Table Of Content

TOXICOLOGY AS = ELSEVIER SCIENTIFIC PUBLISHERS IRFLAND Toxicology 86 (1994) 247-248 Volume Contents Volume 86 Publishers Announcement Genotoxicity of the phosphoramidate agent tabun (GA) (Positive results were obtained only in 3 out of 5 assays and GA is therefore considered to be weakly mutagenic) B.W. Wilson, T.G. Kawakami, N. Cone, J.D. Henderson, L.S. Rosenblatt, M. Goldman,J. C. Dacre (Davis, CA; Fort Detrick, MD) Cytotoxicity of dust constituents towards ini macvophnges: ij nteractions of heavy metal compounds (An unselectively permutated mixture of metal ions shows no predictable but describable interactions in the effect on yay anion formation) R. Geertz, H. Gulyas, G. Gercken (Hamburg, Germany) Protective effects of 2,3-v e Nit ee l-sulfonate on mercuric chistes induced acute inhibition of enzymes from rat duodenal mucosa and kidney cortex (DMPS may be useful in mitigating acute mercury poisoning) S. Suzuki, S. Takamura, K. Sugiki, M. Imai, O. Niwa, R. Tamatani (Ishikawa, Japan) Immunologic and endocrine effects of the flame-retardant pentabromodiphenyl ether (DE-71) in C57BL/6J mice (Subchronic exposure caused some modest immunotoxic response when measured as plaque-forming cell response to sheep erythrocytes, but did not affect natural killer cell activity) J.R. Fowles, A. Fairbrother, L. Baecher-Steppan, N.I. Kerkvliet (Corvallis, OR) 49-6] Reduced activity of tryptophan 2,3-dioxygenase in the liver of rats treated with chlorinated dibenzo- p-dioxins (CDDs): dose-responses and structure-activity relationship (The metabolism of tryptophan may be related to the dioxin-induced inappetence) L.W.D. Weber, C.D. Palmer, K. Rozman (Neuherberg, Germany: Kansas City, KS) . Decreases in dopamine concentrations in adult, non-human primate brain persist following removal from polychlorinated biphenyls (It is concluded that the continued dysfunctions are due to the initial insult rather than to continuing presence of PCSs in the brain) R.F. Seegal, B. Bush, K.O. Brosch (Albany, NY) ; . Arylation of sulfhydryl groups in vitro by the naturally occurring sesquiterpenoid benzoquinone, avarone Arylation of sulfhydryl groups in vitro by the naturally occurring sesquiterpenoid benzoquinone, avarone) M.A. Belisario, R. Pecce, M. Maturo, S. De Rosa (Naples, Italy) Induction of cytochrome P4504A by the peroxisome proliferator perfluoro-n-octanoic uci (The compound increases not only . enzymes but also cytochrome P450 Al) M.J. Diaz, E. Chinje, P. Kentish, B. Jarnot, M. George, G. Gibson (Guildford, UK; Dayton, OH) 109-122 Distribution of chlordecone to liver plasma membranes and recovery from hepatobiliary dysfunction in rats (Chlordecone-induced hepatobiliary dysfunction manifests itself as reduced biliary phenolphthalein glucuronide excretion and reduced biliary mannitol clearance) L.G. Rochelle, L.R. Curtis (Corvallis, OR) ; Effect of 3-phenylamino-L-alanine on tryptophan binding to ratt hepatic nuclear convaleges dt is pewibhe that PAA or a breakdown compound becomes incorporated into proteins) H. Sidransky, E. Verney, J.W. Cosgrove, P.S. Latham (Washington, DC) Dithiothreitol reversal of allyl alcohol cytotoxicity in isolated rat hepatocytes (The very ‘site events ieading to cytotoxicity are reversible, even if glutathione is not restored to normal levels) L.E. Rikans, Y. Cai (Oklahoma City, OK) .... Elsevier Scientific Publishers Ireland Ltd. SSDI 0300-483X(94)02821-B 248 Volume Contents/Toxicology 86 (1994) 247-248 Publisher's Announcement Characterization of the developmental toxicity of di-n-buty! phthalate in rats (Treatment on days 13-15 at doses of 0.75 and 1.0 g/kg produced the highest number of fetuses with malformations) M. Ema, H. Amano, Y. Ogawa (Osaka, Japan) ca 163-174 Mechanism of mobilization of renal and hepatic cadmium by dithiocarbamates in mice (Data o dithiocarbamate-induced Cd mobilization inthe presence of probenecid, acivicin, gamma-glutamyl- peptidase and ureter ligation) S. Kojima, T. Kamenosono, H. Shimada, T. Funakoshi (Kumamoto, Japan) 175-186 Immunotoxicology Histopathology of the immune system as a tool to assess immunotoxicity (A review is presented on the use and value of histological findings in preclinical immunotoxicity assessment) H.-J. Schuurman, C.F. Kuper, J.G. Vos (Basel, Switzerland; Zeist and Bilthoven, The Netherlands) Fish as biomarkers in immunotoxicology (A review is presented on current issues of immunotoxicity studies in fish) P.W. Wester, A.D. Vethaak, W.B. van Muiswinkel (Bilthoven, Haren and Wageningen, Netherlands) Contents of Journals Relating to Toxicology 233-239 Subject Index 241-243 Author Index 245 247-248 rae eee sot