Table Of Content

CONTENTS No. 1 JANGARY 1992 EDITORIAL COMMENT Editorial Announcements and Comments GUIDE FOR AUTHORS Guide for Authors (Revised January 1992) Manuscript Submission and Copyright Release Form CRITICAL REVIEW Energy Requirements for Space Flight. Helen W. Lane ARTICLES Biochemical and Molecular Roles of Nutrients Thiazolidine-4-Carboxylate and 2-Phenylthiazolidine-4-Carboxylate are Active as Cysteine Precursors but have No Effect on Growth of a Methionine-Dependent Tumor in Rats. M. Asuncion Recasens, Bernard Possompes, Cécile Astre, Bernard Saint Aubert and Henri Joyeux Regulation of Hepatic Lipogenic Enzyme Gene Expression by Diet Quantity in Rats Fed a Fat-Free, High Carbohydrate Diet. Nobuko Iritani, Naomi Nishimoto, Akihiko Katsurada and Hitomi Fukuda. Wheat Bran and Corn Oil Do Not Influence Proliferation in the Colon of Healthy Rats When Energy Intakes Are Equivalent. K. Malville-Shipan and S. E. Fleming Iron Deficiency Alters DMBA-Induced Tumor Burden and Natural Killer Cell Cytotoxicity in Rats. Amanda T. Spear and Adria Rothman Sherman Nuclear Zinc Uptake and Interactions and Metallothionein Gene Expression are Influenced by Dietary Zinc in Rats. Robert J. Cousins and Linda M. Lee-Ambrose Low Copper Status of Rats Affects Polyunsaturated Fatcy Acid Composition of Brain Phospholipids, Unrelated to Neuropathology. Synthia H-H. Sun and Boyd L. O’Dell Potentiation of Acute Acetaminophen Lethality by Selenium and Vitamin E Deficiency in Mice. FrancisJ . Peterson, NancyJ . Lindemann, Peter H. Duquette and Jordan L. Holtzman. High Dietary Taurine Effects on Feline Tissue Taurine Concentrations and Reproductive Perfor- mance. John A. Sturman and Jeffrey M. Messing Cysteine-Rich Intestinal Protein and Intestinal Methallothionen: An Inverse Relationship as a Con- ceptual Model for Zinc Absorption in Rats. James M. Hempe and Robert J. Cousins lV Human and Clinical Nutrition Plasma Carotenoid Levels in Human Subjects Fed a Low Carotenoid Diet. Cheryl L. Rock, Marian E. Swendseid, Robert A. Jacob and Ralph W. McKee Depressed Immune Response to Tetanus in Children with Vitamin A Deficiency. Richard D. Semba, Muhilal, Alan L. Scott, Gantira Natadisastra, Sopandi Wirasasmita, Lisa Mele, Endi Ridwan, Keith P. West, Jr. and Alfred Sommer Nutrient Metabolism Dietary Calcium Content, Calcium Balance and Mode of Uptake in a Subterranean Mammal, the Damara Mole-Rat. Tammy Pitcher, Rochelle Buffenstein, James D. Keegan, Gopal P. Moodley and Shlomo B-Carotene Uptake and Tissue Distribution in Ferrets (Mustela putorius furo). Eric T. Gugger, Tiffany L. Bierer, Tonja M. Henze, Wendy S. White and John W. Erdman, Jr. .......ce.c.e .ee.e e.ee es Postprandial Lipoprotein Composition in Pigs Fed Diets Differing in Type and Amount of Dietary Fat. Cindie M. Luhman, Terry D. Faidley and Donald C. Beitz Response of Somatomedins (IGF-I and IGF-II) in Lactating Cows to Variations in Dietary Energy and Protein and Treatment with Recombinant n-Methionyl Bovine Somatotropin. Mark A. McGuire, Dale E. Bauman, Margaret A. Miller and Gary F. Hartnell Bone Composition and Histology of Young Growing Rats Fed Diets of Varied Calcium Bioavailability: Spinach, Nonfat Dry Milk, or Calcium Carbonate added to Casein. Catherine A. Peterson, Jo Ann C. ee i ee i iio 5 <b ne i he ae RR he 8 i rns Ko eee ee eee be a hea Free Fatty Acids in Exercising Arabian Horses Fed Two Common Diets. Nicole I. Zimmerman, Steven ]. Wickler, Anne V. Rodiek and Melissa A. Hower Determining Optimal Heat Treatment of Soybeans by Measuring Available Lysine Chemically and Biologically with Rats to Maximize Protein Utilization by Ruminants. Martin A. Faldet, Larry D. Satter and Glen A. Broderick Nutrient Requirements and Interactions Dietary Protein, as Egg Albumen: Effects on Bone Composition, Zinc Bioavailability and Zinc Require- ments of Rats, Assessed by a Modified Broken-Line Model. Janet R. Hunt and LuAnn K. Johnson SYMPOSIUM Starch Digestion: Understanding and Potential for Improvement Starch Digestion: Understanding and Potential for Improvement-Introduction. C. Brent Theurer ... Starch Digestion and Absorption in Nonruminants. Gary M. Gray Starch Hydrolysis by the Ruminal Microflora. Susan F. Kotarski, Ralph D. Waniska and Kerry K. Thurn Regulation of Pancreatic Exocrine Secretion in Ruminants: A Review. Warren James Croom, Jr., Leonard S. Bull and Ian L. Taylor Dietary Influences on Carbohydrases and Small Intestinal Starch Hydrolysis Capacity in Ruminants. David L. Harmon ISSGES AND: OPINIONS IN NUTRITION Assessing the Potential Dietary Impact of Replacing Dietary Fat with Other Macronutrients. Barbara J. Lyle, Kathleen E. McMahon and Patricia A. Kreutler No. 2 FEBRUARY 1992 ARTICLES Biochemical and Molecular Roles of Nutrients Postprandial Lipid Response Following a High Fat Meal in Rats Adapted to Dietary Fiber. Carol L. Redard, Paul A. Davis, Suzette J. Middleton and Barbara O. Schneeman Ethanol-Fed Sprague-Dawley Rats Maintain Normal Levels of Insulin-like Growth Factor I. Daniel J. Smith, Huan Yang, Amy J. Scheff, Stephen A. Ploch and Don S. Schalch Interaction of Carnitine and Propionate with Pyruvate Oxidation by Hepatocytes from Clofibrate-Treated Rats: Importance of Coenzyme A Availability. Eric P. Brass Changes in Pig Serum Lipids, Nutrient Digestibility and Sterol Excretion During Cecal Infusion of Propionate. Kathleen E. Beaulieu and Michael I. McBurney Dietary Soluble Fiber and Cholesterol Affect Serum Cholesterol Concentration, Hepatic Portal Venous Short-Chain Fatty Acid Concentrations and Fecal Sterol Excretion in Rats. Bahram H. Arjmandi, Joungjwa Ahn, Shaheen Nathani and Robert D. Reeves Profile of Short-Chain Fatty Acids and Rectal Proliferation in Rats Fed Sucrose or Cornstarch Diets. Franca Bianchini, Giovanna Caderni, Carmela Magno, Giulio Testolin and Piero Dolara Evaluation of the Preruminant Calf as a Model for the Study of Human Carotenoid Metabolism. Christopher L. Poor, Tiffany L. Bierer, Neal R. Merchen, George C. Fahey, Jr., Michael ee Pe CTE Tee Pe or er Pe ee Various Dietary Fibers Have Different Effects on Lipase-Catalyzed Hydrolysis of Tributyrin in Vitro. Joey A. Hendrick, Tadahiro Tadokoro, Curt Emenhiser, Uwe Nienaber and Owen R. Fennema Rat Colonic Antioxidant Status: Interaction of Dietary Fats with 1,2-Dimethylhydrazine Challenge. Connye Kuratko and Barbara C. Pence Route of Administration of Trytophan and Tyrosine Affects Short-Term Food Intake and Plasma and Brain Amino Acid Concentrations in Rats. Lean Teik Ng and G. Harvey Anderson Atherogenic Diets Enhance Endotoxin-Stimulated Interleukin-1 and Tumor Necrosis Factor Gene Ex- pression in Rabbit Aortae. James C. Fleet, Steven K. Clinton, Robert N. Salomon, Harald Loppnow and Peter Libby Human and Clinical Nutrition The Metabolizable Energy of Diets Differing in Dietary Fat and Fiber Measured in Humans. Carolyn W. Dietary Vitamin C Intake and Concentrations in the Body Fluids and Cells of Male Smokers and Nonsmokers. Mai H. Bui, Alain Sauty, Fabienne Collet and Philippe Leuenberger Long-Term Wheat Germ Intake Beneficially Affects Plasma Lipids and Lipoproteins in Hypercholestero- lemic Human Subjects. Louis Cara, Martine Armand, Patrick Borel, Michele Senft, Henri Portugal, Anne-Marie Pauli, Huguette Lafont and Denis Lairon Nutrient Requirements and Interactions Calcium Carbonate Depresses Iron Bioavailability in Rats More Than Calcium Sulfate or Sodium Carbonate. Tara A. Prather and Dennis D. Miller Nutrient Metabolism Epithelia-Damaging Virus Infections Affect Vitamin A Status in Chickens. Clive E. West, S. Reinder Sijtsma, Ben Kouwenhoven, Jan H.W.M. Rombout and Akke J. van der Zijpp A Mixture of Nucleosides and a Nucleotide Alters Hepatic Energy Metabolism 24 Hours After Hepatectomy in Rabbits. Tetsuya Yamaguchi, Yasutsugu Takada, Yasuyuki Shimahara, Tetsuya Kiuchi, Hiroshi Higashiyama, Keiichiro Mori, Nobuaki Kobayashi, Yoshio Yamaoka and Kazue Vi Replacement of Digestible Wheat Starch by Resistant Cornstarch Alters Splanchnic Metabolism in Rats. Christine Morand, Christian Rémésy, Marie-Anne Levrat and Christian Demigné........ 345 Penicillamine: Pharmacokinetics and Differential Effects on Zinc and Copper Status in Chicks. Junxuan cael ae ie I I oa ees od a ch a a oe Fa aR RS ek Bags ee 355 Adipose Tissue Lipogenesis and Fat Deposition in Leaner Broiler Chickens. Harry D. Griffin, Kunde Co, Dees eter eel lasses CITE 5 x5 ko 5 es a 6 KR os ea sh G a ed eens 363 Adrenalectomy Attenuates the Effect of Chemical Castration on Energy Balance in Rats. D. Ouerghi, S. I I i iiss 5 ieee hd hes he 005 dees oe eee ee a ae cee La 369 Dietary Fat and Cholesterol Modulate the Plasma Lipoprotein Distribution and Production of Pigment or Cholesterol Gallstones in Hamsters. K. C. Hayes, Pramod Khosla, Andrea Kaiser, Vartan Yeghia- siete mil Mees II i 535i Ss denn aoa Re 6 RR CRAPO A PRI WER 374 Amniotic Fluid Composition Responds to Changes in Maternal Dietary Carbohydrate and is Related to Metabolic Status in Term Fetal Rats. Kristine G. Koski and Marjorie A. Fergusson ........... 385 Metabolism of [!4C]- and [32P]Pyridoxal 5’-Phosphate and [?H]Pyridoxal Administered Intravenously to Pigs and Goats. Stephen P. Coburn, J. Dennis Mahuren, Maureen S. Kennedy, Wayne E. Schalten- On a IE OE III og 5 oc CBee ghee Ds as bs kh eee REO BOOK REVIEW Nutrient Additions to Food: Nutritional, Technological and Regulatory Aspects. J. Christopher Bauern- fiend and Paul A. Lachance, eds. Reviewed by Guillermo Arroyave ..............0cceceeuees III, i522 ye de i els aed: Me ee ik oO ees oe cae Pe Os re |i k No. 3 MARCH 1992 BIOGRAPHICAL ARTICLE oases: Vou Amen Poset (1910-1909). 7 By CI onan ee i Sak i edocs cha eee CRITICAL REVIEW Artificial-Rearing Technique: Its Usefulness in Nutrition Research. Mulchand S. Patel and Bhargava K. Hiremagalur i. 6.8 Sie SOW. S ie: Cw Se OR Oe ek 8 ee Boas We UN Ce Se Oe ee Oe Bae: CE eS we Gee ine bee S-e «See oe eee Shee ee Biochemical and Molecular Roles of Nutrients Cysteine Concentration Regulates Cysteine Metabolism to Glutathione, Sulfate and Taurine in Rat Hepatocytes. Martha H. Stipanuk, Relicardo M. Coloso, Rolando A. G. Garcia and Mark F. Banks 420 Zinc Deficiency Alters the Protein Composition of the Membrane Skeleton but not the Extractability or Oligomeric Form of Spectrin in Rat Erythrocyte Membranes. Ross A. Avery and William J. Bettger 428 Changes in Plasma Thyroid Hormone Concentrations in Chronically Food-Restricted Female Rats and Their Offspring During Suckling. Linda V. Oberkotter and Kathleen M. Rasmussen Human and Clinical Nutrition Iron Absorption from Bread in Humans: Inhibiting Effects of Cereal Fiber, Phytate and Inositol Phos- phates with Different Numbers of Phosphate Groups. Mats Brune, Lena Rossander-Hultén, Leif Hallberg, Ann Gleerup and Ann-Sofie Sandberg Purification and Partial Characterization of Cellular Retinol-Binding Protein, Type Two, from Human Small Intestine. Sanae Inagami and David E. Ong VLDL Apolipoprotein B-100, a Potential Indicator of the Isotopic Labeling of the Hepatic Protein Synthetic Precursor Pool in Humans: Studies with Multiple Stable Isotopically Labeled Amino Acids. Peter J. Reeds, David L. Hachey, Bruce W. Patterson, Kathleen J. Motil and Peter D. Klein A Comparison of the Effects of Beef, Chicken and Fish Protein on Satiety and Amino Acid Profiles in Lean Male Subjects. Anthony M. Uhe, Greg R. Collier and Kerin O’Dea Nutrient Metabolism Bile Acid Metabolism in Rats Fed Two Levels of Corn Oil and Brans of Oat, Rye and Barley and Sugar Beet Fiber. Daniel D. Gallaher, Patricia L. Locket and Cynthia M. Gallaher Excess Levels of Cysteine and Homocysteine Induce Tibial Dyschondroplasia in Broiler Chicks. Michael W. Orth, Yisheng Bai, Ibrahim H. Zeytun and Mark E. Cook Porcine Skeletal Muscle Myofibrillar Protein Synthesis is Stimulated by Ractopamine. Olayiwola Adeola, Ronald O. Ball and Leslie G. Young Dynamic and Static Phases of Severe Dietary Obesity in Sheep: Food Intakes, Endocrinology and Carcass and Organ Chemical Composition. Joseph P. McCann, Emmett N. Bergman and Donald H. Beermann Colonic Absorption of Menaquinone-4 and Menaquinone-9 in Rats. Teruhisa Ichihashi, Yasushi Takagishi, Kiyohisa Uchida and Hideo Yamada Cholesterol-Lowering in Hamsters Fed Rice Bran at Various Levels, Defatted Rice Bran and Rice Bran Oil. Talwinder S. Kahlon, Faye I. Chow, Robert N. Sayre and Antoinette A. Betschart Excessive Cholesterolemic Response in Analbuminemic Rats Fed a Cholesterol-Rich Diet Containing Casein. Xizhong Zhang, Jaap A. Joles, Hein A. Koomans, Arie Van Tol and Anton C. Beynen. Feeding Status Affects In Vivo Prosucrase-Isomaltase Processing in Rat Jejunum. Mary A. Dudley, Buford L. Nichols, Judy Rosenberger, ]. Scott Perkinson and Peter J. Reeds Nutrient Requirements and Interactions Biotin in Human Milk: Methods, Location and Chemical Form. Donald M. Mock, Nell I. Mock and Susan E. Langbehn Secretory Patterns of Biotin in Human Milk. Donald M. Mock, Nell I. Mock and Jon A. Dankle. Taurine Balance is Different in Cats Fed Purified and Commercial Diets. Mary A. Hickman, Quinton R. Rogers and James G. Morris Reduction of Intestinal Viscosity through Manipulation of Dietary Rye and Pentosanase Concentration is Effected through Changes in the Carbohydrate Composition of the Intestinal Aqueous Phase and Results in Improved Growth Rate and Food Conversion Efficiency of Broiler Chicks. Michael R. Bedford and Henry L. Classen Marginal Zinc Deficiency has no Effect on Primary or Challenge Infections in Mice with Helig- mosomoides polygyrus (Nematoda). Tracy M. Minkus, Kristine G. Koski and Marilyn E. Scott . Interaction of Calcium and Phosphate Decreases Ileal Magnesium Solubility and Apparent Magnesium Absorption in Rats. Elizabeth J. Brink, Anton C. Beynen, Pieter R. Dekker, Emerentia C. H. van Beresteijn and Roelof van der Meer LETTER TO THE EDITOR Summary of 1991 Meeting of International Vitamin A Consultative Group Now Available. Laurie Lindsay Aomari Erratum Announcements No. 3s MARCH 1992 AIN 1991 SYMPOSIGM PROCEEDINGS SYMPOSIA Symposium: History of Nutritional Immunology History of Nutritional Immunology: Introduction and Overview William R. Beisel Protein-Energy Malnutrition and Immunological Responses Ranjit Kumar Chandra Vitamins and Immunity Adrianne Bendich Zinc, Copper and Iron Nutriture and Immunity Adria R. Sherman Dietary Lipids and Immune Function Patricia A. Maki and Paul M. Newberne Symposium: Enhancement of Biological Activity by Conjugation Reactions Enhancement of Biological Activity by Conjugation Reactions James A. Olson, Richard C. Moon, M. W. Anders, Catherine Fenselau and Barry Shane Symposium: Regulation of Antioxidant Enzymes Regulation of Antioxidant Enzymes Edward D. Harris OxyR: A Regulator of Antioxidant Genes Gisela Storz and Louis A. Tartaglia Oxidants and Antioxidants in Development and Differentiation R. G. Allen and V. S. Venkatraj. . Copper as a Cofactor and Regulator of Copper, Zinc Superoxide Dismutase Edward D. Harris.... Symposium: Current Concepts of Calcium Absorption Current Concepts of Calcium Absorption: An Overview Felix Bronner Intestinal Calcium Absorption: Calcium Entry Curtis S. Fullmer Facilitated Diffusion of Calciura across the Rat Intestinal Epithelial Cell Vesicular Calcium Transport in Chick Intestine Jlka Nemere Intestinal Calcium Transport and Calcium Extrusion Processes at the Basolateral Membrane Robert H. Wasserman, John S. Chandler, Sharon A. Meyer, Christiana A. Smith, Marie E. Brindak, Curtis S. Fullmer, John T. Penniston and Rajiv Kumar Paracellular Calciujm Transport Across the Small Intestine Ulrich Karbach Molecular Aspects of the Calbindins Sylvia Christakos, Rajbir Gill, Sooja Lee and Hui Li The Use of Pharmacologic Agents to Study Mechanisms of Intestinal Calcium Transport Murray J. Favus and Vrishali Tembe Symposium: Application of Models to Determination of Nutrient Requirements Application of Models to the Determination of Nutrient Requirements: An Overview Stephen P. Introduction to Modeling Michael H. Green Resources for Getting Started in Modeling Jerry C. Collins Application of Models to Determination of Nutrient Requirements: Experimental Techniques Employing Tracers C. F. Ramberg, Jr., C. R. Krishnamurti, D. Peter, J. E. Wolff and R. C. Boston The Determination of Nutritional Requirements: Mathematical Modeling of Nutrient-Response Curves L. Preston Mercer Development of a Model for Selenite Metabolism in Humans Blossom H. Patterson and Loren A. Zech Symposium: Nutrition, Immunomodulation and AIDS Nutrition, Immunomodulation and AIDS: An Overview Ronald Ross Watson Potential of Diet Therapy on Murine AIDS Gabriel Fernandes, Vikram Tomar, Mohan N. Venkatraman and Jaya T. Venkatraman Nutritional Effects and Support in the Patient with Acquired Immunodeficiency Syndrome Donald P. A Preliminary Trial of Beta-Carotene in Subjects Infected with the Human Immunodeficiency Vi- rus Harinder S. Garewal, Neil M. Ampel, Ronald R. Watson, Rao H. Prabhala and Cynthia L. Dols Role of Alcohol Abuse in Nutritional Immunosuppression Bernhard Watzl and Ronald R. Watson Immunosuppression and Alteration of Resistance to Pulmonary Tuberculosis in Guinea Pigs by Protein Undernutrition David N. McMurray and Rebecca A. Bartow LP-BMS5, a Murine Model of Acquired Immunodeficiency Syndrome: Role of Cocaine, Morphine, Alcohol and Carotenoids in Nutritional Immunomodulation Ronald Ross Watson The Role of the Cytokines, Interferon Alpha and Tumor Necrosis Factor in the Hypertriglyceridemia and Wasting of AIDS Carl Grunfeld and Kenneth R. Feingold Nutrition and Immunoregulation. Significance for Host Resistance to Tumors and Infectious Diseases in Humans and Rodents Ranjit Kumar Chandra Symposium: Nutrition and Exercise Nutrition and Exercise Introduction and Overview Lester Packer and Vishwa N. Singh A Current Perspective on Nutrition and Exercise Vishwa N. Singh Exercise, Oxidative Damage and Effects of Antioxidant Manipulation Eric H. Witt, Abraham Z. Reznick, Christine A. Viguie, Pamela Starke-Reed and Lester Packer Exercise and Food Restriction in Rats John O. Holloszy Nutrition at High Altitude Irene M. Simon-Schnass Exercise and Iron Status Connie M. Weaver and Sujatha Rajaram Carbohydrate Supplementation during Exercise Edward F. Coyle Exercise, Nutrition and Aging William ]. Evans CONFERENCES Conference: In Vitro Approaches to Understanding Growth and Development The Use of Avian Epiphyseal Chondrocytes for In Vitro Studies of Skeletal Metabolism Roland M. Leach and Gaston E. Rosselot In Vitro Systems for the Analysis of the Development of Adipose Tissue in Domestic Animals Timothy G. Ramsay, S. V. Rao and C. K. Wolverton Cell Culture as a Tool for the Study of Poultry Skeletal Muscle Development Douglas C. McFarland Conference: Hepatic Metabolism of Organic Acids in Ruminants Hepatic Metabolism of Organic Acids in Ruminants: Introduction Donald C. Beitz Metabolism of Long Chain Fatty Acids by Ruminant Liver Roy S. Emery, James S. Liesman and Thomas H. Herdt Ruminant Hepatic Metabolism of Volatile Fatty Acids, Lactate and Pyruvate Louis E. Armentano. Metabolic Heterogeneity of Hepatocytes across the Liver Acinus Norbert R. Katz Metabolism of Nitrogenous Compounds by Ruminant Liver Christopher K. Reynolds MINISYMPOSIUM Minisymposium: Effect of Partitioning Agents on Nutrient Requirements Impact of Somatotropins on Nutrient Requirements in Domestic Animals Robert J. Collier, John L. Vicini, Christopher D. Knight, Carol L. McLaughlin and Clifton A. Baile No. 4 APRIL 1992 BIOGRAPHICAL ARTICLE Kendall Willard King (1926-1990). George Edwin Bunce ARTICLES Biochemical and Molecular Roles of Nutrients Regulation of Hepatic Transthyretin Messenger RNA Levels during Moderate Protein and Food Re- striction in Rats. Béatrice Le Moullac, Patricia Gouacixe and Fanny Bleiberg-Daniel Collagen Synthesis in Human Skin Fibroblasts is Stimulated by a Stable Form of Ascorbate, 2-O-a-D- Glucopyranosyl-L-Ascorbic Acid. Jtaru Yamamoto, Norio Muto, Kouki Murakami and Jun-Ichi Akiyama Comparison of Constant Infusion and Flooding Dose Techniques to Measure Muscle Protein Synthesis Rate in Dogs. Farook Jahoor, Xiao-Jun Zhang, Hidefumi Baba, Yoichi Sakurai and Robert R. Wolfe Folate Deficiency Alone Does Not Produce Neural Tube Defects in Mice. Mary K. Heid, Nathan D. Bills, Steven H. Hinrichs and Andrew J. Clifford Dietary Glucose and Fat Attenuate Effects of Adrenalectomy on Energy Balance in ob/ob Mice. /in-Soon Kang, James D. Pilkington, Deborah Ferguson, Hye-Kyung Kim and Dale R. Romsos The Influence of Dietary Fiber on Proliferation of Intestinal Mucosal Cells in Miniature Swine May Not Be Mediated Primarily by Fermentation. S. E. Fleming, M. D. Fitch and S. De Vries Age- and Dietary Fat-Related Effects on Biliary Lipids and Cholesterol Gallstone Formation in African Green Monkeys. Martin W. Scobey, Mary S. Wolfe and Lawrence L. Rudel Human and Clinical Nutrition Shifting from a Conventional Diet to an Uncooked Vegan Diet Reversibly Alters Fecal Hydrolytic Activities in Humans. Wen Hua Ling and Osmo Hdnninen Nutrient Metabolism Hyperresponsiveness to Dietary Cholesterol in Inbred Rabbits Is Not Associated with Enhanced Reduction in Binding of B-VLDL to Liver Membranes. G. W. Meijer, A. C. Beynen, M. R. Lovati, C. Manzoni, L.F.M. Van Zutphen and C. R. Sirtori Cytochrome b;/Cytochrome bs Reductase Complex in Rat Liver Microsomes has NADH-Linked Aqua- cobalamin Reductase Activity. Fumio Watanabe, Yoshihisa Nakano, Hisako Saido, Yoshiyuki Tamura and Hiroyuki Yamanaka The Mechanisms of Nonheme Iron Uptake Determined in IEC-6 Rat Intestinal Cells. Gary M. Nichols, Allen R. Pearce, Xavier Alverez, Nancy K. Bibb, Khanh Y. Nichols, Charlotte B. Alfred and Jonathan Comparative Metabolism of Phylloquinone and Menaquinone-9 in Rat Liver. Birgit H. Will and J. W. L-Carnitine Administration and Withdrawal Affect Plasma and Hepatic Carnitine Concentrations, Plasma Lipid and Lipoprotein Composition, and In Vitro Hepatic Lipogenesis from Labeled Mevalonate and Oleate in Normal Rabbits. Frank P. Bell, Thomas J. Vidmar and Thomas L. Raymond Changes in Liver Structure and Function after Short-Term and Long-Term Treatment of Rats with Dehydroepiandrosterone. Monica Bellei, Daniela Battelli, Claudio Fornieri, Giuseppe Mori, Um- berto Muscatello, Henry Lardy and Valentina Bobyleva Incorporation of 3H-Label from Folic Acid is Tissue-Dependent in Folate-Deficient Rats. Bernard H. Eisenga, Timothy D. Collins and Kenneth E. McMartin Nutrient Requirements and Interactions Long-Term Folate Deficiency Alters Folate Content and Distribution Differentially in Rat Tis- sues. Gregorio Varela-Moreiras and Jacob Selhub Voluntary Intake, Milk Production and Plasma Metabolites in Nursing Mares Fed Two Different Diets. Michel Doreau, Sylviane Boulot, Dominique Bauchart, Jean-Pierre Barlet and William Martin-Rosset Reexamination of Protein Requirements in Adult Male Humans by End-Product Measurements of Leucine and Lysine Metabolism. Gordon A. Zello, Joseph Telch, Ruth Clarke, Ronald O. Ball and Paul B. Pencharz Dietary (n-3) Fatty Acid and Vitamin E Interactions in Rats: Effects on Vitamin E Status, Immune Cell Prostaglandin E Production and Primary Antibody Response. Kevin L. Fritsche, Nancy A. Cassity and Shu-Cai Huang Dietary Protein Source (Soybean vs. Casein) and Taurine Status Affect Kinetics of the Enterohepatic Circulation of Taurocholic Acid in Cats. Mary A. Hickman, Michael L. Bruss, James G. Morris and Quinton R. Rogers Pyridoxine-5’-B-D-Glucoside Affects the Metabolic Utilization of Pyridoxine in Rats. Joyce A. Gilbert and Jesse F. Gregory III Molybdenum Requirement of Female Rats. Xingjia Wang, Donald Oberleas, Meiling T. Yang and Shiang P. Yang Announcements ARTICLES Biochemical and Molecular Roles of Nutrients Lymph Chylomicron Composition and Size are Modified by Level of Intestinally Infused Cholesterol and Triglyceride Source in Rats. Theodore J. Kalogeris and Jon A. Story Energy Restriction and Testosterone Implants Alter Ornithine Decarboxylase Gene Expression in Kidney of Female Rats. Myunggi Baik, Robert L. Harrold, Chang B. Choi, William D. Slanger, Chang K. Sung and Chung S. Park Retinoid Repletion of Vitamin A-Deficient Mice Restores IgG Responses. Tae Yon Chun, Julie A. Carman and Colleen E. Hayes Barley Diets with Different Fat Sources have Hypocholesterolemic Effects in Chicks. Virginia M. Martinez, Rosemary K. Newman and C. Walter Newman Dietary Fish Oil Modulates the Alkaline Phosphatase Activity and not the Fluidity of Rat Intestinal Microvillus Membrane. Rachel Wahnon, Uri Cogan and Shoshana Mokady xii Studies with Compounds that Compete with Tryptophan Binding to Rat Hepatic Nuclei. Herschel Sidransky, Ethel Verney, James W. Cosgrove and Arnold M. Schwartz Incorporation of [?H]|Proline into Collagen and Other Proteins in Rats Fed Diets with Various Zinc Concentrations. Christopher J. Bates and Peter H. Evans Community and International Nutrition The Association between Wasting and Stunting: An International Perspective. Cesar G. Victora... Human and Clinical Nutrition Cellular Ascorbate Depletion in Healthy Men. Robert A. Jacob, Frederick S. Pianalto and Robert E. Calcium Metabolism in Postmenopausal Osteoporotic Women is Determined by Dietary Calcium and Coffee Intake. Claus Hasling, Karen Sondergaard, Peder Charles and Leif Mosekilde Nutrient Metabolism Net Renal Arginine Flux in Rats is Not Affected By Dietary Arginine or Dietary Protein Intake. Srinivas N. Dhanakoti, John T. Brosnan, Margaret E. Brosnan and Gene R. Herzberg Urinary Taurine Excretion as a Function of Taurine Intake in Adult Cats. Eric N. Glass, Jack Odle and David H. Baker Changes in Liver Concentration of N-Acetylglutamate and Ornithine are Involved in Regulating Urea Synthesis in Rats Treated with Thyroid Hormone. Kazutoshi Hayase, Goro Yonekawa and Akira Yoshida Developmental Changes in Glucose and Butyrate Metabolism by Isolated Sheep Ruminal Cells. R. L. Baldwin VI and B. W. Jesse Methionine Intake in Rainbow Trout (Oncorhynchus mykiss), Relationship to Cataract Formation and the Metabolism of Methionine. Colin B. Cowey, C. Young Cho, Jacob G. Sivak, Judy A. Weerheim and Darrin D. Stuart Secretion of Lipoprotein Cholesterol by Perfused Livers from Rabbits Hypo- or Hyperresponsive to Dietary Cholesterol: Greater Dietary Cholesterol-Induced Secretion in Hyperresponsive Rabbits. G. W. Meijer, ].G.P. Van Der Palen, M.].H. Geelen, A. Versluis, L.F.M. Van Zutphen and A. C. Beynen Nutrient Requirements and Interactions Type of Dietary Carbohydrate Affects Thyroid Hormone Deiodination in Iron-Deificient Rats. Scott M. Smith and Henry C. Lukaski Protein Insufficiency Aggravates the Enhanced Lipid Peroxidation and Reduced Activities of Antiox- idative Enzymes in Rats Fed Diets High In Polyunsaturated Fat. Ching-Jang Huang and Ming-Ling Soybean Protein Isolate and Soybean Lectin Inhibit Iron Absorption in Rats. Sanae Hisayasu, Hideo Orimo, Setsuko Migita, Yuki Ikeda, Kuminko Satoh, Setsuko Shinjo (Kanda), Yukihiko Hirai and Yoshio Yoshino i Announcements No. 6 JUNE 1992 ARTICLES Biochemical and Molecular Roles of Nutrients Copper Deficiency Alters Plasma Pool Size, Percent Composition and Concentration of Lipoprotein Components in Rats. Abdullah A. Al-Othman, Fumiko Rosenstein and Kai Y. Lei