Toxicology 1991: Vol 69 Table of Contents

2 Pages·1991·0.66 MB·English

Toxicology, 69 (1991) 355-356
Elsevier Scientific Publishers Ireland Ltd.
TOXICOLOGY
VOLUME CONTENTS
Volume 69 (1991)
The cerium-induced liver injury and oxidative drug metabolism in DBA/2 and C57BL/6 mice (The cerium-induced
morphological and enzymatic changes are markedly different in both mouse strains)
by P. Arvela, H. Kraul, F. Stenback and O. Pelkonen Oulu, Finland)
Effects of organic solvent vehicles on the viability and morphology of isolated perfused porcine skin (Vehicle
effects need to be studied carefully in any model of cutaneous research)
by J.R. King and N.A. Monteiro-Riviere (Raleigh, NC)
Neonatal exposure to 3,3’,4,4’-tetrachlorobiphenyl: changes in spontaneous behaviour and cholinergic muscarinic
receptors in the adult mouse (Locomotional behaviour is affected while there seems to be only a small effect
on central receptors)
by P. Eriksson, U. Lundkvist and A. Fredriksson (Uppsala, Sweden)
Dermal intoxication of mice with bis(2-chloroethyl)sulphide and the protective effect of flavonoids
(Flavonoids moderately protect against dermally applied sulphur mustard)
by R. Vijayaraghavan, K. Sugendran, S.C. Pant, K. Husain and R.C. Malhotra (Gwalior, India)
Regional effects on the cerebral concentration of noradrenaline, serotonin and dopamine in suckling rats after
a single dose of lindane (The weak convulsive lindane increases monoaminergic activity age- and region-relatedly)
by S. Rivera, C. Sanfeliu, C. Sufiol and E. Rodriguez-Ferré (Barcelona, Spain)
Lack of induction of hepatic DNA damage on long-term administration of peroxisome proliferators in male F-344
rats (DNA changes were only found in tumor-bearing livers)
by H. Tamura, T. lida, T. Watanabe and T. Suga (Tokyo, Japan)
Cadmium toxicity: unique cytoprotective properties of alpha tocopheryl succinate in hepatocytes (Unesterified
alpha tocopherol does not protect hepatocytes against Cd injury, but alpha tocopherol succinate protects against
injury and lipid peroxidation)
by M.W. Fariss (Richmond, VA)
Reactive oxygen species and non-peroxidative mechanisms of cocaine-induced cytotoxicity in rat hepatocyte cultures
(Iron dependent peroxidation reactions lead to cell injury)
by C.R. G6ldlin and U.A. Boelsterli (Schwerzenbach, Switzerland)
Protective effects of dextran sulfate and polyvinyl sulfate against acute toxicity of paraquat in mice (The
protective agents reduce gastrointestinal transit time and inhibit paraquat absorption)
by S. Kojima, Y. Miyazaki, T. Honda, M. Kiyozumi, H. Shimada and T. Funakoshi (Kumamoto, Japan)
Cytoprotective effect of reduced glutathione in arsenical-induced endothelial cell injury (Intracellular GSH and
PG I 2 protect cultured cells against the cytotoxicity of trivalent arsenicals)
by W.-C. Chang, S.-H. Chen, H.-L. Wu, G.-Y. Shi, S. Murota and I. Morita (Taiwan, China) and Tokyo,
101-110
Effect of in vitro treatment of rat hepatocytes with selenium, and/or cadmium on cell viability, glucose output
and cellular glutathione (Selenium protects partially hepatocytes against the toxic effects of Cd on hepatocytes)
by R.R. Bell, V.K. Nonavinakere, M.R.I. Soliman and J.L. Early II (Tallahassee, FL) 111-119
Distal nephrotoxicity of cisplatin demonstrated by urinary kallikrein excretion and morphological study in rats
(Urinary kallikrein is a useful marker for distal tubular damage)
by G. Bompart, C. Orfila and J.-P. Girolami (Toulouse, France) 121-132
Effects of acute nickel toxicity upon plasma and liver metal homeostasis as a function of sex (The injection of
nickel seems to affect the tissue concentrations of other metals and metal-related proteins)
by J. Cartana, L. Arola and A. Mas (Tarragona, Spain) 133-141
Induction of metallothionein in mouse liver by valproic acid (While valproic acid induces hepatic metallothionein,
Cu and Zn levels do not change)
by M. Kaji and H. Mikawa (Kyoto, Japan) 143-149
356
Acute effects of the D-isomer of S-(1,2-dichlorovinyl)cysteine on renal function and ultrastructure in the
pentobarbital-anesthetized dog: Site-specific toxicity involving the S, and S, cells of the proximal tubule
(Although slightly less potent, the D-isomer produces similar morphologic and functional signs of kidney damage
as does the L-isomer)
by M.E. Krejci, R.E. Ridgewell and D.A. Koechel (Toledo, OH) 151-164
Acute effects of the Bowman-Birk protease inhibitor in mice (Demonstration of protease inhibition in lung in vivo)
by V.I.C. Oreffo, P.C. Billings, A.R. Kennedy and H. Witschi (Davis, CA and Philadelphia, PA) 165-176
Nature of Cd and Hg effects on epithelial amino acid transport in vivo and role of chelators (Hg produces an
immediate inhibition of amino acid transport in the kidneys, whereas after Cd, effects develop more slowly)
by E.C. Foulkes (Cincinnati, OH) 177-185
6-Alkyl-1,3,8-trichlorodibenzofurans as antiestrogens in female Sprague—Dawley rats (A correlation between an-
tiestrogenic potencies and Ah receptor binding was found)
by B. Astroff and S. Safe (College Station, TX) 187-197
Effect of benzyl viologen on the fatty acid composition of rat liver (Chronic treatment lowers body weight, in-
creases hepatic lipids and changes their patterns)
by V. Ruiz-Gutierrez, F.J.G. Muriana and F.J. Quintero (Sevilla, Spain) 199-207
Draining lymph node cell activation in guinea pigs: Comparisons with the murine local lymph node assay (Skin
sensitizing chemicals stimulate thymidine uptake by lymph node cells not only in mice but also in guinea pigs)
by T. Maurer and I. Kimber (Basel, Switzerland and Macclesfield, U.K.) ..............ccccecceeeeccceeeeeeeeeeeeeeeeeenees 209-218
Review Article
A review of 2,3,7,8-tetrachlorodibenzo-p-dioxin-induced changes in immunocompetence: 1991 update (An analysis
of available data and of future research needs)
by M.P. Holsapple, N.K. Snyder, S.C. Wood and D.L. Morris (Richmond, VA) 219-255
Influence of chlordimeform on alpha-adrenergic receptor-associated mechanisms of hormonal regulation in the
rat: Pituitary and adrenocortical secretion (Chlordimeform appears to interfere with a regulatory signal mediated
by alpha-adrenergic receptor-associated activity)
by T.E. Stoker, JM. Goldman, R.L. Cooper and W.K. McElroy (Research Triangle Park, NC) 257-268
The effect of age of exposure on lead-induced testicular toxicity (Prepubertal rats may be less sensitive to lead-
induced testicular toxicity than are older animals)
by R.Z. Sokol and N. Berman (Torrance, CA) 269-278
Hepatic glutathione suppression by the a-adrenoreceptor stimulating agents phenylephrine and clonidine (Adrenergic
agents may disrupt hepatic glutathione homeostasis and impair detoxification of certain compounds)
by R.D. Harbison, R.C. James and S.M. Roberts (Gainesville, FL) 279-290
Reproductive and developmental toxicity studies of pyridostigmine bromide in rats (Fertility or reproductive
performance were not affected and no drug effects were observed in the offspring)
by B.S. Levine and R.M. Parker (Chicago, IL and Jefferson, AR) 291-300
A new method for delivering alkanes to mammalian cells: preparation and preliminary characterization of an
inclusion complex between 6-cyclodextrin and pristane (2,6,10,14-tetramethylpentadecane) (Validation of the
methodology used to deliver alkanes into cells in vitro)
by S. Janz and E. Shacter (Bethesda, MD) 301-315
An explanation for strain and sex differences in renal uptake of methylmercury in mice (Differences in renal
uptake of methylmercury correlate with hepatic or plasma glutathione levels)
by T. Tanaka, A. Naganuma, K. Kobayashi and N. Imura (Tokyo, Japan) 317-329
Organophosphate poisoning: a method to test therapeutic effects of oximes other than acetylcholinesterase
reactivation in the rat (The non-enzyme-reactivating oxime HI-6 improves neuromuscular transmission possiby
by interference with acetylcholine receptors)
by R.W. Busker, J.J. Zijlstra, H.J. van der Wiel, B.P.C. Melchers and H.P.M. van Helden (Rijswijk, The
Netherlands) 331-344
Contents of journals relating to Toxicology 345-348
Subject Index Volume 69 349-352
Author Index Volume 69 353-354
Contents Volume 69 355-356