Table Of Content

Volume Contents Volume 202, Number | January 2004 Commentary Human papillomavirus integration: detection by in situ hybridization and potential clinical application MF Evans and Review Article Are tumours angiogenesis-dependent? HMW Verheul, EE Voest and RO Schlingemann Original Papers Differential expression of matrilysin-1 (MMP-7), 92 kD gelatinase (MMP-9), and metalloelastase (MMP-12) in oral verrucous and squamous cell cancer U Impola, VJ Uitto, J Hietanen, L Hakkinen, L Zhang, H Larjava, K Isaka and U Saarialho-Kere .. iaecuaedaiiatiadiemnatainons Transition of high-grade cervical intraepithelial neoplasia to micro-invasive carcinoma is characterized by integration of HPV 16/18 and numerical chromosome abnormalities AHN Hopman, F Smedts, W Dignef, M Ummelen, G Sonke, M Mravufiac, GP Vooijs, E-JM Speel and FCS Ramaekers Expression of interleukin-6 and monocyte chemoattractant protein-1 by peritoneal sub-mesothelial cells during abdominal operations J Riese, G Niedobitek, R Lisner, A Jung, W Hohenberger and W Haupt Immunohistochemical analysis of the IL-6 family of cytokines and their receptors in benign, hyperplasic, and malignant human prostate M Royuela, M Ricote, MS Parsons, I Garcia-Tunon, R Paniagua and MP De Miguel Blockade of the type | IGF receptor expression in human prostate cancer cells inhibits proliferation and invasion, up-regulates IGF binding protein-3, and suppresses MMP-2 expression M Grzmil, B Hemmerlein, P Thelen, S Schweyer and P Burfeind Differential Eu enhancer activity and expression of BOB.1/OBF.1, Oct 2, PU.1, and immunoglobulin in reactive B-cell populations, B-cell non-Hodgkin lymphomas, and Hodgkin lymphomas C Loddenkemper, I Anagnostopoulos, M Hummel, K JOhrens-Leder, H-D Foss, F Jundt, T Wirth, B Dorken and H Stein Presence and localization of T-cell subsets in relation to melanocyte differentiation antigen expression and tumour regression as assessed by immunohistochemistry and molecular analysis of microdissected T cells MR Bernsen, JHS Diepstra, P van Mil, CUA Punt, CG Figdor, GNP van Muijen, GJ Adema and DJ Ruiter Absence of c-kit gene mutations in gastrointestinal stromal tumours from neurofibromatosis type 1 patients K Kinoshita, S Hirota, K Isozaki, A Ohashi, T Nishida, Y Kitamura, Y Shinomura and Y Matsuzawa Differential expression of the calcium sensing receptor and combined loss of chromosomes lq and 11q in parathyroid carcinoma CJ Haven, M van Puijenbroek, M Karperien, G-J Fleuren and H Morreau Evaluation of MDM2 and CDK4 amplification by real-time PCR on paraffin wax-embedded material: a potential tool for the diagnosis of atypical lipomatous tumours/well-differentiated liposarcomas I Hostein, M Pelmus, A Aurias, F Pedeutour, S Mathoulin-Pélissier and JM Coindre Fibroblast growth factor 2 induces differentiation and apoptosis of Askin tumour cells M-S Kim, CJ Kim, HS Jung, MR Seo, Y-S Juhnn, HY Shin, HS Ahn, CJ Thiele and JG Chi Expression of cartilage growth plate signalling molecules in chondroblastoma S Romeo, JVMG Bovée, NAA Jadnanansing, AHM Taminiau and PCW Hogendoorn Hypertrophic scar formation is associated with an increased number of epidermal Langerhans cells FB Niessen, J Schalkwijk, H Vos and W Timens A fluid cover medium provides superior morphology and preserves RNA integrity in tissue sections for laser microdissection and pressure catapulting P Micke, T Bjarnsen, S Scheidl, S Stro6mberg, J-B Demoulin, F Ponten, A Ostman, P Lindahl and C Busch Announcement Volume Contents Volume 202, Number | January 2004 Commentary Human papillomavirus integration: detection by in situ hybridization and potential clinical application MF Evans and Review Article Are tumours angiogenesis-dependent? HMW Verheul, EE Voest and RO Schlingemann Original Papers Differential expression of matrilysin-1 (MMP-7), 92 kD gelatinase (MMP-9), and metalloelastase (MMP-12) in oral verrucous and squamous cell cancer U Impola, VJ Uitto, J Hietanen, L Hakkinen, L Zhang, H Larjava, K Isaka and U Saarialho-Kere .. iaecuaedaiiatiadiemnatainons Transition of high-grade cervical intraepithelial neoplasia to micro-invasive carcinoma is characterized by integration of HPV 16/18 and numerical chromosome abnormalities AHN Hopman, F Smedts, W Dignef, M Ummelen, G Sonke, M Mravufiac, GP Vooijs, E-JM Speel and FCS Ramaekers Expression of interleukin-6 and monocyte chemoattractant protein-1 by peritoneal sub-mesothelial cells during abdominal operations J Riese, G Niedobitek, R Lisner, A Jung, W Hohenberger and W Haupt Immunohistochemical analysis of the IL-6 family of cytokines and their receptors in benign, hyperplasic, and malignant human prostate M Royuela, M Ricote, MS Parsons, I Garcia-Tunon, R Paniagua and MP De Miguel Blockade of the type | IGF receptor expression in human prostate cancer cells inhibits proliferation and invasion, up-regulates IGF binding protein-3, and suppresses MMP-2 expression M Grzmil, B Hemmerlein, P Thelen, S Schweyer and P Burfeind Differential Eu enhancer activity and expression of BOB.1/OBF.1, Oct 2, PU.1, and immunoglobulin in reactive B-cell populations, B-cell non-Hodgkin lymphomas, and Hodgkin lymphomas C Loddenkemper, I Anagnostopoulos, M Hummel, K JOhrens-Leder, H-D Foss, F Jundt, T Wirth, B Dorken and H Stein Presence and localization of T-cell subsets in relation to melanocyte differentiation antigen expression and tumour regression as assessed by immunohistochemistry and molecular analysis of microdissected T cells MR Bernsen, JHS Diepstra, P van Mil, CUA Punt, CG Figdor, GNP van Muijen, GJ Adema and DJ Ruiter Absence of c-kit gene mutations in gastrointestinal stromal tumours from neurofibromatosis type 1 patients K Kinoshita, S Hirota, K Isozaki, A Ohashi, T Nishida, Y Kitamura, Y Shinomura and Y Matsuzawa Differential expression of the calcium sensing receptor and combined loss of chromosomes lq and 11q in parathyroid carcinoma CJ Haven, M van Puijenbroek, M Karperien, G-J Fleuren and H Morreau Evaluation of MDM2 and CDK4 amplification by real-time PCR on paraffin wax-embedded material: a potential tool for the diagnosis of atypical lipomatous tumours/well-differentiated liposarcomas I Hostein, M Pelmus, A Aurias, F Pedeutour, S Mathoulin-Pélissier and JM Coindre Fibroblast growth factor 2 induces differentiation and apoptosis of Askin tumour cells M-S Kim, CJ Kim, HS Jung, MR Seo, Y-S Juhnn, HY Shin, HS Ahn, CJ Thiele and JG Chi Expression of cartilage growth plate signalling molecules in chondroblastoma S Romeo, JVMG Bovée, NAA Jadnanansing, AHM Taminiau and PCW Hogendoorn Hypertrophic scar formation is associated with an increased number of epidermal Langerhans cells FB Niessen, J Schalkwijk, H Vos and W Timens A fluid cover medium provides superior morphology and preserves RNA integrity in tissue sections for laser microdissection and pressure catapulting P Micke, T Bjarnsen, S Scheidl, S Stro6mberg, J-B Demoulin, F Ponten, A Ostman, P Lindahl and C Busch Announcement Volume Contents Volume 202, Number 2 February 2004 Perspective Emphysema: the challenge of the remodelled lung R Blundell, DJ Harrison and WAH Wallace Review Article Role of inflammatory mediators in the pathophysiology of acute respiratory distress syndrome M Bhatia and S Moochhala Original Papers Tissue and cellular tropism of the coronavirus associated with severe acute respiratory syndrome: an in-situ hybridization study of fatal cases KF To, JHM Tong, PKS Chan, FWL Au, SSC Chim, KCA Chan, JLK Cheung, EYM Liu, GMK Tse, AWI Lo, YMD Lo and HK Ng Expression of IL-27 in human Thl-associated granulomatous diseases F Larousserie, S Pflanz, A Coulomb-L’Herminé, N Brousse, R Kastelein and O Devergne The human Delta-like 1 homologue is implicated in the progression of liver fibrosis in biliary atresia C-C Huang, J-H Chuang, LLH Huang, M-H Chou, C-L Wu, C-M Chen, C-S Hsieh, S-Y Lee and C-L Chen A comparative study of mRNA and protein expression of the autoimmune regulator gene (Aire) in embryonic and adult murine tissues KA Adamson, SHS Pearce, JR Lamb, JR Seckl and SEM Howie ..............cccccccccccccecseeeecseececseveeevseceeeees .180 Expression of acyl-CoA synthetase 5 reflects the state of villus architecture in human small intestine N Gassler, J Kopitz, A Tehrani, B Ottenwalder, M Schnolzer, J Kartenbeck, S Lyer, F Autschbach, A Poustka, HF Otto and J Mollenhauer Gastric mucosal cytokine and epithelial cell responses to Helicobacter pylori infection in Mongolian gerbils JE Crabtree, M Court, MA Aboshkiwa, AHT Jeremy, MF Dixon and PA Robinson Expression of BUB1 protein in gastric cancer correlates with the histological subtype, but not with DNA ploidy or microsatellite instability HI Grabsch, JM Askham, EE Morrison, N Pomjanski, K Lickvers, WJ Parsons, A Boecking, HE Gabbert and W Mueller Expression of BRCA1 protein in benign, borderline and malignant epithelial ovarian neoplasms and its relationship to methylation and allelic loss of the BRCA1 gene C Wang, A Horiuchi, T Imai, S Ohira, K Itoh, T Nikaido, Y Katsuyama and I Konishi Altered expression of the ZBRK1 gene in human breast carcinomas V Garcia, G Dominguez, JM Garcia, J Silva, C Pena, JM Silva, E Carcereny, J Menendez, P Espana and F Bonilla Aberrant CpG island hypermethylation of multiple genes in prostate cancer and prostatic intraepithelial neoplasia GH Kang, S Lee, HJ Lee and KS Hwang Disrupted traffic of connexin 43 in human testicular seminoma cells: overexpression of Cx43 induces membrane location and cell proliferation decrease C Roger, B Mograbi, D Chevallier, JF Michiels, H Tanaka, D Segretain, G Pointis and P Fenichel BRAF mutations are associated with some histological types of papillary thyroid carcinoma V Trovisco, I Vieira de Castro, P Soares, V Maximo, P Silva, J Magalhaes, A Abrosimov, XM Guiu and M Sobrinho-Simoes Loss of heterozygosity at chromosome 9p21 is a frequent finding in enteropathy-type T-cell lymphoma EC Obermann, TC Diss, RA Hamoudi, P Munson, BS Wilkins, MLP Camozzi, PG Isaacson, MQ Du and A Dogan Announcements Volume Contents Volume 202, Number 3 March 2004 Original Papers Immunophenotypic analysis of inflammatory breast cancers: identification of an ‘inflammatory signature’ E Charafe- Jauffret, C Tarpin, V-J Bardou, F Bertucci, C Ginestier, A~-C Braud, B Puig, J Geneix, J Hassoun, D Birnbaum, J Jacquemier and Distribution and significance of 14-3-36, a novel myoepithelial marker, in normal, benign, and malignant breast tissue PT Simpson, T Gale, JS Reis-Filho, C Jones, S Parry, D Steele, A Cossu, M Budroni, G Palmieri and SR Lakhani Comparative multi-methodological measurement of ERBB2 status in breast cancer C Ginestier, E Charafe-Jauffret, F Penault-Llorca, J Geneix, J Adélaide, M Chaffanet, M-J Mozziconacci, J Hassoun, P Viens, D Birnbaum and J Jacquemier Distribution of laminins in the basement membranes of the upper gastrointestinal tract and Barrett’s oesophagus U Dave, MR Thursz, HY Ebrahim, MM Burke, ER Townsend and MM Walker Expression of COX-2, mPGE-synthase,, MDR-1 (P-gp) and Bci-x,: a molecular pathway of H pylori-related gastric carcinogenesis G Nardone, A Rocco, D Vaira, S Staibano, A Budillon, F Tatangelo, MG Sciulli, F Perna, G Salvatore, M Di Benedetto, G De Rosa and P Patrignani Phosphorylated KDR is expressed in the neoplastic and stromal elements of human renal tumours and shuttles from cell membrane to nucleus SB Fox, H Turley, M Cheale, C Blazquez, H Roberts, N James, N Cook, A Harris and K Gatter Reduced selenium-binding protein 1 expression is associated with poor outcome in lung adenocarcinomas G Chen, H Wang, CT Miller, DG Thomas, TG Gharib, DE Misek, TJ Giordano, MB Orringer, SM Hanash and DG Beer Linkage of angiotensin 1-converting enzyme gene insertion/deletion polymorphism to the progression of human prostate cancer R Medeiros, A Vasconcelos, S Costa, D Pinto, F Lobo, A Morais, J Oliveira and C Lopes In ovarian neoplasms, BRAF, but not KRAS, mutations are restricted to low-grade serous tumours NLG Sieben, P Macropoulos, GMJM Roemen, SM Kolkman-Uljee, GJ Fleuren, R Houmadi, T Diss, B Warren, M Al Adnani, APM de Goeij, T Krausz, The Cancer Genome Project and AM Flanagan Emmprin, a cell surface inducer of matrix metalloproteinases (MMPs), is expressed in T-cell lymphomas K Nabeshima, J Suzumiya, M Nagano, K Ohshima, BP Toole, K Tamura, H Iwasaki and M Kikuchi Increased expression of Met protein is associated with up-regulation of hypoxia inducible factor-1 (HIF-1) in tumour cells in papillary carcinoma of the thyroid S Scarpino, F Cancellario d’Alena, A Di Napoli, A Pasquini, A Marzullo NINN 5 cn “st avs einstein capsnn situs thas os seething ibsc ash gee saan ehachvgibasoidrpintenaednait boos 352 Molecular analysis of the INK4A/INK4A-ARF gene locus in conventional (central) chondrosarcomas and enchondromas: indication of an important gene for tumour progression HM van Beerendonk, LB Rozeman, AHM Taminiau, R Sciot, JVMG Bovée, A-M Cleton-Jansen and PCW Hogendoorn Vascular endothelial growth factor (VEGF) induces matrix metalloproteinase expression in immortalized chondrocytes T Pufe, V Harde, W Petersen, MB Goldring, B Tillmann and R Mentlein KIT (CD117) is frequently overexpressed in thymic carcinomas but is absent in thymomas C-C Pan, PC-H Chen and H Chiang Western blot analysis of a limited number of cells: a valuable adjunct to proteome analysis of paraffin wax-embedded, alcohol-fixed tissue after laser capture microdissection W Martinet, V Abbeloos, N Van Acker, GRY De Meyer, AG Herman and MM Kockx Announcements Volume Contents Volume 202, Number 4 April 2004 Commentary TIMP-3 and endocrine therapy of breast cancer: an apoptosis connection emerges DR Edwards Original Papers Tissue inhibitors of metalloproteinase expression in human breast cancer: TIMP-3 is associated with adjuvant endocrine therapy success PN Span, RLP Lindberg, P Manders, VCG Tjan-Heijnen, JJTM Heuvel, LVAM Beex and CGJ (F) Sweep Activation of pro-MMP-2 mediated by MT1-MMP in human salivary gland carcinomas: possible regulation of pro-MMP-2 activation by TIMP-2 K Kayano, T Shimada, T Shinomiya, S Nakai, Y Hisa, T Aoki, M Seiki and Y Okada Loss of Smad4 correlates with loss of the invasion suppressor E-cadherin in advanced colorectal carcinomas A Reinacher-Schick, SE Baldus, B Romdhana, S Landsberg, M Zapatka, SP Monig, AH Holscher, HP Dienes, W Schmiegel and I Schwarte-Waldhoff Site-independent prognostic value of chromosome 9q loss in primary gastrointestinal stromal tumours B Gunawan, H-J Schulten, A von Heydebreck, B Schmidt, C Enders, J Hoer, C Langer, P Schuler, CG Schindler, J Kuhigatz and L Fuzesi Gastrointestinal stromal tumours (GISTs) negative for KIT (CD117 antigen) immunoreactivity M Debiec-Rychter, B Wasag, M Stul, I De Wever, AVan Oosterom, A Hagemeijer and R Sciot Inactivating mutation of the pro-apoptotic gene BID in gastric cancer JH Lee, YH Soung, JW Lee, WS Park, SY Kim, YG Cho, CJ Kim, SH Seo, HS Kim, SW Nam, Nu Yoo, SH Lee and JY Lee Cyclin Dl overexpression in thyroid tumours from a radio-contaminated area and its correlation with Pinl and aberrant B-catenin expression M Nakashima, S Meirmanov, Y Naruke, H Kondo, V Saenko, T Rogounovitch, Y Shimizu-Yoshida, N Takamura, H Namba, M Ito, A Abrosimov, E Lushnikov, P Roumiantsev, A Tsyb, S Yamashita and I Sekine Multiparameter DNA flow-sorting demonstrates diploidy and SDHD wild-type gene retention in the sustentacular cell compartment of head and neck paragangliomas: chief cells are the only neoplastic component PB Douwes Dekker, WE Corver, PCW Hogendoorn, AGL van der Mey and CJ Cornelisse Mechanisms underlying the dysfunction of melanocytes in vitiligo epidermis: role of SCF/KIT protein interactions and the downstream effector, MITF-M R Kitamura, K Tsukamoto, K Harada, A Shimizu, S Shimada, T Kobayashi and G Imokawa Gene expression profiles from hypertrophic scar fibroblasts before and after IL-6 stimulation MRK Dasu, HK Hawkins, RE Barrow, H Xue and DN Herndon Comparison of the morphological and biochemical changes in normal human lung fibroblasts and fibroblasts derived from lungs of patients with idiopathic pulmonary fibrosis during FasL-induced apoptosis YP Moodley, P Caterina, AK Scaffidi, NL Misso, JM Papadimitriou, RJ McAnulty, GJ Laurent, PU Thompson and DA Knight Expression of BAFF (BLyS) inT cells infiltrating labial salivary glands from patients with Sjégren’s syndrome F Lavie, C Miceli-Richard, J Quillard, S Roux, P Leclerc and X Mariette Endothelial nitric oxide synthase in the control of osteoblastic mineralizing activity and bone integrity F Afzal, J Polak and L Buttery Letter to the Editor Announcements