The Plastic Surgery Research Council 59th Annual Meeting Abstract

236 Pages·2014·2.56 MB·English

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Plastic and
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Journal of the American Society of Plastic Surgeons
Official Organ of the American Association of Plastic Surgeons
Official Organ of the American Society of Maxillofacial Surgeons
Official Organ of the Plastic Surgery Research Council
The Plastic Surgery
Research Council
59th Annual Meeting
Abstract Supplement
EDITORIAL BOARD
Plastic and Reconstructive Surgery
EDITOR-IN-CHIEF ASSOCIATE EDITORS SECTION EDITORS
Rod J. Rohrich, M.D. William Peter Adams, Jr ., Maurice Nahabedian
Department of Plastic Surgery
Dallas, Texas Washington, D.C. BREAST
University of Texas
Southwestern Medical Center Al Aly, Orange, Calif.
5959 Harry Hines Blvd., POB1 David A. Hidalgo
Suite 300 Charles E. Butler, Houston, Texas COSMETIC
New York, N.Y.
Dallas, Texas 75390-8820
Grant W. Carlson, Atlanta, Ga.
[email protected]
David W. Chang, Chicago, Ill. Paul S. Cederna
CO-EDITOR
Ann Arbor, Mich. EXPERIMENTAL
James M. Stuzin, M.D. Peter G. Cordeiro, New York, N.Y.
3225 Aviation Avenue, Suite 100
Joseph J. Disa, New York, N.Y.
Coconut Grove, Fla. 33133-4753 Matthew J. Concannon
HAND/
REVIEW EDITOR Gregory A. Dumanian, Chicago, Ill. Columbia, Mo. PERIPHERAL NERVE
Ronald P. Gruber, M.D. Steven Fagien, Boca Raton, Fla.
3318 Elm Street Scott P. Bartlett
(Oculoplastic Surgeon) PEDIATRIC/
Oakland, Calif. 94609-3012 Philadelphia, Pa. CRANIOFACIAL
Jeffrey A. Fearon, Dallas, Texas
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EDITOR Robert D. Galiano, Chicago, Ill. Dennis P. Orgill
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Elisabeth J. Hall-Findlay,
2401 S. 31st Street
Donald H. Lalonde
Temple, Texas 76508-0001 Banff, Alberta, Canada
Saint John, New Brunswick, CME/MOC
EDITOR EMERITUS Dennis C. Hammond, Grand Rapids, Mich. Canada
Robert M. Goldwyn, M.D.†
Larry H. Hollier, Jr., Houston, Texas
Brookline, Mass. Kevin C. Chung
OUTCOMES
Steven J. Kronowitz, Houston, Texas Ann Arbor, Mich.
EDITORIAL STAFF
Managing Editor Val S. Lambros, Newport Beach, Calif.
Aaron Weinstein
L. Scott Levin, Philadelphia, Pa.
[email protected]
Joseph E. Losee, Pittsburgh, Pa.
Staff Editor
Edward Tynan Edward A. Luce, Memphis, Tenn.
[email protected]
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Coordinator–Graphic Design
Alan Matarasso, New York, N.Y.
Angela Burch
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I. Donnell Moore
[email protected] J. Peter Rubin, Pittsburgh, Pa. Publisher: Elizabeth Durzy
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Douglas M. Sammer, Dallas, Texas Production Editor: Jeda Taylor
Supplements
Dustin Lang David H. Song, Chicago, Ill. Account Manager: Laura Meyd
[email protected] Dean Toriumi, Chicago, Ill. Advertising Representative:
Editorial Assistant
(Facial Plastic Surgeon) Brian Parker
Neshia Clark
[email protected] Steven G. Wallach, New York, N.Y.
CONSULTING EDITORS ASPS PUBLICATIONS
Raymond V . Janevicius, Elmhurst, Ill. DIRECTOR
CPT-ICD-9 Coding Editor Mike Stokes, Arlington Heights, Ill.
David B. Sarwer, Philadelphia, Pa.
†Deceased
EDITORIAL BOARD
(cOnT.)
INTERNATIONAL ASSOCIATE EDITORS
Plastic and Reconstructive Surgery
Phillip Blondeel (Gent, Belgium) Wei Wang (Shanghai, China)
Osvaldo Saldanha (Santos, Brazil) Lars Steinstraesser (Oldenburg, Germany)
Ricardo Baroudi (São Paulo, Brazil) Isao Koshima (Tokyo, Japan)
Dov C. Goldenberg (São Paulo, Brazil) Fernando Molina (Mexico City, Mexico)
Yilin Cao (Beijing, China) Fu-Chan Wei (Taipei, Taiwan)
Jingheng Gao (Shenyang, China) Nazim Cerkes (Istanbul, Turkey)
PARTNER SOCIETY
ASSOCIATE EDITORS
Rod Cooter Riccardo Mazzola
Australian Society of Plastic Surgeons Società Italiana di Chirugia Plastica Ricostruttiva ed Estetica
Mustapha Hamdi David Mendes
Royal Belgian Society for Plastic Surgery, Reconstructive Israel Society of Plastic & Aesthetic Surgery
and Aesthetic Surgery
Mick Kreulen
Claudio de Castro Nederlandse Vereniging voor Plastische Chirurgie
Sociedade Brasileira de Cirurgia Plástica
Swee Tan
New Zealand Association of Plastic Surgeons
Hiroshi Nishikawa
British Association of Plastic, Reconstructive and Aesthetic Vincent Yeow
Surgeons Singapore Association of Plastic Surgeons
Katia Bustamante Chris Snijman
Société Française de Chirurgie Plastique Reconstructrice et Association of Plastic and Reconstructive Surgeons of
Esthétique Southern Africa
Sean M. Carroll Chul Park
Irish Association of Plastic Surgeons Korean Society of Plastic and Reconstructive Surgeons
Lun-Jou Lo
Taiwan Society of Plastic Surgery
The Plastic Surgery Research Council
59th Annual Meeting
Hosted by Mount Sinai Medical Center
New York, New York
March 7–9, 2014
No Photography or videotaping is allowed during the scientific sessions
without prior approval by the Executive Committee.
www.PRSJournal.com
Plastic and Reconstructive Surgery • March 2014 Supplement
TABLE OF CONTENTS
Officers and Executive Committee . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 3
Welcome From The Chairman . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 4
Letter From The Editor-In-Chief . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 5
Historical Perspectives From The Plastic Surgery Research Council . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 6
Scientific Sessions
Session 1 - Best Paper Plenary Session . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 9
Session 2 - Best Paper Plenary Session . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 19
Session 3A - Assorted . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 29
Session 3B - Assorted . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 35
Session 3C - Wound Healing . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 41
Session 4 - Best EPSRC Papers . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 47
Session 5A - Clinical Outcomes . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 51
Session 5B - Craniofacial/Bone . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 61
Session 5C - Nerve . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 69
Session 6A - Developmental Biology . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 79
Session 6B - Craniofacial/Bone . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 89
Session 6C - Tissue Engineering . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 99
Session 7A - Outcomes . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 109
Session 7B - CTA . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 115
Session 7C - Microsurgery . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 123
Session 8A - Outcomes . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 129
Session 8B - Fat Stem Cells . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 141
Session 8C - Wound Healing . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 153
Session 9A - Ischemia, Reperfusion & Tumor Biology . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 165
Session 9B - Assorted . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 171
Session 9C - Tissue Engineering . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 177
Poster Displays . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 185
Author Index . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 227
Membership Information . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 231
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Volume 133, Number 3 (Supplement) • PSRC Abstract Supplement
59TH ANNuAL MEETiNg OF ThE
PLASTiC SuRgERy RESEARCh COuNCiL
OFFiCERS ANd ExECuTivE COMMiTTEE
Peter J. Taub, MD, FACS, FAAP
Chairman
Howard Levinson, MD
Secretary/Treasurer
David Mathes, MD
Scientific Program Chair
Timothy W. King, MD, PhD
Parliamentarian
William M. Kuzon, Jr., MD, PhD
Historian
James P. Bradley, MD
Past Chairman (2013)
Paul S. Cederna, MD
Trustee/Past Chairman (2012)
Bradon J. Wilhelmi, MD
Trustee/Past Chairman (2011)
Steven R. Buchman, MD
Endowment Chair
Kotaro Yoshimura, MD
Asian Liaison
Lars-Uwe Lahoda, MD, PhD
European Liaison
www.PRSJournal.com 3
Plastic and Reconstructive Surgery • March 2014 Supplement
From the Office of the Chairman
I am thrilled and honored to be hosting the 59th Annual Meeting of the Plastic Surgery Research Council in
my hometown of New York City. New York is described as the “Best City in the World.” It is an easy destination
to get to from most anywhere and has almost everything to offer. While the PSRC has been held here previously,
it has not been in New York since 1995 and this will mark the first time that Mount Sinai Medical Center will
serve as the host institution. I first presented at the PSRC in Galveston, Texas in 1997 as a general surgery
resident and have been an active member since. I believe the PSRC is the most important society of our specialty.
The work performed by our member surgeons is at the forefront of healthcare as a whole. Our members are the
brightest and most creative we have to offer and to that end, I have incredible respect. This year’s meeting will
undoubtedly be exciting and provocative. I am fortunate to be able to plan the meeting with Dr. David Mathes
who brings tremendous energy to our society. Unlike prior years, the entire program will be held at the brand
new Conrad Hotel in Battery Park City, which overlooks the Hudson River, New York harbor, and the Statue of
Liberty. Following the first day of presentations, there will be a Welcome Reception with attendees and exhibitors.
Since the meeting coincides with the annual rite of “March Madness,” we have reserved the basketball court at
Stuyvesant High School for pick-up games after the reception. We may even hold the first lab tournament to be
continued in the following years. Saturday night’s Member’s Dinner will be held at the nearby Tribeca Grill, which
is co-owned by Robert De Niro, and serves a delightful New American menu. The remainder of the night was left
free to explore the “City that Never Sleeps.”
I welcome you to New York and look forward to hosting everyone this spring. Bring sneakers!
Peter J. Taub, MD, FACS, FAAP
2014 PSRC Chair
Mount Sinai Medical Center, New York, NY
The Plastic Surgery Research Council
500 Cummings Center, Suite 4550 – Beverly, Massachusetts – USA
t / 1-978-927-8330 f / 1-978-524-0498 e / [email protected] w / www.ps-rc.org
PSRC Abstract SupplementThe Plastic
Surgery Research Council
4
PSRC Abstract Supplement
Volume 133, Number 3 (Supplement) • PSRC Abstract Supplement
Letter from the Editor-in-Chief
The Plastic Surgery Research Council
59th Annual Meeting Abstract Supplement
Rod J. Rohrich, M.d.
In this edition of the official meeting abstracts of the Plastic Surgery Research Council (PSRC) you will be able to see
the future of our field. This document represents the eighth consecutive time that these abstracts are published as a supplement
to Plastic and Reconstructive Surgery. As Editor-in-Chief, I could not be more proud to have this perennially impressive
document published in the White Journal. If the Journal represents culmination of science in our field, abstract supplements
such as this one represent the birth of those scientific ideas; the abstracts presented for the 59th annual meeting of the PSRC are
the raw ideas for research that will fuel clinical change and new discoveries in the years to come.
Strong ties between the Journal and American Society of Plastic Surgeons (ASPS) have existed for decades; as of this
publication, the Journal has been an Official Organ of the PSRC for just over 8 years. We are grateful for the continuing support
of the Council’s current leaders, especially Chair Peter Taub, Chair-elect David Mathes, Timothy William Kuzon, Howard
Levinson, Steven Buchman and the Council’s international liaisons, Kotaro Yoshimura and Lars-Uwe Lahoda. Their efforts
have lead this organization to some remarkable new discoveries that will be effecting Plastic Surgery in the years to come. In
addition, we recognize the past PSRC leadership of Paul Cederna and Bradon Wilhelmi; the work of these impressive leaders
work continues not only as PSRC Trustees but in myriad other areas of plastic surgery research and clinical application. We
also recognize the work of James Bradley, Development Chair of the PSRC, whose efforts for the future of the organization are
already manifesting in the present. We greatly appreciate the leadership of the ASPS/PSEF, especially ASPS President Robert
X. Murphy, Jr., PSEF President Kevin Chung, ASPS Executive Director Michael Costelloe, ASPS Vice President of Research
and Development Keith Hume, and ASPS Director of Publications Mike Stokes.
The Journal appreciates the ongoing financial support of the ASPS and PSEF to make the PSRC abstract supplement
possible. As with every journal endeavor, we could not have published this special supplement without the efforts, energy and
creativity of our publisher, Lippincott Williams & Wilkins, represented by Elizabeth Durzy. PSRC Executive Director Sara Neece
and her dedicated staff, notably Jillian West (meeting manager) and Amy Nolfi (meeting coordinator), coordinated the receipt and
review of the abstracts, supplied expertly prepared documents, and greatly facilitated the overall production of the supplement.
As with all supplements to Plastic and Reconstructive Surgery, all subscribers have access to all of the PSRC annual
meeting abstracts. As an additional feature, I’m proud to announce that this supplement will be made available free online
at PRSJournal.com for at least three months following publication; any interested party with internet access will have the
ability to read this supplement. This is important because this affords us all a glimpse into what will be hitting the mainstream
clinical plastic surgery advances in one to two years. By sharing this supplement free online, the PSRC is democratizing this
information, giving all in our a field a chance to learn about this research.
The PSRC Meeting Abstract supplement to the Journal will share all the benefits of other PRS supplements, namely:
• Peer review of all content. Abstracts have been reviewed by the PSRC, and only those accepted after undergoing review
are published here.
• Full indexing in such abstracting services as Index Medicus, Abridged Index Medicus, Current Contents/Clinical
Medicine, Life Sciences, Science Citation Index, Research Alert, ISI/Bio Med, EMBASE/Excerpta Medica, and
BIOSIS;
• Broad global readership through both print and web subscriptions and online databases such as OVID. Through the
OVID database, the Journal and its supplements have a potential readership of over 13 million end-users worldwide.
Additionally, the contents of this supplement will be available through the PSRC website (www.psrc.org) as well as
through the Journal’s website (www.PRSJournal.com).
Scientific abstracts can be seen as the essence of scientific studies; the major efforts of study design, data collection, and
interpretation of results have already been performed and are published in these abstracts. We encourage the authors of these
abstracts to submit completed manuscripts based upon their abstracts. We look forward to these authors writing full studies
based on their findings and submitting them to Plastic and Reconstructive Surgery or Plastic and Reconstructive Surgery-
Global Open (PRS GO) through our online system, PRS and PRS GO’s Enkwell (www.editorialmanager.com/prs).
I hope you find the Abstracts of the 59th Annual Meeting of the Plastic Surgery Research Council as fascinating,
challenging and inspiring as I do.
Rod J. Rohrich, M.D.
Editor-in-Chief
University of Texas Southwestern Medical Center
5959 Harry Hines Blvd
Dallas, TX 75390–8820
[email protected]
www.PRSJournal.com 5
PSRC Abstract Supplement
Plastic and Reconstructive Surgery • March 2014 Supplement
Historical Perspective:
The Plastic Surgery Research Council
The following is compiled in part from
Peter Randall’s Thirty-Five Year History of the
Plastic Surgery Research Council
Thomas S. davis, Md
Historian Emeritus
In the early 1950’s there was a “feeling” among “younger” plastic surgeons (those recently boarded or not yet
boarded) of a need for an arena to discuss research in plastic surgery, including works in progress. The major plastic
surgery organizations were perceived as forums for politics and jousting fields for the political giants of the day. The
American College of Surgeons initiated the Surgical Forum in 1949, and later the plastic surgeon section in 1953
under the direction of Dr. Joe Murray. Still, the impression among the younger plastic surgeons was that research
was “taking a back seat” in the mainstream plastic surgery organizations.
An informal meeting was held in San Diego, California in 1954. The “young bucks” enlisted the advice of
trusted and more senior advisors. Drs. Lewis T. Byars (St. Louis), Brad Cannon (Boston), and Truman G. Blocker
(Galveston) listened and lent encouragement. Their recommendations were to hold these meetings in a university
setting and to include the local university talent in discussions in the field of research. Caution was also given
regarding the possible considerable opposition to the formation of such a group. It was agreed that they would meet
the following year. Sixteen individuals were picked to be invited to an “Organizational Meeting” held in Baltimore
in the fall of 1955. The word “picked” implies selecting a few from the many, whereas actually this was more a
search for the “any” from the “few.”
At the time of the founding meeting of the Plastic Surgery Research Council in 1955 at Johns Hopkins, called
by Drs. Milton Edgerton and Robin Anderson, Dr. Richard Stark submitted the drawing of Baronio’s Sheep (1804)
with auto and allografts in situ as a possible logo for the council.
Searching for a form other than the logo cliche of the circle, the design was made into a rectangle with
rounded corners. It was accepted and has been the logo of the council since that time.
Fig. 1. PSRc BAROnIO SHEEP LOGO
Following this first official meeting, Dr. Robin Anderson was asked to compose a Constitution and a set of
By-Laws. A major objective of this Constitution and By-Laws was to maintain “a pure and virtuous” society “by
avoiding the hierarchic pitfalls and elitist attitudes of the established societies.” The members also decided not to
align this meeting with any other plastic surgery organization. This two-page document was approved at the second
meeting (1956) in Jackson, Mississippi, hosted by Dr. Jim Hendrix. The name of the organization was debated.
One suggested the name, “Plastic University Surgeons” (“P.U.S.”). However, the word “University” itself implied
restriction and was ultimately discarded. The word “Council” was eventually (but not initially) chosen, and had
literally been taken from the Indian usage of the word to indicate an open gathering of all those concerned.The name
of the organization, “The Plastic Surgery Research Council,” was officially adopted at this meeting. It has served
this purpose well.
In 1981, The Peter Gingrass, MD Memorial Award was established by Dr. Ruedi Gingrass on behalf and in
memory of his brother Peter. The award recognizes the medical student or non-plastic surgery resident presenting
the best paper at the annual meeting of The Plastic Surgery Research Council. In 1982, The John F. Crikelair, MD
6
Volume 133, Number 3 (Supplement) • PSRC Abstract Supplement
Research Award was funded by George Crikelair in memory of his son to recognize the best paper at The Plastic
Surgery Research Council by a high school or college student. The Clifford C. Snyder, MD Past-Chairman Award
was established in 1983 by Clifford Synder and funded in part by various past chairmen to recognize the best paper
presented by a Plastic Surgery Resident or Fellow at the Plastic Surgery Research Council annual meeting. In 1997,
The Best Poster Award was established by Dr. Robert Hardesty to recognize the value and contributions of Poster
Presentations at the annual meeting of the Plastic Surgery Research Council. In 2000, the Shenaq International
Research Award for the best paper by a foreign medical school graduate was funded by Dr. Sal Shenaq.
As time passed, the Research Council not only grew in numbers but also in respect among the “other societies
and associations.” The Research Council was formally asked to elect representatives to the American Association of
Medical Colleges, Council of Academic Societies, Plastic Surgery Academic Advisory Council, American College
of Surgeons (Plastic and Maxillofacial Council), American Association of Plastic Surgeons, the Plastic Surgery
Educational Foundation Research Grants Committee, and the Council of Plastic Surgery Organizations. We are also
asked to nominate candidates for the American Board of Plastic Surgery each year.
It is interesting to note that the basic tenants set down in the formative years of the Council have been
maintained as guidelines for The Plastic Surgery Research Council. The original goals and concepts of an open
forum with free discussion of work completed and work in progress continue, and the suggestions of “keep it
young” and meet independently at research institutions continue. Specifically, at age 50 active members become
senior members (with corresponding loss of voting privileges and inability to hold elected office) assuring a
youthful and progressive leadership.
“Of the sixteen founding members of the Plastic Surgery Research Council, five have become Presidents of
the American Society of Plastic and Reconstructive Surgeons (ASPS); four have become Presidents of the American
Association of Plastic Surgery (AAPS); thirteen have been training program directors; three have been ‘Clinician
of the Year’ of the AAPS; and two have received a Special Achievement Award of the ASPS. Eleven have become
Directors of the American Board of Plastic Surgery; four have been Chairmen of the Board; and three have been
Vice-Chairman of the Board”; one received the Nobel Prize in Medicine for his research on transplantation. What a
magnificent heritage.
The Baronio Sheep
From time to time, members and others ask the origin of the sheep drawing that is the PSRC’s official
logo. The following attestation sheds a little light on this subject:
Degli innesti animali. Milan: Dalla Stamperia e Fonderia del Genio, 1804. This landmark work in the
history of plastic surgery details the results of Baronio’s experiments on autogenous skin grafting in animals
at the close of the eighteenth century, the first such study to be carried out in scientifically organized experi-
ments. Baronio (1759–1811), physician and naturalist, records and illustrates the first demonstration of a
successful graft, removing skin from a sheep and transplanting it to a new site on the same sheep within an
hour. The technique was successfully applied in humans some thirteen years later.
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