The Journal of Steroid Biochemistry & Molecular Biology Editors-in-chief J. R. PASQUALINI and R. SCHOLLER VOLUME CONTENTS, SUBJECT AND AUTHOR INDEX Volume 59 The Journal of Steroid Biochemistry and Molecular Biology EDITOR-IN-CHIEF J. R. Pasqualini Institut de Puériculture, 26 Boulevard Brune, 75014 Paris, France HONORARY EDITOR-IN-CHIEF R. Scholler Institute de Puériculture, 26 Boulevard Brune, 75014 Paris, France ASSOCIATE EDITORS M. Beato, Marburg/Lahn, Germany M. E. Lippman, Washington, DC, U.S.A. B. Groner, Freiburg, Germany L. Martini, Milan, Italy E. Gurpide, New York, U.S.A. A. Munck, Hanover, NH, U.S.A. J.-A. Gustafsson, Huddinge, Sweden B. W. O’Malley, Houston, TX, U.S.A. J. Kato, Ichihara, Chiba, Japan D. O. Toft, Rochester, MN, U.S.A. CORRESPONDING EDITORS A. Aakvaag, Bergen, Norway - Greene, Chicago, U.S.A. G. Pérez-Palacios, Mexico City, Mexico A. S. Bhatnagar, Basel, Switzerland . Gronemeyer, Strasbourg, France W. B. Pratt, Ann Arbor, U.S.A. R. Bouillon, Leuven, Belgium . B. Horwitz, Denver, U.S.A. J. P. Raynaud, Paris, France A. Brodie, Baltimore, U.S.A. - Huhtaniemi, Turku, Finland R. Renkawitz, Giessen, Germany M. Bronnegard, Huddinge, Sweden . C. Jordan, Chicago, U.S.A. H. Rochefort, Montpellier, France M. L. Casey, Dallas, U.S.A. . S. Katzenellenbogen, Urbana, U.S.A. B. Sato, Osaka, Japan . J. Catt, Bethesda, U.S.A. . M. Kaye, Rehovot, Israel M. Serio, Florence, Italy - Chetrite, Paris, France E. R. de Kloet, Leiden, The Netherlands E. R. Simpson, Dallas, U.S.A. . A. Cidlowski, Research Triangle Park, H. J. Kloosterboer, Oss, The Netherlands L. Starka, Prague, Czech Republic U.S.A. F. Labrie, Quebec, Canada J. F. Strauss III, Philadelphia, U.S.A. - D. Darbre, Reading, U.K. S. Liao, Chicago, U.S.A. R. L. Sutherland, Darlinghurst, Australia - Daxenbichler, Innsbruck, Austria V. B. Mahesh, Augusta, U.S.A. J. R. Tata, London, U.K. MPOO- URDTe Nicola, Buenos Aires, Argentina B. S. McEwen, New York, U.S.A. W. Taylor, Tynemouth, U.K. - R. DeSombre, Chicago, U.S.A. H. Michna, Cologne,) Germany J. H. H. Thijssen, Utrecht, . N. Diaz-Chico, Las Palmas, Spain E. Milgrom, Le Kremlin-Bicétre, France The Netherlands tAh . wB. Dickson, Washington, U.S.A. J. Miller, Zurich, Switzerland P. Tuohimaa, Tampere, Finland M - Dowsett, London, U.K. L. J. Murphy, Winnipeg, Canada G. Verhoeven, Leuven, Belgium M . L. Dufau, Bethesda, U.S.A. A. Naray-Fejes-Toth, Hanover, U.S.A. A. Vermeulen, Ghent, Belgium . P. Edwards, Denver, U.S.A. M. I. New, New York, U.S.A. R. Vihko, Oulu, Finland . A. Eriksson, Stockholm, Sweden A. W. Nor.nan, Riverside, U.S.A. A. E. Wakeling, Macclesfield, U.K. . W. Funder, Prahran, Australia T. Ojasoo, Montrouge, France C. R. Wira, Hanover, U.S.A. AISS. A. Fuqua, San Antonio, U.S.A. M. G. Parker, London, U.K. T. Yamamoto, Kyoto, Japan HONORARY ASSOCIATE EDITORS H. Adlercreutz, Helsinki, Finland E. V. Jensen, Hamburg, Germany R. J. B. King, Guildford, U.K. Publishing Office (Production Editor. Amanda Booth) Elsevier Science Ltd, The Boulevard, Langford Lane, Kidlington, Oxford OX5 1GB, U.K. Subscription and Advertising Offices North America: Elsevier Science Regional Sales Office, Customer Support Department, 655 Avenue of the Americas, New York, NY 10010, U.S.A. Rest of the World: Elsevier Science Ltd, The Boulevard, Langford Lane, Kidlington, Oxford OX5 1GB, U.K. [Tel: Oxford (01865) 843000; Fax: (01865) 843010] Publication Frequency (1996) Published 14 issues in 1996, monthly plus extra issues in January and December. Subscription Rates (1997) Annual Institutional Subscription Rates 1997: Europe, The CIS and Japan 4048.00 Dutch Guilders. All other countries US$2499.00. Associated Personal Subscription rates are available on request for those whose institutions are library subscribers. Dutch Guilder prices exclude VAT. 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The Journal of Steroid Biochemistry & Molecular Biology is distributed by Mercury Airfreight International Ltd, 10 Camptown Road, Irvington, NJ 07111-1105. POSTMASTER: please send address changes to The Journal of Steroid Biochemistry & Molecular Biology, c/o Elsevier Science RSO, Customer Support Department, 655 Avenue of the Americas, New York, NY 10010, U.S.A. [Tel: (+1) 212 633 3730/1 888 4ES-INFO; fax: (+1) 212 633 3680; e-mail: [email protected]]. Copyright © 1996 Elsevier Science Ltd. All rights reserved LIST OF CONTENTS SEPTEMBER Jiro Fujimoto, Masashi Hori, Satoshi Ichigo and Sex steroids regulate the expression of plasminogen activator inhibitor-1 (PAI-1) Teruhiko Tamaya and its mRNA in uterine endometrial cancer cell line Ishikawa Tianshu Gao, Marco Marcelli and Transcriptional activation and transient expression of the human androgen receptor Michael J. McPhaul Michelle Demeter Arlotto, M. Dodson Michael, 17a-Hydroxylase gene expression in the bovine ovary: mechanisms regulating Michael W. Kilgore and Evan R. Simpson expression differ from those in adrenal cells Bruce A. Lessey, Abiodun O. Ilesanmi, Characterization of the functional progesterone receptor in an endometrial Arthur J. Castelbaum, Lingwen Yuan, adenocarcinoma cell line (Ishikawa): progesterone-induced expression of the a1 Steven G. Somkuti, Pondichery G. Satyaswaroop integrin and Kristof Chwalisz Pui-Kai Li, Shawn Milano, Lisa Kluth and Synthesis and sulfatase inhibitory activities of non-steroidal estrone sulfatase Michael E. Rhodes inhibitors A. Bonfils, J. Humbert and D. Philibert RU 3117 a steroidal compound with high affinity for sigma sites in rat testis membranes Jamal Almadhidi, Safa Moslemi, Equine cytochrome P450 aromatase exhibits an estrogen 2-hydroxylase activity Michel A. Drosdowsky and Gilles-Eric Séralini in vitro C. Lobaccaro-Henri, B. Descomps and RU 38486 inhibits intracellular calcium mobilization and PGI2 release from human H. Thaler-Dao myometrium: mechanism of action C. Schubert, J. Donath, H. Michna and Y. Nishino The antiovulatory activity of progesterone antagonists is not correlated to their antiprogestational potency in the rat Kyle W. Selcer, Sharada Jagannathan, Inhibition of placental estrone sulfatase activity and MCF-—7 breast cancer cell Michael E. Rhodes and Pui-Kai Li proliferation by estrone-3-amino derivatives Jill M. O’Reilly and Robert W. Brueggemeier 7a-Arylaliphatic androsta-1,4-diene-3,17-diones as enzyme-activated irreversible inhibitors of aromatase Jacques Quivy, Guy Leclercq, Marcel Deblaton, Synthesis, structure and biological properties of Z-17a-(2-iodovinyl)-11-chloro- Pierre Henrot, Nicolas Velings, Bernadette methyl estradiol-17f (Z-CMIV), a high affinity ligand for the characterization of Norberg, Guy Evrard and Marc Zeicher estrogen receptor-positive tumors Book Reviews OCTOBER Mary E. Herman and Benita S. Kat Response-specific antiestrogen resistance in a newly characterized MCF-7 human breast cancer cell line resulting from long-term exposure to trans-hydroxytamoxifen Erin C. Jacobs, Arthur P. Arnold and Zebra finch estrogen receptor cDNA: cloning and mRNA expression Anthony T. Campagnoni Carlos Sonnenschein, Ana M. Soto and Human serum albumin shares the properties of estrocolyone-I, the inhibitor of the Cheryl L. Michaelson proliferation of estrogen-target cells Jeffrey A. Dodge, Andrew L. Glasebrook, Environmental estrogens: effects on cholesterol lowering and bone in the David E. Magee, David L. Phillips, ovariectomized rat Masahiko Sato, Lorri L. Short and Henry U. Bryant Changbao Zhou, Dujin Zhou, Jose Esteban, Aromatase gene expression and its exon I usage in human breast tumors. Detection James Murai, Pentti K. Siiteri, of aromatase messenger RNA by reverse transcription—polymerase chain reaction Sharon Wilczynski and Shiuan Chen Zsuzsanna Vértes, J. L. Kérnyei, S. Kovacs and Opioids regulate cell proliferation in the developing rat uterus: effects during the Marietta Vértes period of sexual maturation Ill IV List of Contents Oskari Heikinheimo, Jeng-Gwang Hsiu, Endometrial effects of RU486 in primates— antiproliferative action despite signs of Keith Gordon, Seokjoong Kim, estrogen action and increased cyclin-B expression Robert F. Williams, William E. Gibbons and Gary D. Hodgen Pascal Sourdaine, Peter Mullen, Roger White, Aromatase activity and CYP19 gene expression in breast cancers June Telford, Malcolm G. Parker and William R. Miller Ray V. Haning Jr, Umadevi Tantravahi, 5a-Reductase 1 and 2 expression and activity in human ovarian follicles, stroma and Qianying Zhao, Richard J. Hackett and corpus luteum as compared to neonatal foreskin Jacob A. Canick Tea Lanisnik Rizner, Marija Zakelj-Mavrié, Purification and characterization of 17f-hydroxysteroid dehydrogenase from the Ana Plemenitas and Matjaz Zorko filamentous fungus Cochliobolus lunatus M. M. Singh, R. N. Trivedi, S. C. Chauhan, Uterine estradiol and progesterone receptor concentration, activities of certain V. M. L. Srivastava, A. Makker, antioxidant enzymes and dehydrogenases and histoarchitecture in relation to time S. R. Chowdhury and V. P. Kamboj of secretion of nidatory estrogen and high endometrial sensitivity in rats M. D. Ferrandez, M. de la Fuente, E. Fernandez Anabolic steroids and lymphocyte function in sedentary and exercise-trained rats and R. Manso Gianna Fiorelli, Francesca Gori, Uliana Frediani, Membrane binding sites and non-genomic effects of estrogen in cultured human RrEr, RrKr. helli, Annalisa Tanini, pre-osteoclastic cells Cristina Tosti-Guerra, Susanna Benvenuti, Luigi Gennari, Lucia Becherini and Maria Luisa Brandi Book Reviews NOVEMBER Robert Snoek, Paul S. Rennie, Susan Kasper, Induction of cell-free, im vitro transcription by recombinant androgen receptor Robert J. Matusik and Nicholas Bruchovsky peptides Qiu-Xia Zhang, Sue G. Hilsenbeck, Multiple splicing variants of the estrogen receptor are present in individual human Suzanne A. W. Fuqua and Ake Borg breast tumors Dorraya El-Ashry, Susan A. Chrysogelos, Estrogen induction of TGF-« is mediated by an estrogen response element Marc E. Lippman and Francis G. Kern composed of two imperfect palindromes Célia Regina Nogueira and Maria Mitzi Brentani Triiodothyronine mimics the effects of estrogen in breast cancer cell lines D. E. Marshall, M. C. Dumasia, P. Wooding, Studies into aromatase activity associated with fetal allantochorionic and maternal D. B. Gower and E. Houghton endometrial tissues of equine placenta. Identification of metabolites by gas chromatography mass spectrometry Katherine H. Moore, Kenneth A. Bertram, Sex hormone binding globulin mRNA in human breast cancer: detection in cell Richard R. Gomez, M. J. Styner and lines and tumor samples Louis A. Matej L. D. Dikkeschei, B. G. Wolthers, I. Bos-Zuur, Optimization of a classical aromatase activity assay and application in normal, G. Brutel de la Riviere, G. T. Nagel, adenomatous and malignant breast parenchyma D. A. van der Kolk and P. H. B. Willemse Jerome V. A. Choate and John A. Resko Effects of androgen on brain and pituitary androgen receptors and LH secretion of male guinea pigs B. Lyoussi and J. Crabbé Effects of corticosteroids on parameters related to Na* transport by amphibian renal distal cells (A6) in culture B. Lyoussi and J. Crabbé Effects of dexamethasone on (Na*+K*)-ATPase and other parameters related to transepithelial Na* transport by amphibian renal distal cells (A6) in culture P. Belvedere, G. Gabai, L. Dalla Valle, P. Accorsi, Occurrence of steroidogenic enzymes in the bovine mammary gland at different M. Trivoletti, L. Colombo and G. Bono functional stages Book Reviews List of Contents DECEMBER Editorial J. R. Pasqualini, C. Campagnoli, R. Druckmann, Progestins: present and future J. Huber, K. W. Schweppe, J. H. H. Thijssen and A. E. Schindler Michael E. Baker Bacterial 3a-hydroxysteroid dehydrogenase is homologous to a fusion of bacterial ribosomal L10 and L7/12 genes Kazuko Wada, Shintaro Nomura, Eiichi Morii, Changes in levels of mRNAs of transforming growth factor (TGF)-f1, -2, -f3, Yukihiko Kitamura, Yasuko Nishizawa, TGF-f type II receptor and sulfated glycoprotein-2 during apoptosis of mouse Akira Miyake and Nobuyuki Terada uterine epithelium Nicholas J. Koszewski, Timothy A. Reinhardt and Vitamin D receptor interactions with the murine osteopontin response element Ronald L. Horst D. Sémjen, A. Waisman and A. M. Kaye Tissue selective action of tamoxifen methiodide, raloxifene and tamoxifen on creatine kinase B activity in vitro and in vivo Nicholas Bruchovsky, Marianne D. Sadar, Characterization of 5a-reductase gene expression in stroma and epithelium of Koichiro Akakura, S. Larry Goldenberg, human prostate Kei Matsuoka and Paul S. Rennie Mei-Ling Siu-Caldera, Jeffrey W. Clark, 1a,25-dihydroxy-24-oxo-16-ene vitamin D3, a metabolite of a synthetic vitamin D, Anabela Santos-Moore, Sara Peleg, analog, 1a,25-dihydroxy-16-ene vitamin D3, is equipotent to its parent in Yan Yun Liu, Milan R. Uskokovic, medulating growth and differentiation of human leukemic cells Surendra Sharma and G. Satyanarayana Reddy Jennifer H. Anolik, Carolyn M. Klinge, Stability of the ligand-estrogen receptor interaction depends on estrogen response Colleen L. Brolly, Robert A. Bambara and element flanking sequences and cellular factors Russell Hilf Ronald L. Kabler, Arvind Srinivasan, Androgen regulation of ribosomal RNA synthesis in LNCaP cells and rat prostate Laura J. Taylor, Joseph Mowad, Lawrence I. Rothblum and Alice H. Cavanaugh R. B. Myers, D. K. Oelschlager, R. D. Hockett, M. The effects of dihydrotestosterone on the expression of p185‘°®? and c-erbB-2 D. Rogers, B. A. Conway-Myers and W. E. mRNA in the prostatic cell line LNCaP Grizzle P. Van de Velde, F. Nique, P. Planchon, RU 58668: further im vitro and in vivo pharmacological data related to its G. Prévost, J. Bremaud, M. C. Hameau, antitumoral activity V. Magnien, D. Philibert and G. Teutsch Xilin Su, Linda Schuler and Sander Shapiro Cloning and characterization of a glycogen synthase cDNA from human endometrium Thomas C. Wood, Chengtao Her, Ibrahim Aksoy, Human dehydroepiandrosterone sulfotransferase pharmacogenetics: quantitative Diane M. Otterness and Western analysis and gene sequence polymorphisms Richard M. Weinshilboum Ronald Hobkirk Sulfation by guinea pig chorion and uterus: differential action towards estrone and estradiol Keiko Kobayashi, Shuji Ohno, Masato Shinoda, Immunochemical distribution and immunohistochemical localization of 20f- Satoshi Toyoshima and Shizuo Nakajin hydroxysteroid dehydrogenase in neonatal pig tissues A. M. Stoka Activity of juvenile hormone and juvenile hormone analogues on the growth of Trypanosoma cruzi Koichiro Akakura, Nicholas Bruchovsky, Effects of intermittent androgen suppression on the stem cell composition and the Paul S. Rennie, Andrew J. Coldman, expression of the TRPM-2 (clusterin) gene in the Shionogi carcinoma S. Larry Goldenberg, Martin Tenniswood and Kelly Fox