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ArtificialIntelligenceinMedicine21(2001)1–25 The Fuzzy Revolution: Goodbye to the Aristotelian Weltanschauung Kazem Sadegh-Zadeh* TheoryofMedicineDepartment,UniversityofMu¨nsterMedicalInstitutions, WaldeyerSt.27,48149Mu¨nster,Germany Accepted1August2000 Because of its unorthodoxy, it has been and will continue to be controversial for some time.Eventually,though,thetheoryoffuzzysetsislikelytoberecognizedasanaturaldevelopment in the evolution of scientific thinking. In retrospect, the skepticism about its usefulness will be viewedasamanifestationofthehumanattachmenttotraditionandresistancetoinnovation([91], p.421). 1. Dear Professor Zadeh Themedicalartificialintelligencecommunitycongratulatesyouonyour80thbirthday on4February2001.Onbehalfofallpatientsandnon-patientswhoare,orwillinthefuture be,enjoyingthemedicalfruitsofyourwork,wewouldliketothankyouforinitiatingand advancing The Fuzzy Revolution in science, technology, and society. Medicine has been among the privileged areas to early recognize this revolution and to embrace the fuzzy theory in parallel withthe seminal Mamdani and Assilian application in the engineering sciences and technology [35,36] (see, e.g. [2,30,73,74]).1 The tempo, the scope, and the quantity of medical fuzzy research and technology have exponentially increased in the meantime.Thereisnomedicalsubdomainleftoutsidethisacceleratingfuzzystreamtoday. This advancement of medical thinking and practice we owe to your foresight already *Tel.:(cid:135)49-251-83-55287;fax:(cid:135)49-251-83-55339. E-mailaddress:[email protected](K.Sadegh-Zadeh). 1Inthepresentcontext,theterm‘fuzzytheory’isusedasaunifyinglabelforthetheoryoffuzzysets(cid:135)theory of linguistic variables and hedges(cid:135)fuzzylogic(cid:135)concomitant conceptual frameworks and theories based on these foundations. Although the term ‘fuzziness theory’ would be preferable, it may not be generally acceptable. 0933-3657/01/$–seefrontmatter#2001ElsevierScienceB.V.Allrightsreserved. PII:S0933-3657(00)00071-3 2 K.Sadegh-Zadeh/ArtificialIntelligenceinMedicine21(2001)1–25 communicatedin1962,3yearsbeforetheexplicitinceptionofyourfuzzytheoryin1965 [77,78]: Infact,thereisafairlywidegapbetweenwhatmightberegardedas‘animate’system theoristsand‘inanimate’systemtheoristsatthepresenttime,anditisnotatallcertain thatthisgapwillbenarrowed,muchlessclosed, inthenearfuture.Therearesome who feel this gap reflects the fundamental inadequacy of the conventional mathe- matics — the mathematics of precisely-defined points, functions, sets, probability measures,etc.—forcopingwiththeanalysisofbiologicalsystems,andthattodeal effectively with such systems, which are generally orders of magnitudes more complexthanman-madesystems,weneedaradicallydifferentkindofmathematics, the mathematics of fuzzy or cloudy quantities which are not described in terms of probability distributions... ([76], p. 857). Sincethepatientasthesubjectofmedicineisananimatesystem,medicalprofessionals inresearchandpracticeareindeedanimatesystemtheoristsand‘‘needaradicallydifferent kind of mathematics...’’ you have created. The prospect abovewas concretized later by explicit demonstrations such as ‘‘Biological application of the theory of fuzzy sets and systems’’ [79], and by numerous encouragements and hints we have received from you regularly in your ground-breaking publications. Unfortunately, initial misunderstandings on the nature of fuzzy theory disseminated by some scholars such as Rudolf Kalman, WilliamKahanandMyronTribushavebeenamajorobstacletotheawarenessinmedicine that this theory is no mere addition to the traditional methods and methodologies, but a novelWeltanschauungsteadilyandquietlybringingaboutaradicalrevolutionofscientific thinking,reasoningandconceptandtheoryformationontheonehand,andoftechnology andsociety,ontheother.Incontrasttoineffectiveattemptsinthepastbydifferentscholars to criticize or refute one or the other of the Aristotelian principles in isolation, it successfully terminates the whole Aristotelian paradigm that has been reigning over scientificreasoningandhumancultureforthelast2300years.Inthissense,itrepresentsa unique, unprecedented example of Thomas Kuhn’s account of scientific change by paradigm shift [33]. The all-embracing paradigm shift caused by fuzzy theory that we are excitedly witnessing is too far-reaching to allow any of the Aristotelian foundations to survive. It,thus,exercisesanunfuzzybreakwithalong-standinganddeeplyentrenchedtradition. Toassesstheimpactofthisdepartureonhumancultureandcivilizationingeneral,andon medicine in particular, we will have to carefully consider what in this process is being replaced with what. 2. Goodbye to the Aristotelian Weltanschauung The Polish physician Ludwik Fleck published in 1935 a remarkable book in German entitled Entstehung und Entwicklung einer wissenschaftlichen Tatsache, i.e. genesis and developmentofascientificfact,whichwasneglectedbyhiscontemporaries[19,20].Like Karl Popper’s influential monograph on ‘The Logic ofScientific Discovery’ launched in thesameyear[40],theViennaCircle’slogical-empiricistviewonthenatureofscientific K.Sadegh-Zadeh/ArtificialIntelligenceinMedicine21(2001)1–25 3 knowledge was its target.2 Unlike Popper and by a detailed historical-philosophical analysis of research on syphilis, however, Fleck developed in his book a fascinating, original,relativisticepistemologyaccordingtowhichscientificknowledgeisconstructed bya‘thoughtcollective’,whichwewouldcall‘scientificcommunity’today,actinginthe realm of aparticular‘thought style’. Viewed from within different thought styles, things look different [19–22]. As Thomas Kuhn briefly acknowledges in the foreword to his acclaimed book on the structureofscientificrevolutions([33],pp.vi–vii),Fleck’swidelyunrecognizedpublica- tionhasservedasthemainsourceofinspirationofhisownparadigm-shifttheory.Kuhn’s paradigmsareinfactFleck’sthoughtstyles.SinceKuhnhadusedhisnotionofaparadigm extremelylooselyandreceivedvarious,incisivecriticisms[37,64],helatersubstitutedfor itthenotionofa‘disciplinarymatrix’[34].Thedisciplinarymatrixinaparticularscientific areaisinessencethesetofsharedbasicrules,methods,andbeliefswhichunderlietheory formation and knowledge acquisition in this area. Althoughalloftheseconceptsarestilltoovagueandinadequatetobeveryuseful,3we may,nevertheless,learnfromthesestudiesthatincontrasttoouraccustomedviewsonthe development of science and scientific knowledge, this very development is not a cumu- lativeprocess.Sciencedoesnotprogresscontinuouslyandbyaccumulatingknowledge.It does notadd toanantecedentknowledge ortheory T asubsequent knowledge ortheory i T ofthesametypesuchthatonecouldreasonablyconsiderscienceastheopen,ordered i(cid:135)1 seriesofrelatedtheoriesT ;T ;...;T .Scientificideas,theories,andworldviewsevolve 1 2 i(cid:135)1 discontinuouslyinthatabodyofknowledgeortheoryT,whichisheldoveraparticular i period of time, is dislodged by another body of knowledge or theory T because the j disciplinary matrix within which the former theory T had grown, changes to another i disciplinary matrix which gives rise to the new theory, T, that is incompatible and j incommensurable with its predecessor T. For example, the Hippocratic and Galenic i humoral pathology rooted in the pre-anatomical era of antiquity considered illness as an imbalanceoffourhumorsinthebody,i.e.bile,phlegm,bloodandurine,andlasteduntilthe eighteenth century. After Andreas Vesalius’ anatomy, De Humanis Corporis Fabrica (1543),andthethen-emergingearlyempiricismconceptualizedbyFrancisBaconandJohn Lockehadmadeanovel,empirical-anatomicaldisciplinarymatrixavailablewithinwhich illnessappearedtohavesomethingtodowithsolidpartsofthebody,humoralpathology wasreplacedwiththelocalizedpathologyofDeSedibusetCausisMorborum(1761)by GiovanniBattistaMorgagni.Bytheendoftheeighteenthcentury,itwascomplementedby 2TheViennaCircle(1923–1936)wasasmallgroupofphilosophers,naturalscientists,socialscientists,and mathematicianssuchasMoritzSchlick,OttoNeurath,RudolfCarnap,HansHahn,FriedrichWaismann,Herbert Feigl, Karl Menger, Kurt Go¨del and a few additional ones. It constituted the germ cell of a philosophical movementdubbed‘logicalempiricism’propagatingtheviewthatknowledgeoftheworldisperceptionplus logic(cf.[9,32]).LudwikFleck(1896–1961)was a Polishphysicianandmicrobiologistandlivedin Lwow, Poland. In June 1941, hewas deported to the Jewish ghetto in his city and later, in December 1943, to the concentration camp Buchenwald in Germany to do research on typhus serum. He survived and returned to Polandin 1945andemigratedto Israel in 1957.He is widelyrecognizedtoday as the founderof thesocial constructionisttheoryofscience.Foracomprehensiveaccountofhislifeandwork,see[11]. 3Foranextensiveandinspiringexplicationandelucidation,see[65]. 4 K.Sadegh-Zadeh/ArtificialIntelligenceinMedicine21(2001)1–25 Francois Xavier Bichat’s tissue pathology. After the development of the microscope had enabled Theodor Schwann to discover the animal cell around 1838, localized pathology wasreplacedwithRudolfVirchow’scellularpathology(1858),whichconsidereddiseases ascellularchangesanddisorders.Withsomealterationsandadditions,thisviewhasbeen dominating medicine since. We are currently witnessing the emergence of a competing molecular pathology, e.g. genomics and pathobiochemistry, which explains and treats diseases as molecular processes in the body. Maybe our descendants will encounter quantum pathology or something like that in the near future [59]. Inthecourseofsuchadiscontinuousevolution,aprecedingtheoryT isabandonedanda i subsequenttheoryT isusedinstead.ThisissonotbecauseT wasdemonstratedtobefalse j i or T was shown to be true, but because concepts and methods have changed which are j employed in constructing and acquiring knowledge, i.e. theory T in the present case. j Our examples above and also comparable cases dealt with in the literature, such as Newtonian mechanics or Einstein’s theory of relativity and the like, exemplify only particulartheoriesandsingularpiecesofknowledge,eachofwhichemergesfromwithina specificdisciplinarymatrix.Interestingly,however,therearealsodisciplinarymatrixesof highergenerality,suchastheconceptoftwo-valuedness,whichareresponsiblenotonlyfor the emergence of individual theories, but for the very mode of scientific thinking and inquiry in all fields. At the highest level of generality we presently encounter, to our surprise, a particular disciplinary matrix which has been nourishing all sciences and theoriesforthelast2300years,i.e.theAristoteliandisciplinarymatrix,becauseitcontains thetwo-valued,classicallogicwithwhichresearchersreasonanddefendtheirwork.What is being eradicated by fuzzy theory is just this universal disciplinary matrix. One may, therefore, easily imagine what may happen when this deeply entrenched Aristotelian thought style will be replaced with the thought style of fuzzy theory. No conceptual structure, method, knowledge, theory, and research program will survivewhich does not accord with the new disciplinary matrix. The foundations of the Aristotelian disciplinary matrix had been laid by Aristotle himselfinhisMetaphysics,Organon,andDeInterpretatione.Theywouldconstituteover more than two millennia the basic principles of classical reasoning in science, mathe- matics, philosophy, religion, politics, law, ethics, and all other areas. The following six passages A–F stated in the Metaphysics, together with a seventh concept, G, a modern derivative from his logic, sufficiently represent these principles: (A)Thiswillbeplainifwefirstdefinetruthandfalsehood.Tosaythatwhatisisnot,or that what is not is, is false; butto say that what is is, and what is not is not, is true (The Metaphysics, Book IV, 1011 b 26–27) [3]. (B) By demonstrativeI mean..., e.g. ‘‘everythingmustbe either affirmed or denied’’, and ‘‘it is impossible at once to be and not to be’’ (ibid., B III, 996 b 27–30). (C)...thatisthemostcertainofallprinciples.Letusnextstatewhatthisprincipleis.‘‘It isimpossibleforthesameattributeatoncetobelongandnottobelongtothesamething and in the same relation’’ (ibid, B IV, 1005 b 19–23). (D) Nor indeed can there be any intermediate between contrary statements, but of onethingwe musteither assert ordenyonething, whateverit maybe(ibid., B IV, 1011 23–24). K.Sadegh-Zadeh/ArtificialIntelligenceinMedicine21(2001)1–25 5 (E) Further, an intermediate between contraries will be intermediate either as grey is betweenblackandwhite,oras‘‘neithermannorhorse’’isbetweenmanandhorse(ibid.,B IV,1011b29–32)....Again,therewillalsobeanintermediateinallclassesinwhichthe negation of a term implies the contrary assertion; e.g. among numbers there will be a numberwhichisneitheroddnornot-odd.Butthisisimpossible...(ibid.,BIV,1012a8–11). (F) Again, unless it is maintained merely for argument’s sake, the intermediate must existbesideallcontraryterms;sothatonewillsaywhatisneithertruenorfalse.Anditwill existbesidewhatisandwhatisnot;sothattherewillbeaformofchangebesidegeneration and destruction (ibid., B IV, 1012 a 5–8). (G)Asetofpremiseslogicallyimpliesaconclusionif,andonlyif,wheneverthepremisesare truetheconclusionistrue.PassageAisthecorrespondenceconceptoftruthprovidingthebasis fortherest,andbeingtherootofthecorrespondencetheoryoftruthandofTarskisemanticsof classical,two-valuedlogic.PassageBistheprincipleoftwo-valuedness.Thesecondhalfof thispassageandpassageCarealternativeformulationsofthelawofnon-contradiction,which saysthatastatementoftheforma^:aiscontradictory,nevertrueandshouldthereforebe rejected,:(a^:a).PassagesBandDgivedifferentformsofthelawofexcludedmiddle, a_:a,whichsaythatsuchastatementisatautologyandalwaystrue. InpassageE,two-valuednessisdefendedonceagainbecauseotherwiseonewouldhave tosupposethatthereare—sic!—classeswithoutsharpboundariesbetweenmembersand non-members. But this is, Aristotle says, impossible. So he may be viewed as the progenitor of Georg Cantor’s two-valued set theory. PassageFinthesameveinrejectstheviewthattheremaybeanintermediatebetweenbeing andnonbeing.ThiscommonlyheldAristotelianontologywillbereferredtobelowasthe doctrineofcrispexistence.Allofussharethisontologicaldoctrine,sinceallofusbelieveand assertthat‘everythingisorisnot,thereisnointermediatebetweenbeingandnonbeing’. The closing definition, G, of the concept of logical implication, consequence, or inference, has emergedfrom the modern reconstruction, completion, and axiomatization of Aristotelian logic in the 19 and 20th centuries by Bernhard Bolzano, Gottlob Frege, BertrandRussellandothers.Itrepresentsthebasicconceptofthetheoryofdeductionand proof underlying all classical mathematics, science, and technology. Therehavebeenvariousattemptsinthepasttoinvalidateoneoranotheroftheprinciples or concepts A–G above in isolation. None of them has attained general acceptance, however.Forexample,many-valuedlogicsruncountertotheprincipleoftwo-valuedness. Intuitionisticlogicdoesnotacceptthelawofexcludedmiddle.Paraconsistentlogicsreject the law of non-contradiction.4 4Paraconsistentlogicsareinconsistencytolerantsystemsoflogicwhichdonotcontainaprincipleofnon- contradiction.Theyoriginatedaround1910withtheRussianphysicianNikolajA.Vasiliev(1880–1940),whoat thebeginningofthe 20thcenturytaughtphilosophy attheUniversityofKazan,Russia.Inspired byNikolaj Lobachevski’snon-EuclideangeometriesinwhichtheEuclideanparallelpostulateisnotvalid,heattemptedto constructnew,‘ImaginaryLogics’bydiscardingsomeofthebasiclawsofclassicallogic[4,70,71].Theselogics would enable us to study a large class of ‘imaginary worlds’ that are impossible to classical logic, but nevertheless,quitewell imaginable. After Stanislaw Jaskowski’sinterlude[29],specificresearchin thisnew field of non-classical logics was initiated by the significant work of the Brazilian logician and philosopher NewtonC.A.daCosta[12,13].Theterm‘paraconsistentlogic’wascoinedbythePeruvianphilosopherF.Miro Quesadain1976.Foracomprehensiveaccountofthesubject,see[25,41,50]. 6 K.Sadegh-Zadeh/ArtificialIntelligenceinMedicine21(2001)1–25 However,thelethalcollapseofthe Aristoteliandisciplinarymatrix iscausedbyfuzzy theory in that all fundamental principles and concepts A–G above are being removed at once in the following way. The treatment of truth in fuzzy theory as a many-valued linguistic variable with a colorfulandinvigoratingtermsetsuchas{true,nottrue,verytrue,completelytrue,more or less true, fairly true, false, very false,..., etc....}, and the treatment of these terms as labelsoffuzzysetsovertheunitinterval(see[85–87]),isaningeniousandhighlyesthetic dethronement of all existing theories of truth and of all simplistic semantics, including Aristotele’s, Tarski’s, Carnap’s, and Kripke’s perspectives. It goes without saying that wheneverthesimplisticconceptoftruthislost,everythingdependentwillalsovanish.That means that following the fall of A above, B–G will automatically collapse. Fortunately, thereisacompletesubstituteforallofthat,thefuzzytheory,whichiscapableofreigning immediately as the new disciplinary matrix. Its availability as a more than perfect substitute is, thus, the reason of its success.5 As a substitute, the fuzzy theory is a many-valued conceptual system. As stated in B above, a consequence of this removal of the Aristotelian two-valuedness is that the principlesofexcludedmiddleandnon-contradiction,B–Dabove,arealsopasse´ because theunionofafuzzysetXanditscomplementXcisnotnecessarilythebaseset,andtheir intersection is not necessarily empty, i.e. X[Xc 6(cid:136)O and X\Xc 6(cid:136)?. It took approximately 2300 years to refute the Aristotelian position against fuzziness statedinEaboveandtodemonstratethatthereare,first,intermediatesbetweenmembers andnon-membersofaclass,andsecond,numberswhichareneitheroddnornot-odd,e.g. the fuzzy number ‘approximately 2300’. Thus far, the overall effect is an implosion of the classical concept of two-valued inferencesketchedinGaboveand,asaconsequence,thedeceaseofalltwo-valuedlogics. WewillreturntothispointinSection4.Letusfirstsupplementthenewparadigmwitha novel facet, invalidating F above, to complete our goodbye to A–G above. 3. Fuzzy ontology Asalreadyindicated,thehumanreasonseemstoholdatwo-valuedontologyreflectedin thecommonbeliefthat‘everythingisorisnot,thereisnointermediatebetweenbeingand nonbeing’.ThisAristoteliandoctrineofcrispexistencecitedinFabovethathasgoverned Westernphilosophy,logic,science,religion,andcommonsenseforthelasttwomillennia, nolongerapplies.Tosketchthisoutlookwewilladdtotheclassoffuzzyquantifiersthe fuzzy existence operator ‘‘there is to some extent’’, denoted by 90. The sentence 90x(Px) thusreadsthereistosomeextentanxsuchthatxisP.LetPbeanypredicatethatsignifiesa corresponding set P with the membership function m . Then we may define: P 5Merecriticismsofadisciplinarymatrixextendedfromwithinanemptyholewillneversufficetoforcea shiftbecausethe questionwillarise: a shifttowhere?Forexample, wehave as yet encounteredmanysuch vacuous attempts in medicine, e.g. homeopathy and psychosomatics, which have beenvainly trying to shift modernmedicinefromitsnatural–scientificconceptsandmethodsto:where?Nobodyknows. K.Sadegh-Zadeh/ArtificialIntelligenceinMedicine21(2001)1–25 7 Definition 1. 90x(cid:133)Px(cid:134) if and only if 9r(cid:133)m (cid:133)x(cid:134)(cid:136)r). P Anobjectxwhosegradedexistenceisassertedbyastatementoftheform90x(Px),isa fuzzyobject.AnexampleisDavid.Heisyoungtotheextent0.7.Thus,thedefinitionabove implies that there is to some extent someone who is young. The proposition that to the extent 0.2 the earth is a big planet provides a second example, i.e. the fuzzy object the earth. Elementary particles of quantum physics are additional examples which Werner Heisenberg has tried to grasp by his uncertainty principle. Obviously, any fuzzy set defines fuzzy objects. The fuzzy existence of such an object maybemeasuredbyanewoperator 90 thatisread‘relativetoPthereistotheextentr’. P r Accordingly,theexpression 90x(cid:133)Px(cid:134)meansthatrelativetoPthereistotheextentranx P r suchthatxisP.InplaceofDefinition1,thismetricexistenceoperatormaybedefinedas follows: Definition 2. 90x(cid:133)Px(cid:134) if and only if 9r(cid:133)m (cid:133)x(cid:134)(cid:136)r(cid:134). P r P WithregardtoourfirstexampleabovewhichsaidthatDavidisyoungtotheextent0.7, this new concept implies that relative to the predicate young there is to the extent 0.7 someone who is young, i.e. David. According to this new concept, a fuzzy object exists only relative to a particular predicateandtoaparticularextentbetween1and0.Thetransitionfrombeingtononbeing andviceversaisthusgradualratherthanabrupt.Pantarei.Everythingexiststoanextent r (cid:20)1.Ifthisr (cid:136)0forallpredicatesofaparticularlanguage,theobjectdoesnotexistwith respect to this language. However, it may exist with respect to another language. That means,first,thatalanguageinducesanontology,andsecond,thatbeingandnonbeingis relativetolanguagesandlogics.‘‘Changeyourlanguageorlogic,andyouwillseeanother world’’ ([48], p. 171). Thisamountsroughlytosayingthattobeistobeafuzzyobject,i.e.amemberofafuzzy set within a particular language [50].6 4. Fuzzy proof theory Ithasbeensaidabovethatwithinthenewdisciplinarymatrixthetwo-valuedconceptof classical–logicalinferenceimplodes.Asaresult,classicallogicceasestoserveasameans of reasoning in science and technology. This decease is not only due to the above- mentionedimplosion.Itisalsocausedbytheunparalleledpoweroffuzzylogictocopewith vaguenessinthewidestsense,i.e.withpartiallytruestatements,fuzzyconnectives,fuzzy predicates, predicate modifiers, and fuzzy quantifiers. 6Viewedfromthisperspective,Quine’swell-knownaccountofontologywhichsaysthat‘‘tobeistobethe valueofavariable’’([42],p.15)appearssomewhatsimplistic.Indevelopingmyontologyovertheyears,Ihave profitedfromdiscussionswithmyfriendProfessorNewtonC.AffonsodaCosta,UniversityofSaoPaulo,and fromhispublicationsandmanuscripts,e.g.[14]. 8 K.Sadegh-Zadeh/ArtificialIntelligenceinMedicine21(2001)1–25 Capable of dealing with these and other vague ingredients of natural languages and commonsense reasoning, fuzzy logic started with the doctrine of being a logic of approximate reasoning based on rules of inference whose validity is approximate rather thanexact(cf.[83–87,90,5]).Althoughithasbecomeatrulystrongtheoryofreasoningand controlinthemeantime,itsinitialdoctrine continues tobewidelymisunderstood.Many traditionallogiciansandmathematiciansarestillhesitantabouttakingalogicseriouslythat reliesonapproximaterulesofinference(cf.,e.g.[27,28]).Thisissobecauseithasnotyet beenproperlyascertainedwhatisactuallybroughtaboutbyfuzzylogic.Oneconsidersits surface structure and overlooks the processes in its deep structure. In the depth offuzzy logicthefollowingdevelopmentmaybeobservedwhichrepresentsaphilosophicallymost intriguing aspect of the revolution. WehavealreadystatedthattheAristoteliantwo-valuednessisbeingreplacedwiththe fuzzy-theoretical many-valuedness. This substitution is vividly reflected in the fuzzy- theoretical treatment of truth as a many-valued linguistic variable. However, this many- valuednessnotonlyconcernsfactualtruthsandfalsehoodswhenthetruthorfalsehoodofa statementsuchas,forexample,‘snowiswhite’isconsidered,butalsoaffectstheconcept oflogicaltruththatcharacterizesthemetalinguisticrelationofclassical-logicalinference sketchedinGinSection2.Thatmeansthatinthedepthoffuzzytheorythereisahidden, metalinguistic concept of many-valuedness, i.e. inferential many-valuedness, that will moreandmoreemergeasafuzzyprooftheoryinthenearfuture.Withthisprooftheoryat its disposal, fuzzy theory will conquer all mathematical sciences. To shed some light on this imminent course, consider the following, prototypical fuzzy-logical inference: aissmall (cid:17)statementa 1 aandbareapproximatelyequal (cid:17)statementa 2 bismoreorlesssmall (cid:17)statementb Inferencesofthistypeareusuallybaseduponrulessuchascompositionalruleofinference orgeneralizedmodusponensorsomethingelse,andarecommonlyviewedasimprecise. Andsincewhatisimpreciseisnotgood,fuzzylogicisnotgood.Averdictofthiskindis strange and wrong simply because it evaluates a fuzzy inference as above from the outmoded perspective of two-valued logic where a statement b either definitely is, or definitely is not, a consequence of a set S(cid:136)fa ;...;a g of premises: 1 n A set S(cid:136)fa ;...;a g of premises classical–logically implies a conclusion b iff 1 n whenever the premises are true b is true. According tothisclassical-logicalconceptofinference, thesetofallconsequencesof thepremisesS,denotedbycons(S),isthesetofallstatementsthatareclassical-logically implied by S, i.e. cons(cid:133)S(cid:134)(cid:136)fbjSclassical(cid:255)logicallyimpliesbg The set cons(S) is crisp. This means that given a set S of n(cid:21)1 premises a ;...;a , 1 n traditionally a particular statement b is considered to be implied by S if it is true that b2cons(cid:133)S(cid:134),whileitisconsiderednottobeimpliedbySifitistruethatb2=cons(cid:133)S(cid:134).And sinceitisnotevidentifastatementsuchas‘bismoreorlesssmall’aboveisorisnotan K.Sadegh-Zadeh/ArtificialIntelligenceinMedicine21(2001)1–25 9 element of the set cons({a is small, a and b are approximately equal}), the inference is labeled ‘imprecise’, ‘vague’, or ‘uncertain’. A remedy for this perpetual mistake is provided by Zadeh’s fuzzifiability principle: Any theory, X, may be fuzzified by replacing the concept of a set in X by the more general concept of a fuzzy set ([98], p. 816). Thus,letusfuzzifythesetofconsequencesofastatementset,cons(S).Thistaskmaybe accomplished by constructing a membership function m that assigns a number cons(S) m (cid:133)b(cid:134)2(cid:137)0;1(cid:138) to a statement b as the degree of its belonging to the set cons(S). cons(cid:133)S(cid:134) As a result, we obtain a concept of graded inference that we also call graded logical implication, graded deduction, or graded reasoning (cf. [45]). LetSbethesetofallsyntacticallyadmissiblesentencesofaparticularlanguage.Acrisp logic L over this language is a mapping of the form ) :2S(cid:2)S!f0;1g L with) beingitsimplicationoperatorand2SthepowersetofSsuchthatforallS22Sand L b2S we have ) (cid:133)S;b(cid:134)(cid:136)1 if according to logic L the statement b follows from the L statement set S, and ) (cid:133)S;b(cid:134)(cid:136)0, otherwise. By contrast, a fuzzy logic FL over that L language is a generalized mapping of the form ) :F(cid:133)2S(cid:134)(cid:2)S!(cid:137)0;1(cid:138) FL withF(2S)beingthefuzzypowersetofSsuchthat) (cid:133)S;b(cid:134)(cid:136)r saysthataccordingto FL logicFLthestatementbfollowsfromStotheextentr 2(cid:137)0;1(cid:138).Theavailabilityofsucha fuzzy implication operator, ) , would enable us to define our envisaged membership FL function m above as follows: cons(S) m (cid:133)b(cid:134)(cid:136)riff ) (cid:133)S;b(cid:134)(cid:136)r: cons(cid:133)S(cid:134) FL And that means m (cid:133)b(cid:134)(cid:136)) (cid:133)S;b(cid:134): cons(cid:133)S(cid:134) FL TheextenttowhichastatementbisamemberoftheconsequencesofSis,thus,thedegree of its deducibility from S. We would in this way obtain the fuzzy set cons(S) of consequences of the premises S: cons(cid:133)S(cid:134)(cid:136)f(cid:133)b;r(cid:134)jr (cid:136)m (cid:133)b(cid:134)g(cid:136)f(cid:133)b;r(cid:134)jr (cid:136)) (cid:133)S;b(cid:134)g: cons(cid:133)S(cid:134) FL What fuzzy logic is actually doing will give birth just to such a graded concept of deducibility creating a quantitative logic that may be called a fuzzy proof theory. A promisingapproachtothisgoalistheinterpretationoftherulesoffuzzyinferenceasrules of fuzzy constraint propagation [97,100].7 7Itistemptingtointerpretfromthisperspectivethedevelopmentoflogicasahistoryofrecognizingand handlingthephenomenonoffuzzyconstraintpropagation.Theconceptofinferenceinalltraditional,deductive logics is a truth preserving relation between premise and conclusion. And that means that all traditional, deductive logics are theories of the propagation of the single constraint ‘‘true’’. But there are innumerable constraints, including the entire term set T(cid:133)truth(cid:134)(cid:136)ftrue;nottrue;verytrue;quitetrue;false;...g of the linguistic variable truth itself, whose propagation is being studied in fuzzy logic. Also Rudolf Carnap with hisprobability-basedinductivelogicmayhavehadsomekindofaquantitativelogicinmind[10]. 10 K.Sadegh-Zadeh/ArtificialIntelligenceinMedicine21(2001)1–25 Whiletheconceptofinferenceofthequantitativelogicaboveisanumericalvariable,a qualitativefuzzylogicwouldemergefromtreatingthenotionofinferenceasalinguistic variable. For example, let the sentence ‘S implies b’ be written in prefix notation as implies(S, b). Here, ‘implies’ is a binary linguistic variable. A possible term set for this linguistic variable, T (implies), is exemplified by the following arrangement: T(cid:133)implies(cid:134)(cid:136)fabsolutely;strongly;quitestrongly;verystrongly;notstrongly; weakly;veryweakly;...etc:...g: Inclinicalmedicine,forinstance,aqualitativefuzzylogicwouldenablethephysicianto judge to what extent the patient’s data implies a particular diagnosis. For example, the result of such a diagnostic reasoning may be: implies(cid:133)patient data[KB; thepatienthasdiabetes(cid:134)(cid:136)strongly implies(cid:133)patient data[KB; thepatienthashepatitis(cid:134)(cid:136)veryweakly wherepatient_datainthepremisescompriseacollectionofstatementsaboutthepatient’s complaints,symptoms,andsigns,andKBistheknowledgebaseused.Alternatively,the implication relation may also be constructed as ‘b is implied by S’, expressed by the linguistic variable is_implied(S, b) with the term set: T(cid:133)is implied(cid:134)(cid:136)fhigh;medium;low;veryhigh;verylow;...etc:...g: In this case, the physician may arrive, for example, at the clinical judgment: is implied(cid:133)patient data[KB; thepatienthasdiabetes(cid:134)(cid:136)veryhigh; is implied(cid:133)patient data[KB; thepatienthashepatitis(cid:134)(cid:136)quitelow: Ineithercase,wewouldinclinicalreasoningbecomeabletoexploitthepowerfultheories of linguistic variables, information granulation, and computing with words [81,82,85– 89,95,97,99,100]. 5. Fuzzy-theoretical worldmaking The development and application offuzzy theory is steadily accelerating. There is no doubtthatinafewyearsthetheorywillconstitutetheuniversaldisciplinarymatrixinall areas of science, humanities, technology, and human reasoning. The three main pillars uponwhichitwasinitiallybuiltandstillrestsandgrowsarefuzzysettheory,thetheoryof linguisticvariables,andfuzzylogic.AswasalreadyreferredtoinSection1,themotivation behindthisinnovationhasbeentheperceptionthatforcopingwiththeanalysisofhighly complex systems such as the animate ones ‘‘we need a radically different kind of mathematics, the mathematics of fuzzy or cloudy quantities...’’ ([76], p. 857). Asamathematicallyorientedsystemtheorist,Ihadbeenconditionedtobelievethat theanalyticaltoolsbasedonsettheoryandtwo-valuedlogicwereallthatwasneeded to build a framework for a precise, rigorous and effective body of concepts and techniques for the analysis of almost any kind of man-made or natural system,

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The Fuzzy Revolution: Goodbye to the Aristotelian Weltanschauung. Kazem Sadegh-Zadeh*. Theory of Medicine Department, University of MuÈnster Medical
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