The renal drug handbook: the ultimate prescribing guide for renal practitioners PDF
Preview The renal drug handbook: the ultimate prescribing guide for renal practitioners
The Renal Drug Handbook The ultimate prescribing guide for renal practitioners FOURTH EDITION Edited by Caroline Ashley and Aileen Dunleavy UK Renal Pharmacy Group Foreword by Professor David C Wheeler Professor of Kidney Medicine University College London President, Renal Association Boca Raton London New York CRC Press is an imprint of the Taylor & Francis Group, an informa business CRC Press Taylor & Francis Group 6000 Broken Sound Parkway NW, Suite 300 Boca Raton, FL 33487-2742 © 2014 Caroline Ashley and Aileen Dunleavy CRC Press is an imprint of Taylor & Francis Group, an Informa business No claim to original U.S. Government works Printed on acid-free paper Version Date: 20140214 International Standard Book Number-13: 978-1-9093-6894-1 (Hardback) This book contains information obtained from authentic and highly regarded sources. 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Visit the Taylor & Francis Web site at http://www.taylorandfrancis.com and the CRC Press Web site at http://www.crcpress.com Contents Foreword to the fourth edition xii Preface to the fourth edition xiii About the editors xvii List of abbreviations xviii Abacavir 1 Amifostine 41 Abatacept 2 Amikacin 42 Abciximab 3 Amiloride hydrochloride 44 Abiraterone acetate 4 Aminophylline 45 Acamprosate calcium 5 Amiodarone hydrochloride 47 Acarbose 6 Amisulpride 49 Acebutolol 7 Amitriptyline hydrochloride 51 Aceclofenac 9 Amlodipine 53 Acenocoumarol (nicoumalone) 10 Amoxicillin 54 Acetazolamide 12 Amphotericin IV – Abelcet (lipid complex) 55 Acetylcysteine 13 Amphotericin IV – AmBisome (liposomal) 57 Aciclovir IV 14 Amphotericin IV – Fungizone 59 Aciclovir oral 16 Ampicillin 61 Acipimox 17 Amsacrine 62 Acitretin 18 Anagrelide 63 Acrivastine 19 Anakinra 64 Adalimumab 20 Anastrozole 65 Adefovir dipivoxil 21 Anidulafungin 66 Adenosine 22 Apixaban 67 Adrenaline (epinephrine) 23 Apomorphine hydrochloride 68 Albendazole (unlicensed product) 24 Aprepitant 69 Aldesleukin 25 Argatroban 70 Alemtuzumab (MabCampath) (unlicensed) 26 Aripiprazole 72 Alendronic acid 27 Arsenic trioxide 74 Alfacalcidol 28 Artemether with lumefantrine 76 Alfentanil 29 Ascorbic acid 77 Alfuzosin hydrochloride 31 Asenapine 78 Alimemazine tartrate (trimeprazine) 32 Aspirin 79 Aliskiren fumarate 33 Atazanavir 81 Allopurinol 34 Atenolol 83 Almotriptan 35 ATG (Rabbit) (Thymoglobuline) 85 Alteplase (rt-PA) (recombinant human Atorvastatin 87 tissue-type plasminogen activator) 36 Atovaquone 89 Aluminium hydroxide 38 Atracurium besilate 90 Amantadine hydrochloride 39 Axitinib 91 Ambrisentan 40 Azacitidine 92 iv CONTENTS Azathioprine 93 Capecitabine 146 Azilsartan medoxomil 95 Capreomycin 147 Azithromycin 96 Captopril 148 Aztreonam 98 Carbamazepine 150 Carbimazole 152 Baclofen 99 Carboplatin 153 Balsalazide sodium 100 Carmustine 154 Basiliximab 101 Carvedilol 155 Belatacept 102 Caspofungin 157 Belimumab 103 Cefaclor 158 Bendamustine hydrochloride 104 Cefadroxil 159 Bendrofl umethiazide 105 Cefalexin 160 Benzbromarone (unlicensed product) 107 Cefi xime 161 Benzylpenicillin 108 Cefotaxime 162 Betahistine dihydrochloride 109 Cefpodoxime 163 Betamethasone 110 Cefradine 164 Betaxolol hydrochloride 111 Ceftaroline 165 Bevacizumab 112 Ceftazidime 166 Bexarotene 113 Ceftriaxone 167 Bezafi brate 114 Cefuroxime (oral) 168 Bicalutamide 115 Cefuroxime (parenteral) 169 Bilastine 116 Celecoxib 170 Bisacodyl 117 Celiprolol hydrochloride 172 Bisoprolol fumarate 118 Certolizumab pegol 173 Bivalirudin 119 Cetirizine hydrochloride 174 Bleomycin 120 Cetuximab 175 Boceprevir 122 Chloral hydrate 176 Bortezomib 124 Chlorambucil 177 Bosentan 125 Chloramphenicol 178 Brentuximab vedotin 127 Chlordiazepoxide hydrochloride 179 Bromocriptine 128 Chloroquine 180 Budesonide 129 Chlorphenamine maleate Bumetanide 130 (chlorpheniramine) 182 Buprenorphine 132 Chlorpromazine hydrochloride 183 Bupropion hydrochloride Chlortalidone (chlorthalidone) 185 (amfebutamone HCL) 133 Ciclosporin 187 Buserelin 134 Cidofovir 189 Buspirone hydrochloride 135 Cilazapril 191 Busulfan 136 Cilostazol 192 Cimetidine 194 Cabazitaxel 137 Cinacalcet 196 Cabergoline 138 Cinnarizine 197 Calcitonin (salmon)/salcatonin 139 Ciprofi brate 198 Calcitriol 140 Ciprofl oxacin 199 Calcium acetate 141 Cisplatin 201 Calcium carbonate 142 Citalopram 203 Calcium gluconate 143 Cladribine 205 Calcium resonium 144 Clarithromycin 206 Candesartan cilexetil 145 Clemastine 208 CONTENTS v Clindamycin 209 Decitabine 268 Clobazam 210 Deferasirox 269 Clofazimine 211 Deferiprone 270 Clomethiazole (chlormethiazole) 212 Defl azacort 271 Clomipramine hydrochloride 213 Degarelix 272 Clonazepam 215 Demeclocycline hydrochloride 273 Clonidine hydrochloride 216 Denosumab 274 Clopidogrel 217 Desferrioxamine mesilate 275 Clozapine 218 Desirudin (unlicensed product) 277 Co-amoxiclav (amoxicillin/clavulanic acid) 220 Desloratadine 278 Co-beneldopa (Madopar) 222 Desmopressin (DDAVP) 279 Co-careldopa (Sinemet) 223 Dexamethasone 280 Co-codamol (paracetamol and codeine Dexibuprofen 282 phosphate) 224 Dexketoprofen 284 Codeine phosphate 226 Diamorphine hydrochloride 286 Co-dydramol (paracetamol and Diazepam 287 dihydrocodeine) 227 Diazoxide 289 Colchicine 228 Diclofenac sodium 290 Colesevelam hydrochloride 230 Didanosine 292 Colestipol hydrochloride 231 Digoxin 293 Colestyramine (cholestyramine) 232 Dihydrocodeine tartrate 295 Colistimethate sodium (Colistin) 233 Diltiazem hydrochloride 296 Co-trimoxazole (trimethoprim + Dipyridamole 298 sulfamethoxazole) 235 Disodium etidronate 299 Crisantaspase 237 Disodium pamidronate 300 Crizotinib 238 Disopyramide 301 Cyclizine 240 Disulfi ram 303 Cyclopenthiazide 241 Dobutamine 304 Cyclophosphamide 242 Docetaxel 305 Cycloserine 244 Domperidone 306 Cyproheptadine hydrochloride 245 Donepezil hydrochloride 307 Cyproterone acetate 246 Dopamine hydrochloride 308 Cytarabine 247 Dopexamine hydrochloride 309 Cytomegalovirus (CMV) human Doripenem 310 immunoglobulin (unlicensed product) 249 Dornase alfa 311 Dosulepin hydrochloride (dothiepin) 312 Dabigatran etexilate 250 Doxapram hydrochloride 314 Dacarbazine 252 Doxazosin 315 Dactinomycin 253 Doxepin 316 Dalteparin sodium (LMWH) 254 Doxorubicin hydrochloride 318 Danaparoid sodium 256 Doxycycline 320 Dapaglifl ozin 258 Dronedarone 321 Dapsone 259 Droperidol 323 Daptomycin 260 Duloxetine 325 Darbepoetin alfa 262 Dutasteride 326 Darifenacin 264 Darunavir 265 Eculizumab 327 Dasatinib 266 Efavirenz 328 Daunorubicin 267 Eletriptan 330 vi CONTENTS Eltrombopag 332 Fesoterodine fumarate 398 Emtricitabine 334 Fexofenadine hydrochloride 399 Enalapril maleate 335 Fidaxomicin 400 Enfuvirtide 337 Filgrastim 401 Enoxaparin sodium (LMWH) 338 Finasteride 402 Entacapone 340 Fingolimod 403 Entecavir 341 Flecainide acetate 404 Epirubicin hydrochloride 342 Flucloxacillin 406 Eplerenone 344 Fluconazole 407 Epoetin alfa (Eprex) 346 Flucytosine 409 Epoetin beta (Neorecormon) 348 Fludarabine phosphate 410 Epoprostenol (prostacyclin) 350 Fludrocortisone acetate 411 Eprosartan 351 Flumazenil 412 Eptifi batide 352 Fluorouracil 413 Eribulin 353 Fluoxetine 414 Erlotinib 354 Flupentixol 416 Ertapenem 356 Flurbiprofen 417 Erythromycin 357 Flutamide 419 Escitalopram 359 Fluvastatin 420 Eslicarbazepine acetate 361 Fluvoxamine maleate 421 Esmolol hydrochloride 362 Folic acid 423 Esomeprazole 364 Folinic acid (calcium folinate) 424 Estramustine phosphate 366 Fondaparinux sodium 425 Etamsylate 367 Formoterol fumarate (eformoterol) 427 Etanercept 368 Fosamprenavir 428 Ethambutol hydrochloride 369 Fosaprepitant 430 Ethosuximide 370 Foscarnet sodium 431 Etodolac 371 Fosfomycin (unlicensed) 433 Etomidate 373 Fosinopril sodium 434 Etoposide 374 Fosphenytoin sodium 435 Etoricoxib 376 Frovatriptan 437 Etravirine 378 Fulvestrant 438 Everolimus 379 Furosemide (frusemide) 439 Exemestane 380 Exenatide 381 Gabapentin 441 Ezetimibe 382 Galantamine 442 Ganciclovir 443 Famciclovir 383 Gefi tinib 445 Famotidine 384 Gemcitabine 446 Febuxostat 385 Gemfi brozil 448 Felodipine 387 Gentamicin 450 Fenofi brate 388 Glatiramer acetate 451 Fenoprofen 389 Glibenclamide 452 Fentanyl 391 Gliclazide 453 Ferric carboxymaltose 393 Glimepiride 454 Ferrous fumarate 394 Glipizide 455 Ferrous gluconate 395 Glyceryl trinitrate 456 Ferrous sulphate 396 Goserelin 457 Ferumoxytol 397 Granisetron 458 CONTENTS vii Griseofulvin 459 Ketamine 523 Guanethidine monosulphate 460 Ketoconazole 525 Ketoprofen 527 Haloperidol 461 Ketorolac trometamol 529 Heparin 463 Ketotifen 531 Hydralazine hydrochloride 464 Klean-Prep 532 Hydrocortisone acetate 465 Hydrocortisone sodium succinate 466 Labetalol hydrochloride 533 Hydromorphone hydrochloride 468 Lacidipine 535 Hydroxycarbamide (hydroxyurea) 469 Lacosamide 536 Hydroxychloroquine sulphate 470 Lactulose 537 Hydroxyzine hydrochloride 472 Lamivudine 538 Hyoscine butylbromide 473 Lamotrigine 539 Hyoscine hydrobromide 474 Lanreotide 541 Lansoprazole 542 Ibandronic acid 475 Lanthanum carbonate 543 Ibuprofen 477 Lapatinib 544 Idarubicin hydrochloride 479 Lefl unomide 545 Ifosfamide 481 Lenalidomide 546 Iloprost 483 Lenograstim 547 Imatinib 484 Lercanidipine hydrochloride 548 Imidapril hydrochloride 486 Letrozole 549 Imipramine hydrochloride 487 Leuprorelin acetate 550 Indapamide 489 Levamisole (unlicensed product) 551 Indinavir 491 Levetiracetam 552 Indometacin 493 Levocetirizine hydrochloride 553 Indoramin 495 Levofl oxacin 554 Infl iximab 496 Levomepromazine (methotrimeprazine) 555 Inositol nicotinate 497 Levothyroxine sodium (thyroxine) 557 Insulin – soluble (Actrapid or Humulin S) 498 Lidocaine hydrochloride (Lignocaine) 558 Interferon alfa-2a (Roferon A) 499 Linagliptin 560 Interferon alfa-2b 501 Linezolid 561 Interferon beta 503 Liothyronine sodium (triiodothyronine) 563 Interferon gamma-1b (Immukin) 504 Liraglutide 564 Ipilimumab 505 Lisinopril 565 Ipratropium bromide 506 Lithium carbonate 566 Irbesartan 507 Lofepramine 568 Irinotecan hydrochloride 508 Lomitapide 570 Iron dextran 5% solution 510 Lomustine 571 Iron isomaltoside 1000 512 Loperamide hydrochloride 572 Iron sucrose 513 Lopinavir 573 Isoniazid 514 Loratadine 575 Isosorbide dinitrate 515 Lorazepam 576 Isosorbide mononitrate 516 Lormetazepam 577 Isotretinoin 517 Losartan potassium 578 Ispaghula husk 518 Lymecycline 579 Isradipine 519 Itraconazole 520 Maraviroc 580 Ivabradine hydrochloride 522 Mebendazole 581 viii CONTENTS Medroxyprogesterone acetate 582 Moxifl oxacin 642 Mefenamic acid 584 Moxisylyte (thymoxamine) 643 Mefl oquine 586 Moxonidine 644 Megestrol acetate 587 Muromonab CD3 (OKT3) (unlicensed) 645 Melatonin 588 Mycophenolate 646 Meloxicam 589 Melphalan 591 Nabumetone 648 Memantine 593 Nadolol 650 Mepacrine hydrochloride (unlicensed Naftidrofuryl oxalate 652 product) 594 Nalidixic acid 653 Meptazinol 595 Nalmefene hydrochloride dihydrate 654 Mercaptopurine 596 Naloxone hydrochloride 655 Meropenem 598 Naltrexone hydrochloride 656 Mesalazine 599 Naproxen 657 Mesna 600 Naratriptan 659 Metformin hydrochloride 601 Natalizumab 660 Methadone hydrochloride 602 Nateglinide 661 Methenamine hippurate 604 Nebivolol 662 Methotrexate 605 Nefopam hydrochloride 664 Methyldopa 607 Nelarabine 665 Methylprednisolone 608 Neomycin sulphate 666 Metoclopramide hydrochloride 609 Neostigmine 667 Metolazone (unlicensed) 610 Nevirapine 668 Metoprolol tartrate 612 Nicardipine hydrochloride 670 Metronidazole 614 Nicorandil 671 Mexiletine hydrochloride (unlicensed) 615 Nicotinic acid (unlicensed) 672 Micafungin 617 Nifedipine 673 Miconazole 618 Nilotinib 675 Midazolam 619 Nimodipine 676 Midodrine hydrochloride (unlicensed) 621 Nitrazepam 678 Mifamurtide 622 Nitrofurantoin 679 Minocycline 623 Nizatidine 680 Minoxidil 624 Noradrenaline acid tartrate Mirabegron 625 (norepinephrine bitartrate) 681 Mircera 626 Norethisterone 682 Mirtazapine 627 Norfl oxacin 683 Misoprostol 628 Normal human immunoglobulin 684 Mitomycin 629 Nortriptyline 686 Mitotane 630 Nystatin 688 Mitoxantrone 631 Mivacurium 632 Octreotide 689 Mizolastine 634 Oestrogen, conjugated (unlicensed Moclobemide 635 product) 690 Modafi nil 636 Ofatumumab 691 Moexipril hydrochloride 637 Ofl oxacin 692 Montelukast 638 Olanzapine 693 Morphine 639 Olmesartan medoxomil 694 Movicol (active ingredient is the Olsalazine sodium 695 osmotic laxative polyethylene glycol) 641 Omalizumab 696 CONTENTS ix Omeprazole 697 Piperazine 754 Ondansetron 698 Piracetam 755 Orlistat 699 Piroxicam 756 Orphenadrine hydrochloride 700 Pivmecillinam hydrochloride 758 Oseltamivir 701 Pizotifen 759 Oxaliplatin 703 Plerixafor 760 Oxazepam 705 Posaconazole 761 Oxcarbazepine 706 Potassium chloride 763 Oxprenolol hydrochloride 707 Pramipexole 764 Oxybutynin hydrochloride 709 Prasugrel 765 Oxycodone hydrochloride 710 Pravastatin sodium 766 Oxytetracycline 711 Praziquantel (unlicensed product) 767 Prazosin 768 Paclitaxel 712 Prednisolone 769 Paliperidone 713 Pregabalin 770 Palonosetron 714 Primaquine phosphate 771 Pancreatin 715 Primaxin (imipenem/cilastatin) 772 Pancuronium bromide 716 Primidone 774 Panitumumab 717 Procainamide hydrochloride Pantoprazole 718 (unlicensed) 776 Papaveretum 719 Procarbazine 778 Paracetamol 720 Prochlorperazine 779 Parathyroid hormone 721 Procyclidine hydrochloride 781 Parecoxib 722 Proguanil hydrochloride 782 Paricalcitol 724 Promazine hydrochloride 783 Paroxetine 725 Promethazine hydrochloride 784 Pazopanib 727 Propafenone hydrochloride 785 Pegfi lgrastim 728 Propiverine hydrochloride 787 Peginterferon alfa 729 Propofol 788 Pemetrexed 730 Propranolol hydrochloride 789 Penicillamine 731 Propylthiouracil 791 Pentamidine isetionate 732 Protamine sulphate 792 Pentostatin 734 Pseudoephedrine hydrochloride 793 Pentoxifylline (oxpentifylline) 735 Pyrazinamide (unlicensed product) 794 Perampanel 736 Pyridostigmine bromide 795 Perindopril 737 Pyridoxine hydrochloride 796 Pethidine hydrochloride 739 Pyrimethamine 797 Phenelzine 740 Phenindione 741 Quetiapine 798 Phenobarbital (phenobarbitone) 742 Quinagolide 800 Phenoxybenzamine hydrochloride 744 Quinapril 801 Phenoxymethylpenicillin (penicillin V) 745 Quinine 802 Phentolamine mesilate 746 Phenytoin 747 Rabeprazole sodium 804 Phosphate supplements 749 Racecadotril 805 Phytomenadione (vitamin K) 750 Raloxifene hydrochloride 806 Pimozide 751 Raltegravir 807 Pindolol 752 Raltitrexed 808 Pioglitazone 753 Ramipril 809
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