UITNODIGING About the Author T h e E Linda van Zutphen was born in Emmeloord m Hierbij nodig ik u van harte uit o (the Netherlands) on November 9th 1984. She t The Emotional Rollercoaster called voor het bijwonen van de i o openbare verdediging van graduated from secondary school at Zuyderzee n a mijn proefschrift College in Emmeloord in July 2003, after which l R Borderline Personality Disorder o she started her study Human Movement l l e Science at the University of Groningen. She rc Neural Correlates of Emotion Regulation and Impulsivity The Emotional Rollercoaster called o Borderline Personality Disorder received her master’s degree on August 31 a s t Neural Correlates of Emotion 2008. To study the relationship between brain e r Regulation and Impulsivity and behavior, she subsequently started the c a l research master Cognitive Neuropsychology le d Linda van Zutphen at the Free University Amsterdam, where B De promotie vindt plaats op o Donderdag 23 maart 2017 she obtained her second master’s degree on r d om 16.00 uur August 31 2010. In August 2011, she began e r l i her PhD project at the Department of Clinical n in de aula van de e Psychological Science at Maastricht University. P Universiteit Maastricht, e Minderbroedersberg 4-6 r She is currently working as a post-doctoral so te Maastricht. researcher in the same department, where n a she is continuing her research on change in lit Aansluitend bent u y van harte welkom op de receptie brain activation of emotion regulation and D voor tevens een hapje eten. i s impulsivity during the course of psychotherapy o r d in borderline personality disorder. e r Linda van Zutphen [email protected] Paranimfen Suzanne Brugman [email protected] Conny Quaedflieg [email protected] L i n d a v a n Z u t p h e n 14345_Zutphen_OM.indd 1 25-01-17 12:31 The Emotional Rollercoaster called Borderline Personality Disorder Neural Correlates of Emotion Regulation and Impulsivity Linda van Zutphen 14345_Zutphen_BW.indd 1 27-01-17 15:01 Colophon Design cover picture: Marga, Francien & Vincent van Zutphen Lay-out: Nikki Vermeulen | Ridderprint BV Printing: Ridderprint BV | www.ridderprint.nl ISBN: 978-94-6299-515-4 © Copyright Linda van Zutphen, Maastricht 2017 Al rights are reserved. No part of this book may be reproduced or transmitted in any form or any means, without permission from the author, or, when appropriate, the publisher of the article. 14345_Zutphen_BW.indd 2 27-01-17 15:01 The Emotional Rollercoaster called Borderline Personality Disorder Neural Correlates of Emotion Regulation and Impulsivity Proefschrift Ter verkrijging van de graad van doctor aan de Universiteit Maastricht, op gezag van de Rector Magnificus, Prof. Dr. Rianne M. Letschert, volgens het besluit van het College van Decanen, in het openbaar te verdedigen op Donderdag 23 maart 2017 om 16:00 uur door Carolina Petronella van Zutphen 14345_Zutphen_BW.indd 3 27-01-17 15:01 Promotores Prof. dr. A.R. Arntz Prof. dr. R. Goebel Copromotor Dr. N. Siep Beoordelingscommissie Prof. dr. Beatrice de Gelder (voorzitter) Prof. dr. Bernet Elzinga (Leiden University) Dr. Jill Lobbestael Dr. Anne Roefs Prof. dr. Christian Schmahl (Medical Faculty Mannheim/Heidelberg University, Germany) The research presented in this dissertation was conducted in the program “Open Research Area in Social Sciences”, supported by the Netherlands Organization for scientific Research (NWO), grant number 464-10-080 awarded to Prof. dr. R. Goebel, by the German Research Foundation, grant number JA1785/3-1 awarded to Dr. G.A. Jacob 14345_Zutphen_BW.indd 4 27-01-17 15:01 Table of contents Chapter 1 General Introduction 7 Chapter 2 Emotional sensitivity, emotion regulation and 21 impulsivity in borderline personality disorder: A critical review of fMRI studies Chapter 3 Always on guard: 55 Emotion regulation in borderline personality disorder compared to non-patients and cluster-c personality disorder patients Chapter 4 Impulse control under emotion processing: 85 an fMRI investigation in borderline personality disorder compared to non-patients and cluster-c personality disorder patients Chapter 5 Deficient amygdala-prefrontal intrinsic connectivity after 111 effortful emotion regulation in borderline personality disorder Chapter 6 Summary and General discussion 145 Valorization Addendum 173 Samenvatting (Dutch Summary) 181 Dankwoord (Acknowledgements) 193 List of Publications 199 14345_Zutphen_BW.indd 5 27-01-17 15:01 14345_Zutphen_BW.indd 6 27-01-17 15:02 General Introduction 1 14345_Zutphen_BW.indd 7 27-01-17 15:02 14345_Zutphen_BW.indd 8 27-01-17 15:02
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