The Exquisite Machine: The New Science of the Heart PDF
Preview The Exquisite Machine: The New Science of the Heart
THE EXQUISITE MACHINE THE EXQUISITE MACHINE THE NEW SCIENCE OF THE HEART SIAN E. HARDING The MIT Press Cambridge, Massachusetts London, England © 2022 Sian E. Harding All rights reserved. No part of this book may be reproduced in any form by any electronic or mechanical means (including photocopying, recording, or information storage and retrieval) without permission in writing from the publisher. The MIT Press would like to thank the anonymous peer reviewers who provided comments on drafts of this book. The generous work of academic experts is essential for establishing the authority and quality of our publica- tions. We acknowledge with gratitude the contributions of these otherwise uncredited readers. This book was set in Bembo Book MT Pro by New Best-set Typesetters Ltd. Library of Congress Cataloging- in- Publication Data Names: Harding, Sian E., author. Title: The exquisite machine : the new science of the heart / Sian E. Harding. Description: Cambridge, Massachusetts : The MIT Press, [2022] | Includes bibliographical references and index. Identifiers: LCCN 2021052081 | ISBN 9780262047142 (hardcover) Subjects: LCSH: Heart—Diseases—Treatment. | Heart—Diseases— Prevention. Classification: LCC RC683.8 .H37 2022 | DDC 616.1/2—dc23/ eng/20211124 LC record available at https://lccn.loc.gov/2021052081 10 9 8 7 6 5 4 3 2 1 This book is dedicated to Ray and Elizabeth Harding “and this is the wonder that’s keeping the stars apart i carry your heart (i carry it in my heart)” — e.e. cummings CONTENTS 1 INTRODUCTION 1 2 THREATS TO THE HEART: A THOUSAND NATURAL SHOCKS 9 3 THE SCIENCE OF THE REALLY SMALL 29 4 BIG DATA— MANY HEARTS THAT BEAT AS ONE? 45 5 THE PLASTIC HEART 69 6 THE RESPONSIVE HEART— EMOTION IN MOTION 83 7 CAN YOU (NOT) DIE OF A BROKEN HEART? 99 8 THE GENDERED HEART 119 9 THE MECHANICAL HEART 135 10 CAN STEM CELLS HELP US GROW A NEW HEART? 151 11 WHEN WILL THE FUTURE BE HERE? 173 Acknowledgments 193 Notes 195 Index 215
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