T H E Alzheimer’s Prevention Program This page is intentionally blank T H E Alzheimer’s Prevention Program Keep Your Brain Healthy for the Rest of Your Life GA RY S M A L L, M.D. DIRECTOR OF THE UCLA LONGEVITY CENTER & G IGI VORGAN AU T H O R S O F T H E M E M O RY B I B L E WO R K M A N P U B L I S H I N G • N E W YO R K Copyright © 2011, 2012 by Gary Small, M.D., and Gigi Vorgan Design copyright © by Workman Publishing Photo copyright © by Gary Small, M.D. Drawing of the woman’s profile with the brain, courtesy of Diana Jacobs. Photos of older senile brain and younger healthy brain courtesy of Harry Vinters, M.D. Beatles photograph United Press International, 1964 All rights reserved. No portion of this book may be reproduced— mechanically, electronically, or by any other means, including photocopying— without written permission of the publisher. Published simultaneously in Canada by Thomas Allen & Son, Limited. The Library of Congress has cataloged the hardcover edition as follows: Small, Gary W. The alzheimer’s prevention program : keep your brain healthy for the rest of your life / Gary Small, Gigi Vorgan. p. cm. ISBN 978-0-7611-6526-2 (hardback) 1. Alzheimer’s disease--Prevention--Popular works. 2. Alzheimer’s disease--Nutritional aspects-- Popular works. 3. Alzheimer’s disease--Physiological aspects--Popular works. I. Vorgan, Gigi, 1958- II. Title. RC523.2.S62 2012 616.8'31--dc23 2011025462 ISBN 978-0-7611-7222-2 (paperback) Design by Lisa Hollander As with any adjustment to your diet or exercise regimen, consult your doctor before implementing changes. Workman will not be liable for any complications, injuries, loss, or other medical problems arising from or in connection to this book. Workman books are available at special discounts when purchased in bulk for premiums and sales promotions as well as for fund-raising or educational use. 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Printed in the United States of America First paperback printing November 2012 10 9 8 7 6 5 4 3 2 1 Contents ACKNOWLEDGMENTS........................................................ vii PREFACE........................................................................ ix CHAPTER 1: Prevention Is Today’s Best Defense ..................................1 CHAPTER 2: Where You Stand Now ................................................. 29 CHAPTER 3: Strengthening Memory Skills ........................................ 45 CHAPTER 4: Physical Exercise Protects the Brain ................................. 67 CHAPTER 5: Healthy Brain Nutrition ................................................. 87 CHAPTER 6: Mental Workouts to Sharpen Your Mind .........................109 CHAPTER 7: Reduce Stress to Fortify Neurons ....................................137 CHAPTER 8: Latest on Health Care and Medicine ................................155 CHAPTER 9: Your First Seven Days ....................................................177 CHAPTER 10: Protecting Your Brain for Life .........................................223 BONUS CHAPTER: New Resources .............................................................237 APPENDICES: 1..PROGRESS.CHARTS....................................................250 2..ADDITIONAL.RESOURCES............................................252 3..NOTES.AND.SCIENTIFIC.REFERENCES.............................256 LIST.OF.ABBREVIATIONS................................................275 INDEX........................................................................... 278 This page is intentionally blank Acknowledgments We are grateful to the volunteers and patients who participated in the many research studies that inspired this book. We also thank Diana Jacobs for her drawing of the human brain, Prabha Siddarth for her statistical input, our tireless and creative publicists Selina Meere and Courtney Greenhalgh, and our colleagues and friends who pro- vided their guidance and input, including Susan Bowerman, Rachel Champeau, Mindy Gandin, Dr. Rob Gandin, Dr. David Heber, Jeffrey Nemerovsky, and Don Seigel. We are eternally thankful to our longtime agent and dear friend, Sandy Dijkstra, who has inspired our writing for many years; our talented publisher, Bob Miller; our gifted chief editor, Susan Bolotin; and our longtime friend and extraordinary editor, Mary Ellen O’Neill. This book would not have been possible without the love and support of our parents, Gertrude and Dr. Max Small and Rose and Fred Weiss, and our children, Rachel and Harry. NOTE:.The stories contained in this book are composite accounts based on the experiences of many individuals and do not represent any one person or group of people. Similarities to actual persons are coincidental and unintentional. Readers may wish to consult with their physician before initiating any diet or exercise program. vii This page is intentionally blank Preface For decades, researchers have been searching for a way to cure Alzheimer’s disease, by far the most common cause of age-related mental decline. Despite considerable progress, no miracle remedy has yet been discovered. But we don’t need to sit and wait for a remarkable new drug or vaccine to come along before we start protecting our brains from this devastating disease. The Alzheimer’s Prevention Program offers strate- gies to help delay symptoms from emerging. The scientific evidence points to prevention as today’s most effective way to defend against Alzheimer’s. If we can stave off the onset of dementia long enough for people never to experience symptoms in their lifetime—that in itself could be considered a cure. Genetics accounts for only part of the risk for Alzheimer’s dis- ease, and we now know that lifestyle choices have a tremendous impact. A lifestyle that promotes brain health not only strengthens neurons and postpones mental decline, it also improves memory ability and brain efficiency right away. No matter where you are in your health profile—even if you exercise every day and eat all the right foods to keep your body and brain healthy—this program will still help you feel better and delay Alzheimer’s disease longer. Whether you’re a student, thirty-something, baby boomer, or senior, you will benefit quickly from practicing Alzheimer’s prevention strategies—and you’ll have fun doing it. It’s never too early or too late to start protecting your brain. The Alzheimer’s Prevention Program will show you how to get your brain healthy and do all you can to keep it that way for the rest of your life. gary small, m.d., and gigi vorgan los angeles, california, january 2012 ix
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