The Future Circle of Healthcare: AI, 3D Printing, Longevity, Ethics, and Uncertainty Mitigation PDF
Preview The Future Circle of Healthcare: AI, 3D Printing, Longevity, Ethics, and Uncertainty Mitigation
Future of Business and Finance Sepehr Ehsani Patrick Glauner Philipp Plugmann Florian M. Thieringer Editors The Future Circle of Healthcare AI, 3D Printing, Longevity, Ethics, and Uncertainty Mitigation Future of Business and Finance The Future of Business and Finance book series features professional works aimed at defining, describing and charting the future trends in these fields. The focus is mainly on strategic directions, technological advances, challenges and solutions which may affect the way we do business tomorrow, including the future of sustainability and governancepractices. Mainly written by practitioners, consultants and academic thinkers, the books are intended to spark and inform furtherdiscussionsanddevelopments. Sepehr Ehsani • Patrick Glauner • Philipp Plugmann • Florian M. Thieringer Editors The Future Circle of Healthcare AI, 3D Printing, Longevity, Ethics, and Uncertainty Mitigation Editors SepehrEhsani PatrickGlauner DepartmentofPhilosophy AppliedComputerScience UniversityCollegeLondon DeggendorfInstituteofTechnology London,UK Deggendorf,Bayern,Germany RoninInstituteforIndependent WoxsenUniversity,Hyderabad,India Scholarship,Montclair,NJ,USA PhilippPlugmann FlorianM.Thieringer SRHUniversityofAppliedHealthSciences Cranio-Maxillo-FacialSurgery CampusRheinland,Leverkusen and3DPrintLab,UniversityHospitalBasel Rhine-Westphalia,Germany Basel,Basel-Stadt,Switzerland WoxsenUniversity,Hyderabad,India SwissMAMResearchGroup SmartImplants-MIRACLEII DepartmentofBiomedicalEngineering UniversityofBasel,Allschwil Basel-Landschaft,Switzerland ISSN2662-2467 ISSN2662-2475 (electronic) FutureofBusinessandFinance ISBN978-3-030-99837-0 ISBN978-3-030-99838-7 (eBook) https://doi.org/10.1007/978-3-030-99838-7 ©TheEditor(s)(ifapplicable)andTheAuthor(s),underexclusivelicensetoSpringerNatureSwitzerland AG2022 Chapters1,4,12,and20arelicensedunderthetermsoftheCreativeCommonsAttribution4.0Interna- tionalLicense(http://creativecommons.org/licenses/by/4.0/). Forfurtherdetailsseelicenseinformation inthechapters. Thisworkissubjecttocopyright.AllrightsaresolelyandexclusivelylicensedbythePublisher,whether thewhole orpart ofthematerial isconcerned, specifically therights oftranslation, reprinting, reuse ofillustrations, recitation, broadcasting, reproductiononmicrofilmsorinanyotherphysicalway,and transmissionorinformationstorageandretrieval,electronicadaptation,computersoftware,orbysimilar ordissimilarmethodologynowknownorhereafterdeveloped. Theuseofgeneraldescriptivenames,registerednames,trademarks,servicemarks,etc.inthispublication doesnotimply,evenintheabsenceofaspecificstatement,thatsuchnamesareexemptfromtherelevant protectivelawsandregulationsandthereforefreeforgeneraluse. Thepublisher,theauthors,andtheeditorsaresafetoassumethattheadviceandinformationinthisbook arebelievedtobetrueandaccurateatthedateofpublication.Neitherthepublishernortheauthorsor theeditorsgiveawarranty,expressedorimplied,withrespecttothematerialcontainedhereinorforany errorsoromissionsthatmayhavebeenmade.Thepublisherremainsneutralwithregardtojurisdictional claimsinpublishedmapsandinstitutionalaffiliations. ThisSpringerimprintispublishedbytheregisteredcompanySpringerNatureSwitzerlandAG Theregisteredcompanyaddressis:Gewerbestrasse11,6330Cham,Switzerland Contents Introduction:Trends,Puzzles,andHopesfortheFutureofHealthcare... 1 Sepehr Ehsani, Patrick Glauner, Philipp Plugmann, andFlorianM.Thieringer InnovationsinPsychiatricCareModels:LessonsfromthePast toInformtheFuture............................................................. 25 KristinBeizai,AshleyStone,andYashJoshi MobileSensorsinHealthcare:Technical,Ethical,andMedical Aspects ............................................................................ 41 JensEckstein NewHorizonsinStudyingtheCellularMechanismsofAlzheimer’s Disease............................................................................. 51 SepehrEhsani HarnessingAIandGenomicstoAccelerateDrugDiscovery................ 89 AmirFeiziandJahirM.Gutierrez EthicalChallengesinApplyingNewTechnologiesinOrthopedic Surgery............................................................................ 107 MasoudGhalambor AnAssessment oftheAIRegulationProposedbytheEuropean Commission....................................................................... 119 PatrickGlauner Post-TruthImplicationsforCOVID-EraHealthcare:Verification, Trust,andVaccineSkepticism.................................................. 129 AaronJamesGoldman PatentsonInventionsInvolvingAIintheLifeSciencesand Healthcare ........................................................................ 147 AnnaKatharinaHeide RedesigningRelations:CoordinatingMachineLearningVariables andSociobuiltContextsinCOVID-19andBeyond .......................... 179 HannahHowland,VadimKeyser,andFarzadMahootian v vi Contents SensorDevices,theSourceofInnovativeTherapyandPrevention ........ 207 Anna Kasparbauer,VeronikaReisner, Cosima Schenk, Anna Glas, HelanaLutfi,OscarBlanco,andThomasSpittler DigitalandComputationalPathology:ASpecialtyReimagined ........... 227 Tim-RasmusKiehl ModernHomeCare:AGlimpseintotheFutureofPatient-Centered HealthcareSystems .............................................................. 251 HorstKunhardt Teledermatology:CurrentIndicationsandFuturePerspectives ........... 263 EstefaníaLang,AliceMartin,andElienWallaeys UsingArtificialIntelligencefortheSpecificationofm-Healthand e-HealthSystems................................................................. 273 KevinLano,SobhanY.Tehrani,MohammadUmar,andLyanAlwakeel TheOutlookforNovelPharmaceutics......................................... 301 MaryamParhizkarandDimitriosTsaoulidis The FutureOpenInnovationApproachin HealthCareNeeds Patients’Support................................................................. 317 JuliaPlugmannandPhilippPlugmann UncertaintyinMedicine:AnActiveDefinition............................... 329 ErmanSozudogru InnovationsforSustainableHealthcare ....................................... 343 ThomasSpittlerandHelanaLutfi Medical Additive Manufacturing in Surgery: Translating InnovationtothePointofCare................................................. 359 FlorianM.Thieringer,PhilippHonigmann,andNehaSharma TheFutureofMedicalEducation.............................................. 377 MarkH.WanandQiuNingLee PersonalizedDental Medicine with Specific Focus on the Use ofDatafromDiagnosticDentalImaging...................................... 385 AndyW.K.YeungandMichaelM.Bornstein Index............................................................................... 399 About the Editors SepehrEhsani (https://ehsani.info/)studiedlaboratorymedicineandpathobiology at the University of Toronto at the BSc and PhD levels. While completing his undergraduate degree, he was part of a neuropathology research group. During his postgraduate study, he worked in a protein biology lab with a focus on the prion protein implicated in a number of neurodegenerative diseases. Ehsani was a postdoctoralfellow at the Whitehead Institute for Biomedical Research and the MIT Computer Science and AI Lab, both in Cambridge, Massachusetts, from 2013 to 2016. There, he worked mainly on the alpha-synuclein protein—another neurodegenerative disease-linked protein. In 2015 and 2016, he was a Teaching FellowatHarvardCollege’sPrograminGeneralEducation.He hasbeenstudying analyticphilosophyatUniversityCollegeLondonsince2017andisresearchingthe augmentationofmechanisticexplanationsofdiseasewithceterisparibuslawsand cellbiologicalprinciples. Patrick Glauner (https://www.linkedin.com/in/glauner/) is a Full Professor of Artificial Intelligence at Deggendorf Institute of Technology (Germany) since age 30 and the Ramon O’Callaghan Professor of Technology Management and Innovation at Woxsen University (India). He has been ranked by CDO Magazine and Global AI Hub among the worldwide academic data leaders. In parallel to his academic roles, he is the Founder and CEO of skyrocket.ai GmbH, an AI consulting firm. As an expert witness, he advised the parliaments of France, Germany,andLuxembourg.HealsoregularlyadvisespoliticiansontheEuropean, federal,state,andlocallevels.Hehaspublishedfourbooks:“CreatingInnovation Spaces” (Springer,2021), “Digitalisierungskompetenzen:Rolle der Hochschulen” (Hanser, 2021), “Digitalization in Healthcare” (Springer, 2021), and “Innovative Technologies for Market Leadership” (Springer, 2020). His works on AI were featured by New Scientist, McKinsey, Imperial College London, Times Higher Education,Coursera, Udacity, the LuxembourgNational Research Fund, Towards Data Science, Süddeutsche Zeitung, Tagesspiegel, Deutsche Welle, Bayerischer Rundfunk,WestdeutscherRundfunk,Wehrtechnik,Konstruktionspraxis,andothers. HewaspreviouslyHeadofDataAcademyatAlexanderThammGmbH,Innovation Manager for Artificial Intelligence at Krones Group, a Fellow at the European Organization for Nuclear Research (CERN), and a visiting researcher at the University of Quebec in Montreal (UQAM). He graduated as valedictorian from vii viii AbouttheEditors Karlsruhe University of Applied Sciences with a BSc in Computer Science. He subsequentlyreceivedanMScinMachineLearningfromImperialCollegeLondon, anMBAfromQuanticSchoolofBusinessandTechnology,andaPhDinComputer Science from the University of Luxembourg. He is an alumnus of the German NationalAcademicFoundation(StudienstiftungdesdeutschenVolkes). PhilippPlugmann (https://www.linkedin.com/in/prof-dr-dr-plugmann/)hasbeen doing multidisciplinary work for the last 22 years in parallel to practicing as a dentist in his own clinic in Leverkusen, Germany. He is also a Full Professor of InterdisciplinaryPeriodontologyandPreventionattheSRH UniversityofApplied HealthSciences(Germany)andProfessorofPracticeatWoxsenUniversity(India). His first book on innovation in medical technology, published in 2011, was reviewed by Cisco. His second book on innovation, published with Springer in 2018, had more than 135,000 chapter downloads during the first 48 months after its release. Previously, he held multiple adjunct faculty appointments for over seventeen years, winning multiple teaching awards. He also holds an MBA in Health Care Management, an MSc in Business Innovation (both from the EBS University of Business and Law, Germany), and an MSc in Periodontology and Implant Therapy (DGParo, German Society for Periodontology); he is currently pursuing his third doctorate. Prof. Plugmann has given research talks in the field of innovation at conferences at Harvard Business School (USA), Berkeley Haas School of Business (USA), Max Planck Institute for Innovation and Competition (Germany), Max Planck Institute for Social Law and Social Policy (Germany), andNanyangTechnologicalUniversity(Singapore).Heisaserialentrepreneurand advisortoseveralcompanies,includingaglobaltechnologyconsultancyasaSenior Advisor for Life Science and Health Care. Since 2020, he is a reviewer for the FederalHealthBulletin(Bundesgesundheitsblatt). Florian M. Thieringer (https://www.linkedin.com/in/thieringer/) studied medicine at the TU Munich, dentistry at the LMU Munich, and health business administration at the FAU Erlangen-Nuremberg. He is an oral- and cranio- maxillofacial surgeon as well as a medical 3D expert with a focus on tumor, trauma,reconstructive,andorthognathicsurgery.LocatedattheUniversityHospital Basel and University of Basel, Switzerland, FMT is currently senior surgeon and Privatdozent for oral and cranio-maxillofacial surgery. He is also a Head of the Medical Additive Manufacturing Research Group at the University of Basel’s Department of Biomedical Engineering. He has earned international recognition forhisexpertiseincomputerassistedsurgeryandmedicaladditivemanufacturing, extensively exploring and promoting the integration of virtual surgical planning, 3Dprinting,andotherinnovativetechnologiesatthepoint-of-care(suchasadditive manufacturing of patient-specific implants in various biomaterials, including bioprintingandregenerativesurgery).Since2016,hehasactedasaCo-Directorof themultidisciplinary3DPrintLabattheUniversityHospitalofBasel.Since2020, he has been a Co-Principal Investigator of the innovative MIRACLE 2 project (Minimally Invasive Robot-Assisted Computer-guided LaserosteotomE). Funded bytheWernerSiemensFoundation,the12mSwiss Francresearchprojectaimsto AbouttheEditors ix developaroboticendoscopetoperformcontact-freebonesurgerywithlaserlight. Perfectlyfittingpatient-specificimplantswillbedesignedinAR/VRforproduction throughintra-andextra-corporeal3Dprinting.
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