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The role of technological advances in sodium prescription and adequacy assessment during hemodialysis Citation for published version (APA): Moret, K. E. (2011). The role of technological advances in sodium prescription and adequacy assessment during hemodialysis. [Doctoral Thesis, Maastricht University]. Maastricht University. https://doi.org/10.26481/dis.20110121km Document status and date: Published: 01/01/2011 DOI: 10.26481/dis.20110121km Document Version: Publisher's PDF, also known as Version of record Please check the document version of this publication: • A submitted manuscript is the version of the article upon submission and before peer-review. There can be important differences between the submitted version and the official published version of record. People interested in the research are advised to contact the author for the final version of the publication, or visit the DOI to the publisher's website. • The final author version and the galley proof are versions of the publication after peer review. • The final published version features the final layout of the paper including the volume, issue and page numbers. Link to publication General rights Copyright and moral rights for the publications made accessible in the public portal are retained by the authors and/or other copyright owners and it is a condition of accessing publications that users recognise and abide by the legal requirements associated with these rights. • Users may download and print one copy of any publication from the public portal for the purpose of private study or research. • You may not further distribute the material or use it for any profit-making activity or commercial gain • You may freely distribute the URL identifying the publication in the public portal. If the publication is distributed under the terms of Article 25fa of the Dutch Copyright Act, indicated by the “Taverne” license above, please follow below link for the End User Agreement: www.umlib.nl/taverne-license Take down policy If you believe that this document breaches copyright please contact us at: [email protected] providing details and we will investigate your claim. Download date: 12 Mar. 2023 The role of technological advances in sodium prescription and adequacy assessment during hemodialysis © Marcella van Leeuwen, Maastricht Layout: Tiny Wouters Production: Datawyse | Universitaire Pers Maastricht ISBN: 978-94-6159-029-9 The financial support for the printing of this thesis, received from the following companies, is gratefully acknowledged: Abbott BV, Amgen BV, Baxter BV, Cair Nederland BV, Esaote-Pie Medical BV, Fresenius Medical Care BV, Gambro-Hospal BV, Roche Nederland BV, Shire, Transonic Systems Europe BV. The role of technological advances in sodium prescription and adequacy assessment during hemodialysis PROEFSCHRIFT Ter verkrijging van de graad van doctor aan de universiteit van Maastricht, op gezag van de Rector Magnificus, Prof. mr. G.P.M.F. Mols, volgens het besluit van het College van Decanen, in het openbaar te verdedigen op vrijdag 21 januari 2011 om 16.00 uur door Karin Elisabeth Maria Moret Geboren op 21 april 1968 in Eindhoven U P M UNIVERSITAIRE PERSMAASTRICHT Promotor: Prof. dr. K.M.L. Leunissen Copromotores: Dr. J.P. Kooman Dr. C.H. Beerenhout, Maxima Medisch Centrum, Veldhoven Beoordelingscommissie: Prof. dr. A.P.G. Hoeks (voorzitter) Dr. P.J. Blankestijn, UMC Utrecht Prof. dr. J.P. van Hooff Prof. dr. R.P. Koopmans Dr. P. Kotanko, Renal Research Institute, New York Voor Papa Contents Chapter 1 Introduction 9 Chapter 2 Aim and outline of the thesis 35 Chapter 3 Ionic mass balance and blood volume preservation during a high, 39 standard, and individualized dialysate sodium concentration Chapter 4 Variations in pre‐dialytic plasma conductivity in dialysis patients: 53 effect on ionic mass balance, blood pressure and interdialytic weight gain Chapter 5 The effect of sodium profiling and feedback technologies on 73 plasma conductivity and ionic mass balance: a study in hypotension‐prone dialysis patients Chapter 6 Conductivitypulses needed for Diascan® measurements: Does it 87 cause sodium burden? Chapter 7 Agreement between different parameters of dialysis dose in 93 achieving treatment targets: results from the NECOSAD study. Chapter 8 Ionic dialysance and the assessment of Kt/V: the influence of 109 different estimates of V on method agreement Chapter 9 Summary and discussion 127 Samenvatting en conclusies 143 Dankwoord 161 Curriculum Vitae 167 9 1 Chapter Introduction The role of technological advances in sodium prescription and adequacy assessment during hemodialysis
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