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The Journal of Steroid Biochemistry and Molecular Biology 2001: Vol 79 Table of Contents PDF

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The Journal of Steroid Biochemistry & Molecular Biology kditor-in-Chief J.R. PASOUALINI VOLUME CONTENTS, SUBJECT AND AUTHOR INDEX Volume 79 The Journal of Steroid Biochemistry and Molecular Biology EDITOR-IN-CHIEF J. R. Pasqualini Steroid Hormone Research Unit. Institut de Puériculture, 26 Boulevard Brune, 75014 Paris, France Tel.: +33-1-45399109; Fax: +33-1-45426121; E-mail: jorge.pasqualini(@ wanadoo.fr HONORARY EDITOR-IN-CHIEF R. Scholler CORRESPONDING EDITORS M. Beato, Marburg/Lahn, Germany J.-A. Gustafsson, Huddinge, Sweden Jj. Paris, Monaco A. S. Bhatnagar, Basel, Switzerland K. B. Horwitz, Denver, U.S.A. M. G. Parker, London, U.K. R. Bouillon, Leuven, Belgium I. Huhtaniemi, lurku, Finland G. Perez-Palacios, Mexico City, Mexico A. Brodie, Baltimore, U.S.A. V. C. Jordan, Chicago, U.S.A. J. P. Raynaud, Paris, France K. J. Catt, Bethesda, U.S.A. J. Kato, ‘Tokyo, Japan R. Renkawitz, Giessen, Germany G. Chetrite, Paris, France B. S. Katzenellenbogen, Urbana, U.S.A. H. Rochefort, Montpellier, France Jj. A. Cidlowski, Research ‘lriangle Park, A. M. Kaye, Rehovot, Israel E. R. Sanchez, loledo, U.S.A. U.S.A. J. Kitawaki, Kyoto, Japan B. Sato, Osaka, Japan P. D. Darbre, Reading, U.K. E. R. de Kloet, Leiden, The Netherlands M. Serio, Florence, Italy G. Daxenbichler, Innsbruck, Austria H. J. Kloosterboer, Oss, The Netherlands E. R. Simpson, Clayton, Australia A. De Nicola, Buenos Aires, Argentina F. Labrie, Quebec, Canada C. Sonnenschein, Boston, U.S.A. E. R. DeSombre, Chicago, U.S.A. S. Liao, Chicago, U.S.A. L. Starka, Prague, Czech Republic B. N. Diaz-Chico, Las Palmas, Spain V. B. Mahesh, Augusta, U.S.A. R. L. Sutherland, Darlinghurst, Australia R. B. Dickson, Washington, U.S.A. L. Martini, Milan, Italy J. H. H. Thijssen, UtrechtT,h e Netherlands M. Dowsett, London, U.K. B. S. McEwen, New York, U.S.A. D. O. Toft, Rochester, MN, U.S.A. M. L. Dufau, Bethesda, U.S.A. H. Michna, Cologne, Germany P. Tuohimaa, lampere, Finland D. P. Edwards, Denver, U.S.A. E. Milgrom, Le Kremlin-Bicétre, France G. Verhoeven, Leuven, Belgium H. A. Eriksson, Stockholm, Sweden L. J. Murphy, Winnipeg, Canada P. Vihko, Oulu, Finland J. W. Funder, Prahran, Australia A. Naray-Fejes-Toth, Hanover, U.S.A. G. Vollmer, Dresden, Germany S. A. Fuqua, Houston, U.S.A. M. I. New, New York, U.S.A. C. R. Wira, Hanover, U.S.A G. Greene, Chicago, U.S.A. A. W. Norman, Riverside, U.S.A. B. Groner, Frankfurt am Main, Germany T. Ojasoo, Montrouge, France HONORARY ASSOCIATE EDITORS H. Adlercreutz, Helsinki, Finland E. V. Jensen, Hamburg, Germany R. J. B. King, Guildford, UK. Publication Frequency: Published semi-monthly in 4 volumes. Publication information: [he Journal of Steroid Biochemistry and Molecular Biology (ISSN 0960-0760). For 2001, volumes 76~-79 are scheduled for publication. Subscription prices are available upon request from the Publisher or from the Regional Sales Office near- est you or from this journal's website (http://www.elsevier.com/locate/jsbmb). Further information is available on this journal and other Elsevier Science products through Elsevier’s website: (http://www.elsevier.com). Subscriptions are accepted on a prepaid basis only and are entered on a calendar year basis. Issues are sent by standard mail (surface within Europe, air delivery outside Europe). Priority rates are available upon request. Claims for missing issues should be made within six months of the date of dispatch. Periodicals postage paid at Rahway, New Jersey. The Journal of Steroid Biochemistry and Molecular Biology (ISSN 0960-0760) is pub- lished semi-monthly in 4 volumes by Elsevier Science Ltd., The Boulevard, Langford Lane, Kidlington, Oxford OX5 IGB, UK. The annual subscription in the USA is $3,768.00. The Journal of Steroid Biochemistry and Molecular Biology is circulated by Mercury International Limited, 365 Blair Road, Avenel, NJ 07001, USA. POSTMASTER: Please send address corrections to The Journal of Steroid Biochemistry and Molecular Biology:, c/o Customer Ser- vices, Elsevier Science Inc., 655 Avenue of the Americas, New York, NY 10010, USA. C) 2002 Elsevier Science Ltd. All rights reserved The Journal of Steroid Biochemistry & Molecular Biology PERGAMON Journal of Steroid Biochemistry & Molecular Biology 79 (2001) III-V www.elsevier.com/locate/jsbmb List of Contents DECEMBER 2001 Vol. 79, Nos. 1-5 Evan Simpson and Jorge Pasqualini | Preface Models of aromatase Insufficiency and Excess Margaret E.E. Jones, Anne W. Thorburn, 3 Aromatase-deficient (ArKO) mice accumulate excess adipose tissue Kara L. Britt, Kylie N. Hewitt, Marie L. Misso, Nigel G. Wreford, Joseph Proietto, Orhan K. Oz, Brian J. Leury, Kirsten M. Robertson, Shenggen Yao and Evan R. Simpson Katsumi Toda, Kiyoshi Takeda, Shizuo Akira, 11 Allternationsi n hepatic expresofs faittoy-anci d metabolizing enzymesi n ArKO mice and Toshiji Saibara, Teruhiko Okada, Saburo Onishi their reversal by the treatment with 17{-estradiol or a peroxisome proliferator and Yutaka Shizuta Serdar E. Bulun, Sijun Yang, Zongjuan Fang, 19 Role of aromatase in endometrial disease Bilgin Gurates, Mitsutoshi Tamura, Jianfeng Zhou and Siby Sebastian Usha Mandava, Nameer Kirma and 27 Aromatase overexpression transgenic mice model: cell type specific expression and use Rajeshwar Rao Tekmal of letrozole to abrogate mammary hyperplasia without affecting normal physiology Aromatase expression in breast and bone Shiuan Chen, Dujin Zhou, Chun Yang, 35 Modulation of aromatase expression in human breast tissue Tomoharu Okubo, Yoshiyuki Kinoshita, Bin Yu, Yeh-Chih Kao and Toru Itoh A.M.H. Brodie, Q. Lu, B.J. Long, A. Fulton, 41 Aromatase and COX-2 expression in human breast cancers T. Chen, N. Macpherson, P.C. DeJong, M.A. Blankenstein, J.W.R. Nortier, P.H.T.J. Slee, J. van de Ven, J.M.H.H. van Gorp, J.R.J. Elbers, M.E.I. Schipper, G.H. Blijham and J.H. Thijssen Orhan K. Oz, Gen Hirasawa, Jonathan Lawson, 49 Bone phenotype of the aromatase deficient mouse Lydia Nanu, Anca Constantinescu, Peter P. Antich, Ralph P. Mason, Edward Tsyganov, Robert W. Parkey, Joseph E. Zerwekh and Evan R. Simpson Makio Shozu, Hiroshi Sumitani, 61 Regulation of aromatase activity in bone-derived cells: possible role of mitogen-acti- Kouichi Murakami, Tomoya Segawa, vated protein kinase Hei-Juan Yang and Masaki Inoue Aromatase expression in cardiovascular system Hiroshi Murakami, Nobuhiro Harada and 67 Aromatase in atherosclerotic lesions of human aorta Hironobu Sasano Pharmacology (clinical session) Robert W. Brueggemeier, Jeanette A. Richards, 75. Molecular pharmacology of aromatase and its regulation by endogenous and exogenous Surachai Joomprabutra, Abhijit S. Bhat and agents Jennifer L. Whetstone PII: S0960-0760(01)00192-3 IV List of Contents I.M. Boeddinghaus and M. Dowsett Comparative clinical pharmacology and pharmacokinetic interactions of aromatase inhi- bitors W.R. Miller and J.M. Dixon 93 Local endocrine effects of aromatase inhibitors within the breast Neoadjuvant therapy (clinical session) W.R. Miller, J.M. Dixon, D.A. Cameron and 103 Biological and clinical effects of aromatase inhibitors in neoadjuvant therapy T.J. Anderson Advanced disease (clinical session) Aman U. Buzdar 109 A summary of second-line randomized studies of aromatase inhibitors Richard Santen, Meei-Huey Jeng, Ji-Ping Wang, Adaptive hypersensitivity to estradiol: potential mechanism for secondary hormonal Robert Song, Shigeru Masamura, responses in breast cancer patients Robert McPherson, Steven Santner, Wei Yue and Woo-Shin Shim Per Eystein Lonning 127 Stepwise estrogen suppression manipulating the estrostat Adjuvant therapy, prevention and future (clinical session) Joseph Ragaz Adjuvant trials of aromatase inhibitors: determining the future landscape of adjuvant endocrine therapy Paul E. Goss and Kathrin Strasser 143 Chemoprevention with aromatase inhibitors—trial strategies Aromatase in breast tissue Nobuhiro Harada, Takahiro Matsumoto, Analysis of transcriptional regulation of human breast aromatase by in vitro and in vivo Noriko Yoshimura, Hideo Sakamoto and studies Shin-ichiro Honda Wei Yue, Lev M. Berstein, Ji-Ping Wang, The potential role of estrogen in aromatase regulation in the breast Gary M. Clark, Christopher J. Hamilton, Laurence M. Demers and Richard J. Santen D. Parish, A. Purohit, A. Singh, J. Rosankiewicz, 165 Peptide inhibition of cytokine-stimulated aromatase activity in breast tissue fibroblasts M.W. Ghilchik and M.J. Reed Aromatase and reproduction Amrita Kamat and Carole R. Mendelson Identification of the regulatory regions of the human aromatase P450 (CYP/9) gene involved in placenta-specific expression Kara L. Britt, Ann E. Drummond, 18] The ovarian phenotype of the aromatase knockout (ArKO) mouse Mitzilee Dyson, Nigel G. Wreford, Margaret E.E. Jones, Evan R. Simpson and Jock K. Findlay Toshihiko Yanase, Yi-Ming Mu, Yoshihiro Nishi, 187 Regulation of aromatase by nuclear receptors Kiminobu Goto, Masatoshi Nomura, Taijirou Okabe, Ryoichi Takayanagi and Hajime Nawata Margaret M. Hinshelwood and 193 Tissue-specific expression of the human CYP/9 (aromatase) gene in ovary and adipose Carole R. Mendelson tissue of transgenic mice S. Carreau, S. Bourguiba, S. Lambard, 203 Aromatase expression in male germ cells I. Galeraud-Denis, C. Genissel, B. Bilinska, M. Benahmed and J. Levallet New therapeutic approaches J.F.R. Robertson 209 Faslodex (ICI 182, 780), a novel estrogen receptor downregulator—future possibilities in breast cancer Fernand Labrie, Claude Labrie, Alain Bélanger, EM-652 (SCH57068), a pure SERM having complete antiestrogenic activity in the i) td Jacques Simard, Vincent Giguere, mammary gland and endometrium André Tremblay and Gilles Tremblay List of Contents V Anthony Howell, Sacha J. Howell, Robert Clarke 227 Where do selective estrogen receptor modulators (SERMs) and aromatase inhibitors and Elizabeth Anderson (Als) now fit into breast cancer treatment algorithms? Aromatase expression in brain Gil Mor, Mariel Eliza, Joon Song, Brinda Wiita, 239 17%-Methyl testosterone is a competitive inhibitor of aromatase activity in Jar chorio- Shiuan Chen and Frederick Naftolin carcinoma cells and macrophage-like THP-1 cells in culture Charles E. Roselli and John A. Resko 247 Cytochrome P450 aromatase (CYP19) in the non-human primate brain: distribution, regulation, and functional significance Shin-Ichiro Honda, Takahiro Matsumoto and Characterization and purification of a protein binding to the cis-acting element for brain- Nobuhiro Harada specific exon | of the mouse aromatase gene Jacques Balthazart, Michelle Baillien and 261 Phosphorylation processes mediate rapid changes of brain aromatase activity Gregory F. Ball Aromatase expression in other species Jens Vanselow, Rainer Fiirbass, Attila Zsolnai, 279 Expression of the aromatase cytochrome P450 encoding gene in cattle and sheep Claudia Kalbe, Harun M. Said and M. Schwerin Alan Conley, Samantha Mapes, C.J. Corbin, 289 A comparative approach to structure—function studies of mammalian aromatases Doug Greger, Karen Walters, John Trant and Sandra Graham Sok-Keng Tong, Evelyn Feng-lin Chiang, 299 Phylogeny, expression and enzyme activity of zebrafish cyp/9 (P450 aromatase) genes Pei-Hung Hsiao and Bon-chu Chung Gloria V. Callard, Anna V. Tchoudakova, 305 Differential tissue distribution, developmental programming, estrogen regulation and Mitsuyo Kishida and Elizabeth Wood promoter characteristics of cyp/9 genes in teleost fish Contents index for Volume 79 (2001) Vi Subject index for Volume 79 (2001) Vill Author index for Volume 79 (2001)

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