The Textbook of Nanoneuroscience and Nanoneurosurgery

585 Pages·2013·39.105 MB·English

by  Babak Kateb, John D. Heiss

NEUROSCIENCE The Textbook of
Nanoneuroscience
Kateb • Heiss and
The Textbook of
Nanoneuroscience Nanoneurosurgery
and
Nanoneurosurgery
Nanoneuroscience, nanoneurosurgery, and nanobioelectronic N
shave the potential to revolutionize medicine and improve
a
the prevention, diagnosis, and treatment of neurological disorders over the next several n
decades. The Textbook of Nanoneuroscience and Nanoneurosurgery presents a o
n
state-of-the-art review of the field, providing current information about nanoplatforms and
e
their use in neurosurgery, neurology, neuroscience, and neuroradiology.
u
r
o
The text also reviews the latest regulatory guidelines that influence the translation of
s
nanotechnological research from the laboratory to the clinic, as well as the most recent
c
information on biodevices and pharmaceutical spinoffs. It highlights presidential and i
e
congressional initiatives and programs that may significantly impact the field in the near n T
h
future. Chapters discuss the latest science and technologies, which are applied to c
e
e
diagnosis and treatment of neurological disorders, as well as regulatory issues that impact T
e
product development. a x
n t
d b
o
This volume describes advances that have already been translated to the clinic or hold N o
k
significant promise for future application in nanoneurosurgery, and their potential impact a
o
n f
is addressed throughout the book. A full-color text, it contains contributions by more than
o
120 researchers, original and descriptive illustrations, and more than 3,000 references.
n
Offering broad coverage of nanotechnological applications in diverse areas and addressing e
FDA regulation and healthcare policy, this book provides a foundation of ideas and methods u
r
for scientists and physicians to devise successful, less invasive procedures for future
o
treatment of nervous system disorders. s
u
This book is endorsed by Society for Brain Mapping and Therapeutics (www.WorldBrainMapping.org), r
g
Brain Mapping Foundation, and National Center for NanoBioElectronics. A portion of the proceeds of
e
this book will be donated to Brain Mapping Foundation to fund nanoneurosurgery and nanobioelectronic
r
research projects. For more information, please visit www.brainmappingfoundation.org. y
Endorsed by
K12237
Edited by
Babak Kateb • John D. Heiss
6000 Broken Sound Parkway, NW
Suite 300, Boca Raton, FL 33487
711 Third Avenue
BRAINMAPPING
New York, NY 10017
an informa business 2 Park Square, Milton Park w w w . c r c p r e s s . c o m FOUNDATION
www.crcpress.com Abingdon, Oxon OX14 4RN, UK

The Textbook of
Nanoneuroscience
and
Nanoneurosurgery

The Textbook of
Nanoneuroscience
and
Nanoneurosurgery
Edited by
Babak Kateb • John D. Heiss
Boca Raton London New York
CRC Press is an imprint of the
Taylor & Francis Group, an informa business
CRC Press
Taylor & Francis Group
6000 Broken Sound Parkway NW, Suite 300
Boca Raton, FL 33487-2742
© 2014 by Taylor & Francis Group, LLC
CRC Press is an imprint of Taylor & Francis Group, an Informa business
No claim to original U.S. Government works
Version Date: 20130606
International Standard Book Number-13: 978-1-4398-4942-2 (eBook - PDF)
This book contains information obtained from authentic and highly regarded sources. While all reasonable efforts have been
made to publish reliable data and information, neither the author[s] nor the publisher can accept any legal responsibility or
liability for any errors or omissions that may be made. The publishers wish to make clear that any views or opinions expressed
in this book by individual editors, authors or contributors are personal to them and do not necessarily reflect the views/opinions
of the publishers. The information or guidance contained in this book is intended for use by medical, scientific or health-care
professionals and is provided strictly as a supplement to the medical or other professional’s own judgement, their knowledge
of the patient’s medical history, relevant manufacturer’s instructions and the appropriate best practice guidelines. Because of
the rapid advances in medical science, any information or advice on dosages, procedures or diagnoses should be independently
verified. The reader is strongly urged to consult the drug companies’ printed instructions, and their websites, before adminis-
tering any of the drugs recommended in this book. This book does not indicate whether a particular treatment is appropriate
or suitable for a particular individual. Ultimately it is the sole responsibility of the medical professional to make his or her own
professional judgements, so as to advise and treat patients appropriately. The authors and publishers have also attempted to trace
the copyright holders of all material reproduced in this publication and apologize to copyright holders if permission to publish
in this form has not been obtained. If any copyright material has not been acknowledged please write and let us know so we may
rectify in any future reprint.
Except as permitted under U.S. Copyright Law, no part of this book may be reprinted, reproduced, transmitted, or utilized in any
form by any electronic, mechanical, or other means, now known or hereafter invented, including photocopying, microfilming,
and recording, or in any information storage or retrieval system, without written permission from the publishers.
For permission to photocopy or use material electronically from this work, please access www.copyright.com (http://www.copy-
right.com/) or contact the Copyright Clearance Center, Inc. (CCC), 222 Rosewood Drive, Danvers, MA 01923, 978-750-8400.
CCC is a not-for-profit organization that provides licenses and registration for a variety of users. For organizations that have been
granted a photocopy license by the CCC, a separate system of payment has been arranged.
Trademark Notice: Product or corporate names may be trademarks or registered trademarks, and are used only for identifica-
tion and explanation without intent to infringe.
Visit the Taylor & Francis Web site at
http://www.taylorandfrancis.com
and the CRC Press Web site at
http://www.crcpress.com
Dedication
We dedicate this textbook to our spouses, parents, family, mentors, students, and
medical and scientific colleagues. We appreciate their support for our efforts.
© 2010 Taylor & Francis Group, LLC
On the Cover
Front cover: Depicts the current invasive neurosurgical approach. Comparatively, in the future
non- or minimally-invasive nanoneurosurgery will be much more individualized, targeted therapy
performed by smart self-assembling molecules and nanoplatforms. (Pictures are courtesy of Babak
Kateb and Jean Paul Allain.)
Back cover: A view of the cortical surface of a college student with new-onset partial motor sei-
zures affecting the left face and findings of a right frontal lobe mass on MRI. An image-guided right
frontotemporal craniotomy was performed and the dura was opened. The inferoposterior part of the
frontal lobe is seen on the left (anterior anatomical) side of the photograph. The superior temporal
gyrus is seen on the top (inferior anatomical) portion of the photograph. The Sylvian fissure sepa-
rates the frontal and temporal lobes. Note the paleness and expansion of the frontal lobe gyrus in
the center of the exposure that contains the tumor. No seizures occurred after complete excision of
a dysembryoplastic neuroepithelial tumor. (Picture courtesy of John D. Heiss.)
vi
© 2010 Taylor & Francis Group, LLC
Contents
Mission Statements ...........................................................................................................................xi
Preface............................................................................................................................................xiii
Editors ..............................................................................................................................................xv
Contributors ...................................................................................................................................xvii
Chapter 1 From Nanotechnology to Nanoneuroscience/Nanoneurosurgery and
Nanobioelectronics: A Historical Review of Milestones .............................................1
Vicky Yamamoto, Giancarlo Suffredini, Shouleh Nikzad, Michael E. Hoenk,
Miriam S. Boer, Charlie Teo, John D. Heiss, and Babak Kateb
Chapter 2 Nanoneurology and Nanoneurosurgery .....................................................................29
Geoffrey S. F. Ling, Robbin Miranda, and Gill Pratt
Chapter 3 Nanopolymers and Nanoconjugates for Central Nervous System Diagnostics
and Therapies .............................................................................................................39
Giancarlo Suffredini and Lucien M. Levy
Chapter 4 Micelles and Liposomes: Lipid Nanovehicles for Intracerebral Drug Delivery ........51
Massimo S. Fiandaca and Krystof S. Bankiewicz
Chapter 5 Peptide and Protein-Based Nanoparticles ..................................................................65
Ayaz M. Khawaja and John D. Heiss
Chapter 6 Endohedral Metallofullerenes, Iron Oxide Agents, and Gold Nanoparticles for
Brain Imaging ............................................................................................................81
Martina A. McAteer and Robin P. Choudhury
Chapter 7 Carbon Nanoplatforms and Their Application for Neurological Disorders ...............95
Houman Badrzadeh, Peyman Tashkandi, Michelle Knosp, and Babak Kateb
Chapter 8 Dendrimers ...............................................................................................................107
Ayaz M. Khawaja and John D. Heiss
Chapter 9 Ligand-Based Targeting of Therapeutic and Imaging Agents for Cancer ...............125
Qimeng Quan, Seulki Lee, and Xiaoyuan Chen
vii
© 2010 Taylor & Francis Group, LLC
viii Contents
Chapter 10 Immune-Based Targeting in Cancer ........................................................................141
Dwain K. Irvin, Chirag G. Patil, and Keith L. Black
Chapter 11 Directed Drug Convection Using Magnetic Nanoparticles as Therapeutic
Carriers: Meeting the Challenge of Specific Brain Pharmacotherapeutics,
Non-Ligand-Based Central Nervous System Targeting, Including Magnetic
Focusing .................................................................................................................147
David F. Moore, Vinith Yathindranath, Torsten Hegmann, Donald Miller,
Marc Pelletier, and Raphael Schiffmann
Chapter 12 Intralesional and Intraparenchymal Convection-Enhanced Delivery of
Nanoparticles ............................................................................................................155
Tatsuhiro Fujii, Daniel Angeles, Li-Chen Hsu, Rahul Jandial, and Mike Y. Chen
Chapter 13 Transport of Nanoparticles across Blood–Brain Barrier .........................................163
Robert T. Wicks, Zev A. Binder, and Alessandro Olivi
Chapter 14 Nanomedicine Treatment Strategies That Exploit Unique Characteristics of
Tumor Vasculature and Microenvironment .............................................................175
Jun Wu, Tatsuhiro Fujii, and Mike Y. Chen
Chapter 15 Focused Ultrasound for Noninvasive Neuromodulation ..........................................187
Martin O. Culjat, Richard E. Fan, Meghedi Babakhanian,
Amit P. Mulgaonkar, Rahul S. Singh, Warren S. Grundfest, and William P. Melega
Chapter 16 Nanosensors .............................................................................................................203
J. Matthew Dubach and Heather A. Clark
Chapter 17 Implantable Infusion Pumps Incorporating Nanotechnology ..................................217
Ellis Meng, Tuan Hoang, and Uttam Sinha
Chapter 18 Nanostructured Surfaces for Intracerebral Neurotransmitter Recording ................231
David A. Price, Artin Petrossians, Pooja M. Talauliker, Francois Pomerleau,
Peter Huettl, Florian Mansfeld, James Weiland, J. Todd Hastings,
and Greg A. Gerhardt
Chapter 19 Therapy for Neuronopathic Lysosomal Storage Diseases ........................................243
Ayaz M. Khawaja, John D. Heiss, and Roscoe O. Brady
Chapter 20 Nanotechnology for Cerebral Aneurysm Treatment ................................................259
Jean Paul Allain, Teodoro Tigno, and Rocco Armonda
© 2010 Taylor & Francis Group, LLC