Table Of Content

Toxicology, 77 (1993) 265-268 Elsevier Scientific Publishers Ireland Ltd. TOXICOLOGY SUBJECT INDEX Volume 77 (1993) N-acetyl S-(1,2,3,4,4-pentachloro-l ,3-butadienyl) cadmium, nickel, toxicity, cytoskeleton, protein Leysteine, nephrotoxicity, halogenated al- sulfhydryls, glutathione, 65 kenes, hexachloro-1,3-butadiene, cysteine con- carbon tetrachloride, taurine, B-alanine, hepato- jugate B-lyase, glutamine transaminase K, toxicity, liver, increased susceptibility, 7 enzyme induction and inhibition, 133 carcinogenicity, risk assessment, porphyria, B-alanine, taurine, carbon _ tetrachloride, mixtures, relative potency, — threshold, hepatotoxicity, liver, increased susceptibility, chlorinated dibenzo-p-dioxins, 39 7 cardiotoxicity, doxorubicin, mitoxantrone, lipo- antioxidant, butylated hydroxyanisole (BHA), peroxidation, chemiluminescence, oxidative cytosolic calcium, endothelial cells, 115 stress, 31 apomorphine, organic solvent, N-propylnorapo- cell proliferation, N-nitrosodiethylamine (DEN), morphine, dopamine receptor, locomotion, Syrian golden hamster, lung tumors, ozone, spatial learning, 223 tumor modulation, 193 apoptosis, thymocytes, 2,3,7,8-tetrachlorodi- chemical form, inorganic mercury, N-benzyl-D- benzo-p-dioxin, arylhydrocarbon (Ah) recep- glucamine dithiocarbamate, D-penicillamine, tor, 103 2,3-dimercaptopropanol, biliary and urinary arachidonic acid, toxic oil syndrome, fatty acid excretion, intestinal reabsorption, 157 anilides, endothelial cells, eicosanoids, 51 chemiluminescence, doxorubicin, mitoxantrone, arsenic, disodium arsenate, gallbladder, chole- cardiotoxicity, lipoperoxidation, oxidative cystitis, rainbow trout, 233 stress, 31 arylhydrocarbon (Ah) receptor, thymocytes, chlorinated dibenzo-p-dioxins, risk assessment, apoptosis, 2,3,7,8-tetrachlorodibenzo-p-di- porphyria, mixtures, relative potency, carcino- oxin, 103 genicity, threshold, 39 atractyloside, nephrotoxin, proximal tubular chlorinated paraffins, hepatic peroxisome pro- toxin, hypoglycemia, hypoxemia, glucosuria, liferation, thyroid, 81 dogs, 259 cholecystitis, arsenic, disodium arsenate, gallbladder, rainbow trout, 233 behaviour, neurotoxicity, 1,1,1-trichloro-2,2-bis- chromium, cytotoxicity, unscheduled DNA syn- (p-chlorophenyl)-ethane (DDT), pyrethroid, thesis (UDS), DNA strand breaks, hepatocyte, interaction, muscarinic receptors, 21 171 N-benzyl-D-glucamine dithiocarbamate, chem- colloidal amorphous silica, epithelioid cell ical form, inorganic mercury, D-penicillamine, granulomas, colloidal amorphous silica, 2,3-dimercaptopropanol, biliary and urinary silicotic nodules, colloidal amorphous silica, excretion, intestinal reabsorption, 157 particle transmigration, colloidal amorphous biliary and urinary excretion, chemical form, in- silica, pulmonary lesions, 205 organic mercury, N-benzyl-D-glucamine di- colloidal amorphous silica, particle transmigra- thiocarbamate, D-penicillamine, 2,3-dimercap- tion, colloidal amorphous silica, silicotic topropanol, intestinal reabsorption, 157 nodules, colloidal amorphous silica, epithel- butylated hydroxyanisole (BHA), antioxidant, ioid cell granulomas, colloidal amorphous cytosolic calcium, endothelial cells, 115 silica, pulmonary lesions, 205 C57BL/6 mice, coplanar PCBs, teratogenicity, colloidal amorphous silica, pulmonary lesions, immunotoxicity, 123 colloidal amorphous silica, silicotic nodules, colloidal amorphous silica, particle trans- cadmium nephrotoxicity, glomerulus, mesangial migration, colloidal amorphous silica, epithe- cell, glutathione, metallothionein, 145 lioid cell granulomas, 205 266 colloidal amorphous silica, silicotic nodules, col- eicosanoids, toxic oil syndrome, fatty acid loidal amorphous silica, particle transmigra- anilides, endothelial cells, arachidonic acid, 51 tion, colloidal amorphous silica, epithelioid endothelial cells, butylated hydroxyanisole cell granulomas, colloidal amorphous silica, (BHA), antioxidant, cytosolic calcium, 115 pulmonary lesions, 205 endothelial cells, toxic oil syndrome, fatty acid contact sensitization, local lymph node re- anilides, eicosanoids, arachidonic acid, 51 sponses, dendritic cells, percutaneous absorp- enzyme activity, 2,3,7,8-tetrachlorodibenzo-p- tion, sodium lauryl sulphate, 2,4-dinitrochlo- dioxin, phosphoenolpyruvate carboxykinase, robenzene, 181 PEPCK mRNA, tryptophan 2,3-dioxygenase, coplanar PCBs, C57BL/6 mice, teratogenicity, P-450 1A1, 295 immunotoxicity, 123 enzyme induction and inhibition, nephrotoxicity, cysteine conjugate 8-lyase, nephrotoxicity, hal- halogenated alkenes, hexachloro-1,3-butadi- ogenated alkenes, hexachloro-1,3-butadiene, ene, N-acetyl-S-(1,2,3,4,4-pentachloro-1 ,3- N-acetyl-S-(1,2,3,4,4-pentachloro-1,3-butadi- butadienyl)-L-cysteine, cysteine conjugate B- enyl)-L-cysteine, glutamine transaminase K, lyase, glutamine transaminase K, 133 enzyme induction and inhibition, 133 cytoskeleton, cadmium, nickel, toxicity, protein fatty acid anilides, toxic oil syndrome, endothe- sulfhydryls, glutathione, 65 lial cells, eicosanoids, arachidonic acid, 51 cytosolic calcium, butylated hydroxyanisole fetal development, a-melanocyte stimulating hor- (BHA), antioxidant, endothelial cells, 115 mone (MSH), pigmentation, 91 cytotoxicity, chromium, unscheduled DNA synthesis (UDS), DNA strand breaks, hepato- gallbladder, arsenic, disodium arsenate, chole- cyte, 171 cystitis, rainbow trout, 233 glomerulus, cadmium nephrotoxicity, mesangial D-penicillamine, chemical form, inorganic mer- cell, glutathione, metallothionein, 145 cury, N-benzyl-D-glucamine dithiocarbamate, glucosuria, atractyloside, nephrotoxin, proximal 2,3-dimercaptopropanol, biliary and urinary tubular toxin, hypoglycemia, hypoxemia, excretion, intestinal reabsorption, 157 dogs, 259 dendritic cells, contact sensitization, local lymph glutamine transaminase K, nephrotoxicity, halo- node responses, percutaneous absorption, genated alkenes, hexachloro-1,3-butadiene, sodium lauryl sulphate, 2,4-dinitrochloro- N-acetyl-S-(1,2,3,4,4-pentachloro-1,3-butadi- benzene, 181 enyl)-L-cysteine, cysteine conjugate #-lyase, 2,3-dimercaptopropanol, chemical form, inor- enzyme induction and inhibition, 133 ganic mercury, N-benzyl-D-glucamine dithio- glutathione, cadmium nephrotoxicity, glomer- carbamate, D-penicillamine, biliary and urin- ulus, mesangial cell, metallothionein, 145 ary excretion, intestinal reabsorption, 157 glutathione, cadmium, nickel, toxicity, cyto- 2,4-dinitrochlorobenzene, contact sensitization, skeleton, protein sulfhydryls, 65 local lymph node responses, dendritic cells, percutaneous absorption, sodium lauryl sulphate, 181 halogenated alkenes, L-cysteine conjugates, mer- disodium arsenate, arsenic, gallbladder, chole- capturic acids, nephrotoxicity, rat renal slice, cystitis, rainbow trout, 233 281 DNA strand breaks, chromium, cytotoxicity, un- halogenated alkenes, nephrotoxicity, hexachloro- scheduled DNA synthesis (UDS), hepatocyte, 1,3-butadiene, N-acetyl-S-(1,2,3,4,4-pentach- 171 loro-1,3-butadienyl)-L-cysteine, cysteine con- dogs, atractyloside, nephrotoxin, proximalular jugate B-lyase, glutamine transaminase K, toxin, hypoglycemia, hypoxemia, glucosuria, enzyme induction and inhibition, 133 259 haloperidol, lipoperoxidation, kidney homo- dopamine receptor, organic solvent, apomor- genates, lactic acid, iron, 249 phine, N-propylnorapomorphine, locomotion, hepatic peroxisome proliferation, chlorinated spatial learning, 223 paraffins, thyroid, 81 doxorubicin, mitoxantrone, cardiotoxicity, lipo- hepatocyte, chromium, cytotoxicity, unscheduled peroxidation, chemiluminescence, oxidative DNA synthesis (UDS), DNA strand breaks, stress, 31 171 267 hepatotoxicity, taurine, B-alanine, carbon tetra- sodium lauryl sulphate, 2,4-dinitrochloro- chloride, liver, increased susceptibility, 7 benzene, 181 hepatotoxicity, taurine, liver, urinary marker, locomotion, organic solvent, apomorphine, N- prediction of susceptibility, 1 propylnorapomorphine, dopamine receptor, hexachloro-1,3-butadiene, nephrotoxicity, halo- spatial learning, 223 genated alkenes, N-acetyl-S-(1,2,3,4,4-penta- lung tumors, N-nitrosodiethylamine (DEN), chloro-1,3-butadienyl)-L-cysteine, cysteine Syrian golden hamster, ozone, cell prolifera- conjugate 6-lyase, glutamine transaminase K, tion, tumor modulation, 193 enzyme induction and inhibition, 133 hypoglycemia, hypoxemia, atractyloside, neph- a-melanocyte stimulating hormone (MSH), rotoxin, proximal tubular toxin, glucosuria, pigmentation, fetal development, 91 dogs, 259 mercapturic acids, halogenated alkenes, L- hypoxemia, atractyloside, nephrotoxin, proximal cysteine conjugates, nephrotoxicity, rat renal tubular toxin, glucosuria, dogs, hypoglycemia, slice, 281 259 mesangial cell, cadmium nephrotoxicity, glomerulus, glutathione, metallothionein, 145 metallothionein, cadmium nephrotoxicity, glo- immunotoxicity, C57BL/6 mice, coplanar PCBs, merulus, mesangial cell, glutathione, 145 teratogenicity, 123 mitoxantrone, doxorubicin, cardiotoxicity, lipo- increased susceptibility, taurine, B-alanine, car- peroxidation, chemiluminescence, oxidative bon tetrachloride, hepatotoxicity, liver, 7 stress, 31 inorganic mercury, chemical form, N-benzyl-p- mixtures, risk assessment, porphyria, relative glucamine dithiocarbamate, D-penicillamine, potency, carcinogenicity, threshold, chlorin- 2,3-dimercaptopropanol, biliary and urinary ated dibenzo-p-dioxins, 39 excretion, intestinal reabsorption, 157 muscarinic receptors, neurotoxicity, 1,1,1- interaction, neurotoxicity, 1,1,1-trichloro-2,2- trichloro-2,2-bis(p-chlorophenyl)-ethane bis(p-chlorophenyl)-ethane (DDT), pyreth- (DDT), pyrethroid, interaction, behaviour, 21 roid, behaviour, muscarinic receptors, 21 intestinal reabsorption, chemical form, inorganic N-propylnorapomorphine, organic solvent, mercury, N-benzyl-D-glucamine dithiocarba- apomorphine, dopamine receptor, locomo- mate, D-penicillamine, 2,3-dimercaptopropa- tion, spatial learning, 223 nol, biliary and urinary excretion, 157 N-nitrosodiethylamine (DEN), Syrian golden iron, lipoperoxidation, kidney homogenates, lac- hamster, lung tumors, ozone, cell prolifera- tic acid, haloperidol, 249 tion, tumor modulation, 193 nephrotoxicity, halogenated alkenes, hexachloro- kidney homogenates, lipoperoxidation, lactic 1,3-butadiene, N-acetyl-S-(1,2,3,4,4-pentach- acid, iron, haloperidol, 249 loro-1,3-butadienyl)-L-cysteine, cysteine con- L-cysteine conjugates, halogenated alkenes, mer- jugate B-lyase, glutamine transaminase K, capturic acids, nephrotoxicity, rat renal slice, enzyme induction and inhibition, 133 281 nephrotoxicity, halogenated alkenes, L-cysteine conjugates, mercapturic acids, rat renal slice, lactic acid, lipoperoxidation, kidney homogen- 281 ates, iron, haloperidol, 249 nephrotoxin, atractyloside, proximal tubular lipoperoxidation, doxorubicin, mitoxantrone, toxin, hypoglycemia, hypoxemia, glucosuria, cardiotoxicity, chemiluminescence, oxidative dogs, 259 stress, 31 neurotoxicity, _1,1,1-trichloro-2,2-bis(p-chloro- lipoperoxidation, kidney homogenates, lactic phenyl)-ethane (DDT), pyrethroid, interac- acid, iron, haloperidol, 249 tion, behaviour, muscarinic receptors, 21 liver, taurine, B-alanine, carbon tetrachloride, nickel, cadmium, toxicity, cytoskeleton, protein hepatotoxicity, increased susceptibility, 7 sulfhydryls, glutathione, 65 liver, taurine, hepatotoxicity, urinary marker, prediction of susceptibility, 1 organic solvent, apomorphine, N-propylnorapo- local lymph node responses, contact sensitiza- morphine, dopamine receptor, locomotion, tion, dendritic cells, percutaneous absorption, spatial learning, 223 268 oxidative stress, doxorubicin, mitoxantrone, car- sodium lauryl sulphate, contact sensitization, diotoxicity, lipoperoxidation, chemilumines- local lymph node responses, dendritic cells, cence, 31 percutaneous absorption, 2,4-dinitrochloro- ozone, N-nitrosodiethylamine (DEN), Syrian benzene, 181 golden hamster, lung tumors, cell prolifera- spatial learning, organic solvent, apomorphine, tion, tumor modulation, 193 N-propylnorapomorphine, dopamine receptor, locomotion, 223 Syrian golden hamster, N-nitrosodiethylamine P-450 1A1, 2,3,7,8-tetrachlorodibenzo-p-dioxin, (DEN), lung tumors, ozone, cell proliferation, phosphoenolpyruvate carboxykinase, enzyme tumor modulation, 193 activity, PEPCK mRNA, tryptophan 2,3- taurine, #-alanine, carbon _ tetrachloride, dioxygenase, 295 hepatotoxicity, liver, increased susceptibility, PEPCK mRNA, 2,3,7,8-tetrachlorodibenzo-p- 7 dioxin, phosphoenolpyruvate carboxykinase, enzyme activity, tryptophan 2,3-dioxygenase, taurine, liver, hepatotoxicity, urinary marker, P-450 1A1, 295 prediction of susceptibility, 1 percutaneous absorption, contact sensitization, teratogenicity, C57BL/6 mice, coplanar PCBs, local lymph node responses, dendritic cells, immunotoxicity, 123 sodium lauryl sulphate, 2,4-dinitrochloro- 2,3,7,8-tetrachlorodibenzo-p-dioxin, benzene, 181 phosphoenolpyruvate carboxykinase, enzyme phosphoenolpyruvate carboxykinase, 2,3,7,8- activity, PEPCK mRNA, tryptophan 2,3- tetrachlorodibenzo-p-dioxin, enzyme activity, dioxygenase, P-450 1A1, 295 PEPCK mRNA, tryptophan 2,3-dioxygenase, 3,7,8-tetrachlorodibenzo-p-dioxin, thymocytes, P-450 1A1, 295 apoptosis, arylhydrocarbon (Ah) receptor, 103 pigmentation, a-melanocyte stimulating hor- threshold, risk assessment, porphyria, mixtures, mone (MSH), fetal development, 91 relative potency, carcinogenicity, chlorinated porphyria, risk assessment, mixtures, relative dibenzo-p-dioxins, 39 potency, carcinogenicity, threshold, chlorin- thymocytes, apoptosis, 2,3,7,8-tetrachlorodi- ated dibenzo-p-dioxins, 39 benzo-p-dioxin, arylhydrocarbon (Ah) recep- prediction of susceptibility, taurine, _ liver, tor, 103 hepatotoxicity, urinary marker, | thyroid, chlorinated paraffins, hepatic peroxi- proximal tubular toxin, atractyloside, nephro- some proliferation, 81 toxin, hypoglycemia, hypoxemia, glucosuria, toxic oil syndrome, fatty acid anilides, endothe- dogs, 259 lial cells, eicosanoids, arachidonic acid, 51 protein sulfhydryis, cadmium, nickel, toxicity, toxicity, cadmium, nickel, cytoskeleton, protein cytoskeleton, glutathione, 65 sulfhydryls, glutathione, 65 pyrethroid, neurotoxicity, 1,1,1-trichloro-2,2- 1,1,1-trichloro-2,2-bis(p-chlorophenyl)-ethane bis(p-chlorophenyl)-ethane (DDT), interac- (DDT), neurotoxicity, pyrethroid, interaction, tion, behaviour, muscarinic receptors, 21 behaviour, muscarinic receptors, 21 tryptophan 2,3-dioxygenase, 2,3,7,8-tetrachlorodibenzo-p-dioxin, phosphoenolpyruvate car- rainbow trout, arsenic, disodium arsenate, boxykinase, enzyme activity, PEPCK mRNA, gallbladder, cholecystitis, 233 P-450 1A1, 295 rat renal slice, halogenated alkenes, L-cysteine tumor modulation, AN-nitrosodiethylamine conjugates, mercapturic acids, nephrotoxicity, (DEN), Syrian golden hamster, lung tumors, 281 ozone, cell proliferation, 193 relative potency, risk assessment, porphyria, mixtures, carcinogenicity, threshold, chlorinated unscheduled DNA synthesis (UDS), chromium, dibenzo-p-dioxins, 39 cytotoxicity, DNA strand breaks, hepatocyte, risk assessment, porphyria, mixtures, relative 171 potency, carcinogenicity, threshold, urinary marker, taurine, liver, hepatotoxicity, chlorinated dibenzo-p-dioxins, 39 prediction of susceptibility, 1 Toxicology, 77 (1993) 269 Elsevier Scientific Publishers Ireland Ltd. TOXICOLOGY AUTHOR INDEX Volume 77 (1993) Abraham, M. 103 Greim, H. 39 Piriou, A. 249 Adachi, T. 157 Gustafsson, J.—8f-. 223 Plopper, C.G. 193 Ahlbom, J. 21 Pontcharraud, R. 249 Arnaiz, S.L. 31 Hilton, J. 181 Holloway, H. 91 Roelandt, L. 133 Basketter, D.A. 181 Horvath, G. 115 Roth, W.L. 39 Beer, D.G. 295 Howie, L. 123 Rozman, K. 295 Bettger, W.J. 233 Huguet, F. 249 Rozman, K. 39 Binks, S.P. 171 Johansson, U. 21 Safe, S. 123 de Castellarnau, C. 51 Johnson, P. 91 Scales, M.D.C. 1 Chin, T.A. 145 Scales, M.D.C. 7 Chipman, J.K. 171 Kelly, D.P. 205 Schimke, I. 115 Chou, I.-N. 65 Kimber, I. 181 Schofield, M. 133 Cockell, K.A. 233 King, L.J. 133 Scholes, E.W. 181 Commandeur, J.N.M. 281 Kiyozumi, M. 157 Scott, R.C. 181 Coutts, C.T. 81 Koechel, D.A. 259 Shimada, H. 157 Cumberbatch, M. 181 Kojima, S. 157 Spainhour, C.B. 123 Krejci, M.E. 259 Stahl, B.U. 295 Kurl, R.N. 103 Stahl, B.U. 39 David, M. 115 Stijntjes, G.J. 281 David, M. 133 Lagunas, C. 51 Dawson, B.V. 91 Lee, K.P. 205 Tallineau, C. 249 Dearman, R.J. 181 Levy, L.S. 171 te Koppele, J.M. 281 Dorr, R.T. 91 Li, W. 65 Templeton, D.M. 145 Doull, J. 39 Li, X.M. 223 Timbrell, J.A. 1 Llesuy, S. 31 Timbrell, J.A. 7 Elcombe, C.R. 81 Lock, E.A. 133 Turton, J.A. 1 von Euler, G. 223 Lopez, S. 51 Turton, J.A. 7 Eriksson, P. 21 MacFarlane, M. 133 Vermeulen, N.P.E. 281 Mayura, K. 123 Vila, L. 51 Fauconneau, B. 249 McGuinness, S. 281 Ford, C.A. 91 Mueller, M.M. 115 Waterfield, C.J. 1 Fredriksson, A. 21 Waterfield, C.J. 7 Fukudome, S. 157 Nagy, I. 115 Weber, L.W.D. 295 Funakoshi, T. 157 Wilson, D.W. 193 Fuxe, K. 223 Olnes, M.J. 103 Witshci, H. 193 Ogren, S.-O. 223 Wyatt, I. 81 Gandolfi, A.J. 281 Gao, M. 171 Parker, N. 133 Yasutake, A. 157 Phillips, T.D. 123 Gibson, G.G. 133 Pich, I. 51 Zhao, Y. 65 Goldfarb, P.S. 133