing the genotoxicity of industrial cutting fluids under conditions of use rn or er a oe, NCE HERONS a A Ch EN AM hele Obl ed eee eee eee eee Clinical Toxicology Future applications of phosphotriesterases in the prophylaxis and treatment of organophosporus insecticide and nerve agent poisonings eB reg rae rere are erie eee Wear er ere ara a a er re 219 Carbohydrate-deficient transferrin (CDT) as a biomarker in persons suspected of alcohol abuse a. Se a, ES, Shun, SUCEUD AUN A, WeEOO TOPCTIMEY) gk a ie ee wee eb eee eee ewe bb eee fh Detection of clinical interactions between methadone and anti-retroviral compounds using an enantioselective capillary electrophoresis for methadone analysis J. Esteban, M. de la Cruz Pellin, C. Gimeno, J. Barril, E. Mora, J. Giménez and E. Vilanova (Spain) ................ 243 1,3-Propane sultone, an extremely potent experimental carcinogen: what should be expected in humans? ae cg a hh a VER Aes SASS EWE Ow EO ED hee ee RO 251 Molecular Epidemiology Challenges to environmental toxicology and epidemiology: where do we stand and which way do we go? B. Pesch, T. Briining, R. Frentzel-Beyme, G. Johnen, V. Harth, W. Hoffmann, Y. Ko, U. Ranft, U.G. Traugott, R. Thier, D. Taeger and ee gs lie a EN a Nie VTE Ete a th ATR OS ORO BIS MER AA MEA OME Owe we RS 255 A tetranucleotide repeat polymorphism in the CYP/9 gene and breast cancer susceptibility in a Greek population exposed and not exposed to pesticides i ee, oa, en, Ga. Bee GORE AA. DPO ORRMCIE CE MPOGOE) © ow 6k 5 ia eee ede ee eee eb eweees 267 Association of cytochrome P450 2E1 polymorphisms and head and neck squamous cell cancer T. Neuhaus, Y.-D. Ko, K. Lorenzen, S. Fronhoffs, V. Harth, P. Brode, H. Vetter, H.M. Bolt, B. Pesch and T. Briining (Germany) 273 Polymorphic metabolic susceptibility genes and longevity: a study in octogonarians B. Pesch, R. Diising, S. Rabstein, V. Harth, D. Grentrup, T. Briining, O. Landt, H. Vetter and Y.-D. Ko (Germany) ....... 283 A pilot study on the application of statistical classification procedures to molecular epidemiological data H. Schwender, M. Zucknick, K. Ickstadt, H.M. Bolt and The GENICA network (Germany, UK) .................... 291 VAL mutations in renal cell cancer: does occupational exposure to trichloroethylene make a difference? H. Brauch, G. Weirich, B. Klein, S. Rabstein, H.M. Bolt and T. Briining (Germany) ..................2 e2e0 ee2e e 301 Polymorphisms of cytochrome P450 1A1, glutathione S-transferases M1 and T1 in a Turkish population oy a 8 aly Gigi ad ate R SAS Pe ed Oa ke we een os Gwe Ra BAe RN KS 311 EE EE NLS EE BEE EON at Se IES ayo h UT APY aE re oy PR eee aa PE a ae ee are I The evaluation of the acute toxicity and long term safety of hydroalcoholic extract of Sapthaparna (A/lstonia scholaris) in mice and rats M.S. Baliga, G.C. Jagetia, J.N. Ulloor, M.P. Baliga, P. Venkatesh, R. Reddy, K.V.N. Mallikarjun Rao, B.S. Baliga, S. Devi, oa mee, ¥. VOOreee, 2. peeey ame mM. Laxwineravens Bary (INdis) jw ee aes ee eee e wena Volume contents A method for studies on milk excretion of chemicals in mice with 2,2’,4,4’,5-pentabromodipheny] ether (BDE-99) as a model A. Oskarsson and N. Moller (Sweden) The protective effect of taurine against cyclosporine A-induced oxidative stress and hepatotoxicity in rats H.H. Hagar (Saudi Arabia) Benzo[a]pyrene diol epoxide up-regulates COX-2 expression through NF-«B in rat astrocytes M.-W. Weng, Y.-M. Hsiao, C.-J. Chen, J.-P. Wang, W.-C. Chen and J.-L. Ko (Taiwan) Induction of oxidative stress by endosulfan and protective effect of lipid-soluble antioxidants against endosulfan-induced oxidative damage H.-Y. Sohn, C.-S. Kwon, G.-S. Kwon, J.-B. Lee and E. Kim (South Korea) Activation and up-regulation of nitric oxide synthase in human umbilical vein endothelial cells by polycyclic aromatic hydrocarbons C.-H. Li, C.-C. Lee, Y.-W. Cheng, H.-A. Juang and J.-J. Kang (Taiwan) Involvement of cytochrome P450 1A in sanguinarine detoxication J. Vrba, P. Kosina, J. Ulrichova and M. Modriansky (Czech Republic) Adjuvant effect of quaternary ammonium compounds in a murine model S.T. Larsen, R. Hansen, M. Hammer, U. Tegner, O.M. Poulsen and G.D. Nielsen (Denmark) Instructions to authors Review The traditional categories of fluoroacetate poisoning signs and symptoms belie substantial underlying similarities M. Sherley (Australia) New data on biological effects of chlorhexidine: Fe** induced lipid peroxidation and mitochondrial permeability transition A.P. Negrelo Newton, S.M.S.C. Cadena, M.E. Merlin Rocha, E.G. Skare Carnieri and M.B. Martinelli de Oliveira (Brazil) Comparative effects of technical toxaphene, 2,5-dichloro-3-biphenylol and octabromodiphenylether on cell viability, [Ca**]; levels and membrane fluidity in mouse thymocytes S. Sandal, B. Yilmaz, C.-H. Chen and D.O. Carpenter (Turkey, USA) The effects of tobacco smoke on plasma alpha- and gamma-tocopherol levels in passive and active cigarette smokers A. Sobczak, D. Gotka and I. Szottysek-Botdys (Poland) Potent inhibition of gap junctional intercellular communication by 3-chloro-4-(dichloromethyl)-5-hydroxy-2(5H)-furanone (MX) in BALB/c 3T3 cells P. Hakulinen, J. Maki-Paakkanen, J. Naarala, L. Kronberg and H. Komulainen (Finland) Reduction of erythrocyte catalase and superoxide dismutase activities in male inhabitants of a cadmium-polluted area in Jinzu river basin, Japan M. Uchida, H. Teranishi, K. Aoshima, T. Katoh, M. Kasuya and H. Inadera (Japan) Acute exposure to cobalt induces transient methemoglobinuria in rats H. Horiguchi, E. Oguma, S. Nomoto, Y. Arao, K. Ikeda and F. Kayama (Japan) Effect of in vitro estrogenic pesticides on human oestrogen receptor « and fh mRNA levels H.T. Griinfeld and E.C. Bonefeld-Jorgensen (Denmark) Genotoxic potentiality of aqueous extract prepared from Chrysobalanus icaco L. leaves S.C. Ferreira-Machado, M.P. Rodrigues, A.P.M. Nunes, F.J.S. Dantas, J.C.P. De Mattos, C.R. Silva, E.G. Moura, R.J.A.C. Bezerra and A. Caldeira-de-Araujo (Brazil) Response to: artemisinin derivatives: toxic for laboratory animals, safe for humans? S. Toovey and A. Jamieson (South Africa) Response to the Letter to the Editor by Stephen Toovey and Andrew Jamieson T. Gordi and E.-I. Lepist (USA) Report by the Editors Author index Subject index Volume contents