The Clinical Chemistry of Laboratory Animals, Third Edition

1162 Pages·2018·15.01 MB·English

by  David M. Kurtz

The Clinical Chemistry of
Laboratory Animals
Third Edition

The Clinical Chemistry of
Laboratory Animals
Third Edition
Edited by:
David M. Kurtz and Gregory S. Travlos
CRC Press
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Library of Congress Cataloging-in-Publication Data
Names: Kurtz, David M., editor. | Travlos, Gregory S., editor.
Title: Clinical chemistry of laboratory animals / [edited by] David M. Kurtz and Gregory S. Travlos.
Description: Third edition. | Boca Raton : Taylor & Francis, 2017. | Includes
bibliographical references and index.
Identifiers: LCCN 2016055474 | ISBN 9781420091137 (hardback : alk. paper)
Subjects: | MESH: Animals, Laboratory--metabolism | Clinical Chemistry
Tests--methods
Classification: LCC SF996.5 | NLM QY 50 | DDC 636.088/5--dc23
LC record available at https://lccn.loc.gov/2016055474
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Dedication
To Cat
To Kim, Hannah and Kyle
To Judith S. Prescott
To Our Authors

Contents
Dedication ..........................................................................................................................................v
List of Contributors ...........................................................................................................................xi
List of Reviewers ...........................................................................................................................xiii
Chapter 1 The Laboratory Mouse .................................................................................................1
Richard H. Luong
Chapter 2 The Laboratory Rat ....................................................................................................33
Nancy E. Everds and Lila Ramaiah
Chapter 3 The Laboratory Rabbit ...............................................................................................79
Anna Hampton, Tara Cotroneo, and Lesley A. Colby
Chapter 4 The Laboratory Dog .................................................................................................113
Julia Whitaker, Allison R. Rogala, Dana N. LeVine, and Craig A. Fletcher
Chapter 5 The Laboratory Pig ..................................................................................................153
Alain Stricker-Krongrad, Larry D. Brown, Guy F.Bouchard, M. Michael
Swindle, and Stan W. Casteel
Chapter 6 The Nonhuman Primate ...........................................................................................211
Kirstin F. Barnhart
Chapter 7 The Laboratory Hamster ..........................................................................................289
Charles B. Clifford and Joe H. Simmons
Chapter 8 The Laboratory Guinea Pig ......................................................................................305
Patrick Sharp
Chapter 9 The Laboratory Ferret ..............................................................................................331
Mary M. Patterson and James G. Fox
Chapter 10 The Laboratory Zebrafish and Other Fishes ............................................................345
Claudia Harper
Chapter 11 Evaluation of Hepatic Function and Injury ..............................................................367
Charles E. Wiedmeyer
vii
viii Contents
Chapter 12 Evaluation of Renal Function and Injury .................................................................407
Denise Bounous and Ernie Harpur
Chapter 13 Evaluation of Cardiovascular and Pulmonary Function and Injury ........................445
Peter O’Brien
Chapter 14 Evaluation of Skeletal Muscle Function and Injury .................................................475
Carol B. Grindem, Jennifer A. Neel, and Carolina Escobar
Chapter 15 Evaluation of Bone Function and Injury ..................................................................515
Holly L. Jordan and Bruce E. LeRoy
Chapter 16 Biochemistry of Immunoglobulins ..........................................................................551
Barbara R. von Beust and Gregory S. Travlos
Chapter 17 Complement .............................................................................................................587
Barbara R. von Beust and Gregory S. Travlos
Chapter 18 Transport Proteins ....................................................................................................645
Claire L. Parry
Chapter 19 Acute Phase Proteins ................................................................................................677
Claire L. Parry
Chapter 20 Carbohydrate Metabolism ........................................................................................745
Owen P. McGuinness and Masakasu Shiota
Chapter 21 Lipids ........................................................................................................................777
Dana Walker and Lindsay Tomlinson
Chapter 22 Electrolytes, Blood Gases and Acid–Base Balance .................................................873
Isabel A. Lea, Susan J. Borghoff, and Gregory S. Travlos
Chapter 23 Hormones .................................................................................................................939
Jerome M. Goldman, Lori K. Davis, and Ralph L. Cooper
Chapter 24 Vitamins, Selected Diet-Derived Factors, and Minerals........................................1007
Robert B. Rucker, Andrea J. Fascetti, and Jennifer A. Larsen
Contents ix
Chapter 25 Development of Biomarkers ...................................................................................1093
Holly L. Jordan
Chapter 26 Statistical Methods .................................................................................................1105
Grace E. Kissling
Index .............................................................................................................................................1121