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The Journals of Gerontology. Series A: Biological Sciences and Medical Sciences 2005: Vol 60A Table of Contents PDF

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Journal of Gerontology: BIOLOGICAL SCIENCES Contents of Volume 60A VOLUME 60A JANUARY 2005 NUMBER 1 Acknowledgment of Reviewers Down-Regulation of a Forkhead Transe alien Factor, FOXO3a, Accelerates Cellular Senescence in Human Dermal Fibroblasts Hyun Kyoung Kim, Yu Kyoung Kim, In-Hwan Song, Suk-Hwan Baek, Seung-Rock Lee, Jung Hye Kim, and Jae-Ryong Kim Shared Phenotypes Among Segmental Progeroid Syndromes Suggest Underlying Pathways of Aging Anne C. Hofer, Rosie T. Tran, Owais Z. Aziz, Woodring Wright, Guiseppe Novelli, Jerry Shay, and Marc Lewis Aging Elevates Basal Adenosine Monophosphate-Activated Protein Kinase (AMPK) Activity and Eliminates Hypoxic Activation of AMPK in Mouse Liver . ......dacob D. Mulligan, Asensio A. Gonzalez, Reetu Kumar, Ashley J. Davis, and Kurt W. Saupe Effects of Long-Term Caloric Restriction on Early Steps of the Insulin-Signaling System in Mouse Skeletal Muscle Danila P. Argentino, Fernando P. Dominici, Khalid Al-Regaiey, Michael §. Bonkowski, Andrzej Bartke, and Daniel Turyn 4 Note on Age-Related Biomarkers. Robert A. Weale Accumulation of Dolichol in Older Tissues Satisfies the Proposed Criteria To Be Qualified a Biomarker of Aging Ilaria Parentini, Gabriella Cavallini, Alessio Donati, Zina Gori, and Ettore Bergamini Oral Administration of Melatonin to Old Ring Doves (Streptopelia risoria) Increases Plasma Levels of Melatonin and Heterophil Phagocytic Activity eee eee eee. M” del Pilar Terron, Sergio D. Paredes, Carmen Barriga, Eduardo Ortega, Russel J. Reiter, and Ana B. Rodriguez Instructions to Authors VOLUME 60A FEBRUARY 2005 NUMBER 2 Letter to the Editor. All Hype, No Hope? Excessive Pessimism in the “Anti-Aging Medicine” Special Sections............ Alexander A. Fisher, Michael W. Davis, and David G. Le Couteur Guest Editors’ Response . . Leonard Hayflick, S. Jay Olshansky, and Thomas T. Perls Perspectives Article. Regaining Lost Youth: The Controversial and Colorful Beginnings of Hormone Replacement Therapy in Aging Arnold Kahn Differences in Size, Strength, and Power of Upper and Lower Body Muscle Groups in Young and Older Men Darren G. Candow and Philip Chilibeck Brief Food Restriction in Old Animals Decreases Triglyceride Content and Insulin-Stimulated Triglyceride Synthes Michelle Z. Tucker and Lorraine P. Turcotte Selective Atrophy of Left Hemisphere and Frontal Lobe of the Brain in Old Men Zu Y. Shan, Jing Z. Liu, Vinod Sahgal, Bin Wang, and Guang H. Yue Lack of Effect of Caloric Restriction on Bioenergetics and Reactive Oxygen Species Production in Intact Rat Hepatocytes............... Adrian J. Lambert and Brian J. Merry 175 Instructions to Authors .. . 181 VOLUME 60A MARCH 2005 NUMBER 3 4 Complex Dietary Supplement Extends Longevity of Mice ... . Jennifer A. Lemon, Douglas R. Boreham, and C. David Rollo Polymorphisms in the Oxidized Low-Density Lipoprotein Receptor-1 Gene and Risk of Alzheimer’s Disease Alessia D’Introno Vincenzo Solfrizzi, Anna M. Colacicco, Cristiano Capurso, Francesco Torres, Sabrina A. Capurso, Antonio Capurso, and Francesco Panza Mismatch Repair System and Aging: Microsatellite Instability in Peripheral Blood Cells From Differently Aged Participants... . Simona Neri, Alessandro Gardini, Andrea Facchini, Fabiola Olivieri, Claudio Franceschi, Giovanni Ravaglia, and Erminia Mariani Evidence for Down-Regulation of Phosphoinositide 3-Kinase/Akt/Mammalian Target of Rapamycin (PI3K/Akt/mTOR)-Dependent Translation Regulatory Signaling Pathways in Ames Dwarf Mice ‘ Zelton Dave Sharp and Andrzej Bartke Mutation Screening and Association Study of the Neprilysin Gene in Sporadic Alzheimer’s Disease in Chinese Persons Jiajun Shi, Sizhong Zhang, Mouni Tang, Cui Ma, Jinghua Zhao, Tao Li, Xiehe Liu, Yan Sun, Yangbo Guo, Haiying Han, Yongxin Ma, and Zhenhuan Zhao Effect of Exercise Training on Peak Aerobic Power, Left Ventricular Morphology, and Muscle Strength in Healthy Older Women Mark Haykowsky, Jonathan McGavock, Isabelle Vonder Muhll, Matthew Koller, Sandra Mandic, Robert Welsh, and Dylan Taylor Aging Effects on the Metabolic and Cognitive Energy Cost of Interlimb Coordination William A. Sparrow, Suzanne Parker, Brendan Lay, and Michael Wengier 312 Instructions to Authors 320 VOLUME 60A APRIL 2005 NUMBER 4 Figure Corrections. Mapping Development-Related and Age-Related Chromatin Remodeling by a High Throughput ChIP-HPLC Approach... . Valya R. Russanova, Tazuko H. Hirai, Andrei V. Tchernov, and Bruce H. Howard 411 Rapid Communication. National Institute on Aging Microarray Facility—Resources for Gerontology Research Nancy L. Nadon, David Mohr, and Kevin G. Becker 413 Electrical Stimulation Attenuates Denervation and Age-Related Atrophy in Extensor Digitorum Longus Muscles of Old Rats Douglas E. Dow, Robert G. Dennis, and John A. Faulkner Age-Related Decline in Actomyosin Function ay See evens Ewa Prochniewicz, David D. Thomas, and LaDora V. Thompson Journal of Gerontology: BIOLOGICAL SCIENCES Contents of Volume 60A VOLUME 60A JANUARY 2005 NUMBER 1 Acknowledgment of Reviewers Down-Regulation of a Forkhead Transe alien Factor, FOXO3a, Accelerates Cellular Senescence in Human Dermal Fibroblasts Hyun Kyoung Kim, Yu Kyoung Kim, In-Hwan Song, Suk-Hwan Baek, Seung-Rock Lee, Jung Hye Kim, and Jae-Ryong Kim Shared Phenotypes Among Segmental Progeroid Syndromes Suggest Underlying Pathways of Aging Anne C. Hofer, Rosie T. Tran, Owais Z. Aziz, Woodring Wright, Guiseppe Novelli, Jerry Shay, and Marc Lewis Aging Elevates Basal Adenosine Monophosphate-Activated Protein Kinase (AMPK) Activity and Eliminates Hypoxic Activation of AMPK in Mouse Liver . ......dacob D. Mulligan, Asensio A. Gonzalez, Reetu Kumar, Ashley J. Davis, and Kurt W. Saupe Effects of Long-Term Caloric Restriction on Early Steps of the Insulin-Signaling System in Mouse Skeletal Muscle Danila P. Argentino, Fernando P. Dominici, Khalid Al-Regaiey, Michael §. Bonkowski, Andrzej Bartke, and Daniel Turyn 4 Note on Age-Related Biomarkers. Robert A. Weale Accumulation of Dolichol in Older Tissues Satisfies the Proposed Criteria To Be Qualified a Biomarker of Aging Ilaria Parentini, Gabriella Cavallini, Alessio Donati, Zina Gori, and Ettore Bergamini Oral Administration of Melatonin to Old Ring Doves (Streptopelia risoria) Increases Plasma Levels of Melatonin and Heterophil Phagocytic Activity eee eee eee. M” del Pilar Terron, Sergio D. Paredes, Carmen Barriga, Eduardo Ortega, Russel J. Reiter, and Ana B. Rodriguez Instructions to Authors VOLUME 60A FEBRUARY 2005 NUMBER 2 Letter to the Editor. All Hype, No Hope? Excessive Pessimism in the “Anti-Aging Medicine” Special Sections............ Alexander A. Fisher, Michael W. Davis, and David G. Le Couteur Guest Editors’ Response . . Leonard Hayflick, S. Jay Olshansky, and Thomas T. Perls Perspectives Article. Regaining Lost Youth: The Controversial and Colorful Beginnings of Hormone Replacement Therapy in Aging Arnold Kahn Differences in Size, Strength, and Power of Upper and Lower Body Muscle Groups in Young and Older Men Darren G. Candow and Philip Chilibeck Brief Food Restriction in Old Animals Decreases Triglyceride Content and Insulin-Stimulated Triglyceride Synthes Michelle Z. Tucker and Lorraine P. Turcotte Selective Atrophy of Left Hemisphere and Frontal Lobe of the Brain in Old Men Zu Y. Shan, Jing Z. Liu, Vinod Sahgal, Bin Wang, and Guang H. Yue Lack of Effect of Caloric Restriction on Bioenergetics and Reactive Oxygen Species Production in Intact Rat Hepatocytes............... Adrian J. Lambert and Brian J. Merry 175 Instructions to Authors .. . 181 VOLUME 60A MARCH 2005 NUMBER 3 4 Complex Dietary Supplement Extends Longevity of Mice ... . Jennifer A. Lemon, Douglas R. Boreham, and C. David Rollo Polymorphisms in the Oxidized Low-Density Lipoprotein Receptor-1 Gene and Risk of Alzheimer’s Disease Alessia D’Introno Vincenzo Solfrizzi, Anna M. Colacicco, Cristiano Capurso, Francesco Torres, Sabrina A. Capurso, Antonio Capurso, and Francesco Panza Mismatch Repair System and Aging: Microsatellite Instability in Peripheral Blood Cells From Differently Aged Participants... . Simona Neri, Alessandro Gardini, Andrea Facchini, Fabiola Olivieri, Claudio Franceschi, Giovanni Ravaglia, and Erminia Mariani Evidence for Down-Regulation of Phosphoinositide 3-Kinase/Akt/Mammalian Target of Rapamycin (PI3K/Akt/mTOR)-Dependent Translation Regulatory Signaling Pathways in Ames Dwarf Mice ‘ Zelton Dave Sharp and Andrzej Bartke Mutation Screening and Association Study of the Neprilysin Gene in Sporadic Alzheimer’s Disease in Chinese Persons Jiajun Shi, Sizhong Zhang, Mouni Tang, Cui Ma, Jinghua Zhao, Tao Li, Xiehe Liu, Yan Sun, Yangbo Guo, Haiying Han, Yongxin Ma, and Zhenhuan Zhao Effect of Exercise Training on Peak Aerobic Power, Left Ventricular Morphology, and Muscle Strength in Healthy Older Women Mark Haykowsky, Jonathan McGavock, Isabelle Vonder Muhll, Matthew Koller, Sandra Mandic, Robert Welsh, and Dylan Taylor Aging Effects on the Metabolic and Cognitive Energy Cost of Interlimb Coordination William A. Sparrow, Suzanne Parker, Brendan Lay, and Michael Wengier 312 Instructions to Authors 320 VOLUME 60A APRIL 2005 NUMBER 4 Figure Corrections. Mapping Development-Related and Age-Related Chromatin Remodeling by a High Throughput ChIP-HPLC Approach... . Valya R. Russanova, Tazuko H. Hirai, Andrei V. Tchernov, and Bruce H. Howard 411 Rapid Communication. National Institute on Aging Microarray Facility—Resources for Gerontology Research Nancy L. Nadon, David Mohr, and Kevin G. Becker 413 Electrical Stimulation Attenuates Denervation and Age-Related Atrophy in Extensor Digitorum Longus Muscles of Old Rats Douglas E. Dow, Robert G. Dennis, and John A. Faulkner Age-Related Decline in Actomyosin Function ay See evens Ewa Prochniewicz, David D. Thomas, and LaDora V. Thompson Is the Vall6Ala Manganese Superoxide Dismutase Polymorphism Associated With the Aging Process? Ee ae Mar istela Taufei A/essandra Peres, Vanessa Moraes de Andrade, Graziela de Oliveira, Gustavo Sd Margo Etiene Pazzato do Canto, Adriana Ritter dos Santos, Moisés E. Bauer, and Ivana Beatrice Manica da Cru Muscular Performances at the Ankle Joint in Young and Elderly Men .... Emilie Simoneau, Alain Martin, and Jacques Van Hoecke c-Kit Expression and Stem Cell Factor-Induced Hematopoietic Cell Proliferation Are Up-Regulated in Aged B6D2F1 Mice Aleah L. Smith, Felicia M. Ellison, J. Philip McCoy, Ji Instructions to Authors VOLUME 60A MAY 2005 NUMBER 5 Functional Analysis of MRG-1: The Ortholog of Human MRGIS5 in Caenorhabditis elegans ......... . . . . Abdullah Oleun, Tetyana Aleksenk Olivia M. Pereira-Smith, and Demetrios K. Vassilatis Counting the Calories: The Role of Specific Nutrients in Extension of Life Span by Food Restriction. . . . Matthew D. W. Piper, William Mai and l Mdad Par {} ave An Immune Risk Phenotype, Cognitive Impairment, and Survival in Very Late Life: Impact of Allostatic Load in Swedish Octogenarian and Nonagenarian Humans Anders Wikby, Frederick Ferguson, Rosalyn Forsey, Julie Thompson, Jan Strindhal Sture Léferen, Bengt-Olof Nilsson, Jan Ernerudh, Graham Pawelec, and Boo Johanssoi Predictors of Transitions in Vitality: The Italian Longitudinal Study on Aging . Nadia Minicuci, Chiara Marzari, Stefania Ma Marianna Noale, Antonella Senesi, and Gaetano Crepaldi Review Article. Disentangling the Genetic Determinants of Human Aging: Biological Age as an Alternative to the Use of Survival Measures David Karasik, Serkalem Demissie, L. Adrienne Cupples, and Douglas P. Kiel Instructions to Authors VOLUME 60A JUNE 2005 NUMBER 6 Letter to the Editor. On the Possible Use of Annual Killifishes as Models for Aging Research: A Comment on Herrera and Jagadeeswaran Alessandro Cellerino Lecture. Genes, Phenes, and Dreams of Immortality: The 2003 Kleemeier Award Lecture .............. Thomas E. Johnson Caloric Restriction Decreases Survival of Aged Mice in Response to Primary Influenza Infection Gini Elizabeth M. Gardner The Comet Assay Approach to Senescent Human Diploid Fibroblasts Identifies Different Phenotypes and Clarifies Relationships Among Nuclear Size, DNA Content, and DNA Damage Alessandra Mocali, Lisa Giovannelli, Piero Dolara, and Francesco Paoletti Involvement of Nitric Oxide-Mediated Intrinsic Pathway Signaling in Age-Related Increase in Germ Cell Apoptosis in Male Brown-Norway Amiya P. Sinha Hikim, Yanira Vera, Dolores Vernet, Mark Castanares Maruja Diaz-Romero, Monica Ferrini, Ronald S. Swerdloff. Nestor F. Gonzalez-Cadavid, and Christina Wan: Effects of Human Na+/Dicarboxylate Cotransporter 3 on the Replicative Senescence of Human Embryonic Lung Diploid Fibroblasts Xiangmei Chen, Dongwei Cao, Jianzhong Wang, Li Yuan, Zhe Feng, Bo Fu, Quan Hong, Xiaojie Zhang, Xueyuan Bai, Yang Lu, and Rui Ding Age-Related Changes of Mitochondrial DNA Content and Mitochondrial Genotypic and Phenotypic Alterations in Rat Hind-Limb Skeletal Muscles Vito Pesce, Antonella Cormio, Flavio Fracasso, Angela M. §. Lezza, Palmiro Cantatore, and Maria Nicola Gadaleta Instructions to Authors VOLUME 60A JULY 2005 NUMBER 7 Platelet Characteristics Change With Aging: Role of Estrogen Receptor 6 . . ah Muthuvel Jayachandran, Krzysztof Karnicki, Randall §. Miller, Whyte G. Owen, Kenneth S. Korach, and Virginia M. Mille) Early-Senescing Human Skin Fibroblasts Do Not Demonstrate Accelerated Telomere Shortening... .. . . . Marina Ferenac, Denis FPOe LANCECE Miljenko Huzak, Olivia M. Pereira-Smith, and Ivica Rubelj Mitochondrial Pathway Is Responsible for Aging-Related Increase of Tubular Cell Apoptosis in Renal Ischemia/Reperfusion Injury Zi Qiao, Xiangmei Chen, Di Wu, Rui Ding, Jianzhong Wang, Quan Hong, Suozhu Shi, Jianjun Li, Yuansheng Xie, Yang Lu, and Zhaoxia Wang Evaluation of Movement Speed and Reaction Time as Predictors of All-Cause Mortality in Men E. Jeffrey Metter, Mathew Schrage Luigi Ferrucci, and Laura A. Talbot Effects of Age and Caloric Restriction on Lipid Peroxidation: Measurement of Oxidative Stress by F2-Isoprostane Levels Walter F. Ward Wenbo Qi, Holly Van Remmen, William E. Zackert, L. Jackson Roberts Il, and Arlan Richardson Decrease of Transthyretin Synthesis at the Blood—Cerebrospinal Fluid Barrier of Old Sheep .......... Ruo L. Chen, Senarath B. P. Athauda Nouhad A. Kassem, Yi Zhang, Malcolm B. Segal, and Jane E. Preston Instructions to Authors VOLUME 60A AUGUST 2005 NUMBER 8 Commentary on Recently Published Articles. A Comment on the Comment: Relevance of Nonhuman Primate Dietary Restriction to Aging in Humans Noni L. Bodkin, Heidi K. Ortmeyer, and Barbara C. Hansen Individual Fecundity and Senescence in Drosophila and Medfly............. Vassili N. Novoseltsev, Robert Arking James R. Carey, Janna A. Novoseltseva, and Anatoli 1. Yashin Myocardial Heat Shock Protein 70 Expression in Young and Old Rats After Identical Exercise Programs is . . Joseph W. Starnes, Alafia M. Choilawala, Ryan P. Taylor, Mathew J. Nelson, and Michael D. Delp Coenzyme Q10 Protects From Aging-Related Oxidative Stress and Improves Mitochondrial Function in Heart of Rats Fed a Polyunsaturated Fatty Acid (PUFA)-Rich Diet Julio J. Ochoa, José L. Quiles, Jess R. Huertas, and José Matai Aging Sustains the Hypertrophy-Associated Elevation of Apoptotic Suppressor X-Linked Inhibitor of Apoptosis Protein (XIAP) in Skeletal Muscle During Unloading Parco M. Siu, Emidio E. Pistilli, Michael J. Ryan, and Stephen E. Alway Increased Kinin Levels and Decreased Responsiveness to Kinins During Aging Viviana Pérez, Victoria Velarde, Claudio Acua-Castillo, Christian Gomez, Sumiyo Nishimura, Valeria Sabaj, Robin Walter, and Felipe Sierra The Cathepsin D Gene Exon 2 (C224T) Polymorphism and Sporadic Alzheimer’s Disease in European Populations ....... Cristiano Capurso, Vincenzo Solfrizzi, Alessia D'Introno, Anna M. Colacicco, Sabrina A. Capurso, Franco Mastroianni, Maria Liaci, Gianluigi Vendemiale, Antonio Capurso, and Francesco Panza Instructions to Authors VOLUME 60A SEPTEMBER 2005 NUMBER 9 Cultured Murine Dermal Fibroblast-Like Cells From Senescence-Accelerated Mice as In Vitro Models for Higher Oxidative Stress Due to Mitochondrial Alterations Yoichi Chiba, Yoshinori Yamashita, Masaki Ueno, Hiromi Fujisawa, Kazunori Hirayoshi, Ken-ichi Hohmura, Hidekazu Tomimoto, Ichiro Akiguchi, Mamoru Satoh, Atsuyoshi Shimada, and Masanori Hosokawa 1087 Effects of Alterations of Glomerular Fibrin Deposition on Renal Inflammation in Rats at Different Age Stages Chunsheng Xi, Xiangmei Chen, Xuefeng Sun, Suozhu Shi, Zhe Feng, Jianzhong Wang, Quan Hong, Yang Lu, and Shupeng Lin 1099 Triceps Surae Muscle Power, Volume, and Quality in Older Versus Younger Healthy Men Lene Christiansen, Hans Christian Petersen, Lise Bathum, Henrik Frederiksen, Matt McGue, and Kaare Christensen 1111 Increased Matrix Metalloproteinase-13 Production With Aging by Human Articular Chondrocytes in Response to Catabolic Stimuli Christopher B. Forsyth, Ada Cole, Gillian Murphy, Julia L. Bienias, Hee-Jeong Im, and Richard F. Loeser, Jr. 1118 Review Article. Dietary Restriction in the Nematode Caenorhabditis elegans . . . . Koen Houthoofd, Thomas E. Johnson, and Jacques R. Vanfleteren 1125 Instructions to Authors .. . 1132 VOLUME 60A OCTOBER 2005 NUMBER 10 Commentary. Anti-Aging Medicine: Fallacies, Realities, Imperatives . Michael J. Rae 1223 Authors’ Response to Commentary. Anti-Aging Medicine: Fallacies, Realities, Imperatives Zhihui Li, Xiangmei Chen, Yuansheng Xie, Suozhu Shi, Zhe Feng, Bo Fu, Xiaojie Zhang, Guangyan Cai, Chuanyue Wu, Di Wu, and Yunjuan Gu 1228 The Symmetry of Longevity 3 é .... Lawrence G. Harshman, Hans-Georg Miiller, Xueli Liu, Yue Wang, and James R. Carey 1233 Caloric Restriction Results in Reese’ Mewineston of Peroxisome Proliferator-Activated Receptor Superfamily in Muscle of Normal and Long- Lived Growth Hormone Receptor/Binding Protein Knockout Mice ................... Michal M. Masternak, Khalid A. Al-Regaiey Marc Michael Del Rosario Lim, Michael S. Bonkowski, Jacob A. Panici, Grzegorz K. Przybylski, and Andrzej Bartke 1238 Electrophysiological Analysis of the Effects of Ginkgo Biloba on Visual Processing in Older Healthy Adults ............ Jonathan W. Page, Joy Findley, and Michael A. Crognale 1246 Betaine Suppresses Proinflammatory Signaling During Aging: The Involvement of Nuclear Factor-xB via Nuclear Factor-Inducing Kinase/IxB Kinase and Mitogen-Activated Protein Kinases ... Eun Kyung Go, Kyung Jin Jung, Ji Young Kim, Byung Pal Yu, and Hae Young Chung 1252 Instructions to Authors 1265 VOLUME 60A NOVEMBER 2005 NUMBER 11 The Biological Sciences Section Program at the 57th Annual Meeting of The Gerontological Society of America ........ |S . Michal Jazwinski, Huber R. Warner, Stephen Helfand, Monica Driscoll, David A. Welsh, John Faulkner, Nir Barzilai, Michael Breitenbach, Roger McCarter, W. Ted Brown, Nicholas Greco, John Mountz, and S. Jay Olshansky A New Field Record for Bat Longevity Andrej J. Podlutsky, Alexander M. Khritankov, Nikolai D. Ovodov, and Steven N. Austad The Naked Mole-Rat: A New Long-Living Model for Human Aging Research Rochelle Buffenstein Review Article. Oxidative Aging and Insulin Receptor Signaling . Wulf Drége Prevention of Accelerated Cell Aging in Werner Syndrome Using a p38 hive Activated Protein Kinase Inhibitor Terence Davis, Duncan M. Baird, Michéle F. Haughton, Christopher J. Jones, and David Kipling Effects of Caloric Restriction and Growth Hormone Resistance on the Expression Level of Peroxisome Proliferator-Activated Receptors Superfamily in Liver of Normal and Long-Lived Growth Hormone Receptor/Binding Protein Knockout Mice ... Michal M. Masternak, Khalid A. Al-Regaiey, Marc Michael Del Rosario Lim, Vanesa Jimenez-Ortega, Jacob A. Panici, Michael S$. Bonkowski, John J. Kopchick, and Andrzej Bartke 1394 Aged Rat Myocardium Exhibits Normal Adenosine Receptor-Mediated Bradycardia and Coronary Vasodilation But Increased Adenosine Agonist- Mediated Cardioprotection . . Gentian Kristo, Yukihiro Yoshimura, Byron J. Keith, Robert M. Mentzer, Jr., and Robert D. Lasley 1399 Instructions to Authors . . 1406 VOLUME 60A NUMBER 12 Acknowledgment of Reviewers 1491 Letter to the Editor. Response to C dierins: on Auaina Killifishes Pudur Jagadeeswaran 1492 Peroxisome Proliferator-Activated Receptor 7 Coactivator 1 in Caloric Restriction and Other Models of Longevity ...... J . Christopher Corton and Holly M. Brown-Borg 1494 Housing Density Does Not Influence the Longevity Effect of Caloric Restriction Yuji keno, Gene B. Hubbard, Shuko Lee, Arlan Richardson, Randy Strong, Vivian Diaz, and James F. Nelson 1510 Reference Body Composition in Adult Rhesus Monkeys: Glucoregulatory and Anthropometric Indices Aarthi Raman, Ricki J. Colman, Yu Cheng, Joseph W. Kemnitz, Scott T. Baum, Richard Weindruch, and Dale A. Schoeller 1518 Association of Interleukin-10 Promoter Single Nucleotide Polymorphisms -819 T/C and -592 A/C With Aging Naoko Okayama, Yuichiro Hamanaka, Yutaka Suehiro, Yoshinori Hasui, Junji Nakamura, and Yuji Hinoda 1525 Volume Contents and Index 1530 1532 Journal of Gerontology: MEDICAL SCIENCES Contents of Volume 60A VOLUME 60A JANUARY 2005 NUMBER 1 Acknowledgments Editorial. An Exciting Thought Luigi Ferrucci Review Article. Maximal Aerobic Capacity Testing of Older Adults: A Critical Review Deanna L. Huggett, Denise M. Connelly, and Tom J. Overend Cross-Sectional and Longitudinal Association Between Antihypertensive Medications and Cognitive Impairment in an Elderly Population Thab Hajjar, Heath Catoe, Sherry Sixta, Rebecca Boland, David Johnson, Victor Hirth, Darryl Wieland, and Paul Eleazei Measures of Physical Performance and Risk for Progressive and Catastrophic Disability: Results From the Women’s Health and Aging Study Graziano Onder, Brenda W. J. H. Penninx, Luigi Ferrucci, Linda P. Fried, Jack M. Guralnik, and Marco Pahor Depressive Symptoms and Development of Coronary Heart Disease Events: The Italian Longitudinal Study on Aging ... . Mee eae Chiara Marzari, Stefania Maggi, Enzo Manzato, Carla Destro, Marianna Noale, Daniele Bianchi, Nadia Minicuci, Gino Farchi Marzia Baldereschi, Antonio Di Carlo, Gaetano Crepaldi, and the ILSA Working Group A Prospective Study of the Pressure Ulcer Scale for Healing (PUSH) Energy Cost and Cardiorespiratory Adaptation in the “Get-Up-and-Go” Test in Frail Elderly Women With Postural Abnormalities and in Controls Laurent Brondel, France Mourey, Chrystel Mischis-Troussard, Philippe d’ Athis, and Pierre Pfitzenmeyer Nighttime Oxygen Desaturation and Symptoms of Sleep-Disordered Breathing in Long-Stay Nursing Home Residents Jennifer L. Martin, Aaron K. Mory, and Cathy A. Alessi Influences of Aging on Taste Perception and Oral Somatic Sensation Akiko Fukunaga, Hiroshi Uematsu, and Kumiko Sugimoto Reliability of a Single-Session Isokinetic and Isometric Strength Measurement Protocol in Older Men T. Brock Symons, Anthony A. Vandervoort, Charles L. Rice, Tom J. Overend, and Greg D. Marsh Prognostic Implications of Swallowing Ability in Elderly Patients After Initial Recovery From Stroke a Toshihiko Iwamoto, Sarah Fukuda, Masayuki Kikawada, Masaru Takasaki, and Toshiharu Imamurai Using the FoodEx-LTC to Assess Institutional Food Service Practices Through Nursing Home Residents’ Perspectives on Nutrition Care Bronwynne C. Evans and Neva L. Crogan Letter to the Editor. Rapid Neurological Decline and Death in a 79-Year-Old Woman Andrea Hegglin and Thomas Miinze Letter to the Editor. Insulin Resistance and Cognitive Aging in Long-Lived and Short-Lived Mice Instructions to Authors .. . VOLUME 60A FEBRUARY 2005 NUMBER 2 Letter to the Editor. The Effect of Meals at Different Mealtimes on Blood Pressure and Symptoms in Geriatric Patients With Postprandial Hypotension Alexander A. Fisher, Michael W. Davis, and David G. Le Couteu Authors’ Response : Lilian Vloet and Rene W. M. M. Jansen Tai Chi and Fall Reductions in Older Adults: A Randomized Controlled Trial... . Fuzhong Li, Peter Harmer, K. John Fisher, Edward McAuley, Nigel Chaumeton, Elizabeth Eckstrom, and Nicole L. Wilson Total and Differential White Blood Cell Counts and Their Associations With Circulating Interleukin-6 Levels in Community-Dwelling Older a rearrare: Sean Leng, Qian-Li Xue, Yi Huang, Richard Semba, Paulo Chaves, Karen Bandeen-Roche, Linda Fried, and Jeremy Walston Age-Related Changes in Microvascular Blood Flow and Transcutaneous Oxygen Tension Under Basal and Stimulated Condition . Rajna Ogrin, Peteris Darzins, and Zeinab Khalil Inner City, Middle-Aged African Americans Have Excess Frank and Subclinical Disability Douglas K. Miller, Fredric D. Wolinsky, Theodore K. Malmstrom, Elena M. Andresen, and J. Philip Mille: Prevalence of and Risk Factors for Sarcopenia in Elderly Chinese Men and Women Edith M. C. Lau, Henry S. H. Lynn, Jean W Validation of the Hopkins Medication Schedule To Identify Difficulties in Taking Medications Qian-Li Xue, Carmen Tekwe, and Jason Brandt Grip Strength, Postural Control, and Functional Leg Power in a Representative Cohort of British Men and Women: Associations With Physical Activity, Health Status, and Socioeconomic Conditions Diana Kuh, E. Joan Bassey, Suzanne Butterworth, Rebecca Hardy, Michael E. J. Wadsworth, and the Musculoskeletal Study Team Muscle Coordination During Rapid Force Production by Young and Older Adults ... . Benjamin K. Barry, Stephan Riek, and Richard G. Carson Prevalence and Determinants of Impaired Glucose Metabolism in Frail Elderly Patients: The Belgian Elderly Diabetes Survey (BEDS) Michel P. Hermans, Thierry M. Pepersack, Lionel H. Godeaux, Ingo Beyer, and André P. Tur« Diseases and Impairments as Risk Factors for Onset of Disability in the Older Population in England and Wales: Findings From the Medical Research Council Cognitive Function and Ageing Study Nicola A. Spiers, Ruth J. Matthews, Carol Jagger, Fiona E. Matthews, Chad Boult, Tom G. Robinson, and Carol Brayne Prevalence of Symptomatic Peripheral Arterial Disease, Modifiable Risk Factors, and Appropriate Use of Drugs in the Treatment of Periyheral Arterial Disease in Older Persons Seen in a University General Medicine Clinic Jose Ness, Wilbert S. Aronow Erin Newkirk, and Deanna McDane Predictors of Functional Impairment in Residents of Assisted-Living Facilities: The Maryland Assisted Living Studys Daniel J. Burdick, Adam Rosenblatt, Quincy M. Samus, Cynthia Steele, Alva Baker, Michael Harper, Lawrence Mayer, Jason Brandt, Peter Rabins, and Constantine G. Lyketsos Effect of an Enriched Drink on Cognitive Function in Frail Elderly Person Wendeline Wouters-Wesseling, Lisette W. Wagenaar, Marja Rozendaal, Jan Berend Deijen, Lisette C. de Groot, Jacques G. Bindels, and Wija A. van Staveren Instructions to Authors VOLUME 60A MARCH 2005 NUMBER 3 Letter to the Editor. Stability and Sensitivity of Nursing Home Quality Indicators Bruce E. Robinson Authors’ Response Marilyn J. Rantz, Lanis Hicks, Gregory Petroski, Richard Madsen, David Mehr, Vicki Conn, Mary Zwygart-Stauffacher, and Meridean Maas Muscle Mass, Muscle Strength, and Muscle Fat Infiltration as Predictors of Incident Mobility Limitations in Well-Functioning Older Persons Marjolein Visser, Bret H. Goodpaster, Stephen B. Kritchvesky, Anne B. Newman, Michael Nevitt, Susan M. Rubin, Eleanor M. Simonsick, and Tamara B. Harris, for the Health ABC Study Expanding the Disablement Process Model Among Older Mexican Americans .. M. Kristen Peek, Kushang V. Patel, and Kenneth J. Ottenbacher Randomized Controlied Drug Trials on Very Elderly Subjects: Descriptive and Methodological Analysis of Trials Published Between 1990 and 2002 and Comparison With Trials on Adults Jean-Laurent Le Quintrec, Caselind Bussy, Jean-Louis Golmard, Christian Hervé, Alain Baulon, and Francois Piette Physical Disability Contributes to Caregiver Stress in Dementia Caregivers ... David G. Bruce, Glenys A. Paley, Pamela Nichols, David Roberts, Peter J. Underwood, and Frank Schaper Relationship Between Lung Function and Physical Perforamnce in Disabled Older Women Crystal F. Simpson, Naresh M. Punjabi, Linda Woelfenden, Michelle Shardell, David M. Shade, and Linda P. Fried Fear of Falling and Related Activity Restriction Amogn Middle-Aged African Americans Margaret-Mary G. Wilson, Douglas K. Miller, Elena M. Andersen, Theodore K. Malmstrom, J. Phillip Miller, and Fredric D. Wolinsky Circulating Acute Phase Mediators and Skeletal Muscle Performance in Hospitalized Geriatric Patients Ivan Bautmans, Rose Njemini, Margareta Lambert, Christian Demanet, and Tony Mets Maintenance of Effects of the Home Environment Skill-Building Program for Family Caregivers and Individuals with Alzheimer’s Disease and Related Disorders. . . Laura N. Gitlin, Walter W. Hauck, Marie P. Dennis, and Laraine Winter Apolipoprotein «4: Allele and Problems W ith Orientation Are Associated With a Persistent Decline in Cognition in Community-Dwelling Elderly Persons . Sharon J. Wayne, Bruno J. Vellas, Steven G. Brodie, Philip J. Garry, and Richard N. Baumgartner Reading Aloud and Arithmetic Calcatation iene Frontal Function of People With Dementia Ryuta Kawashima, Katsuo Okita, Ritsumi Yamakazi, Nobumoto Tajima, Hajime Yoshida, Masato Taira, Kazuki Iwata, Takeo Sasaki, Katsujiro Maeyama, Nobuo Usui, and Koji Sugimoto Age, Hormones, and Cognitive Functioning Among Middle-Aged and Elderly Men: Cross-Sectional Evidence From the Massachusetts Aging Study . Stephanie J. Fonda, Rosanna Bertrand, Amy O'Donnell, Christopher Longcope, and John B. McKinlay Swallow Respiratory Patterns ont Aging: Presbyphagia or Dysphagia? Paula Leslie, Michael J. Drinnan, Gary A. Ford, and Janet A. Wilson Endonasal Geometry Changes in Elderly People: Acoustic Rhinometry Measurements Limor Muallen Kalmovich, David Elad, Uri Zaretsky, Abraham Adunsky, Anglea Chetrit, Siegal Sadetzki, Samuel Segal, and Michael Wolf Driving Cessation and Increased Depressive Symptoms David R. Ragland, William A. Satariano, and Kara E. MacLeod Ear Diseases in Elderly Hospital Patients in Nigeria Foluwasayo E. Ologe, Segun Segun-Busari, Ibraheem §. Abdulraheem, and Abdulrahman O. Afolabi Instructions to Authors VOLUME 60A APRIL 2005 NUMBER 4 Use of Hormone Replacement Therapy by Postmenopausal Women After Publication of the Women’s Health Initiative Trial Jose Ness, Wilbert §. Aronow, Erin Newkirk, and Deanna McDanely 460 Treatment With Angiotensin-Converting Enzyme Inhibitors Is Associated With a Reduction in Short-Term Mortality in Older Patients With Acute Ischemic Stroke Giovanni Zuliani, Antonio Cherubini, Stefano Volpato, Anna Rita Atti, Alessandro Ble, Chella Vavalle, Filippo Di Todaro, Claudia Benedetti, Carmelinda Ruggiero, Umberto Senin, and Renato Fellin Effect of Metabolic Syndrome on Heart Attack and Mortality in Mexican-American Elderly Persons: Findings of 7-Year Follow-Up From the Hispanic Established Population fer the Epidemiological Study of the Elderly Max E. Otiniano, Xianglin L. Du, Mario R. Maldonado, Laura Ray, and Kyriakos Markides Type 2 Diabetes Is Negatively Associated With Alzheimer’s Disease Neuropathology Michal Schnaider Beeri, Jeremy M. Silverman, Kenneth L. Davis, Deborah Marin, Hillel Z. Grossman, James Schmeidler, Dushyant P. Purohit, Daniel P. Perl, Michael Davidson, Richard C. Mohs, and Vahram Haroutunian Upper and Lower Limb Muscle Power Relationships in Mobility-Limited Older Adults Seth Herman, Dan K. Kiely, Suzanne Leveille, Evelyn O'Neill, Sharon Cyberey, and Jonathan F. Bean Age and Stepping Limb Performance Differences During a Single-Step Recovery From a Forward Fall Michael L. Madigan and Emily M. Lloyd Sarcopenia Is Related to Physical Functioning and Leg Strength in Middle-Aged Women MaryFran R. Sowers, Mary Crutchfield, Kerry Richards, Margaret K. Wilkin, Anna Furniss, Mary Jannausch, Daowen Zhang, and Melissa Gros Predicting Death in the Nursing Home: Development and Validation of the 6-Month Minimum Data Set Mortality Risk Index Davina Porock, Debra Parker Oliver, Steve Zweig, Marilyn Rantz, David Mehr, Richard Madsen, and Greg Petroski Behavioral Disturbances, Not Cognitive Deterioration, Are Associated With Altered Food Selection in Seniors With Alzheimer’s Disease Carol E. Greenwood, Carolyn Tam, Mae Chan, Karen W. H. Young, Malcolm A. Binns, and Robert van Reekum Aspects of Swallowing in Healthy Dentate Elderly Persons Older Than 80 Years Mineka Yoshikawa, Mitsuyoshi Yoshida, Toshikazu Nagasaki, Keiji Tanimoto, Kazuhiro Tsuga, Yasumasa Akagawa, and Teruki Komatsu Comprehensive Health Status Assessment of Centenarians: Results From the 1999 Large Health Survey of Veteran Enrollees Alfredo J. Selim, Graeme Fincke, Dan R. Berlowitz, Donald R. Miller, Shirley X. Qian, Austin Lee, Zhongxiao Cong, William Rogers, Bernardo J. Selim, Xinhua S. Ren, Avron Spiro Ill, and Lewis E. Kazis Clinical Experience. Aggressive Behavior of Classical Kaposi’s Sarcoma and Coexistence With Angiosarcoma Giovanni Gambassi, Roberto Semeraro, Vincenzo Suma, AnnaMaria Sebastio, and Raffaele Antonelli Incalzi Feasibility and Reliability of Four Pain Self-Assessment Scales and Correlation With an Observational Rating Scale in Hospitalized Elderly Demented Patients ..........: Sophie Pautex, Frangois Herrmann, Paulette Le Lous, Malika Fabjan, Jean-Pierre Michel, and Gabriel Gold Statistical Analysis of Efficacy in Falls Prevention Trials...................... M. Clare Robertson, A. John Campbell, and Peter Herbison Letter to the Editor. Hospital Organization: General Internal Medical and Geriatrics Wards oe Renzo Rozzini, Tony Sabatini, and Marco Trabucchi Rapid Communication. Body Weight Changes in Elderly Psychogeriatric Nursing Home Residents . , ac Kim T. B. Knoops, Erika Slump, Lisette C. P. G. M. de Groot, Wendeline Wouters-Wesseling, Marije L. Brouwer, and Wija A. van Staveren Instructions to Authors VOLUME 60A MAY 2005 NUMBE Special Article. Should the NCEP III Guidelines Be Changed in Elderly and Younger Persons at High Risk for Cardiovascular Events? Wilbert S. Aronow Commentaries and Author’s Response. Aronow’s “Should the NCEP III Guidelines Be Changed in Elderly and Younger Persons at High Risk for Cardiovascular Events?” James §. Goodwin, William R. Hazzard, Victor A. Hirth, Deborah R. Levy, Thomas A. Pearson, Arshag D. Mooradian, lra §. Nash, Margaret-Mary G. Wilson, and Wilbert S. Aronow Patients, Mean Age 70 Years, With Automatic Implantable Cardioverter-Defibrillators Treated With Dual-Chamber Rate Responsive Pacing (DDDR-70) Have a Higher Mortality Than Patients With Backup Ventricular Pacing (VVI-40) at 3.7-Year Follow-Up Rishi Sukhija, Wilbert S. Aronow, Carmine Sorbera, Kiran Yalamanchili, and Martin Cohen, Jack M. Guralnik, and Luigi Ferrucci Inpatient Telemetry Does Not Need To Be Used in the Management of Older Patients Hospitalized With Chest Pain at Low Risk for In-Hospital Coronary Events and Mortality Mohammad A. Saleem, John A. McClung, Wilbert S. Aronow, and Hari Kannam Arterial Pulse Wave Velocity as a Marker of Poor Cognitive Function in an Elderly Community-Living Population Yoshinori Fujiwara, Paulo H. M. Chaves, Ryutaro Takahashi, Hidenori Amano, Hiroto Yoshida, Shu Kumagai, Koji Fujita, Dou Gui Wang, and Shoji Shinkai Dietary Variety Predicts Low Body Mass Index and Inadequate Macronutrient and Micronutrient Intakes in Community-Dwelling Older Adults Susan B. Roberts, Cheryl L. Hajduk, Nancy C. Howarth, Robert Russell, and Megan A. McCrory Psychotropic Medications and Risk for Falls Among Community-Dwelling Frail Older People: An Observational Study Francesco Landi, Graziano Onder, Matteo Cesari, Christian Barillaro, Andrea Russo, Roberto Bernabei, on Behalf of the Silver Network Home Care Study Group Effect of Age on Characteristics of Forward and Backward Gait at Preferred and Accelerated Walking Speed Yocheved Laufer Hyperkyphotic Posture and Poor Physical Functional Ability in Older Community-Dwelling Men and Women: The Rancho Bernardo Study Deborah M. Kado, Mei-Hua Huang, Elizabeth Barrett-Connor, and Gail A. Greendale Optimal Load for Increasing Muscle Power During Explosive Resistance Training in Older Adults Nathan J. de Vos, Nalin A. Singh, Dale A. Ross, Theodora M. Stavrinos, Rhonda Orr, and Maria A. Fiatarone Singh Rapid Communication. The Effect of Nandrolone Decanoate on Bone Mineral Density, Muscle Mass, and Hemoglobin Levels in Elderly Women With Osteoporosis: A Double-Blind, Randomized, Placebo-Controlled Clinical Trial Alberto Frisoli, Jr., Paulo H. M. Chaves, Marcelo Medeiros Pinheiro, and Vera Lucia Szejnfeld Use of Proxy Respondents and Accuracy of Minimum Data Set Assessments of Activities of Daily Terry Y. Lum, Wen-Chieh Lin, and Robert L. Kane Early Event-Related Potential Changes During Working Memory Activation Predict Rapid Decline in Mild Cognitive Impairment Pascal Missonnier, Gabriel Gold, Lara Fazio-Costa, Jean-Pierre Michel, Reinhild Mulligan, Agnés Michon, Vicente Ibanez, and Panteleimon Giannakopoulos 660 A Nonspeech Investigation of Tongue Function in Parkinson’s Disease Megan J. McAuliffe, Elizabeth C. Ward, Bruce E. Murdoch, and Anna M. Farrell 667 Instructions to Authors 675 1609 VOLUME 60A JUNE 2005 NUMBER 6 Guest Editorial. Closing in on a Killer: Anemia in Elderly People... . Dan L. Longo 727 Impact of Anemia and Cardiovascular Disease on Frailty Status of Community-Dwelling Older Women: The Women’s Health and Aging Studies I Paulo-H. M. Chaves, Richard D. Semba,Sean X. Leng, Richard C. Woodman, Luigi Ferrucci, Jack M. Guralnik, and Linda P. Fried ieee Avticle: Sea Tiareeees, ae ARRON MOUOIRE os ooo ore bck siicals we x ie eK Aled wa oe OM ENA ew ene wares Larry W. Baum Do Depressive Symptoms Predict Alzheimer’s Disease and Dementia? Jennifer L. Gatz, Suzanne L. Tyas, Philip St. John, and Patrick Montgomery Delirium Superimposed on Dementia in a Community-Dwelling Managed Care Population: A 3-Year Retrospective Study of Occurrence, Costs, Donna M. Fick,Ann M. Kolanowski, Jennifer L. Waller, and Sharon K. Inouye ss Oneal olic oURe ace aera oranees ee Susan L. Greenspan, Neil M. Resnick, and Robert A, Parker Association Between Physical Activity, Physical Performance, and Inflammatory Biomarkers in an Elderly Population: The InCHIANTI Study Roberto Elosua,Benedetta Bartali, Jose M. Ordovas, Anna M. Corsi, Fulvio Lauretani, and Luigi Ferrucci, on Behalf of the InCHIANTI Investigators A Randomized Controlled Trial of High Versus Low Intensity Weight Training Versus General Practitioner Care for Clinical Depression in Older Adults .. Nalin A. Singh, Theodora M. Stavrinos, Yvonne Scarbek, Garry Galambos, Cas Liber, and Maria A. Fiatarone Singh Effects of Maximal Isometric and Isokinetic Resistance Training on Strength and Functional Mobility in Older Adults T. Brock Symons, Anthony A. Vandervoort, Charles L. Rice, Tom J. Overend, and Greg D. Marsh Effects of Age and Fitness on Tolerance to Lower Body Negative Pressure ... . Juliane P. Hernandez, Amruta Karandikar, and Warren D. Franke Outcomes of Continuous Process Improvement of Nutritional Care Program Among Geriatric Units................... Thierry Pepersack Back Pain and Decline in Lower Extremity Physical Function Among Community-Dwelling Older Persons M. Carrington Reid, Christianna §. Williams, and Thomas M. Gill Geriatric Evaluation and Management Units in the Care of the Frail Elderly Cancer Patient Arati V. Rao, Frank Hsieh, John R. Feussner, and Harvey Jay Cohen Stature Prediction Equations for Elderly Hispanics in Latin American Countries by Sex and Ethnic Background Alberto Palloni and Abdelhani Guend Instructions to Authors VOLUME 60A NUMBER 7 Do Centenarians Die Healthy? An Autopsy Study Andrea M. Berzlanovich, Wolfg2 An Adequate Threshold for Body Mass Index to Detect Underweight Condition in Elderly Persons: The Italian Longitudinal Study on Aging (ILSA) Giuseppe Sergi, Egle Perissinotto, Claudia Pisent, Alessandra Buja, Stefania Maggi, Alessandra Coin, Francesco Grigoletto, and Giuliano Enzi, for the ILSA Working Group Abdominal Adiposity Assessed by Dual Energy X-Ray Absorptiometry Provides a Sex-Independent Predictor of Insulin Sensitivity in Older Adults Cathy C. Lee, Scott G. Glickman, Donald R. Dengel, Michael D. Brown, and Mark A. Supiano Is It Possible To Increase Weight and Maintain the Protein Status of Debilitated Elderly Residents of Nursing Homes? Yaakov Levinson, Tzvi Dwolatzky, Aviva Epstein, Bella Adler, and Leon Epstein Cross-Sectional Associations Between Trunk Muscle Composition, Back Pain, and Physical Function in the Health, Aging and Body Composition Study Gregory E. Hicks, Eleanor M. Simonsick, Tamara B. Harris, Anne B. Newman, Debra K. Weiner, Michael A. Nevitt, and Frances A. Tylavsky Hospitalization and Development of Dependence in Activities of Daily Living in a Cohort of Disabled Older Women: The Women’s Health and Aging Study I Cynthia M. Boyd, Qian-Li Xue, Jack M. Guralnik, and Linda P. Fried Magnitude and Patterns of Decline in Health and Function in 1 Year Affect Subsequent 5-Year Survival Subashan Perera, Stephanie Studenski, Julie M. Chandler, and Jack M. Guratnik Measuring Disability and Function in Older Women: Psychometric Properties of the Late-Life Function and Disability Instrument Edward McAuley, James F. Konopack, Robert W. Motl, Karl Rosengren, and Katherine S. Morris Age-Related Differences in Peak Joint Torques During the Support Phase of Single-Step Recovery From a Forward Fall Michael L. Madigan and Emily M. Lloyd The Effects of Preexisting Depression on Cerebrovascular Health Outcomes in Geriatric Continuing Care Mohan Krishnan, Benjamin T. Mast, Lisa J. Ficker, Larry Lawhorne, and Peter A. Lichtenberg Goiter in Adult Patients Aged 55 Years and Older: Etiology and Clinical Features in 634 Patients....................0..2005 Juan J. Diez Age-Dependent Differences in the Attentional Demands of Obstacle Negotiation Lesley A. Brown, Nicole C. McKenzie, and Jon B. Doan The Clock Drawing Test Is an Independent Predictor of Incident Use of 24-Hour Care in a Retirement Community Laurie L. Lavery, Scott M. Starenchak, William B. Flynn, Margaret A. Stoeff, Ruth Schaffner, and Anne B. Newman Black-White Disparities in Functional Decline in Older Persons: The Role of Cognitive Function mate Sandra Y. Moody-Ayers, Kala M. Mehta, Karla Lindquist, Laura Sands, and Kenneth E. Covinsky Intraduodenal Guar Attenuates the Fall in Blood Pressure Induced by Glucose in Healthy Older Adults sees Deirdre O' Donovan, Christine Feinle-Bisset, Chilton Chong, Alexander Cameron, Anne Tonkin, Judith Wishart, Michael Horowitz, and Karen Louise Jones Instructions to Authors 1610 VOLUME 60A AUGUST 2005 NUMBER 8 Guest Editorial. Neglect Assessment in Elderly Persons : Carmel Bitondo Dyer 000 Neglect Assessment in Urban Emergency Departments and ( ‘onlivenation bs an Es ec © tinical Tien S SROGRaTS mec STd : Terry Fulmer, Gregory Paveza, Carla VandeWeerd, Lisa Guadagno, Susan Fairchild, Robert Norman, lvo Abraham, and Marguarette Bolton-Blatt Weight Change, Weight Change Intention, and the Incidence of Mobility Limitation in Well-Functioning Community-Dwelling Older Adults Jung Sun Lee, Stephen B. Kritchevsky, Frances Tylavsky, Tamara Harris, Eleanor M. Simonsick, Susan M. Rubin, and Anne B. Newman for the Health ABC Study Serum C-Reactive Protein and Cognitive Function in Healthy Elderly Italian Community Dwellers Giovanni Ravaglia, Paola Forti, Fabiola Maioli, Nicoletta Brunetti, Mabel Martelli, Lucia Servadei, Luciana Bastagli, Marisa Bianchin, and Erminia Mariani Is There a Biomedical Explanation for Socioeconomic Differences in Incident Mobility Limitation? Annemarie Koster, Brenda W. J. H. Penninx, Hans Bosma, Gertrudis 1. J. M. Kempen, Tamara B. Harris, Anne B. Newman, Ronica N. Rooks, Susan M. Rubin, Eleanor M. Simonsick, Jacques T. M. van Eijk, and Stephen B. Kritchevsky Trends in Disability and Disability-Free Life Expectancy Among Elderly People in Spain: 1986-1999 ister seatee Ges Jon Sagardui-Villamor, Pilar Guallar-Castill6n, Margarita Garcia-Ferruelo, José Ramén Banegas, and Fernando Rodriguez-Artalejo Effect of Hospital in the Home Treatment on Physical and Cognitive Function: A Randomized Controlled Trial eats Gideon A. Caplan, Janis Coconis, and Jan Woods A Randomized, Crossover Trial of High-Carbohydrate Foods in Nursing Home Residents With Alzheimer’s Disease: Associations Among Intervention Response, Body Mass Index, and Behavioral and Cognitive Function Karen W. H. Young, Carol E. Greenwood, Robert van Reekum, ai a Malcolm A. Binns Frailty Index as a Measure of Biological Age in a Chinese Population ; William B. Goggins, ro Woo, Aprille Sham, and Suzanne C. Ho Identification of Risk Factors for 15-Year Mortality Among Community-Dwelling Older People Using Cox Regression and a Genetic Algorithm Rabiah Ahmad and Peter A. Bath An Empiric Approach to Level of Care Determinations: The Importance of Executive Measures Donald R. Royall, Laura K. Chiodo, and ithe J Polk Cognitive Function in Drinkers Compared to Abstainers in The New Mexico Elder Health Survey Robert D. Lindeman, Sharon J. Wayne, Richard N. Baumgartner, and Philip J. Garry Etiology and Clinical Course of Abdominal Pain in Senior Patients: A Prospective, Multicenter Study Lawrence M. Lewis, Gerald A. Banet, Michelle Blanda, Fredric M. Hustey, Stephen W. Meldon, and Lowell W Gerson Hair Loss Among Elderly Men: Etiology and Impact on Perceived Age Helle Rexbye, Inge Petersen, Maria lachina, Jakob Mortensen, Matt McGue, James W. Vaupel, and Kaare Christensen Letter to the Editor. Angle-Closure Glaucoma After Discontinuing Donepezil Hydrochloride (Aricept) Robert W. Enzenauer and Patrick J. Bowers Instructions to Authors VOLUME 60A SEPTEMBER 2005 NUMBER 9 Guest Editorial. Squaring the Circle: Adjuvant Chemotherapy for Older Women With Breast Cancer Lodovico Balducci 1135 Effectiveness of Adjuvant Chemotherapy for Node-Positive Operable Breast Cancer in Older Women Xianglin L. Du, Dennie V. Jones, and Dong Zhang Guest Editorial. Diabetes Is Common in Elderly Persons Graydon S. Meneilly Concealed Renal Failure and Adverse Drug Reactions in Older Patients With Type 2 Diabetes Mellitus aaa, Wertatenss arestaronr tard Andrea Corsonello, Claudio Pedone, Francesco Corica, Bruno Mazzei, Angelo Di lorio, Pierugo Carbonin, and Raffaele Antonelli Incalzi, for the Gruppo Italiano di Farmacovigilanza nell’ Anziano (GIFA) Diabetes Mellitus and Incidence of Lower Body Disability Among Older Mexican Americans ' Soham Al Snih, Michielle N. Fisher, Mukaila A. Raji, Kyriakos §. Markides, Glenn V. Ostir, and James §. Goodwin Diabetes Mellitus Is Associated With an Increased Risk of Falls in Elderly Residents of a Long-Term Care Facility Mathew S. Maurer, Joyce Burcham, and Huai Cheng Does Fear of Falling Influence Spatial and Temporal Gait Parameters in Elderly Persons Beyond Changes Associated With Normal Aging? Melissa E. Chamberlin, Brandy D. Fulwider, Sheryl L. Sanders, and John M. Medeiros Anemia Is Associated With Depression in Older Adults: Results From the InCHIANTI Study aaa away Graziano Onder, Brenda W. J. H. Penninx, Matteo Cesari, Stefania Bandinelli, Fulvio Lauretani, Benedetta Bartali, Anna Maria Gori, Marco Pahor, and Luigi Ferrucci State Variability in Indicators of Quality of Care in Nursing Facilities Nicholas G. Castle, Howard Degenholtz, and John Engberg Relationship Between Functional Loss Before Hospital Admission and Mortality in Elderly Persons With Medical Illness Soe oa aNe ee Sandra F. Simmons and John F. Schnelle Obesity and Mortality in Elderly Nursing Home Residents David C. Grabowski, Christine M. Campbell, and John E. Ellis Review Article. The Role of Homocysteine in Multisystem Age-Related Problems: A Systematic Review Hsu-Ko Kuo, Farzaneh A. Sorond, Jen-Hau Chen, Ardeshir Hashmi, William P. Milberg, and kel is A. Lipsitz Sex Differences in the Emergency Department Evaluation of Elderly Patients With Syncope Shamai A. Grossman, Nathan 1. Shapiro, Sara Van Epp, Rochelle Kohen, Ryan Arnold, Richard Moore, Lily Lee, Richard E. Wolfe and Lewis A. Lipsitz The Effect of Diabetes on Disability in Middle-Aged and Older Adults ; Linda A. Wray, Mary Beth Ofstedal, Kenneth M Seats and Caroline §. Blaum Postexercise Nutrient Intake Enhances Leg Protein Balance in Early Postmenopausal Women Lars Holm, Birgitte Esmarck, Charlotte Suetta, Keitaro Matsumoto, Tatsuya Doi, Masao Mizuno, Benjamin F. Miller, and Michael Kjae) Instructions to Authors VOLUME 60A OCTOBER 2005 NUMBER 10 Guest Editorial. Postprandial Hypotension: Simple Treatment But Difficulties With the Diagnosis 1268 High Prevalence of Postprandial and Orthostatic Hypotension Among Geriatric Patients Admitted to Dutch Hospitals Lilian C. M. Vloet, Ruth E. Pel-Little, Paul A. F. Jansen, and René W. M. M. Jansen 1271 Insulin Resistance and Muscle Strength in Older Persons Angela M. Abbatecola, Luigi Ferrucci, GianPaolo Ceda, Cosimo R. Russo, Fulvio Lauretani, Stefania Bandinelli, Michelangela Barbieri, Giorgio Valenti, and Giuseppe Paolisso 1278 Letter to the Editor. Insulin Resistance as an Adverse Effect of Leuprolide and Bicalutamide Treatment Miguel A. Paniagua and Irl B. Hirsch 1283 Review Article. A Critical Review of Literature Regarding the Effectiveness of Physical Therapy Management of Hip Fracture in Elderly Persons Emily Marie Toussant and Mohamed Kohia 1285 Physical Function and Its Response to Exercise: Associations With Cytokine Gene Variation in Older Adults With Knee Osteoarthritis Barbara J. Nicklas, Joe Mychaleckyj, Stephen Kritchevsky, Shana Palla, Leslie A. Lange, Ethan M. Lange, Stephen P. Messier, Don Bowden, and Marco Pahor Contribution of Genetic and Environmental Factors to Individual Differences in Maximal Walking Speed With and Without Second Task in Older Women Satu Pajala, Pertti Era, Markku Koskenvuo, Jaakko Kaprio, Markku Alén, Asko Tolvanen, Kristina Tiainen, and Taina Rantanen 1299 Gait Velocity as a Single Predictor of Adverse Events in Healthy Seniors Aged 75 Years and Older Manuel Montero-Odasso, Marcelo Schapira, Enrique R. Soriano, Miguel Varela, Roberto Kaplan, Luis A. Camera, and L. Marcelo Mayorga 1304 Trunk Repositioning Errors Are Increased in Balance-Impaired Older Adults Allon Goldberg, Manuel Enrique Hernandez, and Neil B. Alexander 1310 Chronic Resistance Exercise Training Improves Natural Killer Cell Activity in Older Women Brian K. McFarlin, Michael G. Flynn, Melody D. Phillips, Laura K. Stewart, and Kyle L. Timmerman 1315 The Apolipoprotein E e4 Polymorphism Is Strongly Associated With Poor Mobility Performance Test Results But Not Self-Reported Limitation in Older People David Melzer, M. G. Dik, Gerard J. van Kamp, Cees Jonker, and Dorly J. Deeg 1319 Acute Phase Response Detection and Quantitation at the Point of Care in Older Adults With Acute Bacterial Infections Ori Rogowski, Itzhak Shapira, Shlomo Berliner, Jack Serov, Pinhas Halpern, David Zeltser, Bernard Rudensky, and Tzvi Dwolatzky 1324 Cerebrovascular Diseases as Primary Hospital Discharge Diagnoses: National Trend (1970-2000) Among Older Adults Ali Ahmed, Jose Ness, George Howard, and Wilbert S. Aronow 1328 Long-Term Prediction of Mortality in Elderly Persons by Dobutamine Stress Echocardiography Elena Biagini, Abdou Elhendy, Arend F. L. Schinkel, Vittoria Rizzello, Jeroen J. Bax, Fabiola B. Sozzi, Miklos D. Kertai, Ron T. van Domburg, Boudewijn J. Krenning, Angelo Branzi, Claudio Rapezzi, Maarten L. Simoons, and Don Poldermans Association of Diastolic vsfunction and Outcomes in Ambulatory Older Adults With Chronic Heart Failure ................. Ali Ahmed The Future (History) of Socioeconomic Measurement and Implications for Improving Health Outcomes Among African Americans........ Elena M. Andresen and Douglas K. Miller Health Changes Among Swedish Oldest Old: Prevalence Rates From 1992 and 2002 Show Increasing Health Problems ................. Marti G. Parker, Kozma Ahacic, and Mats Thorslund Instructions to Authors VOLUME 60A NOVEMBER 2005 Changes in Biological Markers of Health: Older Americans in the 1990s oh ; Eileen M. Crimmins, Dawn Alley, Sandra L. Reynolds, Melanie Johnston, Arun Karlamangla, and Teresa Seeman 25(OH)D Serum Levels Decline With Age Earlier in Women Than in Men and Less Efficiently Prevent Compensatory Hyperparathyroidism in Older Adults Dario Maggio, Antonio Cherubini, Fulvio Lauretani, Roberto Cosimo Russo, Benedetta Bartali, Marco Pierandrei, Carmelinda Ruggiero, Maria Carmela Macchiarulo, Ruben Giorgino, Salvatore Minisola, and Luigi Ferrucci Trunk Muscle Composition as a Predictor of Reduced Functional Capacity in the Health, Aging and Body Composition Study: The Moderating Role of Back Pain oe acme Se Corer ‘ Gregory E. Hicks, Eleanor M. Simonsick, Tamara B. Harris, Anne B. Newman, Debra K. Weiner, Michael A. Nevitt, and Frances A. Tylavsky Effects of Progressive Resistance Training on Body Composition in Frail Older Adults: Results of a Randomized, Controlled Trial Ellen F. Binder, Kevin E. Yarasheski, Karen Steger-May, David R. Sinacore, Marybeth Brown, Kenneth B. Schechtman, and John O. Holloszy Exercise Accelerates Wound Healing Among Healthy Older Adults: A Preliminary Investigation Charles F. Emery, Janice K. Kiecolt-Glaser, Ronald Glaser, William B. Malarkey, and David J. Frid Angiotensin-Converting Enzyme Inhibition Intervention in Elderly Persons: Effects on Body Composition and Physical Performance Christy S. Carter, Graziano Onder, Stephen B. Kritchevsky, and Marco Pahor Lower Extremity Strength Plays Only a Small Role in Determining the Maximum Recoverable Lean Angle in Older Adults Mark D. Grabiner, Tammy M. Owings, and Michael J. Pavol Adverse Events Associated With Testosterone Replacement in Middle-Aged and Older Men: A Meta-Analysis of Randomized, Placebo-Controlled Olga M. Calof, Atam B. Singh, Martin L. Lee, Anne M. Kenny, Randall J. Urban, Joyce L. Tenover, and Shalender Bhasin Folate, But Not Homocysteine, Predicts the Risk of Fracture in Elderly Persons Giovanni Ravaglia, Paola Forti, Fabiola Maioli, Lucia Servadei, Mabel Martelli, Nicoletta Brunetti, Luciana Bastagli, Domenico Cucinotta, and Erminia Mariani The Variable Component of Lateral Body Sway During Walking in Young and Older Humans Roger C. Woledge, Deirdre B. Birtles, and Di J. Newham Strategies, Time, and Costs Associated With the Recruitment and Enrollment of Nursing Home Residents for a Micronutrient Supplementation Clinical Trial Paula M. Gismondi, Davidson H. Hamer, Lynette S. Leka, Gerard Dallal, Maria A. Fiatarone Singh, and Simin N. Meydani

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