Table Of Content

Vol. 59 Nos. 1-3 DECEMBER 1991 TOXICOLOGY LETTERS An International Journal for the Rapid Publication of Short Reports on Biochemical Mechanisms of Mammalian Toxicity CONTENTS Commentary Commentary on ‘Assessment of safety/risk of chemicals: inception and evolution of the ADI and dose-response modeling procedures’ by Frank C. Lu and Robert L. Sielken Jr J.F. Borzelleca (U.S.A.) Minireview Assessment of safety/risk of chemicals: inception and evolution of the ADI and dose-response modeling procedures F.C. Lu and R.L. Sielken Jr. (U.S.A.) Research Letters Evidence of hepatic conversion ofC , and C, chlorotrifluoroethylene (CTFE) oligomers to their corresponding CTFE acids N.J. DelRaso, K.L. Auten, H.C. Higman and H.F. Leahy (U.S.A.) Benzo[e]pyrene pretreatment of immature, female C57BL/6J mice results in increased bioactivation of aflatoxin B, in vitro X. Ma, J.A. Gibbons and J.G. Babish (U.S.A.) Neurotoxic effects of 2,5-hexanedione on growing peripheral nerve axons of rat fetuses Y. Ogawa, T. Komatsu, N. Fujikake, T. Fujii and J. Tanaka (Japan) Depletion of brain serotonin does not alter 2,3,7,8- tetrachlorodibenzo-p-dioxin (TCDD)-induced starvation syndrome in the rat B.U. Stahl, R.H. Alper and K. Rozman (U.S.A., F.R.G.) Regulation of metallothionein production in HeLa cells S. Koizumi and T. Sone (Japan) Cocaine immunotoxicity: abnormal cytokine production in Hispanic drug users G.-J. Chen, R. Pillai, J.R. Erickson, F. Martinez, A.L. Estrada and R.R. Watson (U.S.A.) Defluorination of the CFC-substitute | ,1,1,2-tetrafluoroethane: comparison in human, rat and rabbit hepatic microsomes M.J. Olson and S.E. Surbrook, Jr. (U.S.A.) Hexachlorobenzene and its metabolites pentachlorophenol and tetrachlorohydroquinone interaction with thyroxine binding sites of rat thyroid hormone carriers ex vivo and in vitro J.A.G.M. van Raaij, K.J.v.d. Berg and W.R.F. Notten (The Netherlands) Effects of sinefungin and 5S'-deoxy-5S'-S-isobutyl-adenosine on lipopolysaccharide-induced proliferation and protein N-methylation of arginyl residues in murine splenic lymphocytes B.R. Kim and K.H. Yang (Korea) Dehydration is the first step in the bioactivation of haloperidol to its pyridinium metabolite J. Fang and J.W. Gorrod (U.K.) Mobilization of cadmium by liposome-encapsulated meso-2,3-dimercaptosuccinic acid in pre- exposed mice S. Srivastava, S. Gupta, J.R. Behari and R.C. Srivastava (India) Durable inhibition of rat cerebral capillary Na*/K*-ATPase after in vivo administration of mercuric chloride J. Albrecht (Poland) Contents continuedo n page 262 Cited in: Agricola; Biological Abstracts; Chemical Abstracts; Current Contents ( Life Sciences); Environmental Mutagen Information Center; Excerpta Medica (EMBASE); Index Medicus; International Pharmaceutical Abstracts; Pascal M; Science Citations Index PRINTED IN THE NETHERLANDS 262 CONTENTS (continued from back cover ) Effects of probenecid and acivicin on potassium dichromate-induced acute nephrotoxicity in mice J. De Ceaurriz and M. Ban (France) Stimulation of natural killer cell activity by murine retroviral infection and cocaine T.S. Poet, R. Pillai, S. Wood and R.R. Watson (U.S.A.) The effects of thiamine and EDTA on biliary and urinary lead excretion in sheep A.A. Olkowski, $.R. Gooneratne and D.A. Christensen (Canada, New Zealand) Relationship between cholinesterase inhibition and thermoregulation following exposure to diisopropyl fluorophosphate in the rat C.J. Gordon, L. Fogelson, J. Richards and J. Highfill (U.S.A.) Elevated urinary excretion of B-aminoisobutyric acid and d-aminolevulinic acid (ALA) and the inhibition of ALA-synthase and ALA-dehydratase activities in both liver and kidney in mice exposed to lead K. Tomokuni, M. Ichiba and Y. Hirai (Japan) The effect of structurally divergent herbicides on mouse liver xenobiotic-metabolizing enzymes (P-450-dependent mono-oxygenases, epoxide hydrolases and glutathione S-transferases) and carnitine acetyltransferase D.E. Moody, B.A. Narloch, L.R. Shull and B.D. Hammock (U.S.A.) Binding of the strong bacterial mutagen, 3-chloro-4-(dichloromethyl)-5-hydroxy-2(5H)- furanone (MX) to bovine serum albumin L. Haataja, T. Vartiainen, S. Lampelo, S. L6tj6nen and J. Tuomisto (Finland) Transient heat shock in mid-G1-phase of the C6 glioma cell cycle impairs entry into S-phase M.L. Martin and C.M. Regan (Ireland) Uncoupling of oxidative phosphorylation in rat liver mitochondria by chloroethanols H.K. Bhat, G.K. Asimakiasn d G.A.S. Ansari (U.S.A.) Mutagenicity studies of kojic acid C.1. Wei, T.S. Huang, S.Y. Fernando and K.T. Chung (U.S.A.) Immunochemical and immunohistochemical studies of cadmium associated proteins in Rana tadpoles L.D. Zettergren, C.A. Conrad, D.H. Petering, D.N. Weber and M.S. Goodrich (U.S.A.) Ten-day repeated-exposure inhalation study of dimethylformami(dDMeF ) in cynomolgus monkeys M.E. Hurtt, K.T. McCooey, M.E. Plancke and G.L. Kennedy (U.S.A.) Wy-14,643 but not 2-ethylhexanol increases intracellular free calcium in cultured Kupffer cells I. Hijioka, B.J. Keller and R.G. Thurman (U.S.A.) Time course for the elevation of glutathione in numerous organs of L1210-bearing CDF 1 mice given the L-cysteine prodrug, RibCys J.C. Roberts and D.J. Francetic (U.S.A.) Announcement Author Index ( Volume 59 Subject Index ( Volume 59 Notes to Authors