The Role of Complementary and Alternative Medicine in Regenerative Medicine PDF
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Evidence-Based Complementary and Alternative Medicine The Role of Complementary and Alternative Medicine in Regenerative Medicine Guest Editors: Yueh-Sheng Chen, Wei-Chiang Lin, and Cheryl Miller The Role of Complementary and Alternative Medicine in Regenerative Medicine Evidence-Based Complementary and Alternative Medicine The Role of Complementary and Alternative Medicine in Regenerative Medicine Guest Editors: Yueh-Sheng Chen, Wei-Chiang Lin, and Cheryl Miller Copyright©2013HindawiPublishingCorporation.Allrightsreserved. Thisisaspecialissuepublishedin“Evidence-BasedComplementaryandAlternativeMedicine.”Allarticlesareopenaccessarticles distributedundertheCreativeCommonsAttributionLicense,whichpermitsunrestricteduse,distribution,andreproductioninany medium,providedtheoriginalworkisproperlycited. Editorial Board MahmoodA.Abdulla,Malaysia Jen-HweyChiu,Taiwan Ching-LiangHsieh,Taiwan JonAdams,Australia WilliamC.S.Cho,HongKong JingHu,China ZurainiAhmad,Malaysia JaeYoulCho,Korea GanSiewHua,Malaysia UlyssesP.Albuquerque,Brazil S.-H.Cho,RepublicofKorea Sheng-TengHuang,Taiwan GianniAllais,Italy CheeYanChoo,Malaysia BennyT.K.Huat,Singapore TerjeAlraek,Norway RyowonChoue,RepublicofKorea RomanHuber,Germany SoulimanAmrani,Morocco Shuang-EnChuang,Taiwan AngeloAntonioIzzo,Italy AkshayAnand,India Joo-HoChung,RepublicofKorea KongJ.,USA ShrikantAnant,USA EdwinL.Cooper,USA SureshJadhav,India ManuelArroyo-Morales,Spain GregoryD.Cramer,USA KanokwanJarukamjorn,Thailand SyedM.B.Asdaq,SaudiArabia MengCui,China YongJiang,China SeddighehAsgary,Iran RobertoK.N.Cuman,Brazil ZhengL.Jiang,China HyunsuBae,RepublicofKorea VincenzoDeFeo,Italy StefanieJoos,Germany LijunBai,China Roc´ıoDelaPuertaVa´zquez,Spain SirajudeenK.N.S.,Malaysia SandipK.Bandyopadhyay,India MartinDescarreaux,USA Z.Kain,USA SarangBani,India AlexandraDeters,Germany OsamuKanauchi,Japan VassyaBankova,Bulgaria SivaS.K.Durairajan,HongKong DaeGillKang,RepublicofKorea WinfriedBanzer,Germany MohamedEddouks,Morocco WenyiKang,China VernonA.Barnes,USA ThomasEfferth,Germany Shao-HsuanKao,Taiwan SamraBashir,Pakistan TobiasEsch,Germany KrishnaKaphle,Nepal JairoKenuppBastos,Brazil SaeedEsmaeili-Mahani,Iran KenjiKawakita,Japan SujitBasu,USA NianpingFeng,China JongY.Kim,RepublicofKorea DavidBaxter,NewZealand YibinFeng,HongKong Cheorl-HoKim,RepublicofKorea Andre-MichaelBeer,Germany JosueFernandez-Carnero,Spain YounC.Kim,RepublicofKorea AlvinJ.Beitz,USA JulianoFerreira,Brazil YoshiyukiKimura,Japan YongC.Boo,RepublicofKorea FabioFirenzuoli,Italy JoshuaK.Ko,China FrancescaBorrelli,Italy PeterFisher,UK ToshiakiKogure,Japan GloriaBrusotti,Italy W.F.Fong,HongKong NandakumarKrishnadas,India IshfaqA.Bukhari,Pakistan RomainForestier,France YiuWaKwan,HongKong ArndtBu¨ssing,Germany JoelJ.Gagnier,Canada KuangChiLai,Taiwan RainerW.Bussmann,USA Jian-LiGao,China ChingLan,Taiwan RaffaeleCapasso,Italy GabinoGarrido,Chile AlfredLngler,Germany OpherCaspi,Israel MuhammadN.Ghayur,Pakistan LixingLao,HongKong HanChae,Korea AnwarulH.Gilani,Pakistan ClaraBik-SanLau,HongKong Shun-WanChan,HongKong MichaelGoldstein,USA Jang-HernLee,RepublicofKorea Il-MooChang,RepublicofKorea MahabirP.Gupta,Panama TatleangLee,Singapore RajnishChaturvedi,India MitchellHaas,USA MyeongS.Lee,UK ChunTaoChe,USA SveinHaavik,Norway ChristianLehmann,Canada Tzeng-JiChen,Taiwan AbidHamid,India MarcoLeonti,Italy KevinChen,USA N.Hanazaki,Brazil LawrenceLeung,Canada Jian-GuoChen,China KBHarikumar,India KwokNamLeung,HongKong HubiaoChen,HongKong CoryS.Harris,Canada Ping-ChungLeung,HongKong YunfeiChen,China ThierryHennebelle,France ChunGuangLi,Australia Juei-TangCheng,Taiwan Seung-HeonHong,Korea Xiu-MinLi,USA EvanPaulCherniack,USA MarkusHorneber,Germany ShaoLi,China PingLi,China AndreaPieroni,Italy MeiTian,China ManLi,China RichardPietras,USA EvelinTiralongo,Australia MinLi,China WarisQidwai,Pakistan S.C.Tjen-A-Looi,USA YongHongLiao,China XianqinQu,Australia MichaThlfjTomczyk,Poland SabinaLim,Korea CassandraL.Quave,USA YaoTong,HongKong WenChuanLin,China RojaRahimi,Iran K.V.Trinh,Canada Bi-FongLin,Taiwan KhalidRahman,UK KarlWah-KeungTsim,HongKong ChristopherG.Lis,USA CheppailRamachandran,USA VolkanTugcu,Turkey GerhardLitscher,Austria GamalRamadan,Egypt Yew-MinTzeng,Taiwan KeLiu,China KeRen,USA DawnM.Upchurch,USA I-MinLiu,Taiwan ManHeeRhee,RepublicofKorea MarynaVandeVenter,SouthAfrica GaofengLiu,China Mee-RaRhyu,RepublicofKorea SandyvanVuuren,SouthAfrica YijunLiu,USA Jose´LuisR´ıos,Spain AlfredoVannacci,Italy Cun-ZhiLiu,China PaoloRobertidiSarsina,Italy ManiVasudevan,Malaysia GailB.Mahady,USA BasharSaad,PalestinianAuthority CarloVentura,Italy JurajMajtan,Slovakia SumairaSahreen,Pakistan WagnerVilegas,Brazil SubhashC.Mandal,India OmarSaid,Israel PradeepVisen,Canada J.L.Marnewick,SouthAfrica LuisA.Salazar-Olivo,Mexico AristoVojdani,USA VirginiaS.Martino,Argentina Mohd.ZakiSalleh,Malaysia Y.Wang,USA JamesH.McAuley,Australia AndreasSandner-Kiesling,Austria Shu-MingWang,USA KarinMeissner,USA AdairSantos,Brazil Chong-ZhiWang,USA AndreasMichalsen,Germany G.Schmeda-Hirschmann,Chile ChenchenWang,USA DavidMischoulon,USA AndrewScholey,Australia KenjiWatanabe,Japan SyamMohan,Malaysia VeroniqueSeidel,UK J.Wattanathorn,Thailand J.Molnar,Hungary SenthamilR.Selvan,USA WolfgangWeidenhammer,Germany ValrioMonteiro-Neto,Brazil TuhinadriSen,India JennyM.Wilkinson,Australia Hyung-InMoon,RepublicofKorea HongcaiShang,China DarrenWilliams,RepublicofKorea AlbertMoraska,USA RonaldSherman,USA HarukiYamada,Japan MarkMoss,UK KarenJ.Sherman,USA NobuoYamaguchi,Japan YoshiharuMotoo,Japan KuniyoshiShimizu,Japan Yong-QingYang,China FraukeMusial,Germany KanShimpo,Japan JunqingYang,China MinKyunNa,RepublicofKorea Byung-CheulShin,Korea XiufenYang,China RichardL.Nahin,USA YukihiroShoyama,Japan LingYang,China VitalyNapadow,USA ChangGueSon,Korea EunJinYang,RepublicofKorea F.R.F.Nascimento,Brazil RachidSoulimani,France KenYasukawa,Japan S.Nayak,TrinidadAndTobago DidierStien,France MinH.Ye,China IsabellaNeri,Italy Shan-YuSu,Taiwan M.Yoon,RepublicofKorea T.B.Nguelefack,Cameroon MohdRoslanSulaiman,Malaysia JieYu,China MartinOffenbacher,Germany VenilN.Sumantran,India HongQ.Zhang,HongKong Ki-WanOh,RepublicofKorea JohnR.S.Tabuti,Uganda ZunjianZhang,China Y.Ohta,Japan TokuTakahashi,USA Wei-boZhang,China OlumayokunA.Olajide,UK RabihTalhouk,Lebanon Jin-LanZhang,China ThomasOstermann,Germany YupingTang,China BoliZhang,China StaceyA.Page,Canada Wen-FuTang,China RuixinZhang,USA Tai-LongPan,Taiwan LayKekTeh,Malaysia HongZhang,Sweden BhushanPatwardhan,India MayankThakur,India HaiboZhu,China BeritSmestadPaulsen,Norway MenakaC.Thounaojam,India Contents TheRoleofComplementaryandAlternativeMedicineinRegenerativeMedicine,Yueh-ShengChen, Wei-ChiangLin,andCherylMiller Volume2013,ArticleID420458,2pages Long-TermRegenerationandFunctionalRecoveryofa15mmCriticalNerveGapBridgedbyTremella fuciformisPolysaccharide-ImmobilizedPolylactideConduits,Shan-huiHsu,Shan-HoChan, Chih-tsungWeng,Shu-HuiYang,andChing-FenJiang Volume2013,ArticleID959261,12pages PotentialOsteoporosisRecoverybyDeepSeaWaterthroughBoneRegenerationinSAMP8Mice, Hen-YuLiu,Ming-CheLiu,Ming-FuWang,Wei-HongChen,Ching-YuTsai,Kuan-HsienWu, Che-TongLin,Ying-HuaShieh,RongZeng,andWin-PingDeng Volume2013,ArticleID161976,11pages ReconstitutionofKidneySidePopulationCellsafterIschemia-ReperfusionInjurybySelf-Proliferation andBoneMarrow-DerivedCellHoming,HongbaoLiu,WeihuiLiu,ShuibingLiu,QiuhongMeng, NingZhang,HanminWang,RongLi,LiminWang,PengZhang,andShirenSun Volume2013,ArticleID370961,9pages Garlic-DerivedS-AllylmercaptocysteineAmelioratesNonalcoholicFattyLiverDiseaseinaRatModel throughInhibitionofApoptosisandEnhancingAutophagy,JiaXiao,RuiGuo,Man-LungFung, EmilyC.Liong,RaymondChuenChungChang,Yick-PangChing,andGeorgeL.Tipoe Volume2013,ArticleID642920,11pages HepatoprotectiveActivityofMethanolicExtractofBauhiniapurpureaLeavesagainst Paracetamol-InducedHepaticDamageinRats,F.Yahya,S.S.Mamat,M.F.F.Kamarolzaman, A.A.Seyedan,K.F.Jakius,N.D.Mahmood,M.S.Shahril,Z.Suhaili,N.Mohtarrudin, D.Susanti,M.N.Somchit,L.K.Teh,M.Z.Salleh,andZ.A.Zakaria Volume2013,ArticleID636580,10pages Neonaucleareticulata(Havil.)MerrStimulatesSkinRegenerationafterUVBExposureviaROS ScavengingandModulationoftheMAPK/MMPs/CollagenPathway,Hsiu-MeiChiang, Hsin-ChunChen,Hua-HsienChiu,Chien-WenChen,Ssu-MengWang,andKuo-ChingWen Volume2013,ArticleID324864,9pages HepatitisBVirus-EncodedXProteinDownregulatesEGFRExpressionviaInducingMicroRNA-7in HepatocellularCarcinomaCells,Yun-JuChen,Pei-HsuanChien,Wen-ShuChen,Yu-FongChien, Ya-YingHsu,Li-YunWang,Jhen-YuChen,Chih-WenLin,Tzung-ChiHuang,Yung-LuenYu, andWei-ChienHuang Volume2013,ArticleID682380,10pages ReconstructiveEffectsofPercutaneousElectricalStimulationCombinedwithGGTCompositeon LargeBoneDefectinRats,Bo-YinYang,Tzung-ChiHuang,Yueh-ShengChen,andChun-HsuYao Volume2013,ArticleID607201,9pages FerulicAcidEnhancesPeripheralNerveRegenerationacrossLongGaps,Sheng-ChiLee, Chin-ChuanTsai,Chun-HsuYao,Yueh-ShengChen,andMing-ChangWu Volume2013,ArticleID876327,8pages Anti-InflammatoryandNeuroprotectiveEffectsofConstituentsIsolatedfromRhodiolarosea, YeonjuLee,Jae-ChulJung,SoyongJang,JieunKim,ZulfiqarAli,IkhlasA.Khan,andSeikwanOh Volume2013,ArticleID514049,9pages ANewTypeofBiphasicCalciumPhosphateCementasaGentamicinCarrierforOsteomyelitis, Wen-YuSu,Yu-ChunChen,andFeng-HueiLin Volume2013,ArticleID801374,9pages ExperimentalandClinicalPharmacologyofAndrographispaniculataandItsMajorBioactive PhytoconstituentAndrographolide,ThanasekaranJayakumar,Cheng-YingHsieh,Jie-JenLee, andJoen-RongSheu Volume2013,ArticleID846740,16pages ElectroacupunctureandAcupuncturePromotetheRat’sTransectedMedianNerveRegeneration, C.Y.Ho,C.H.Yao,W.C.Chen,W.C.Shen,andD.T.Bau Volume2013,ArticleID514610,7pages HindawiPublishingCorporation Evidence-BasedComplementaryandAlternativeMedicine Volume2013,ArticleID420458,2pages http://dx.doi.org/10.1155/2013/420458 Editorial The Role of Complementary and Alternative Medicine in Regenerative Medicine Yueh-ShengChen,1Wei-ChiangLin,2andCherylMiller3 1SchoolofChineseMedicine,ChinaMedicalUniversity,Taichung40402,Taiwan 2DepartmentofBiomedicalEngineering,FloridaInternationalUniversity,Miami,FL33174,USA 3DepartmentofSurgery,SaintLouisUniversity,St.Louis,MO63103,USA CorrespondenceshouldbeaddressedtoYueh-ShengChen;[email protected] Received1August2013;Accepted1August2013 Copyright©2013Yueh-ShengChenetal. This is an open access article distributed under the Creative Commons Attribution License,whichpermitsunrestricteduse,distribution,andreproductioninanymedium,providedtheoriginalworkisproperly cited. Regenerative medicine is the process of replacing or regen- examinedthecontributionofsidepopulation(SP)cellsfrom eratinganimalcells,tissues,ororganstorestoreorestablish kidneyandbonemarrowtothereconstitutionofkidneySP normal function. This field has the potential to solve the pools after ischemia-reperfusion injury (IRI). They found problemoftheshortageoforgansavailablefordonationand thatfollowingrenalIRI,kidneySPcellswereacutelydepleted oforgantransplantrejection.Recently,applicationofCom- and then progressively restorated to baseline levels by both plementaryandAlternativeMedicine(CAM)asameansto self-proliferationandextrarenalsource,thatis,bonemarrow- acceleratetheprocessofregenerationisanewapproach.The derivedcellhoming.Dr.F.Yahyaetal.showedthatmethanol CAMtherapiesofferanaturalandcost-effectiveintervention extract of Bauhinia purpurea leaves could exert potential tochangethecourseofchronicdiseaseandmayregenerate hepatoprotective activity in rats via its antioxidant activity failingorgansystems. andhighphenoliccontent.T.Jayakumaretal.reviewedthe The paper by Dr. Y.–J. Chen et al. explores how the effects ofandrographolide,a majorbioactivechemical con- Hepatitis B virus-encoded X regulates the expression of stituent in Andrographis paniculata (Burm.f.) Nees, against epidermal growth factor receptor, an important gene for cardiovasculardisease,plateletactivation,infertility,andNF- growthofhepatocytes.Dr.H.–Y.Liuetal.demonstratedthe kBactivation.Dr.H.–M.Chiangetal.showedtheantioxidant regenerative potentials of deep sea water on osteogenesis, activity of a Neonauclea reticulata water extract against showingthatdeepseawatercouldpotentiallybeappliedin ultravioletB(UVB)irradiationinhumanskinfibroblastcell osteoporosistherapy.Dr.S.–H.Hsuetal.preparedperipheral cultures(Hs68)byinhibitingMMP-1,-3,and-9expressions nerve conduits containing the negatively charged Tremella andincreasinglevelsofcollagenactivity.Dr.W.–Y.Suetal. fuciformispolysaccharide(TF)andsuccessfullyusedtheTF- developed a biphasic calcium phosphate cement, consist- immobilized conduits to repair a large (15mm) critical gap ing of 𝛼-tricalcium phosphate (𝛼-TCP) and hydroxyapatite defect in rats. Y. Lee et al. found that L-glutamate-induced (HAP), which is a potential biomaterial for bone repair. C. neurotoxicity could be suppressed by the treatment with Y.Hoetal.showedthatacupunctureandelectroacupuncture constituents of Rhodiola rosea, indicating that the Rhodiola couldhavepositiveeffectsonregenerationofmediannerve rosea may have therapeutic potential for the treatment of in rats. J. Xiao et al. demonstrated that administration of inflammationandneurodegenerativedisease.Dr.B.–Y.Yang garlic-derived antioxidant S-allylmercaptocysteine (SAMC) et al. tried to apply percutaneous electrical stimulation to couldamelioratehepaticinjuryinanonalcoholicfattyliver improveboneremodelingandbonehealinginrats.X-rayand diseaseratmodel.Dr.S.–C.Leeetal.investigatedtheeffectof micro-CTshowedthattheelectricaltreatmentcouldincrease ferulicacid(FA)againstperipheralnerveinjury.Theyfound the amount of newly formed cranial bone. W. Liu et al. that FA appears to promote peripheral nerve regeneration 2 Evidence-BasedComplementaryandAlternativeMedicine across a 15mm critical defect gap in the rat sciatic nerve injurymodel.SuppressionofmacrophagesbyFAatthesiteof peripheralnerveinjurymaycontributetoitsnervegrowth- promotingcapability. By compiling these articles, we hope to stimulate our readersandresearcherstoprovidecontinuingeffortstofully understand the effects of CAM therapies on regenerating tissuesororgans. Yueh-ShengChen Wei-ChiangLin CherylMiller
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