Table Of Content

The American Journal of PATHOLOGY CONTENTS FOR VOLUME 138 January 1991 Rapid Communications Evolution of /n Vitro Transformation and Tumorigenesis of HPV16 and HPV18 Immortalized Primary Cervical Epithelial Cells G. Pecoraro, M. Lee, D. Morgan, and V. Defendi Fibroblast Growth Factor Gene Expression in AIDS-Kaposi’s Sarcoma Detected by /n Situ Hybridization Luc Xerri, Jacques Hassoun, Jacqueline Planche, Veronique Guigou, Jean-Jacques Grob, Patricia Parc, Daniel Birnbaum, and Odile deLapeyriere Dystrophin Is Required for Normal Thin Filament-Membrane Associations at Myotendinous Junctions James G. Tidball and Douglas J. Law Increased Microvascular Permeability In Vivo in Response to Intradermal Injection of Neutrophil-activating Protein (NAP-2) in Rabbit Skin Nancy Van Osselaer, Jo Van Damme, Marc Rampart, and Arnold G. Herman Regular Articles Diffuse Lymphocyte-predominant Hodgkin's Disease (Diffuse Paragranuloma): A Variant of the B-cell-Derived Nodular Type M.-L. Hansmann, H. Stein, F. Dallenbach, and C. Fellbaum Vascular Cells Respond Differentially to Transforming Growth Factors Beta, and Beta, /n Vitro June Rae Merwin, Walter Newman, L. Dawson Beall, Adeline Tucker, and Joseph Madri Occurrence of Multiple Types of Human Papillomavirus in Genital Tract Lesions: Analysis by /n Situ Hybridization and the Polymerase Chain Reaction Gerard J.N uovo, MarleneM . Darfler, Chaka C. Impraim, and Susan E. Bromley Genetic Determination of Cytomegalovirus-induced and Age-related Cardiopathy in Inbred Mice: Characterization of Infiltrating Cells Patricia Price, Kim S. Eddy, Jobn M. Papadimitriou, Deborah L. Faulkner, and Geoffrey R. Shellam Mature Eosinophils Stimulated to Develop in Human Cord Blood Mononuclear Cell Cultures Supplemented with Recombinant Human Interleukin-5: Part |. Piecemeal Degranulation of Specific Granules and Distribution of Charcot-Leyden Crystal Protein Ann M. Dvorak, Takuma Furitsu, Linda Letourneau, Teruko Ishizaka, and Steven J.A ckerman Immunoreactivity and Receptor Expression of Insulinlike Growth Factor | and Insulin in Human Adrenal Tumors: An Immunohistochemical Study of 94 Cases Takibiro Kamio, Kazuto Shigematsu, Kioko Kawai, and Hideo Tsuchiyama Effects of Recombinant Tumor Necrosis Factor-alpha on Cultured Pulmonary Artery and Lung Microvascular Endothelial Monolayers Barbara Meyrick, Brian Christman, and Gary Jesmok Expression of Blood Group Antigens H-2, Le’, and Sialylated-Le* in Human Colorectal Carcinoma: An Immunohistochemical Study Using Double-labeling Techniques Harry S. Cooper, Mark J. Malecha, Carol Bass, Pantaleon L. Fagel, and Zenon Steplewski Localization of Urokinase-type Plasminogen Activator in Stromal Cells in Adenocarcinomas of the Colon in Humans Jan Grondabl-Hansen, Elisabeth Ralfkier, Lene T. Kirkeby, Peter Kristensen, LeifR .L und, and Keld Dano Phenotypic Relationships of Prostatic Intraepithelial Neoplasia to Invasive Prostatic Carcinoma Ray B. Nagle, Michael K. Brawer, Jobn Kittelson, and Virginia Clark The American Journal of PATHOLOGY CONTENTS FOR VOLUME 138 January 1991 Rapid Communications Evolution of /n Vitro Transformation and Tumorigenesis of HPV16 and HPV18 Immortalized Primary Cervical Epithelial Cells G. Pecoraro, M. Lee, D. Morgan, and V. Defendi Fibroblast Growth Factor Gene Expression in AIDS-Kaposi’s Sarcoma Detected by /n Situ Hybridization Luc Xerri, Jacques Hassoun, Jacqueline Planche, Veronique Guigou, Jean-Jacques Grob, Patricia Parc, Daniel Birnbaum, and Odile deLapeyriere Dystrophin Is Required for Normal Thin Filament-Membrane Associations at Myotendinous Junctions James G. Tidball and Douglas J. Law Increased Microvascular Permeability In Vivo in Response to Intradermal Injection of Neutrophil-activating Protein (NAP-2) in Rabbit Skin Nancy Van Osselaer, Jo Van Damme, Marc Rampart, and Arnold G. Herman Regular Articles Diffuse Lymphocyte-predominant Hodgkin's Disease (Diffuse Paragranuloma): A Variant of the B-cell-Derived Nodular Type M.-L. Hansmann, H. Stein, F. Dallenbach, and C. Fellbaum Vascular Cells Respond Differentially to Transforming Growth Factors Beta, and Beta, /n Vitro June Rae Merwin, Walter Newman, L. Dawson Beall, Adeline Tucker, and Joseph Madri Occurrence of Multiple Types of Human Papillomavirus in Genital Tract Lesions: Analysis by /n Situ Hybridization and the Polymerase Chain Reaction Gerard J.N uovo, MarleneM . Darfler, Chaka C. Impraim, and Susan E. Bromley Genetic Determination of Cytomegalovirus-induced and Age-related Cardiopathy in Inbred Mice: Characterization of Infiltrating Cells Patricia Price, Kim S. Eddy, Jobn M. Papadimitriou, Deborah L. Faulkner, and Geoffrey R. Shellam Mature Eosinophils Stimulated to Develop in Human Cord Blood Mononuclear Cell Cultures Supplemented with Recombinant Human Interleukin-5: Part |. Piecemeal Degranulation of Specific Granules and Distribution of Charcot-Leyden Crystal Protein Ann M. Dvorak, Takuma Furitsu, Linda Letourneau, Teruko Ishizaka, and Steven J.A ckerman Immunoreactivity and Receptor Expression of Insulinlike Growth Factor | and Insulin in Human Adrenal Tumors: An Immunohistochemical Study of 94 Cases Takibiro Kamio, Kazuto Shigematsu, Kioko Kawai, and Hideo Tsuchiyama Effects of Recombinant Tumor Necrosis Factor-alpha on Cultured Pulmonary Artery and Lung Microvascular Endothelial Monolayers Barbara Meyrick, Brian Christman, and Gary Jesmok Expression of Blood Group Antigens H-2, Le’, and Sialylated-Le* in Human Colorectal Carcinoma: An Immunohistochemical Study Using Double-labeling Techniques Harry S. Cooper, Mark J. Malecha, Carol Bass, Pantaleon L. Fagel, and Zenon Steplewski Localization of Urokinase-type Plasminogen Activator in Stromal Cells in Adenocarcinomas of the Colon in Humans Jan Grondabl-Hansen, Elisabeth Ralfkier, Lene T. Kirkeby, Peter Kristensen, LeifR .L und, and Keld Dano Phenotypic Relationships of Prostatic Intraepithelial Neoplasia to Invasive Prostatic Carcinoma Ray B. Nagle, Michael K. Brawer, Jobn Kittelson, and Virginia Clark Cellular Localization of Interleukin-8 and Its Inducer, Tumor Necrosis Factor-alpha in Psoriasis B. J. Nickoloff, G. D. Karabin, J. N. W. N. Barker, C. E. M. Griffiths, V. Sarma, R. S. Mitra, J. T. Elder, S. L. Kunkel, and V. M. Dixit Cytoplasmic Lipid Bodies of Human Eosinophils: Subcellular Isolation and Analysis of Arachidonate Incorporation PeterF . Weller, Rita A. Monahan-Earley, Harold F. Dvorak, and Ann M. Dvorak AIDS-related Lymphoma: Histopathology, Immunophenotype, and Association with Epstein-Barr Virus as Demonstrated by /n Situ Nucleic Acid Hybridization Stephen J. Hamilton-Dutoit, Gorm Pallesen, Maria B. FranzmannJe,n s Karkov, Finn Black, Peter Skinhoj, and Court Pedersen Monoclonal Antibodies Detect Monocyte/Macrophage Activation and Differentiation Antigens and Identify Functionally Distinct Subpopulations of Human Rheumatoid Synovial Tissue Macrophages Alisa E. Koch, James C. Burrows, Alexandra Skoutelis, Robert Marder, Peter H. Domer, Byron Anderson, and S. Joseph Leibovich Expression of IgG Fc Receptor Antigens in Placenta and on Endothelial Cells in Humans: An Immunohistochemical Study Daniel D. Sedmak, Daniel H. Davis, Upinder Singh, Jan G. J. van de Winkel, and Clark L. Anderson Anatomic Pathway of Pulmonary Fluid Leakage in Endotoxemia Induced in Rats: The Red Blood Cell Packing Method and Its Application Nobuhiko Nagata, Katsuo Sueishi, and Kenzo Tanaka Effects of Smoke Inhalation on Surfactant Phospholipids and Phospholipase A; Activity in the Mouse Lung M. Oulton, H. K. Moores, J. E. Scott, D. T. Janigan, and R. Hajela Urinary Excretion of the C5b-9 Membrane Attack Complex of Complement Is a Marker of Immune Disease Activity in Autologous Immune Complex Nephritis Charles J. Pruchno, Mark M. Burns, Matthias Schulze, RichardJ .J ohnson, Patricia J.B aker, Charles E. Alpers, and William G. Couser Tumor-secreted Vascular Permeability Factor Increases Cytosolic Ca** and von Willebrand Factor Release in Human Endothelial Cells TommyA . Brock, Harold F. Dvorak, and Donald R. Senger Transforming Growth Factor-8 Production in Anti-giomerular Basement Membrane Disease in the Rabbit Terezila Coimbra, Roger Wiggins, Jung Woo Nob, Steven Merritt, and Sem H. Phan Cortical and Subcortical Patterns of Synaptophysinlike Immunoreactivity in Alzheimer's Disease Eliezer Masliab, Robert D. Terry, Michael Alford, Richard DeTeresa, and LawrenceA . Hansen Alpha 1-Antichymotrypsin Is Present in Diffuse Senile Plaques: A Comparative Study of 6-Protein and a1- Antichymotrypsin Immunostaining in the Alzheimer Brain Mikio Shoji, Shunsaku Hirai, Haruyasu Yamaguchi, Yasuo Harigaya, Koji Ishiguro, and Etsuro Matsubara February 1991 Rapid Communications Absence of bcl-2 Major Breakpoint Region and J,, Gene Rearrangement in Lymphocyte Predominance Hodgkin's Disease: Results of Southern Blot Analysis and Polymerase Chain Reaction Jonathan W. Said, Aaron F. Sassoon, I. Peter Shintaku, Paul J. Kurtin, and Geraldine S. Pinkus Binding of Tumor Necrosis Factor Alpha to Activated Forms of Human Plasma Aipha, Macroglobulin Gordon K. Wollenberg, Jonathan LaMarre, Soren Rosendal, Steven L. Gonias, and M. Anthony Hayes Hybridohistochemical Demonstration of Alternative Splicing of the CALC-| Gene M. Denijn, R. A. De Weger, C.J. M. Lips, J. A.M. Van Unnik, and W. Den Otter Detection of Loss of Heterozygosity in Formalin-fixed Paraffin-embedded Tumor Specimens by the Polymerase Chain Reaction Albert B. Bianchi, Nora M. Navone, and Claudio J. Conti Regular Articles Immunoreactivity of Anti-streptococcal Monoclonal Antibodies to Human Heart Valves: Evidence for Multiple Cross-reactive Epitopes James M. Gulizia, Madeleine W. Cunningham, and Bruce M. McManus Longitudinal Histopathologic Assessment of Rejection After Bladder-drained Canine Pancreas Allograft Transplantation R. D.M. Allen, J. M. Grierson, H. Ekberg, W.J. Hawthorne, P. Williamson, S. A. Deane, J. R. Chapman, G. J. Stewart, and J.-M. Little Platelet-Complement Interactions in Mesangial Proliferative “'ephritis in the Rat Richard J. Jobnson, Pam Pritzl, Hiroyuki lida, and Charles E. Alpers Juvenile Ceroid Lipofuscinosis: Evidence for Methylated Lysine in Neural Storage Body Protein Martin L. Katz and Merlyn Rodrigues Characterization of Preneoplastic and Neoplastic Lesions in the Rat Pancreas Daniel S. Longnecker, Olive S. Pettengill, Bruce H. Davis, Barbara K. Schaeffer, Joanne Zurlo, H. Lily Hong, and Elna T. Kublmann Ultrastructure of Respiratory Cilia of WIC-Hyd Male Rats: An Animal Model for Human Immotile Cilia Syndrome Chikao Torikata, Chuichi Kijimoto, and Masao Koto Induction of Different Morphologic Features of Malignant Melanoma and Pigmented Lesions After Transformation of Murine Melanocytes with bFGF-cDNA and H-ras, myc, neu, and E1a Oncogenes Santiago Ramon y Cajal, Saul Suster, Ruth Halaban, Ellen Filvaroff, and G. Paolo Dotto Immunohistochemical Localization and Quantification of the 3-(Cystein-S-yl)-acetaminophen Protein Adduct in Acetaminophen Hepatotoxicity Dean W. Roberts, Thomas J. Bucci, R. Wayne Benson, Alan R. Warbritton, Tammie A. McRae, Neil R. Pumford, and Jack A. Hinson Antibodies to Non-beta Regions of 'the Beta-amyloid Precursor Protein Detect a Subset of Senile Plaques Catharine Joachim, Dora Games, James Morris, Pamela Ward, Diana Frenkel, and Dennis Selkoe Vascular and Nonvascular Expression of INCAM-110: A Target for Mononuclear Leukocyte Adhesion in Normal and Inflamed Human Tissues G. Edgar Rice, J. Michael Munro, Christopher Corless, and Michael P. Bevilacqua In Vivo Biologic and Immunohistochemical Analysis of Interleukin-1 Alpha, Beta, and Tumor Necrosis Factor During Experimental Endotoxemia: Kinetics, Kupffer Cell Expression, and Glucocorticoid Effects Stephen W. Chensue, Pauline D. Terebub, Daniel G. Remick, Wendy E. Scales, and Steven L. Kunkel Systemic Amyloidosis in Transgenic Mice Carrying the Human Mutant Transthyretin (Met30) Gene: Pathologic Similarity to Human Familial Amyloidotic Polyneuropathy, Type | Shigehiro Yi, Kiyoshi Takahashi, Makoto Naito, Fumi Tashiro, Shoji Wakasugi, Shuichiro Maeda, Kazunori Shimada, Ken-ichi Yamamura, and Shukuro Araki Differential Expression of Basement Membrane Collagen Chains in Diabetic Nephropathy Youngki Kim, Mary M. Kleppel, Ralph Butkowski, S. Michael Mauer, Jorgen Wieslander, and Alfred F. Michael Human Immunodeficiency Virus-infected Multinucleated Histiocytes in Oropharyngeal Lymphoid Tissues from Two Asymptomatic Patients Aline Rinfret, Héléne Latendresse, René Lefebvre, Grégoire St-Louis, Paul Jolicoeur, and Louis Lamarre Enhanced Expression of Neural Cell Adhesion Molecules and Tenascin (Cytotactin) During Wound Healing Cheng-Ming Chuong and Hai-Ming Chen Methodologic Considerations Important in the Accurate Quantitation of Aortic Smooth Muscle Cell Replication in the Normal Rat Donna M. Lombardi, Michael A. Reidy, and Stephen M. Schwartz Tumor Necrosis Factor Induces Apoptosis (Programmed Cell Death) in Normal Endothelial Cells /n Vitro Bernard Robaye, Roger Mosselmans, Walter Fiers, Jacques E. Dumont, and Paul Galand Marker Profile of Different Phases in the Transition of Normal Human Ovarian Epithelium to Ovarian Carcinomas C.C. van Niekerk, O. C. Boerman, F. C. S. Ramaekers, and L. G. Poels Glomerular Basement Membrane Expansion in Passive Heymann Nephritis: Absence of Increased Synthesis of Type IV Collagen, Laminin, or Fibronectin Mitchell A. Fogel, Charles D. Boyd, Vijittra Leardkamolkarn, Dale R. Abrabamson, Andrew W. M. Minto, and David j. Salant Early Cellular Events in Evolving Cutaneous Delayed Hypersensitivity in Humans Heidi A. Waldorf, Laurence J. Walsh, Norman M. Schechter, and George F. Murphy Selective Differences in Macrophage Populations and Monokine Production in Resolving Pulmonary Granuloma and Fibrosis Irma Lemaire Detection of Coxsackievirus B3 RNA in Myocardial Tissues by the Polymerase Chain Reaction Lawrence M. Weiss, Lucile A. Movabed, Margaret E. Billingham, and Michael L. Cleary Keratin Subsets in Spindle Cell Sarcomas: Keratins Are Widespread But Synovial Sarcoma Contains a Distinctive Keratin Polypeptide Pattern and Desmoplakins Markku Miettinen ) March 1991 Rapid Communications Ovarian Granulosa—Stromal Cell Tumors Are Characterized by Trisomy 12 Jonathan A. Fletcher, Zenon Gibas, Kevin Donovan, Antonio Perez-Atayde, David Genest, Cynthia C. Morton, and Janice M. Lage The Intratracheal Administration of Endotoxin and Cytokines. Ill. The Interleukin-1 (IL-1) Receptor Antagonist Inhibits Endotoxin— and IL-1—Induced Acute Inflammation Thomas R. Ulich, Songmei Yin, Kaizhi Guo, Juan del Castillo, Stephen P. Eisenberg, and Robert C. Thompson Intercellular Adhesion Molecule-1 in Human Corneal Endothelium: Modulation and Function VictorM . Elner, Susan G. Elner, Mark A. Pavilack, Robert F. Todd III, Beatrice Y.]. T. Yue, and Andreas R. Huber Is Oncofetal Fibronectin a Trophoblast Glue for Human Implantation? Ronald F. Feinberg, Harvey J. Kliman, and Charles J.L ockwood Regular Articles Effects of the Phospholipase Inhibitor Mepacrine on Injury in Ischemic and Metabolically Inhibited Adult Isolated Myocytes Stephen C. Armstrong and Charles E. Ganote Development of Intrapancreatic Transplantable Mode! of Pancreatic Duct Adenocarcinoma in Syrian Golden Hamsters Hiroshi Egami, Tsutomu Tomioka, Margaret Tempero, David Kay, and Parviz M. Pour Cytomegalovirus Nucleic Acid Distribution Within the Human Vascular Tree M. G. R. Hendrix, M. Daemen, and C. A. Bruggeman Three-dimensional Cytoarchitecture of Normal and Atherosclerotic Intima of Human Aorta M.D. Rekbter, E. R. Andreeva, A. A. Mironov, and A. N. Orekhov Contrasting Roles for Tumor Necrosis Factor in the Pathogeneses of IgA and IgG Immune Complex Lung Injury Jeffrey S. Warren, PeterA .B arton, and Michael L. Jones BCL-1 Rearrangement: Frequency and Clinical Significance Among B-cell Chronic Lymphocytic Leukemias and Non-Hodgkin's Lymphomas Eleni Athan, Daniel R. Foitl, and Daniel M. Knowles Minimally Oxidized Low-density Lipoprotein Induces Tissue Factor Expression in Cultured Human Endothelial Celis Thomas A. Drake, Kambiz Hannani, Haihua Fei, Simon Lavi, and Judith A. Berliner Early Events in Liver Allograft Rejection: Delineation of Sites of Simultaneous Intragraft and Recipient Lymphoid Tissue Sensitization A.J. Demetris, S. Qian, H. Sun, J.J. Fung, A. Yagibashi, N. Murase, Y. Iwaki, B. Gambrell, and T. E. Starzl S-100 Protein Antibodies Do Not Label Normal Salivary Gland Myoepithelium: Histogenetic Implications for Salivary Gland Tumors Irving Dardick, Michael Stratis, William R. Parks, Franco G. DeNardi, and Harriette J. Kabn Platelet-derived Growth Factor-BB and Transforming Growth Factor Beta1 Selectively Modulate Glycosaminoglycans, Collagen, and Myofibroblasts in Excisional Wounds Glenn F. Pierce, Jerry Vande Berg, Ross Rudolph, John Tarpley, and Thomas A. Mustoe Evaluation of Hepatocellular Carcinoma Aggressiveness by a Panel of Extracellular Matrix Antigens Walter F. Grigioni, Spiridione Garbisa, Antonia D'Errico, Paola Baccarini, William G. Stetler-Stevenson, Lance A. Liotta, and Antonio M. Mancini Murine Retroviral Neurovirulence Correlates with an Enhanced Ability of Virus to Infect Selectively, Replicate in, and Activate Resident Microglial Cells T. V. Baszler and J. F. Zachary Epithelial Cells Immortalized by Human Papillomaviruses Have Premalignant Characteristics in Organotypic Culture Rebecca A. Blanton, Nuria Perez-Reyes, Daniel T. Merrick, and James K. McDougall Hairless Micropig Skin: A Novel Model for Studies of Cutaneous Biology Robert M. Lavker, Gang Dong, Peishu Zheng, and George F. Murphy Secondary Deposition of Beta Amyloid Within Extracellular Neurofibrillary Tangles in Alzheimer-type Dementia Haruyasu Yamaguchi, Yoichi Nakazato, Mikio Shoji, Koichi Okamoto, Yasuo Ihara, Mitsunori Morimatsu, and Shunsaku Hirai The Effects of Monocrotaline Pyrrole on Cultured Bovine Pulmonary Artery Endothelial and Smooth Muscle Cells J. F. Reindel and R. A. Roth Susceptibility to Coxsackievirus B3-induced Chronic Myocarditis Maps Near the Murine Tcra and Myhca Loci on Chromosome 14 Monica D. Traystman, Lawrence H. Chow, Bruce M. McManus, Abvie Herskowitz, Muriel N. Nesbitt, and Kirk W. Beisel Induction of Inflammatory Cell Infiltration and Necrosis in Normal Mouse Skin by the Combined Treatment of Tumor Necrosis Factor and Lithium Chloride Rudi Beyaert, Christian De Potter, Bart Vanhaesebroeck, Frans Van Roy, and Walter Fiers Expression of VLA-a2, VLA-a6, and VLA-B1 Chains in Normal Mucosa and Adenomas of the Colon, and in Colon Carcinomas and Their Liver Metastases Karin Koretz, Peter Schlag, Laurence Boumsell, and Peter Moller Basal Cell-specific and Hyperproliferation-related Keratins in Human Breast Cancer Ria H. W. Wetzels, Helma J. H. Kuijpers, E. Birgit Lane, Irene M. Leigh, Sergey M. Troyanovsky, Roland Holland, Urbain J. G. M. van Haelst, and Frans C. S. Ramaekers Cultured Human Atherosclerotic Plaque Smooth Muscle Cells Retain Transforming Potential and Display Enhanced Expression of the myc Protooncogene Joan Lee Parkes, Robert R. Cardell, Frank C. Hubbard, Jr., Dale Hubbard, Alan Meltzer, and Arthur Penn Animal Model! of Human Disease Experimental Myelocytic Leukemia in the Brown-Norway Rat as a Model for Pulmonary Leukostasis MarkA . van Buchem, Louisa P. Colly, Pancras C. W. Hogendoorn, Philip M. Kluin, and Roel Willemze April 1991 Rapid Communications Cingulin, a Specific Protein Component of Tight Junctions, Is Expressed in Normal and Neoplastic Human Epithelial Tissues Sandra Citi, Andrea Amorosi, Flavia Franconi, Alberto Giotti, and Giancarlo Zampi Human Coronary Transplantation-associated Arteriosclerosis: Evidence for a Chronic Immune Reaction to Activated Graft Endothelial Cells RobertN . Salomon, Christopher C. W. Hughes, Frederick J. Schoen, Douglas D. Payne, Jordan S. Pober, and Peter Libby Immunohistochemical Detection of P-Glycoprotein in Endometrial Adenocarcinoma ConstantineA . Axiotis, Carlos Monteagudo, Maria J. Merino, Noemi LaPorte, and Ronald D. Neumann p53 Expression in Colorectal Tumors ColinA .P urdie, Jane O'Grady, Juan Piris, Andrew H. Wyllie, and Colin C. Bird Alternative Splicing of Human VCAM-1 in Activated Vascular Endothelium Myron I. Cybulsky, Jochen W. U. Fries, Amy J.W illiams, Parvez Sultan, Vannessa M. Davis, Michael A. Gimbrone, Jr., and Tucker Collins The Rapid Detection of Clonal T-cell Proliferations in Patients with Lymphoid Disorders Keith P. McCarthy, Jobn P. Sloane, Janusz H. S. Kabarowski, Estela Matutes, and Leanne M. Wiedermann Inhibition of Angiogenesis /n Vitro by Arg-Gly-Asp—Containing Synthetic Peptides Roberto F. Nicosia and Elena Bonanno Regular Articles Oncogene Amplification in Breast Cancer Maryann Donovan-Peluso, Anna M. Contento, Hector Tobon, Benedetta Ripepi, and Joseph Locker Ozone Stress Initiates Acute Perturbations of Secreted Surfactant Membranes J. U. Balis, J. F. Paterson, J. M. Lundh, E. M. Haller, S. A. Shelley, and M. R. Montgomery Glomerular Mesangial Cell Migration: Response to Platelet Secretory Products Jeffrey L. Barnes and KarenA . Hevey Immunobiochemical and Molecular Biologic Characterization of the Cell Proliferation-associated Nuclear Antigen That Is Defined by Monoclonal Antibody Ki-67 Johannes Gerdes, Li Li, Carsten Schlueter, Michael Duchrow, Claudia Woblenberg, Christiane Gerlach, Ingrid Stabmer, Sabine Kloth, Ernst Brandt, and Hans-D. Flad Rosenthal Fibers Share Epitopes with «B-Crystallin, Glial Fibrillary Acidic Protein, and Ubiquitin, But Not with Vimentin: Immunoelectron Microscopy with Colloidal Gold Naoyuki Tomokane, Toru Iwaki, Jun Tateishi, Akiko Iwaki, and James E. Goldman Inhibition of Epithelial Cell Adhesion by Retinoic Acid: Relationship to Reduced Extracellular Matrix Production and Alterations in Ca** Levels James Varani, Douglas F. Gibbs, Dennis R. Inman, Biren Shah, Suzanne E. G. Fligiel, and John J. Voorhees Coexpression of Galanin and Adrenocorticotropic Hormone in Human Pituitary and Pituitary Adenomas Dora W. Hsu, Shing C. Hooi, E. Tessa Hedley-Whyte, Robert M. Strauss, and Lee M. Kaplan A Novel Chain of Basement Membrane-associated Collagen as Revealed by Biochemical and Immunohistochemical Characterizations of the Epitope Recognized by a Monoclonal Antibody Against Human Placenta Basement Membrane Collagen Jun Kino, Eijiro Adachi, Tsuyoshi Yoshida, Chinatsu Asamatsu, Keisuke Nakajima, Keiichi Yamamoto, and Toshibiko Hayashi Simian Immunodeficiency Virus Infection of Macaque Bone Marrow Macrophages Correlates with Disease Progression In Vivo Masanobu Kitagawa, AndrewA . Lackner, Dale J. Martfeld, Murray B. Gardner, and Satya Dandekar Cellular Events Associated with Inflammatory Angiogenesis in the Mouse Cornea Cord Sunderkétter, Waltraud Beil, Johannes Roth, and Clemens Sorg Age-related Decline in Prostacyclin Synthesis by Human Aortic Endothelial Cells: Qualitative and Quantitative Analysis Osamu Tokunaga, Takabiro Yamada, Jianglin Fan, and Teruo Watanabe Synthesis of IL-1 Alpha and IL-1 Beta by Arterial Cells in Atherosclerosis Carolyn F. Moyer, Dondin Sajuthi, Hermina Tulli, and J. Koudy Williams Expression of Neural Cell Adhesion Molecule in Normal and Neoplastic Human Neuroendocrine Tissues Long Jin, John J. Hemperly, and Ricardo V. Lloyd Inhibition of Mineralization of Glutaraldehyde-pretreated Bovine Pericardium by AICI,: Mechanisms and Comparisons with FeCl,, LaCl,, and Ga(NO3) in Rat Subdermal Model Studies Catherine L. Webb, Frederick J. Schoen, William E. Flowers, Allen C. Alfrey, Cynthia Horton, and Robert J. Levy Characterization of Target Injury of Murine Acute Graft-versus-host Disease Directed to Multiple Minor Histocompatibility Antigens Elicited by Either CD4* or CD8* Effector Cells George F. Murphy, Diana Whitaker, Jonathan Sprent, and Robert Korngold Interleukin-1B and Tumor Necrosis Factor-a Induce Gene Expression and Production of Leukocyte Chemotactic Factors, Colony-stimulating Factors, and Interleukin-6 in Human Mesangial Cells Carla Zoja, Ji Ming Wang, Stefania Bettoni, Marina Sironi, Daniela Renzi, Francesca Chiaffarino, Hanna E. Abboud, Jo Van Damme, Alberto Mantovani, Giuseppe Remuzzi, and Alessandro Rambaldi Interleukin-1 Gene Expression in Rabbit Vascular Tissue /n Vivo Steven K. Clinton, James C. Fleet, Harald Loppnow, Robert N. Salomon, Burton D. Clark, Joseph G. Cannon, Alan R. Shaw, CharlesA .D inarello, and Peter Libby Traffic of Peripheral B and T Lymphocytes to Hyperplastic, Preneoplastic Thymuses of AKR Mice SaraA .M ichie and Robert V. Rouse The Systemic Distribution of Epstein-Barr Virus Genomes in Fatal Post-transplantation Lymphoproliferative Disorders: An In Situ Hybridization Study Parmijeet S. Randhawa, Ronald Jaffe, Anthony Jake Demetris, Michael Nalesnik, Thomas E. Starzl, Yuan-Yuan Chen, and Lawrence M. Weiss Hepatocyte Growth Factor in Human Placenta and Trophoblastic Disease Helmut K. Wolf, Reza Zarnegar, Letealia Oliver, and George K. Michalopoulos Balloon Catheter De-endothelialization of the Nude Rat Carotid: Response to Injury in the Absence of Functional T Lymphocytes Gordon A. A. Ferns, Michael A. Reidy, and Russell Ross May 1991 Rapid Communications Urokinase-type Plasminogen Activator Is Expressed in Stromal Cells and Its Receptor in Cancer Cells at Invasive Foci in Human Colon Adenocarcinomas C. Pyke, P. Kristensen, E. Ralfkicer, J]. Grondabl-Hansen, J. Eriksen, F. Blasi, and K. Dano Immunohistochemical Localization of Granzyme B Antigen in Cytotoxic Cells in Human Tissues Arif Hameed, Luan D. Truong, Virginia Price, Olivier Krubenbubl, and Jurg Tschopp Lewy Bodies Are Immunoreactive with Antibodies Raised to Gelsolin Related Amyloid—Finnish Type Thomas Wisniewski, Matti Haltia, Jorge Ghiso, and Blas Frangione Identification of a Cell Membrane Protein That Binds Alveolar Surfactant David S. Strayer Intratracheal Injection of Endotoxin and Cytokines. Il. Interleukin-6 and Transforming Growth Factor Beta Inhibit Acute Inflammation Thomas R. Ulich, Songmei Yin, Kaizhi Guo, Eunhee S. Yi, Daniel Remick, and Juan del Castillo Regular Articles Importance of Viability and Attachment to an Ascites Tumor in the Release of Plasminogen Activator Qing Dong, Mubeng Zhou, Vadrevu Subbarao, and Chunghsin Ts'ao A Relationship Between Proteinuria and Acute Tubulointerstitial Disease in Rats with Experimental Nephrotic Syndrome Allison A. Eddy, Lorinda McCulloch, Elaine Liu, and Jennifer Adams Influence of the Site of Tumor Growth on the Capacity of a Low Tumorigenic Line of Friend Erythroleukemia Cells to Differentiate Ion Gresser, Jill Moss, David Woodrow, Caroline Le Bousse, Chantal Maury, Enrico Proietti, and Filippo Belardelli Neuronal and Glial Properties of a Murine Transgenic Retinoblastoma Model Tero Kivela, Ismo Virtanen, Dennis M. Marcus, Joan M. O'Brien, James L. Carpenter, Edgard Brauner, Abti Tarkkanen, and Daniel M. Albert Syphilis Superinfection Activates Expression of Human Immunodeficiency Virus | in Latently Infected Rabbits C.K. Tseng, M. A. Hughes, P.-L. Hsu, S. Mahoney, M. Duvic, and S. Sell Cell-cycle-Related Staining Patterns of Anti-proliferating Cell Nuclear Antigen Monoclonal Antibodies: Comparison with BrdUrd Labeling and Ki-67 Staining Jan Hein van Dierendonck, Jan H. Wijsman, Rob Keijzer, Cornelis J. H. van de Velde, and Cees J. Cornelisse Specific Binding of Human Low-density Lipoprotein to the Surface of Schistosomula of Schistosoma mansoni and Ingestion by the Parasite Maria W. Bennett and Jobn P. Caulfield Activation of Intraislet Lymphoid Cells Causes Destruction of Islet Cells Paul E. Lacy and Edward H. Finke The Role of Leukocytes in the Pathogenesis of Fibrin Deposition in Bovine Acute Lung Injury Bruce D. Car, M. Mitsu Suyemoto, Nancy R. Neilsen, and David O. Slauson Lineage-restricted Clonality in Biphasic Solid Tumors Jonathan A. Fletcher, Geraldine S. Pinkus, Noel Weidner, and Cynthia C. Morton Induction of HLA-DR Expression on Thyroid Follicular Cells by Cytomegalovirus Infection /n Vitro: Evidence for a Dual Mechanism of Induction Emilio L. Khoury, Lenore Pereira, and Francis S. Greenspan Quantitative Assessment of the Age of Fibrotic Lesions Using Polarized Light Microscopy and Digital Image Analysis J. Geoffrey Pickering and Derek R. Boughner Modulation of Alpha Smooth Muscle Actin and Desmin Expression in Perisinusoidal Cells of Normal and Diseased Human Livers A. Schmitt-Grdaiff, S. Kriiger, F. Bochard, G. Gabbiani, and H. Denk Loss of Antigens Associated with the Apical Endocytotic Pathway in Proximal Tubules from Rats with Heymann Nephritis E. J. Gutmann, J. L. Niles, R. T. McCluskey, and D. Brown The Roles of the Myofibroblast in Idiopathic Pulmonary Fibrosis: Ultrastructural and Immunohistochemical Features of Sites of Active Extracellular Matrix Synthesis Charles Kubn and Jobn A. McDonald Somatostatin Receptors in Differentiated Ovarian Tumors J.C. Reubi, U. Horisberger, J. G. M. Klijn, and j. A. Foekens Decrease in the AgNOR Number in Dunning R3327 Prostate Cancers After Treatment with an Agonist and Antagonist of Luteinizing Hormone-releasing Hormone Karoly Szepeshazi, Edib Korkut, and Andrew V. Schally Complement C4-derived Monocyte-directed Chemotaxis-inhibitory Factor: A Molecular Mechanism to Cause Polymorphonuclear Leukocyte-predominant Infiltration in Rheumatoid Arthritis Synovial Cavities Saburo Matsubara, Tetsuro Yamamoto, Takao Tsuruta, Katsumasa Takagi, and Takeshi Kambara June 1991 Rapid Communications Localization of Nuclear Matrix Proteins (NMPs) in Multiple Tissue Types with NM-200.4@ (An Antibody Strongly Reactive with NMPs Found in Breast Carcinoma) Noel Weidner, David S. Weinberg, Sarab C. Hardy, KatherineA . Hollister, and Grabam P. Lidgard Interleukin-1 mRNA-expressing Macrophages in Human Chronically Inflamed Gingival Tissues Y. Matsuki, T. Yamamoto, and K Hara The Eosinophil as a Cellular Source of Transforming Growth Factor Alpha in Healing Cutaneous Wounds Randy Todd, Bruce R.D onoff, Tao Chiang, Ming Yung Chou, Aram Elovic, George T. Gailagher, and David T. W. Wong Interleukin-4 Induces the Synthesis and Secretion of MCP-1/JE by Human Endothelial Cells Barrett J. Rollins and Jordan S. Pober Regular Articles islet Amyloid Polypeptide in Proliferating Pancreatic B Cells During Development, Hyperplasia, and Neoplasia in Humans and Mice Guido Rindi, Giorgio Terenghi, Gunilla Westermark, Per Westermark, Gonzalo Moscoso, and JuliaM . Polak Differential Expression of Markers for Endothelial Cells, Pericytes, and Basal Lamina in the Microvasculature of Tumors and Granulation Tissue R. O. Schlingemann, F. J. R. Rietveld, F. Kwaspen, P. C. M. van de Kerkhof, R. M. W. de Waal, and D. J. Ruiter In Vitro Analysis of Extracellular Matrix Production by Porcine Glomerular Mesangial and Vascular Smooth Muscle Cells Yung-Yen Chiang, Shigeo Takebayashi, and Terry D. Oberley Evidence for In Vivo Degradation of C3a Anaphylatoxin by Mast Cell Chymase: |. Nonspecific Activation of Rat Peritoneal Mast Cells by C3aqe arg Toshiyuki Kajita and TonyE .H ugli Proliferation of Normal Breast Epithelial Cells as Shown by /n Vivo Labeling with Bromodeoxyuridine Konstantin Christov, KarenL .C hew, Britt-Marie Ljung, FredericM .W aldman, LeeAnn Duarte, WilliamH . Goodson III, HeleneS . Smith, and Brian H. Mayall X-Linked Lymphoreticular Disease in the Scurfy (sf) Mutant Mouse VirginiaL . Godfrey, J. E.W ilkinson, and Liane B. Russell Lymphomas of True Histiocytic Origin: Expression of Different Phenotypes in So-called True Histiocytic Lymphoma and Malignant Histiocytosis Su Ming Hsu, Yat-Sen Ho, and Pei-Ling Hsu Pneumonitis Associated with Coinfection by Human Herpesvirus 6 and Legionella in an immunocompetent Adult Susan K Russler, MarkA . Tapper, Konstance K Knox, Andrejs Liepins, and DonaldR . Carrigan Cytokeratin Expression and Vimentin Content in Large Cell Anaplastic Lymphomas and Other Non-Hodgkin's Lymphomas C. Gustmann, M. Altmannsberger, M. Osborn, H. Griesser, and A. C. Feller