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Toxicology Letters 1993: Vol 68 Index PDF

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Toxicology Letters, 68 (1993) 333-334 Elsevier Science Publishers B.V. AUTHOR INDEX VOL. 68 (1993) Ali, B., see Siddiqui, A., 301 based pharmacokinetic (PBPK) model parame- Andersen, M.E., see Mills, J.J., 177 ters and their effects on PBPK model predic- Arias, R.N. and de Peretti, A.F., Effects of 2,4- tions in a risk assessment for perchloroethylene dichlorophenoxyacetic acid on Rhizobium sp. (PCE), 131 growth and characterization of its transport, Gibson, G.G., Peroxisome proliferators: Para- 267 digms and prospects, 193 Grabau, J.H., Animal issues and society, 51 Brashear, W.T., see Dodd, D.E., 37 Green, S., Regulatory agency considerations and Bull, R.J., Templin, M., Larson, J.L. and Stevens, requirements for validation of toxicity test al- D.K., The role of dichloroacetate in the hepa- ternatives, 119 tocarcinogenicity of trichloroethylene, 203 Greene, R.J., see Gearhart, J.M., 131 Caldwell, D.J., Use of alternative endpoints with Hancock, B.L., see Channel, S.R., 213 the UPitt I] method for assessing the toxicity of Hansen, L.G., see Ness, D.K., 311 smoke, 241 Harkema, J.R. and Hotchkiss, J.A., Ozone- and Clewell III, H.J., see Gearhart, J.M., 131 endotoxin-induced mucous cell metaplasias in Clewell III, H.J., Coupling of computer modeling rat airway epithelium: Novel animal models to with in vitro methodologies to reduce animal study toxicant-induced epithelial transforma- usage in toxicity testing, 101 tion in airways, 25] Channel, S.R. and Hancock, B.L., Application of Hiller, R.G., see Wilkinson, J.M., 285 kinetic models to estimate transit time through Hotchkiss, J.A., see Harkema, J.R., 251 cell cycle compartments, 213 Huang, Y.-S. and Sultatos, L.G., Glutathione-de- pendent biotransformation of methyl parathi- DelRaso, N.J., In vitro methodologies for en- on by mouse liver in vitro, 275 hanced toxicity testing, 91 Dodd, D.E., Brashear, W.T. and Vinegar, A.., Kienholz, E., see Siblerud, R.L., 307 Metabolism and pharmacokinetics of selected Kolmer, J.W., Current DoD policy on use of ani- Halon replacement candidates, 37 - mals in research, 59 Dodd, D.E., see McDougal, J.N., 31 Komulainen, H., see Risto, L., 325 Kucharz, E.J. and Olezyk, K., Influence of chron- Fisher, J.W., Estimating the risks of liver and lung ic intoxication with selenium on collagen and cancer in humans exposed to trichloroethylene elastin content in tissues of rat, 295 using a physiological model, 127 Fisher, J.W., see Gearhart, J.M., 131 Larson, J.L., see Bull, R.J., 203 Flemming, C.D., see Gearhart, J.M., 131 Li, K., see Wilkinson, J.M., 285 Frazier, J.M., In vitro models for toxicological research and testing, 73 Mahle, D.A., see Gearhart, J.M., 131 Frederick, C.B., Limiting the uncertainty in risk McDougal, J.N. and Dodd, D.E., Air Force ap- assessment by the development of physiologi- proach to risk assessment for Halon replace- cally based pharmacokinetic and pharmacody- ments, 31 namic models, 159 McMaster, S.B., Developmental toxicity, repro- ductive toxicity, and neurotoxicity as regulato- Gearhart, J.M., Mahle, D.A., Greene, R.J., Seck- ry endpoints, 225 el, C.S., Flemming, C.D., Fisher, J.W. and Cle- Mills, J.J. and Andersen, M.E., Dioxin hepatic well III, H.J., Variability of physiologically 334 carcinogenesis: Biologically motivated model- Schantz, S.L., see Ness, D.K., 311 ing and risk assessment, 177 Seckel, C.S., see Gearhart, J.M., 131 Morehouse, E.T., Overview — Air Force policy on Siblerud, R.L., Kienholz, E. and Motl, J., Evi- halons, 11 dence that mercury from silver dental fillings Moshtaghian, J., see Ness, D.K., 311 may be an etiological factor in smoking, 307 Motl, J., see Siblerud, R.L., 307 Siddiqui, A., Ali, B. and Srivastava, S.P., Effect of mancozeb on hepatic glutathione S-transferase Ness, D.K., Schantz, S.L., Moshtaghian, J. and in rat, 301 Hansen, L.G., Effects of perinatal exposure to Srivastava, S.P., see Siddiqui, A., 301 specific PCB congeners on thyroid hormone Stevens, D.K., see Bull, R.J., 203 concentrations and thyroid histology in the rat, Sultatos, L.G., see Huang, Y.-S., 275 311 Templin, M., see Bull, R.J., 203 O'Flaherty, E.J., A pharmacokinetic model for Tilson, H.A., Neurobehavioral methods used in chromium, 145 neurotoxicological research, 231 Olezyk, K., see Kucharz, E.J., 295 Trochimowicz, H.J., Industrial research on alter- native fluorocarbons, 25 de Peretti, A.F., see Arias, R.N., 267 Pollard, I., see Wilkinson, J.M., 285 Vartiainen, T., see Risto, L., 325 Vinegar, A., see Dodd, D.E., 37 Risto, L., Vartiainen, T. and Komulainen, H., Formation of methemoglobin by 3-chloro-4- Walsh, D.A., see Wilkinson, J.M., 285 (dichloromethyl)-5-hydroxy-2(5H)-furanone, Wilkinson, J.M., Pollard, I., Walsh, D.A., Hiller, MX, in rat erythrocytes in vitro, 325 R.G. and Li, K., Caffeine does not increase Rowan, A.N., Formulation of ethical standards synthesis of heat shock proteins in rat embryos, for use of animals in medical research, 63 285 Rubenstein, R., Human health and environment- al toxicity issues for evaluation of halon re- placements, 21 Toxicology Letters, 68 (1993) 335-336 Elsevier Science Publishers B.V. SUBJECT INDEX VOL. 68 (1993) Air Force halon uses, 11 Fluorocarbon alternatives, 25 Air Force Regulation 19-15, 11 Airway epithelium, 251 Glutathione, 275 Alternative end points, 241 Glutathione S-transferase, 301 Alternatives, 119 Growth factor, 177 Animal activists, 51 Animal issues, 51 Halon 1211, 37 Animal patents, 51 Halon replacement, 31 Animal research, 51, 63 Halon replacements, 11 Animal rights, 63, 51 Halon substitute, 21 Animal use, 51 HCFC-123, 37, 25 Animal welfare, 51 HCFC-124, 37, 25 Animals in research, 59 HCFC-142b, 37 Arsenate, 267 Hemoglobin, 325 Hepatocarcinogenicity, 193, 203 Behavioral toxicology, 231 Hepatocyte, 91 Biologically based risk assessment, 159 HFC-125, 25 HFC-134a, 25 Caffeine, 285 hsp 25, 285 Cancer risk assessment, 159 hsp 70, 285 Carcinogenesis, 213 hsp 90, 285 Cardiotoxicity, 21 Hydrochlorofluorocarbon, 37 Cell cycle, 213 Hydrochlorofluorocarbons, 25 Chemical risk assessment, 101 Hydrofluorocarbons, 25 Chloramphenicol, 267 Hydroxyproline, 295 3-Chloro-4-(dichloromethyl)-5-hydroxy-2(5H)- furanone, 325 In vitro, 91, 119, 73 Chromium, 145 In vitro methods, 101 Collagen, 295 Combustion toxicology, 241 Kinetic model, 213 Cytochrome P-450, 177 Cytochrome P4504 family, 193 Mancozeb, 301 2,4-D, 267 Mercury, 307 Methemoglobin, 325 Dental amalgam, 307 Methods, 91, 231 Department of Defense, 59 Methyl parathion, 275 Developmental toxicity, 225 Model, 177 Dichloroacetate, 203 Mucous cell metaplasia, 251 Elastin, 295 Neurotoxicity, 225 Endotoxin, 251 Neurotransmitter, 307 Ethics, 63 Nonmutagenic carcinogen, 193 Ethyl acrylate, 159 Organophosphate biotransformation, 275 Fire extinguishing, 21 Oxidative damage, 325 336 Ozone, 251 Smoke toxicity, 241 Smoking, 307 PBPK, 177 Sodium azide, 267 PBPK modeling, 101 Sodium selenite, 295 PCB, 311 Perchloroethylene, 131 TCDD, 177 Perfluorohexane, 37 Test guidelines, 225 Perinatal, 311 Tetrachloroethylene, 131 Peroxisome proliferator, 193 Thyroid, 311 Pharmacokinetic models, 31 Thyroxine, 311 Pharmacokinetics, 101 Tier-testing, 231 Physiological modeling, 101 Toxicity, 119 Physiologically based model, 145 Toxicity testing, 73 Physiologically based pharmacokinetic modeling, Trichloroacetate, 203 127 Trichloroethylene, 127, 203 Physiologically based pharmacokinetic (PBPK) Trifluoroacetic acid, 37 model, 131, 159 Triiodothyronine, 311 Tumor promotion, 177 Rat, 311, 145 Rat embryo, 285 Uncertainty in cancer risk assessment, 159 Rat liver, 301 UPitt II method, 241 Regulation, 59 Uptake, 267 Rhizobium, 267 Risk assessment, 127, 225, 31, 131 Validation, 119, 73 Screens, 91 Water chlorination, 325

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