The Omentum: Research and Clinical Applications

251 Pages·1990·19.192 MB·English

by  Harry S. Goldsmith MD (auth.), Harry S. Goldsmith MD (eds.)

The Omentum
The Omentum
Research and Clinical Applications
Edited by
Harry S. Goldsmith
Springer-Verlag
New York Berlin Heidelberg
London Paris Tokyo Hong Kong
Harry S. Goldsmith, MD
Professor of Surgery
and
Adjunct Professor of Neurosurgery
Boston University School of Medicine
Boston, Massachusetts 02118, USA
Library of Congress Cataloging-in-Publication Data
International Conference on the Omentum (1st: 1988 : Research
Triangle Park, N.C.)
The omentum : research and clinicial application : proceedings of
the First International Conference on the Omentum / sponsored by the
Surgical Rehabilitation Foundation, Maclean, VA, the National
Organization of Disability, Washington, DC, and Glaxo Inc., Research
Triangle Park, NC, USA and held in Research Triangle Park, North
Carolina, October 28-31, 1988 : edited by Harry S. Goldsmith.
p. cm.
Includes bibliographical references.
ISBN-l3: 978-1-4612-8011-8 e-ISBN-13: 978-1-4612-3436-4
DOl: 10.1007/978-1-4612-3436-4
1. Omentum-Transplantation-Congresses. I. Goldsmith, Harry 5.,
1929- II. Surgical Rehabilitation Foundation. III. National
Organization of Disability (U.S.) IV. Glaxo, Inc. V. Title.
[DNLM: 1. Omentum-congresses. WI 575 1610 1988]
RD124.5.I57 1988
617.5'58-dc20
DNLM/DLC 90-9984
Printed on acid-free paper.
© 1990 Springer-Verlag New York Inc.
Softcover reprint of the hardcover 1s t edition 1990
All rights reserved. This work may not be translated or copied in whole or in part without
the written permission of the publisher (Springer-Verlag New York, Inc., 175 Fifth Avenue,
New York, NY 10010, USA), except for brief excerpts in connection with reviews or scholar
ly analysis. Use in connection with any form of information storage and retrieval, electronic
adaptation, computer software, or by similar or dissimilar methodology now known or
hereafter developed is forbidden.
The use of general descriptive names, trade names, trademarks, etc., in this publication,
even if the former are not especially identified, is not to be taken as a sign that such names,
as understood by the Trade Marks and Merchandise Marks Act, may accordingly be used
freely by anyone.
While the advice and information in this book are believed to be true and accurate at the
date of going to press, neither the authors nor the editors nor the publisher can accept any
legal responsibility for any errors or omissions that may be made. The publisher makes no
warranty, express or implied, with respect to the material contained herein.
Camera-ready copy provided by the editor.
9 8 7 6 5 4 3 2 1
Contents
List of Contributors vii
Arthur M. Vineb erg MD 1903-1988: A pioneer in the use of
the omentum 1
H. S. Goldsmith
Historical images and ideas about the greater omentum 5
D. Liebermann-Meffert
Anatomy of the greater and lesser omentum in the mouse with
some physiological implications 19
K. Dux
Angiogenesis and the greater omentum 45
R. Williams
Can transected spinal cord axons be bribed into regeneration? 63
J. c. de la Torre and H. S. Goldsmith
Vasoactive neurochemicals in the omentum: Implications for
CNS injury 75
T. K. McIntosh and H. S. Goldsmith
Experimental studies of omentum-derived neurotrophic factors 83
G. C. Siek, J. K. Marquis and H. S. Goldsmith
Time and dose-dependent profile of omental angiogenic lipid
factor on bone repair 97
B. Huber, A. Juhn, D. Mohler, R. Barth, T. Ullman, C. Baker and
J. M. Lane
An rCBF follow-up study in stroke patients after omentum
transposition to the brain 109
G. Rosadini, M. Cossu, H. S. Goldsmith, A. Pau, G. Rodriguez,
E. S. Viale, S. Turtas and C. L. Viale
Omental transposition to bypass the blood brain barrier for
delivery of chemotherapeutic agents to malignant brain tumours:
preclinieal investigation 117
M. S. Berger, P. R. Weinstein, H. S. Goldsmith, R. Hattner,
E. Z. Longa and B. Perira
v
vi Contents
The omentum: Present status and future application 131
H. S. Goldsmith
Omental transposition to the brain: Experimental and human
applications 147
J. Abraham
Cerebral revascularization by omental graft for moyamoya
disease 159
S. Miyamoto, H. Kikuchi, J. Karasawa and 1. Nagata
Omental transposition for treating the sequelae of viral
encephalitis: A surgical and follow-up study of 32 cases . 165
Wu Wei Lei, Q. G. Meng and S. Qing Xu
Experimental and clinical use of omental transposition for
spinal cord pathology 173
M. S. Zhan, H. C. Jia, R. G. Wei, Q. T. Jiang, Y. C. You, Q. Ji, Z. Xu,
Y. He, J. Liu, G. Lu, J. Liu, Z. Xu, J. Ki, J. Zhang and W. Huo
Omental transplantation for Buerger's disease 187
A. Nishimura
Lumbo-omental shunt for treatment of communicating
hydrocephalus 207
B. Levander and J. Wennerstrand
The anaesthetic management of patients undergoing omental
transposition to the central nervous system 223
L. Barsoum and P. Bayly
Summation: Ideas presented and lessons learned. The omentum:
A physiological generating system of basic physiology. The
need for its application to myocardial vascularization and other
clinical problems 229
W. Regelson
Perspectives in scientific research: A speech to participants at
the 1st International Conference on the Omentum 241
D. Burkitt
Index 247
Contributors
Editor
Harry S. Goldsmith Department of Surgery, Boston University School of
Medicine, 75 East Newton Street, Boston, Massachusetts
02118, USA
Contributors
J. Abraham Department of Neurological Sciences, Christian Medical
College and Hospital, Vellore 632004, India
C. Baker The Hospital for Special Surgery, 535 East 70th Street,
New York 10021, USA
L. Barsoum Brook General Hospital, Shooters Hill, Woolwich,
London, SE184LW, UK
R. Barth The Hospital for Special Surgery, 535 East 70th Street,
New York 10021, USA
P. Bayly King's College Hospital, Denmark Hill, London, SE59RS,
UK
M. S. Berger Department of Neurosurgery, Rl-20, University Hospital,
1959 NE Pacific, Seattle, Washington 98194, USA
D. P. Burkitt Hartwell Cottage, Wells Road, Bisley, Gloucester,
GL6 7AG, UK
M. Cossu Institute of Neurosurgery, University of Genoa Medical
School, Genoa, Italy
K. Dux Department of Tumour Biology, Institute of Oncology, UL.
Wawelaska 15, 00-973 Warszawa, Poland
R. Hattner Nuclear Medicine Section, University of California,
San Francisco, California, USA
Y. He Department of Neurosurgery, 1st Hospital, Beijing Medical
University, Beijing, People's Republic of China
B. Huber The Hospital for Special Surgery, 535 East 70th Street,
New York 10021, USA
vii
viii Contributors
W. Huo Department of Neurosurgery, 1st Hospital, Beijing Medical
University, Beijing, People's Republic of China
Q. Ji Department of Anatomy, Basic Medical College, Beijing
Medical University, Beijing, People's Republic of China
H. C. Jia Department of Orthopaedics, Water Resources Hospital of
Beijing, Beijing, People's Republic of China
Q. T. Jiang Department of Orthopaedics, PLA 309 Hospital, Beijing,
People's Republic of China
A. Juhn The Hospital for Special Surgery, 535 East 70th Street,
New York 10021, USA
H. Kikuchi Department of Neurosurgery, Kyoto University Medical
School, Kyoto, Japan
J. M. Lane The Hospital for Special Surgery, 535 East 70th Street,
New York 10021, USA
B. Levander Department of Neurosurgery, The Karolinska Institute,
Stockholm, Sweden
Wu Wei Lie Xin-Hua Hospital, Shanghai Second Medical University,
1665 Kong Jiang Road, Shanghai, People's Republic of
China
D. Liebermann-Meffert Department of Surgery, University Hospital, Spitalstr. 21,
CH-4031 Basel, Switzerland
J. Liu Department of Anatomy, Veterinary College, Beijing
Agricultural University, Beijing, People's Republic of
China
E. Z. Longa Instituto de Cirugia Experimental, Facultadde Medicine,
Universidad Central de Venezuela, Caracas, Venezuela
G. Lu Department of Anatomy, Veterinary College, Beijing
Agricultural University, Beijing, People's Republic of
China
T. K. McIntosh Department of Surgery, Surgical Research Center,
University of Connecticut Health Center, Farmington,
CT 06033, USA
J. K. Marquis Department of Pharmacology and Experimental
Therapeutics, Boston University School of Medicine,
Boston, MA 02118, USA
Q. G. Meng Department of Neurosurgery, Shanghai Xin-Hua Hospital,
Shanghai Second Medical University, Shanghai, People's
Republic of China
Contributors ix
S. Miyamoto Department of Neurosurgery, Kyoto University Medical
School, 54 Kawaharcho Shongoin, Sakyo-ku, Kyoto 606,
Japan
D. Mohler The Hospital For Special Surgery, 535 East 70th Street,
New York 10021, USA
I. Nagata Department of Neurosurgery, Kyoto University Medical
School, Kyoto, Japan
A. Nishimura Nikko Memorial Hospital, 1-5-13 Shintomi-cho, Muroran
051, Japan
A. Pau Institute of Neurology, University of Modena Medical
School, Modena, Italy
B. Perira Neuro-vascular Laboratory, Department of Neurosurgery,
University of California, San Francisco, California, USA
W. Regelson Medical College of Virginia, Virginia Commonwealth
University, Virginia, USA
G. Rodriguez Institute of Neurophysiopathology, University of Genoa,
Ospedale San Martino, 16132 Genoa, Italy
G. Rosadini Institute of Neurophysiopathology, University of Genoa,
Ospedale San Martino, 16132 Genoa, Italy
G. C. Siek Department of Pharmacology, Boston University School
of Medicine, 75 East Newton Street, Boston, Massachusetts
02118, USA
J. C. de la Torre University of Ottawa Health Sciences, Division of
Neurological Surgery, 451 Smyth Road, Ottawa, Ontario,
K1H 8M5, Canada
S. Turtas Institute of Neurology, University of Sassari Medical
School, Sassari, Italy
T. Ullman The Hospital for Special Surgery, 535 East 70th Street,
New York 10021, USA
E. S. Viale Institute of Neurology, University of Genoa Medical
School, Genoa, Italy
G. L. Viale Institute of Neurology, University of Genoa Medical
School, Genoa, Italy
R. G. Wei Department of Neurosurgery, PLA 514 Hospital, Beijing,
People's Republic of China
P. Weinstein Department of Neurological Surgery, University of
California, San Francisco, California, USA
x Contributors
J. Wennerstrand Department of Neurosurgery, The Karolinska Institute,
Stockholm, Sweden
R. Williams Academic Surgical Unit, QEQM Wing, St Mary's
Hospital, Praed Street, London W2 1NY, UK
Z.Xu Department of Neurosurgery, 1st Hospital, Beijing Medical
University, Beijing, People's Republic of China
Y. C. You Department of Neurosurgery, 1st Hospital, Beijing Medical
University, Beijing, People's Republic of China
M. S. Zhan Department of Neurosurgery, 1st Hospital, Beijing Medical
University, Beijing, People's Republic of China
Arthur M. Vineberg, MD, 1903-1988:
A pioneer in the use of the omentum
Dr Arthur M. Vineberg was born in Montreal, Canada, in 1903. His entire academic
career was spent at McGill University in Montreal, an institution which he served
well throughout his life. After graduating from McGill with a Bachelor of Science
degree in 1924, he immediately entered their medical school from which he
graduated with an MD degree in 1928. An early indication of Dr Vineberg's
tremendous dedication and capacity to work was the fact that while going through
the McGill medical school from 1924-1928, he was also studying at its Graduate
School of Biochemistry where he had to do his work mainly at night, weekends,
and during vacation periods. He received his Masters in Science degree in
biochemistry from McGill University at the same time as the institution conferred
upon him its MD degree.
Dr Vineberg's first year of surgical training was carried out at the Columbia
Division of Bellevue Hospital in New York City from 1928 to 1929. Except for this
short period away from Canada, his entire surgical training was carried out at
the Royal Victoria Hospital in Montreal. It is of great interest to see again the
tremendous productivity and drive of Dr Vineberg by noting that while a resident
in surgery at the Royal Victoria Hospital from 1929-1933, he was also a student
in the Graduate School of Physiology at McGill, receiving his PhD degree in
experimental physiology at the same time as he completed his surgical training.
Following his surgical training, Dr Vineberg practised clinical surgery at several
hospitals in Montreal while at the same time teaching anatomy at McGill. In 1942
he entered active service with the Royal Canadian Army Medical Corp, rising
to the rank of Major. While in the army he met and married a young woman,
Ann Buckley, whom he said he loved from the moment he saw her. It was a love
that never diminished throughout either of their lives.
At the end of the Second World War, Dr Vineberg returned to Montreal where
he became interested in the revascularization of the human heart. He began highly
imaginative experiments in which he demonstrated that the internal mammary
artery could be placed within the muscle of the heart with the subsequent
development of new blood vessels that arose from the implanted artery and
penetrated directly into the myocardial wall. He also showed that when the
omentum was placed upon the heart, omental blood vessels invaded the
underlying cardiac tissue.
1