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The Journals of Gerontology. Series A: Biological Sciences and Medical Sciences 2001: Vol 56A Table of Contents PDF

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Journal of Gerontology: BIOLOGICAL SCIENCES Contents of Volume 56A VOLUME 56A JANUARY 2001 NUMBER 1 Accuracy of Equations for Predicting Stature From Knee Height, and Assessment of Statural Loss in an Older Italian cian Riccardo Pini, Elisabetta Tonon, M. Chiara Cavallini, Francesca Bencini, Mauro Di Bari, Giulio Masotti, and Niccolo Marchionn Human Diploid Fibroblasts That Undergo a Senescent-like Differentiation Have Elevated Ceramide and Diacylglycerol arol J. Mi and Gretchen H. Steir An Age-Related Decline in Melatonin Secretion Is Not Altered by Food Restriction . . . ; ; Mary F. MacGi bbon, Ronald S. Walls and Arthur V. Everit Age-Associated Accumulation of the Apolipoprotein C-IIl Gene T-455C Polymorphism C Allele in a Russian Population Sergey V. Anisimov, Maria V. Volkova, Lilia V. Lenskaya, Vladimir K. Khavinson, Dina V. Solovieva, and Eugene Effects of Chronic Food Restriction and Exercise Training on the Recovery of Cardiac Function Following Ischemia Tom L. E William R. Driedzic, Melissa Gillis, Jacqueline Jacob, and Te Low- or High-Intensity Strength Training Partially Restores Impaired Quadriceps Force Accuracy and Steadiness in Aged Adults Tibor Hortobagyi, David Tunnel, Jill Moody, Stacey Beam, and Pau VOLUME 56A FEBRUARY 2001 NUMBER 2 Editorial 1. Faulkner B51 Interpretation, Design, and Analysis of Gene Array Expression Experiments Richard A. Miller Andrzej Galeck and Robert J. Shmookler-Reis — B52 Age, Fatigue, and Excitation-Contraction Coupling in Masseter Muscles of Rats aNd Margaret W. Norton, Walter Me and Roger J.M. McCarter B58 Age-Related Differences in Hippocampal Extracellular Fluid Glucose Concentration During Behavioral Testing and Following Systemic Glucose Administration Ewan C. McNay and Paul E. Gol Array-Based Expression Analysis of Meuse Lii ver Genes: Eff ect of Age and of the L ongevity Mutant Prop1# Igor Dozmoroy Andrzej Bartke, and Richard A Interleukin-6 Production Does Not Increase With Age Alison A. Beharka, Mohsen Meydani, Dayong Wu, Lynette S Ahou Meydani, and Simin Nikbin Meydan Female Sensitivity to Diet and Irradiation Treatments Underlies Sex—Mortality Differentials in the Mediterranean Fruit Fly James R. Carey Pablo Liedo, Hans-Georg Miiller, Jane-Ling Wang, Brad Love, Lawrence Harshman, and Linda Partr Instructions to Authors VOLUME 56A MARCH 2001 NUMBER 3 Acknowledgments BY Calorie Restriction and Skeletal Mass in Rhesus Monkeys (Macaca mulatta): Evidence for an Effect Mediated Through Changes in Body Size 4. Black, D.B. Allison, S.A. Shapses, E.M. Tilmont, A.M. Handy, D.K. Ingram, G.S. Roth, and M_A. Lar B Effects of Food Restriction on Systolic Mechanical Behavior of the Ventricular Pump in Middle-aged and Senescent Rats Kuo-Chu ¢ Ying-I Peng, Fong-Chu Lee, and Yung-Zu Tsen B Effects of Caloric Restriction on Skeletal Muscle Mitochondrial Proton Leak in Aging Rats .. Shirin B. Lal, Jon J. Ra mnSe Shadi Monemdjou, Richard Weindruch, and Mary-Ellen Har Dietary Restriction and Aging: Comparative Tests of Evolutionary Hypotheses .. . . ; Kevin L. Kirk Familial Excess Longevity in Utah Genealogies . y .... Richard A. Kerber, Elizabeth O’Brien, Ken R. Smith, and Richard M. ¢ Protective Efficacy of L-Carnitine on Acetyicholinesterase Activity in Aged Rat Brain . Packiasamy Juliet Arockia Rar and Chinnakannu Panneerselvan Instructions to Authors VOLUME 56A APRIL 2001 NUMBER 4 Senescent Expression of Genes Coding Collagens, Collagen-Degrading Metalloproteinases, and Tissue Inhibitors of nan in Rat Vocal Folds: Comparison With Skin and Lungs Hu Ding and Steven D. Gi Free Radical Defenses in the Liver and Kidney of Human Growth Hormone Transgenic Mice: Possible Mechanisms of Early Mortality : ; ; ‘ ee Steven J. Hauck and Andrzej Bartke Conditioning of Skeletal Muscles in Adult and Old Mice for Protection From Contraction-Induced Injury j Susan V. Brooks Julie A. Opiteck, and John A. Faulkner Telomere Erosion and Senescence i in Human Articular Cca rtilage Chondrocytes ..... James A. Martin and Joseph A. Buck Biomarkers of Aging: Prediction of Longevity by Using Age-Sensitive T-Cell Subset Determinations in a Middle- Aged, Genetically Heterogeneous Mouse Population ............. ' roiak ‘ : : . Richard A. M Instructions to Authors .. . . VOLUME 56A MAY 2001 NUMBER 5 Specific Force Deficit in Skeletal Muscles of Old Rats Is Partially Explained by the Existence of Denervated Muscle Fibers Melanie G. Urbanchek, Elisa B. Picken, Loree K. Kalliainen, and William M. Kuzon, Jr B191 Kinetics of Human Aging: I. Rates of Senescence Between Ages 30 and 70 Years in Healthy People Mary E. Sehl and F. Eugene Yates _B198 Longitudinal Muscle Strength Changes in Older Adults: Influence of Muscle Mass, Physical Activity, and Health ... Virginia A. Hughes, Walter R. Frontera, Michael Wood, William J. Evans, Gerard E. Dallal, Ronenn Roubenoff, and Maria A. Fiatarone Singh B209 Effect of Age on the Gastrointestinal-Associated Mucosal Immune Response of Humans . Alison A. Beharka, Sergio Paiva, Lynette S. Leka, Judy D. Ribaya-Mercado, Robert M. Russell, and Simin Nikbin Meydani —_B218 Skeletal Muscle Regeneration in Very Old Rats. . . : . Bruce M. Carlson, Eduard Ll Dedkov, Andrei B. Borisov, and John A. Faulkner B224 Instructions to Authors ; ; st danurercts ae Sige ae warctend evelaieaerrts B234 VOLUME 356A JUNE 2001 NUMBER6 B237 §.M. Roth, G.F. Martel, F.M. Ivey, J.T. Lemmer, B.L. Tracy, E.J. Metter, B.F. Hurley, and M.A. Rogers —_B240 Differential Influence of Physical Activity on Lumbar Spine and Femoral Neck Bone Mineral Density in the Elderly Population A. Vuillemin, F. Guillemin, P. Jouanny, G. Denis, and C. Jeandel B248 Motor Unit Properties of Nerve-Intact Extensor Digitorum Longus Muscle Grafts in Young and Old Rats Paul S. Cederna, Hirotaka Asato, Xiaoming Gu, Jack van der Meulen, William M. Kuzon, Jr., Bruce M. Carlson, and John A. Faulkner —B254 Aging Lowers Steady-State Antioxidant Enzyme and Stress Protein Expression in Primary Hepatocytes David M. Hall, Gerald L. Saitler, Carol A. Sattler, Hannah J. Zhang, Larry W. Oberley, Henry C. Pitot, and Kevin C. Kregel B259 Unexpected Effects of a Heterozygous Drmtl Null Mutation on Age-Dependent DNA Hypomethylation and Autoimmunity Raymond Yung, Donna Ray, Julie K. Eisenbraun, Chun Deng, John Attwood, Michael D. Eisenbraun, Kent Johnson, Richard A. Miller, Samir Hanash, and Bruce Richardson B268 Instructions to Authors B277 VOLUME 56A JULY 2001 NUMBER7 Heat Shock Protein Accumulation Is Upregulated in a Long-Lived Mutant of Caenorhabditis elegans .... . seccvescaecas Glenda A: Walker, Tiffany M. White, Gawain McColl, Nicole L. Jenkins, Sandra Babich, E. Peter M. Candido, Thomas E. Johnson, and Gordon J. Lithgow B281 Age-Related Changes in the Regulation of Autophagic Proteolysis in Rat Isolated Hepatocytes .. . Z Alessio Donati, Gabriella Cavallini, Cristina Paradiso, Simona Vittorini, Maria Pollera, Zina Gori, and Ettore Bergamini —B288 Predictors of Healthy Brain Aging .... Melissa Gonzales McNeal, Sepideh Zareparsi, Richard Camicioli, Alison Dame, Diane Howieson, Joseph Quinn, Melvyn Ball, Jeffrey Kaye, and Haydeh Payami — B294 Resistance Training in Patients With Peripheral Arterial Disease: Effects on Myosin Isoforms, Fiber Type Distribution, and Capillary Supply to Skeletal Muscle Michael R. M. McGuigan, Roger Bronks, Robert U. Newton, MatthewJ . Sharman, John C. Graham, David V. Cody, and William J. Kraemer Melatonin Increases Both Life Span and Tumor Incidence in Female CBA Mice ..... ...... Vladimir N. Anisimov, Natalia Y. Zavarzina, Mark A. Zabezhinski, Irina G. Popovich, Olga A. Zimina, Anastasia V. Shtylick, Alexander V. Arutjunyan, Tatiana I. Oparina, Valentina M. Prokopenko, AnatoliI . Mikhalski, and AnatoliI . Yashin Instructions to Authors VOLUME 56A AUGUST 2001 NUMBER8 Letters to the Editor eh afi cctna : 4 B327 Age-Specific Demographic Profiles of Longevity Mutants in Caenorhabditis elegans Show Segmental Effects ‘ ...- Thomas E. Johnson, Deqing Wu, Patricia Tedesco, Shale Dames, and James W. Vaupel Genes That Prolong Life: Relationships of Growth Hormone and Growth to Aging and Life Span ... . . .Andrzej Bartke, Karen Coschigano, John Kopchick, Varadaraj Chandrashekar, Julie Mattison, Beth Kinney, and Steven Hauck Gene Expression of Cyclooxygenase in the Aging Heart ; .... Jung Won Kim, Bong Sook Baek, Yun Kyung Kim, Jeremiah T. Herlihy, Yuji keno, Byung Pal Yu, and Hae Young Chung Differential Involvement of Conotoxin-Sensitive Mechanisms in Neurogenic Vasodilatation Responses: Effects of Age Zeinab Khalil, Merhi Merhi, and Bruce G. Livett Growth Hormone Increases Regional Coronary Blood Flow and Capillary Density in Aged Rats ....... .. Amir S. Khan, Colleen D. Lynch, DavidC . Sane, Mark C. Willingham, and William E. Sonntag Instructions to Authors VOLUME 56A SEPTEMBER 2001 NUMBER9 Age-Related Changes in the Autophagic Proteolysis of Rat Isolated Liver Cells: Effects of Antiaging Dietary Restrictions .. Alessio Donati, Gabriella Cavallini, Cristina Paradiso, Simona Vittorini, Maria Pollera, Zina Gori, and Ettore Bergamini Resistance Training Reduces Susceptibility to Eccentric Exercise-Induced Muscle Dysfunction in Older Women .......... L.L. Ploutz-Snyder, E.L. Giamis, M. Formikell, and A.E. Rosenbaum Food Restriction Enhances Endogenous and Corticotropin-Induced Plasma Elevations of Free but Not Total Corticosterone Throughout Life in Rats Eun-Soo Han, Ted R. Evans, Jian Hua Shu, Shuko Lee, and James F. Nelson B391 Relationship Between Muscle Strength and the Time Taken to Complete a Standardized Walk-Turn-Walk Test ... In Soon Kwon, Sandra Oldaker, Matthew Schrager, Laura A. Talbot, James L. Fozard, and E. Jeffrey Metter B398 Effect of Chronic Aminoguanidine Treatment on Age-Related Glycation, Glycoxidation, and Collagen Cross-linking in the Fischer 344 Rat . David R. Sell, James F. Nelson, and Vincent M. Monnier —B405 B412 VOLUME 56A OCTOBER 2001 NUMBER 10 Direct Selection for Paraquat Resistance in Drosophila Results in a Different Extended Longevity Phenotype a John Ve ttraino. Steven Buck, and Robert Arking B415 Age-Related Increase of Brain Cyclooxygenase Activity and Dietary Modulation of Oxidative Status ....... Bong Sook Baek, June Won Kim Ji Hyeon Lee, Hyun Joo Kwon, Nam Deuk Kim, Ho Sung Kang, Mi Ae Yoo, Byung Pal Yu, and Hae Young Chung B426 Have the Oldest Old Adults Ever Been Frail in the Past? A Hypothesis That Explains Modern Trends in Survival Anatoli i. Yashin, Svetlana V. Ukraintseva, Giovanna De Benedictis, Vladimir N. Anisimov, Alexander A. Butov, Konstantin Arbeev, Dmitri A. Jdanov, Serge l. Boiko, Alexander S. Begun, Maximiliano Bonafe, and Claudio Franceschi B432 The Interrelationship Among Muscle Mass, Strength, and the Ability to Perform Physical Tasks of Daily Living in Younger and Older Women ..Kathleen A. Landers, Gary R. Hunter, CarlaJ . Wetzstein, Marcas M. Bamman, and RolandL . Weinsier B443 Exercise Training Eliminates Age-Related Differences in Skeletal Muscle Insulin Receptor and IRS-1 Abundance in Rats Edward B. Arias, Luc E. Gosselin, and Gregory D. Cartee B449 Instructions to Authors . . . B456 VOLUME 56A NOVEMBER 2001 NUMBER ll Age-Related Changes in Protein Oxidation and Proteolysis in Mammalian Cells . Tilman Grune, Reshma Shringarpure Nicolle Sitte, and Kelvin Davies B459 Exceptional Cellular Resistance to Oxidative Damage in Long-Lived Birds Requires Active Gene Expression .. . Charles E. Ogburn Kristen Carlberg, Mary Ann Ottinger, Donna J. Holmes, George M. Martin, and Steven N. Austad B468 Apoptosis and Aging: Role of the Mitochondria Michael Pollack and Christiaan Leeuwenburgh B475 Age-Associated Increase of 8-Hydroxydeoxyguanosine in Human Colorectal Tissue DNA .. Yosuke Tsurudome, Takeshi Hirano Keiji Hirata, Aiichiro Higure, Naoki Nagata, Ken Takahashi, Hideaki Itoh, and Hiroshi Kasai 483 Effect of Aging and Obesity on Insulin Responsiveness and Glut-4 Glucose Transporter Content in Skeletal Muscie of Fischer 344 x Brown Norway Rats .. ...... Lisa M. Larkin, Thomas H. Reynolds, Mark A. Supiano, Barbara B. Kahn, and Jeffrey B. Halter BA86 Instructions to Authors B493 VOLUME 56A DECEMBER 2001 NUMBER 12 Familial Aggregation of 7-Year Changes in Musculoskeletal Fitness ... . ...........- Peter T. Katzmarzyk, Norman Gledhill, Louis Pérusse, and Claude Bouchard Mitochondrial Enzyme Defects in Normal and Low-Frequency-Stimulated Muscles of Young and Aging Rats ....... . Dejan Skorjan Georg Diinstl, and Dirk Pette Fiber-Type Transitions and Satellite Cell Activation in Low-Frequency-Stimulated Muscles of Young and Aging Rats .. Charles T. Putman Karim R. Sultan, Thomas Wassmer, Jeremy A. Bamford, Dejan Skorjanc, and Dirk Pette Reduced Basal Leveis and Enhanced LPS Response of IL-6 mRNA in Aged Mice ...... Kaizhi Sharman, Edward Sharman, {rezoo Campbell and Stephen C. Bondy Old Adults Exhibit Greater Motor Output Variability Than Young Adults Only During Rapid Discrete Isometric Contractions Evangelos A. Christou and Les G. Carlton Journal of Gerontology: MEDICAL SCIENCES Contents of Volume 56A VOLUME 56A JANUARY 2001 NUMBER 1 Editorial: The State of the Journal : JohnE . Morley M2 Editorial: Epidemiology of Urinary Incontinence Belanais Ananias C. Diokno M3 Diabetes in Elderly Adults aie Graydon S. Meneilly and Daniel Tessier M5 Prevalence Rate of Urinary Incontinence in Community-Dwelling Elderly Individuals: The Veneto Study Stefania Maggi Nadia Minicuci, Jean Langlois, Mara Pavan, Giuliano Enzi, and Gaetano Crepaldi M14 New-Onset Incontinence and Markers of Frailty: Data From the Hispanic Established Populations for Epidemiologic Studies of the Elderly Toni P. Miles, Raymond F. Palmer, David V. Espino, Charles P. Mouton, Michael J. Lichtenstein, and Kyriakos S. Markides M19 Age 85+ Years Accelerates Large-Fiber Peripheral Nerve Dysfunction and Diabetes Contributes Even in the Oldest-Old: The Women’s Health and Aging Study . Helaine E. Resnick, Aaron I. Vinik, Harley K. Heimovitz, Frederick L. Brancati, and Jack M. Guralnik M25 Reliability Assessment of the Bladder Diary for Urinary Incontinence in Older Women .. Julie L. Locher, Patricia §. Goode, David L. Roth, Rebecca L. Worrell, and Kathryn L. Burgio M32 The Effects of Antidepressants on Obstructed and Unobstructed Gait in Healthy Elderly People ..... . Louis F. Draganich, James Zacny, Jerome Klafta, and Theodore Karrison Elderly Subjects’ Ability to Recover Balance With a Single Backward Step Associates With Body Configuration at Step Contact Elizabeth T. Hsiao and Stephen N. Robinovitch The Correlation of Cytokine Levels With Body Weight After Megestrol Acetate Treatment in Geriatric Patients ........... Shing-shing Yeh, Suh-yuh Wu, Daniel M. Levine, Thomas S. Parker, Jeffery S. Olson, Michael R. Stevens, and Michael W. Schuster Self-reported and Clinical Oral Health in Users of VA Health Care .... ae ae .. Judith A. Jones, Nancy R. Kressin, Avron Spiro II], Carolyn W. Randall, Donald R. Miller, Catherine Haves, Lewis Kazis, and RaulI . Garcia Instructions to Authors VOLUME 56A FEBRUARY 2001 NUMBER Guest Editorial: Genetic and Phenotypic Markers Among Centenacians Thomas Perls M67 Guest Editorial: What Do the Serum Proteins Tell Us About Our Elderly Patients? .................. er Dennis H. Sullivan M7\ Longevity and the c2 Allele of Apolipoprotein E: The Finnish Centenarians Study .... . . ; ... Giovanni B. Frisoni, Jukka Louhija Cristina Geroldi, and Marco Trabucchi M75 Serum Insulin-like Growth Factor-1 in Centenarians: Implications of IGF-1 as a Rapid Turnover Protein . - . Yasumichi Arai, Nobuyoshi Hirose, Ken Yamamura, Ken-ichirou Shimizu, Michiyo Takayama Yoshinort Ebihara, and Yasunori Osono| M79 Searching for Human Longevity Genes: The Future History of Gerontology in the Post-genomic Era ..- Nir Barzilai and Alan R. Shuldiner M83 Heart Failure in the 2ist Century: A Cardiogeriatric Syndrome ; : Michael W. Rich M88 Effects of Housing Relocation on Immunocompetence and Psychosocial Functioning in Older Adults ee ‘ Susan K. Lutgendorf, Toni Tripp Reimer, John H. Harvey, Glenn Marks, Sue-Young Hong, Stephen | Hillis, and David M. Lubaroff M97 rhe Effects of a Collaborative Model of Primary Care on the Mortality and Hospital Use of Community-Dwelling Older Adults Cheryl Schraeder, Paul Shelton, and Mark Sager M106 Sildenafil Citrate (VIAGRA®) Improves Erectile Function in Elderly Patients With Erectile Dysfunction: A Subgroup Analysis Gorm Wagner, Francesco Montorsi, Stephen Auerbach, and Michael Collins M113 Infections in Nursing Homes: Assessing Quality of Care Gregg Warshaw, Shahla Mehdizadeh, and Robert A. Applebaum M120 Aging-Related Growth Hormone (GH) Decrease Is a Selective Hypothalamic GH-Releasing Hormone Pulse Amplitude Mediated Phenomenon Mary Russell-Aulet, Eleni V. Dimaraki, Craig A. Jaffe, Roberta DeMott-Friberg, and Ariel L. Barkan M124 Instructions to Authors M130 VOLUME 56A MARCH 2001 NUMBER3 Acknowledgments . ; M133 Guest Editorial: Pinning Down Frailty Muriel Gillick M134 Guest Editorial: The Use of COX-2-Specific Inhibitors: Is It All Hype. or Is It Evidence Based? Mavarslonets Akgun Ince M136 Treatment of Older Persons With Hypercholesterolemia With and Without Cardiovascular Disease .. . : ...... Wilbert S. Aronow M138 Frailty in Older Adults: Evidence fora Phenotype : ; oe Li nda P. Fried, Catherine M. Tangen, Jeremy Walston, Anne B. Newman, Calvin Hirsch, John Gottdiener, Teresa Se eman, Russell Tracy, Willem J. Kop, Gregory Burke, ind Mary Ann McBurnie for the Cardiovascular Health Study Collaborative Research Group M146 Associationosf Subclinical Cardiovascular Disease With Frailty Ann B. Newman, John S. Gottdiener, Mary Ann McBurnie, Calvin H. Hirsch, Willem J. Kop, Russell Tracy, Jeremy D. Walston, and Linda P. Fried for the Cardiovascular Health Study Research Group M158 Functional Status and Health-Related Quality of Life of Elderly Osteoarthritic Patients Treated With Celecoxib ............... . Jeffrey Lisse, Luis Espinoza, Sean Z. Zhao, Seema D. Dedhiya, and Jane T. Osterhaus M167 informants’ Knowledge of Reproductive History and Estrogen Replacement Rebecca A. Watkins, Robin Guariglia, Jeffrey A. Kaye, and Jeri §. Janowsky M176 Age-Associated Differences in Responses to Noxious Stimuli . Robert R . Edwards and Roger B. Fillingim M180 Effects of Policosanol in Older Patients With Type Il Hypercholesterolemia and High c oronary Risk Gladys Castano, Rosa Mas, J.C. Fernandez, J. Ilinait, Lilia Fernandez, and Estrella Alvarez M186 M800 VOLUME 56A MARCH 2001 SPECIAL ISSUE I Human Implications of Caloric Restriction’s Effects on Aging in Laboratory Animals: An Overview of Opportunities for Research Evan C. Hadley, Chhanda Dutta, Judith Finkelstein, Tamara B. Harris, Mark A. Lane, George S. Roth, Sherry S. Sherman and Pamela E. Starke-Reed 5 Epidemiologic Data on the Relationships of Caloric Intake, Energy Balance, and Weight Gain Over the Life Span With Longevity and Morbidity I-Min Lee, Steven N. Blair, David B. Allison, Aaron R. Folsom, Tamara B. Harris, JoAnn E. Manson, and Rena R. Wing 7 Caloric Restriction Mimetics: Metabolic Interventions ............ Richard Weindruch, Kevin P. Keenan, John M. Carney, Gabriel Fernandes Ritchie J. Feuers, Robert A. Floyd, Jeffrey B. Halter, Jon J. Ramsey, Arlan Richardson, George S. Roth, and Stephen R. Spindler 20 Neuroendocrire and Pharmacological Manipulations to Assess How Caloric Restriction Increases Life Span Charles V. Mobbs George A. Bray, Richard L. Atkinson, Andrzej Bartke, Caleb E. Finch, Eleftheria Maratos-Flier, Jacqueline N. Crawley, and James F. Nelson 34 Caloric Restriction Mimetics: Physical Activity and Body Composition Changes .. . Eric T. Poehlman, Angelo Turturro, Noni Bodkin William Cefalu, Steve Heymsfield, John Holloszy, and Joseph Kemnitz 45 Genetic Variability in Responses to Caloric Restriction in Animals and in Regulation of Metabolism and Obesity in Humans David B. Allison, Richard A. Miller, Stephen N. Austad, Claude Bouchard, Rudolph Leibel, Simon Klebanov, Thomas Johnson and David E. Harrison na Physiologic Effects of Lowering Caloric Intake in Nonhuman Primates and Nonobese Humans Susan B. Roberts, Xavier Pi-Sunyer Lewis Kuller, Mark A. Lane, Peter Ellison, Jerilynn C. Prior, and Susan Shapses 66 Contributing Authors .......... vib eebine nue ee hearer ‘ $e : ; ; ; 76 VOLUME 56A APRIL 2001 NUMBER 4 Guest Editorial: Bitter-Sweet Memories: Truth and Fiction .......................-....-.... sue Margaret-Mary G. Wilson M196 Flavor Enhancement of Food Improves Dietary Intake and Nutritional Status of E Iderly Nursing Home Residents . Marie-Frangoise A.M. Mathey, Els Siebelink, Cees de Graaf, and Wya A. Van Staveren M200 Metabolic, Psychological, and Health Correlates of Dietary Restraint in Healthy Postmenopausal Women. .... . . Gaston P. Bathalon Nicholas P. Hays, Simin N. Meydani, Bess Dawson-Hughes, Ernst J. Schaefer, Ruth Lipman, Miriam Ne lson, Andrew S. Greenberg and Susan B. Roberts M206 Nutritional Parameters, Body Composition, and Progression of Disability in Older Disabled Residents Living in Nursing Homes Giovanni Zuliani, Franco Romagnoni, Stefano Volpato, Lucia Soattin, Vincenzo Leoci, Maria Cristina Bollini, Mauro Buttarello aii Daniela Lotto, and Renato Fellin (212 eg eer eee ee eee eae ee ..... Anne-Sophie Rigaud and Bernard Forette M217 Evaluating the Effectiveness ofa Home- Based Fall Risk Reduction Program for Rural co mmunity-Dwelling Older Adults Shawna M. Yates and Tim A. Dunnagan M226 Stress in Caregivers of Hospitalized Oldest-Old Patients wr aa Siam, Re ; , ; Norman A. Desbiens, Nancy Mueller-Rizner, Beth Virnig, and Joanne Lynn for the HELP Investigators M2 High Plasma Insulin and Lipids Profile in Older Individuals: The Italian Longitudinal Study on Aging .. .. Stefania Maggi, Nadia Minicuci Tamara Harris, Luciano Motta, Marzia Baldereschi, Antonio Di Carlo, Domenico Inzitari, and Gaetano Crepaidi for the ILSA Group M236 Lower Body Function and Mortality in Mexican American Elderly People . ..... Kyriakos S. Markides, Sandra A. Black, Glenn V. Ostir Ronald J. Angel, Jack M. Guralnik, and Michael Lichtenstein M243 Validity of the Multi-Directional Reach Test: A Practical Measure for Limits of Stability in Older Adults .... . Roberta A. Newton M248 History and Mobility Exam Index to Identify Community-Dwelling Elderly Persons at Risk of Falling Kenneth E. Covinsky, Eva Kahana, Boaz Kahana, Kyle Kercher, John G. Schumacher, and Amy C. Justice M253 Instrutco Atutihoorsn s .............. VT NEREAA RONae ao abe ele ower xekons ives M260 VOLUME 56A MAY 2001 NUMBER 5 Editorial: Andropause: Is It Time for the Geriatrician to Treat It? ................... John E. Morley M263 Effects of Transdermal Testosterone on Bone and Muscle in Older Men With Low Bioavailable Testesterene Levels Anne M. Kenr Karen M. Prestwood, Cynthia A. Gruman, Kristina M. Marcello, and Lawrence G. Raisz. M266 Orthostatic Hypotension in Elderly Persons During Passive Standing: A Comparison With Young Persons . Takavasu Kawaguchi Osamu Uyama, Miwako Konishi, Tadahiro Nishivama, and Takeo lida M273 Effect of Intense Strength Training on Standing Balance, Walking Speed, and Sit-to-Stand Performance in Older Adults Jeffrey Schlicht David N. Camaione, and Steven V. Owen M28 Laparoscopic Nephrectomy in Young-Old, Old-Old, and Oldest-Old Adults . sae Paolo Fornara, Christian Doehi Robert Frese, and Dieter Jocham M287 Clinical Characteristics and Six-Month Outcomes of Nursing Home Residents With Low Activities of Daily Living ee Amna Buttar, Caroline Blaum, and Brant Fries M292 Aerobic Ex ercise and Resting Blood Pressure in Older Adults: A Meta- analytic Review of Randomized Controlled Trials George A. Kelley and Kristi Sharpe Kelley M298 Near 10- Ye ar and Longer Periods Modulate Circadians: intersecting Anti-- aging and Chronoastrobiological Research. Franz Halberg Germaine Cornélissen, Yoshihiko Watanabe, Kuniaki Otsuka, Bohumil Fiser, Jarmila Siegelova, Vlasta Mazankova, Cristina Maggion Robert B. Sothern, George S. Katinas, Elena V. Syutkina, Naoto Burioka, and Othild Schwartzkopff M304 ee ee eee ee or band M325 VOLUME 56A JUNE 2001 NUMBER 6 Issues and Dilemmas in the Prevention and Treatment of Pressure Ulcers: A Review ; David R. Thomas M328 Coping With Population Aging in the Old Continent—The Need for European Academic Geriatrics J.-P. Michel and G. Gold M34 Bioelectrical Impedance Analysis Estimation of Water Compartments in Elderly Diseased Patients: The Source Study Patrick Ritz for the Source Sudy M344 M80i Chronic Cellular Dehydration in the Aged Patient see ee ..e+ese+. Patrick Ritz and the Investigators of the Source Study and of the Human Nutrition Research Centre-Auvergne M349 Endogenous Anticholinergic Substances May Exist During Acute Illness in Elderly Medical Patients . Jonathan M. Flacker and Jeanne Y. Wei M353 Bright Light Treatment Decreases Depression in Institutionalized Older Adults: A Placebo-Controlled Crossover Study ....... /sabel C. Sumaya, Beth M. Rienzi, Jess F. Deegan Il, and Donald E. Moss M356 Reasons Prompting Digitalis Therapy in the Acute Care Hospital. ......... Raffaele Antonelli Incalzi, Claudio Pedone, Marco Pahor, uciana Carosella, Roberto Bernabei, PierUgo Carbonin, and the GIFA Investigators M361 Screening for Undernutrition in Geriatric Practice: Developing the Short-Form Mini-Nutritional Assessment (MNA-SF) Laurence Z. Rubenstein, Judith O. Harker, Antoni Salva, Yves Guigoz, and Bruno Vellas M366 The Recommended Dietary Allowance for Protein May Not Be Adequate for Older People to Maintain Skeletal Muscle . Wayne W. Campbell, Todd A. Trappe, Robert R. Wolfe, and William J. Evans M373 Differences in the Neuromuscular Capacity and Lean Muscle Tissuei in Old and Older Community-Dwelling Adults Ecosse L. Lamoureux, W.A. Sparrow, Aron Murphy, and Robert U. Newton M381 Effect of Age on Ocular Microtremor Activity Ciaran Bolger, Stana Bojanic, Noirin F. Sheahan, Davis Coakley, and James F. Malone M386 Efficacy of Influenza Vaccine in Elderly Persons in Welfare Nursing Homes: Reduction in Risks of Mortality and Morbidity During an Influenza 4 (H3N2) Epidemic Yasuhiro Deguchi and Kumi Nishimura M391 VOLUME 56A JULY 2001 NUMBER 7 Guest Editorial: “Who's Taking Your 5th Vital Sign?” .. Joseph H. Flaherty M397 Impact of Pain on Disability Among Older Mexican Americans ..... Soham Al Snih, Kyriakos S. Markides, Laura Ray, and James S. Goodwin M400 Accuracy and Bias of Licensed Practical Nurse and Nursing Assistant Ratings of Nursing Home Residents’ Pain . Veronica F. Engle, MarshallJ . Graney, and Anna Chan M405 Have We Oversold the Benefit of Late-Life Exercise? Julie J. Keysor and Alan M. Jette M412 Atypical Presentation of Scabies Among Nursing Home Residents ....... Margaret-Mary G. Wilson, Carolyn D. Philpott, and Wayne A. Breer M424 Mechanisms Leading to a Fall From an Induced Trip in Healthy Older Adults Michael J. Pavol, Tammy M. Owings, Kevin T. Foley and Mark D. Grabiner M428 Trunk Sway Measures of Postural Stability During Clinical Balance Tests: Effects of Age ......... . J. Gill, J. H. J. Allum, M. G. Carpenter, VM. Held-Ziolkowska, A. L. Adkin, F. Honegger, and K. Pierchala| M438 Instrumental Activities of Daily Living as a Potential Marker of Frailty: A Study of 7364 Community-Dwelling Elderly Women (the EPIDOS Study) Fati Nourhashémi, Sandrine Andrieu, Sophie Gillette-Guyonnet, Bruno Vellas, Jean Louis Albaréde, and Héléne Grandjean Impaired Balance and Higher Prevalence of Falls in Subjects With Intermittent Claudication .. . Andrew W. Gardner and Polly S. Montgomery Instructions to Authors VOLUME 56A AUGUST 2001 NUMBER 8 Letter to the Editor é ; rh ccoiatats alssorere eee ere ener mene : edu aan M463 Physical Activity Outcomes of CHAMPS II: A Physical Activity Promotion Program for Older Adults ‘ Anita L. Stewart, Carol J. Verboncoeur, Barbara Y. McLellan, Dawn E. Gillis, Stephanie Rush, Kris M. Mills, Abby C. King, Philip Ritter, Byron W. Brown, Jr., and Walter M. Bortz Il M465 Chronic Rheumatologic Symptoms in a Tri-Ethnic Sample of Men and Women Aged 75 and Older. . Shiva Satish, Luis G. Postigo, Laura A. Ray, and James §. Goodwin M47 Evidence for a Shift in the Th-1 to Th-2 Cytokine Response Associated With Chronic Stress and Aging ..... Ronald Glaser Robert C. MacCallum, Bryon F. Laskowski, William B. Malarkey, John F. She vide in, and Janice K. Kiecolt-Glaser M477 Anthropometric Changes Over 5 Years in Elderly Canadians by Age, Gender, and Cognitive Status : ... Bryna Shatenstein, Marie- lea ne Kergoat, and Sylvie Nadon M483 he Interacting Effects of Cognitive Demand and Recovery of Postural Stability in Balance-Impaired Elderly Persons . Sandra G. Brauer, Marjorie Woollacott, and Anne Shumway-Cook M489 The Efficacy of Exercise as a Long-term Antidepressant in Elderly Subjects: A Randomized, Controlled Trial 3 Nalin A. Singh, Karen M. Clements, and Maria A. Fiatarone Singh M497 The Association of Depression and Mortality in Elderly Persons: A Case for Multiple, Independent Pathways ... Dan G. Blazer, Celia F. Hybels, and Carl F. Pieper M505 Nonsteroidal Anti-Inflammatory Therapy After Eccentric Exercise in Healthy Older Individuals Angela Christine Baldwin, Scot Walter Stevenson, and Gary Alton Dudley M510 Survey of Primary Care Physicians’ Approach to Gastroesophageal Reflux Disease in Elderly Patients. .. . . . ...C. Mel Wilcox, Gustavo Heudebert, Joshua Klapow, Ric hard She wehuk, and Linda Casebeer M514 Skilled Finger Movement Exercise Improves Hand Function Vinoth K. Ranganathan, Vlodek Siemionow, Vinod Sahgal, Jing Z. Liu, and Guang H. Yue Instructions to Authors VOLUME 56A SEPTEMBER 2001 NUMBER 9 Guest Editorial: Nonage Versus Age ...... Walter M. Bortz [1 M527 Milestone or Genomania? The Relevance of the Human Genome Project to Biological Aging and the Age-Related Diseases Herman T. Blumenthal M529 Effects of Functional Ability and Training on Chair-Rise Biomechanics in Older Adults 5 Neil B. Alexander, M. Melissa Gross, Jodi L. Medell, and Mark R. Hofmeyer M538 Prevalance of Functional Blindness, Visual Impairment, and Related Functional Deficits Among Elderly Mexican Americans Anthony R. DiNuzzo, SandraA . Black, MichaelJ . Lichtenstein, and Kyriakos 8. Markides M548 M802 Construct Validation and Test—Retest Reliability of the Seniors in the Community: Risk Evaluation for Eating and Nutrition Questionnaire Heather H. Keller, Jacquelyn D. McKenzie, and Richard E. Goy The Minnesota Senior Health Options Program: An E arty Eff ort att Integrating Care for the Dually Eligible . . Robert L. Kane, Andrea Weiner, Patricia Homyak, and Boris Bershadsky Predictor Index of Mortality in Dementia Patients Upon Entry Into Long-term Care ........ Michelle C. Carlson, Jason Brandt, Cynthia Steele, Alva Baker, Yaakov Stern, and Constantine G. Lyketsos Evaluating Eye-Body Coordination During Unrestrained Functional Activity in Older Persons cas . Richard P. Di Fabio, Saurav Paul Alongkot Emasithi, and John F. Greany Effect of Aging and Diabetes on the Enteroinsular Axis ; Judit Korosi, Christopher H.S. McIntosh, Raymond A. Pederson Hans-Ulrich Demuth, JoelF . Habener, Ronald Gingerich, Josephine M. Egan, Dariush Elahi, and Graydon S. Meneilly M575 Comparison of Elderly Nonfallers and Fallers on Performance Measures of Functional Reach, Sensory Organization, and Limits of Stability Harvey W. Wallmann M580 How Quickly Can Healthy Adults Move Their Hands to» Intercept ann Approaching Object? , Age and Gender Effects Kurt M. DeGoede, James A. Ashton-Miller, Jimmy M. Liao, and Neil B. Alexander M584 Lateral Stability During Forward-Induced Stepping for Dynamic Balance Recovery in Young and Older Adults Mark W. Rogers Lois D. Hedman, Marjorie E. Johnson, Thomas D. Cain, and Timothy A. Hanke M589 Instructions to Authors . M595 VOLUME 56A OCTOBER 2001 NUMBER 10 Guest Editorial: The Critical Link Between Health-Related Quality of Life and Age-Related Changes in Physical Activity and Nutrition ais ae Wiese Scat wakes ; ‘ 7 Selodte cases : ; David R. Thomas M599 The Future History of Home Care and Physician House Calls in the United States .... .. Bruce Leff and John R. Burton M603 Walking Difficulty, Walking Speed, and Age as Predictors of Self-Rated Health: The Women’s Health and Aging Study Marja Jythé Jack M. Guratnik, Jennifer Balfour, and Linda P. Fried M609 Relationship Between Physiological Loss, Performance Decrement, and Age in Master Athletes . . Robert A. Wiswell, Steven A. Hawkins S. Victoria Jaque, Dan Hyslop, Nora Constantino, Kyle Tarpenning, Taylor Marcell, and E. Todd Schroeder M618 Choice Stepping Reaction Time: A Composite Measure of Falis Risk in Older People ar .... Stephen R. Lord and Richard C. Fitzpatrick M627 A Population-Based Study on Brain Atrophy and Motor Performance in Elderly Women .... Xinxin Guo, Bertil Steen, Michael Matousek Lars Arne Andreasson, Lena Larsson, Sigurdur Palsson, Valter Sundh, and Ingmar Skoog M633 The Hierarchy of Functional Loss Associated With Cognitive Decline in Older Persons Vesna Njegovan, Malcolm Man-Son-Hing Susan L. Mitchell, and Frank J. Molnar M638 Measuring Higher Level Physical Function in Well-Functioning Older Adults: Expanding Familiar Approaches in the Health ABC Study Sarwiacers Eleanor M. Simonsick, Anne B. Newman, Michael C. Nevitt, Stephen B. Kritchevsky, Luigi Ferrucci, Jack M. Guralnik and Tamara Harris for the Health ABC Study Group M644 Use of Alternative Therapies in Older Outpatients in the United States and Japan: Prevalence, Reporting Patterns, and Perceived Effectiveness Joseph H. Flaherty, Ryutaro Takahashi, JoAnne Teoh, Jeung-im Kim, Shazia Habib, Mio Ito, and Satoru Matsushita) M650 Meal Delivery Practices Do Not Meet Needs of Alzheimer Patients With Increased Cognitive and Behavioral Difficulties in a Long-term MS IMME 05. oiss. coke anee ss ; ; Pesincuears Karen W.H. Young, Malcolm A. Binns, and Carol E. Greenwood M656 Letters to the Editor. FiO RCA Wasa Rawal ; M662 Instructions to Authors . . ee aks ; M664 VOLUME 56A OCTOBER 2001 SPECIAL ISSUE Il Introduction .. 3s , Adam Drewnowski and William J. Evans, Co-Editor Physical Activity and Parameters of Aging: A Physiological Perspective : Klaas R. Westerterp and Erwin P. Meije Physical Activity in Aging: Changes in Patterns and Their Relationship to Health and Function Loretta DiPietro Physical Activity and Quality of Life in Older Adults. ; : 3 . W. Jack Rejeski and Shannon L. Mihalko Interventions to Promote Physical Activity by Older Adults. . . . . Bas ees os ; Abby C. King Nutrition and Health Promotion in Older Adults. . seamed ; = Ronni Chernoff Nutrition and Quality of Life in Older Adults... .... aie . Eleni Amarantos, Andrea Martinez, and Johanna Dwy Dietary Intake, Dietary Patterns, and Changes With Age: AnE pidemiological Perspective Patricia Wakimoto and Gladys Block Decreased Food Intake With Aging ‘ pane awe cds John E. Morley Nutrition, Physical Activity, and Quality of Lifei i n Older Adults: Summary ‘ Adam Drewnowski and William J. Evans, Co-Efdei tors VOLUME 56A NOVEMBER 2001 NUMBER Ii Gaze Into the Long-term Care Crystal Ball: The Veterans Health Administration and Aging -. . Frederick L. Malphurs and Joseph A. Striano M666 In Memoriam: William Reynish te - byt we daw eateek meena Bruno Vellas and Alan J. Sinclair M674 Nutritional Factors and Alzheimer’s Disease. aicka iad : , William Reynish, Sandrine Andrieu, Fati Nourhashemi, and Bruno Vellas M675 Errata ‘ M680 Glucagon-like Peptide-1 (7-37) Augments Insulin-Mediated Glucose Uptake in Elderly Patients With Diabetes Graydon S. Meneil!s Christopher H.S. McIntosh, Raymond A. Pederson, Joel F. Habener, Ronald Gingerich, Josephine M. Egan, and Dariush Elahi M68} Do the Risks and Consequences of Hospitalized Fall Injuries Among Older Adults in California Vary by Type of Fall? Arthur A. Ellis and Roger B. Trent M686 Factors Associated With Long-term Institutionalization of Older People With Dementia: Data From the Canadian Study of Health and Aging . Réjean Hébert, Marie-France Dubois, Christina Wolfson, Larry Chambers, and Carole Cohen M693 Shift in Diurnal Feeding Patterns in Nursing Home Residents With Alzheimer’s Disease . .Karen W.H. Young and Carol E. Greenwood M700 Reduced Employment in Caregivers of Frail Elders: Impact of Ethnicity, Patient Clinical Characteristics, and Caregiver Characteristics Kenneth E. Covinsky, Catherine Eng, Li-Yung Lui, Laura P. Sands, Ashwini R. Sehgal, Louise C. Walter, Darryl Wieland G. Paul Eleazer, and Kristine Yaffe ©M 707 M803 The Use of Herbal Medicine by Older Mexican Americans. .......... JoseA . Loera, Sandra A. Black, Kyriakos S. Markides, David V. Espino, and James S. Goodwin Age and Gender Effects on Cardiomyocyte Apoptosis in the Normal Human Heart. . ......-Ziad Mallat, Paul Fornes, Rémi Costagliola, Bruno Esposito, Joél Belmin, Deminique Lecomte, and Alain Tedgui Protein Requirement of Elderly Women: Nitrogen Balance Responses to Three Levels of Protein Intake .... ...... M. Hannah Morse, Mark D. Haub, William J. Bv ans, and Wayne W. Campbell Mandibular and Palatal Tori, Bone Mineral Density, and Salivary Cortisol in Community-Dwelling Elderly Men and Women Jadwiga Hiertstedt, Edith A. Burns, Raymond Fleming, Hershel Raff, Inge Rudman, Edmund H. Duthie, and Charles R. Wilson Letters to the Editor VOLUME 56A DECEMBER 2001 NUMBER 12 Editorial: Postprandial Hypotension—The Ultimate Big Mac Attack ........ ... John E. Morley M741 The Influence of Low-, Normal-, and High-Carbohydrate Meals on Blood Pressure in Elderly Patients With Postprandial Hypotension . Lilian C.M. Vloet, D. Jannet Mehagnoul-Schipper, Willibrord H.L. Hoefnagels, and René W.M.M. Jansen M744 Effect of Levodopa on Orthostatic and Postprandial Hypotension in Elderly Parkinsonian Patients ........... D. Jannet Mehagnoul-Schipper, Rudolf H. Boerman, Willibrord H.L. Hoefnagels, and Réne W.M.M. Jansen M749 Functional Magnetic Resonance Imaging of Odor Identification: The Effect of Aging Yusuke Suzuki, Hugo D. Critchley, John Suckling, Rimmei Fukuda, Steven C.R. Williams, Chris Andrew, Robert Howard, Emma Ouldred, Catherine Bryant, Cameron G. Swift, and Stephen H.D. Jackson M756 Fall Risk Assessment Measures: An Analytic Review .. . ; Karen L. Perell, Audrey Nelson, Ronald L. Goldman, Stephen L. Luther, Nicole Prieto-Lewis, and Laurence Z. Rubenstein M761 A New Approach of Measuring Muscle Impairment During a Functional Task: Quadriceps Muscle Activity Recorded During Chair Stand ree Jennifer S. Brach, Andrea M. Kriska, Anne B. Newman, and Jessie M. VanSwearingen M767 The Characterization of Reenchinaivesier Lavage Fluid in Very Elderly Patients With Cerebrovascular Disease .......... Masayuki Kikawada, Tetsuo Oyama, Kimikazu Ogawa, Hisayuki Arai, Toshihiko Jwamnot, and Masaru Takasaki M771 Cobalamin Supplementation Improves Cognitive and Cerebral Function in Older, Cobalamin Deficient Persons . Dieneke Z. van Assellt, Jaco W. Pasman, Henk J. van Lier, Dick M. Vingerhoets, PetraJ . Poels, Yolande Kuin, Henk J. Blom, and Willibrord H. Hoefnagels M775 Height and Body Weight in Elderly Adults: A 21-Year Population Study on Secular Trends and Related Factors in 70-Year-Olds . Debashish Kumar Dey, Elisabet Rothenberg, Valter Sundh, Ingvar Bosaeus, and Bertil Steen M780 The APOE -E4 Allele and theR isk of Functional Decline in a Community Sample of African American and White Older Adults Dan G. Blazer, Gerda Fillenbaum, and Bruce Burchett M785 Improving Food Intake in Nursing Home Residents With Feeding Assistance: A Staffing Analysis .. Sandra F. Simmons, Dan Osterweil, and John F. Schnelle M790 An Instrument to Measure Healing in Pressure Ulcers: Development and Validation of the Pressure Ulcer Scale for Healing (PUSH) Nancy A. Stotts, George T. Rodeheaver, David R. Thomas, Rita A. Frantz, Alfred A. Bartolucci, Carrie Sussman, Bruce A. Ferrell, Janet Cuddigan, and JoAnn Maklebust for the PUSH Task Force M795 Volume Contents and Index M&s00 M804 P F CAN. We ee eyP ee e e eY e

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