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TOXICITY OF NANOMATERIALS: environmental and healthcare applications PDF

259 Pages·2019·32.832 MB·English
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Toxicity of Nanomaterials Toxicity of Nanomaterials Environmental and Healthcare Applications Edited by Prof. Suresh C. Pillai Nanotechnology and Bio-Engineering Division, Faculty of Science, Institute of Technology, Sligo, Ireland Dr. Yvonne Lang Nanotechnology and Bio-Engineering Division, Faculty of Science, Institute of Technology, Sligo, Ireland CRC Press Taylor & Francis Group 6000 Broken Sound Parkway NW, Suite 300 Boca Raton, FL 33487-2742 © 2019 by Taylor & Francis Group, LLC CRC Press is an imprint of Taylor & Francis Group, an Informa business No claim to original U.S. Government works Printed on acid-free paper International Standard Book Number-13: 978-1-138-54430-7 (Hardback) This book contains information obtained from authentic and highly regarded sources. Reasonable efforts have been made to publish reliable data and information, but the author and publisher cannot assume responsibility for the validity of all materials or the consequences of their use. The authors and publishers have attempted to trace the copyright holders of all material reproduced in this publication and apologize to copyright holders if permission to publish in this form has not been obtained. If any copyright material has not been acknowledged please write and let us know so we may rectify in any future reprint. Except as permitted under U.S. Copyright Law, no part of this book may be reprinted, reproduced, transmitted, or utilized in any form by any electronic, mechanical, or other means, now known or hereafter invented, including photocopying, microfilming, and recording, or in any information storage or retrieval system, without written permission from the publishers. For permission to photocopy or use material electronically from this work, please access www.copyright.com (http://www. copyright.com/) or contact the Copyright Clearance Center, Inc. (CCC), 222 Rosewood Drive, Danvers, MA 01923, 978-750- 8400. CCC is a not-for-profit organization that provides licenses and registration for a variety of users. For organizations that have been granted a photocopy license by the CCC, a separate system of payment has been arranged. Trademark Notice: Product or corporate names may be trademarks or registered trademarks, and are used only for identification and explanation without intent to infringe. Visit the Taylor & Francis Web site at http://www.taylorandfrancis.com and the CRC Press Web site at http://www.crcpress.com Contents Editors ......................................................................................................................vii Contributors .............................................................................................................ix 1 Cytotoxicology Studies of 2-D Nanomaterials .........................................................1 Priyanka Ganguly, Ailish Breen, and Suresh C. Pillai 2 Effects of Nanocrystal Morphologies on Cytotoxicity ...................................................27 Aine M. Whelan 3 Environmental and Cytotoxicity Risks of Graphene Family Nanomaterials .............49 Saoirse Dervin 4 Toxicology Studies of Semiconductor Nanomaterials: Environmental Applications ......................................................................................................95 T. P. Nisha, Meera Sathyan, M. K. Kavitha, and Honey John 5 Toxicity Analysis of Ag and Au Nanoparticles .....................................................121 Sami Rtimi 6 Designing Smart Nanotherapeutics ....................................................................139 A. Joseph Nathanael, Tae Hwan Oh, and Vignesh Kumaravel 7 Identifying Nanotoxicity at the Cellular Level Using Electron Microscopy .............163 Kerry Thompson, Alanna Stanley, Emma McDermott, Alexander Black, and Peter Dockery 8 Ecotoxicology of Nanoparticles ..........................................................................191 Iain Murray and Andy Fogarty 9 Lab-on-a-Chip-Based Devices for Rapid and Accurate Measurement of Nanomaterial Toxicity .......................................................................................215 Mehenur Sarwar, Amirali Nilchian, and Chen-zhong Li Index ......................................................................................................................243 v Editors Suresh C. Pillai obtained his PhD from Trinity College Dublin and then conducted his postdoctoral research at California Institute of Technology (Caltech), USA. Upon completion of this appointment he returned to Trinity College Dublin in April 2004 as a Research Fellow before joining CREST-DIT as a Senior Scientist. He joined IT Sligo in 2013 as a senior lecturer in nanotechnology and currently heads the Nanotechnology and Bio-Engineering Research Group. He is an elected fellow of the UK’s Royal Microscopical Society (FRMS) and the Institute of Materials, Minerals and Mining (FIMMM). Prof. Pillai also completed an executive MBA from Dublin City University in 2009. He was responsible for acquiring more than €5 million direct R&D funding. He was awarded the 2019 ‘Boyle-Higgins’ award by the Institute of Chemistry Ireland and received the ‘Industrial Technologies Award 2011’ for licensing functional coatings to Irish companies. He was also the recipient of the ‘Hothouse Commercialisation Award 2009’ from the Minister of Science, Technology and Innovation and the ‘Enterprise Ireland Research Commercialization Award 2009’. He is an editor for the journal Environmental Science and Pollution Research (ESPR, Springer) and an Editororial Board Member for the Chemical Engineering Journal and Applied Catalysis B (Elsevier). Yvonne Lang obtained her PhD from the National University of Ireland, Galway in 2014. Her doctoral research investigated the use of diatoms to fabricate polymeric structures with a defined geometry. Work emanating from this research has been published in peer-reviewed journals and has been presented at several key international conferences. She received the European Society for Biomaterials Julia Polak Educational Doctorate Award for her doctoral research. Dr. Lang’s postdoctoral research focussed on varying aspects of nanoparticles including investigation of both therapeutic and environmental appli- cations of nanoparticles, quantification of nanoparticles in biological samples and exploration of biore- mediation approaches to detect and capture nanoparticles in environmental samples. Dr. Lang is currently a lecturer in chemistry at the Institute of Technology, Sligo Ireland. She is a member of both the Nanotechnology and Bio-Engineering Research Division and the Centre for Environmental Research, Innovation and Sustainability at IT Sligo. She is a committee member of the Microscopy Society of Ireland and a past committee member of the Environmental Scientists Association of Ireland. She is actively involved in the co-ordination and delivery of outreach events to promote scientific activities to the public. Her research interests include: (1) investigation of diatom cultures and diatom products as decontamination agents for removal of organic pollutants from water; (2) interactions of microorganisms and microplastics and (3) impact of outreach activities on attitudes to habitat, health and well-being. vii Contributors Alexander Black Peter Dockery Division of Anatomy Division of Anatomy School of Medicine School of Medicine College of Medicine, Nursing and Health College of Medicine, Nursing and Health Sciences Sciences National University of Ireland Galway National University of Ireland Galway Galway, Ireland and Centre for Microscopy and Imaging National University of Ireland Galway Ailish Breen Galway, Ireland Nanotechnology and Bio-engineering Research Group Department of Environmental Science Andy Fogarty School of Science Department of Life and Physical Sciences Institute of Technology Sligo Athlone Institute of Technology and Athlone, Ireland Centre for Precision Engineering, Materials and Manufacturing Research (PEM) Priyanka Ganguly Institute of Technology Sligo Nanotechnology and Bio-engineering Research Sligo, Ireland Group Department of Environmental Science Saoirse Dervin School of Science Nanotechnology and Bio-Engineering Research Institute of Technology Sligo Group and Department of Environmental Science Centre for Precision Engineering, Materials and Institute of Technology Sligo Manufacturing Research (PEM) and Institute of Technology Sligo Centre for Precision Engineering, Materials and Sligo, Ireland Manufacturing Research (PEM) Institute of Technology Sligo Sligo, Ireland ix

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