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The Alzheimer's Answer: Reduce Your Risk and Keep Your Brain Healthy PDF

320 Pages·2008·1.85 MB·english
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ffirs.qxp 12/4/07 2:03 PM Page iii The Alzheimer’s Answer Reduce Your Risk and Keep Your Brain Healthy MARWAN NOEL SABBAGH, MD Director, the Cleo Roberts Center for Clinical Research Sun Health Research Institute John Wiley & Sons, Inc. ffirs.qxp 12/4/07 2:03 PM Page ii ffirs.qxp 12/4/07 2:03 PM Page i The Alzheimer’s Answer ffirs.qxp 12/4/07 2:03 PM Page ii ffirs.qxp 12/4/07 2:03 PM Page iii The Alzheimer’s Answer Reduce Your Risk and Keep Your Brain Healthy MARWAN NOEL SABBAGH, MD Director, the Cleo Roberts Center for Clinical Research Sun Health Research Institute John Wiley & Sons, Inc. ffirs.qxp 12/4/07 2:03 PM Page iv Copyright © 2008 by Marwan Noel Sabbagh, M.D. All rights reserved Published by John Wiley & Sons, Inc., Hoboken, New Jersey Published simultaneously in Canada Illustration credits: pages 36, 37, 39, 246, courtesy of the NIA, www.nia.nih.gov/Alzheimers/ Resources; pages 38, 41 (top), provided by Dr. Thomas Beach of Sun Health Research Institute; page 41 (bottom), provided by Athena diagnostics with permission; page 51, courtesy of the NIA 2004–2005 Alzheimer’s disease progress report; pages 100, 102, Drs. Alex Roher and Thomas Beach of Sun Health Research Institute. The Alzheimer’s Questionnaire on page 239 is courtesy of the Sun Health Research Institute. Design and composition by Navta Associates, Inc. No part of this publication may be reproduced, stored in a retrieval system, or transmit- ted in any form or by any means, electronic, mechanical, photocopying, recording, scanning, or otherwise, except as permitted under Section 107 or 108 of the 1976 United States Copyright Act, without either the prior written permission of the Publisher, or authorization through payment of the appropriate per-copy fee to the Copyright Clear- ance Center, 222 Rosewood Drive, Danvers, MA 01923, (978) 750–8400, fax (978) 646–8600, or on the web at www.copyright.com. Requests to the Publisher for permis- sion should be addressed to the Permissions Department, John Wiley & Sons, Inc., 111 River Street, Hoboken, NJ 07030, (201) 748–6011, fax (201) 748–6008, or online at http://www.wiley.com/go/permissions. The information contained in this book is not intended to serve as a replacement for pro- fessional medical advice. Any use of the information in this book is at the reader’s discre- tion. The author and the publisher specifically disclaim any and all liability arising directly or indirectly from the use or application of any information contained in this book. A health care professional should be consulted regarding your specific situation. For general information about our other products and services, please contact our Cus- tomer Care Department within the United States at (800) 762–2974, outside the United States at (317) 572–3993 or fax (317) 572–4002. Wiley also publishes its books in a variety of electronic formats. Some content that appears in print may not be available in electronic books. For more information about Wiley products, visit our web site at www.wiley.com. Library of Congress Cataloging-in-Publication Data: Sabbagh, Marwan Noel. The Alzheimer's answer : reduce your risk and keep your brain healthy / Marwan Noel Sabbagh ; foreword by Justice Sandra Day O'Connor. p. cm. Includes bibliographical references and index. ISBN 978-0-470-04494-0 (cloth) 1. Alzheimer's disease--Prevention--Popular works. 2. Self-care, Health--Popular works. I. Title. RC523.2.S23 2008 616.8'3105--dc22 2007044823 Printed in the United States of America 10 9 8 7 6 5 4 3 2 1 ffirs.qxp 12/4/07 2:03 PM Page v To my beloved wife, Ida, who inspires me. ffirs.qxp 12/4/07 2:03 PM Page vi ftoc.qxp 12/4/07 2:04 PM Page vii Contents Foreword by Justice Sandra Day O’Connor ix Acknowledgments xi Introduction 1 PART I Preventing Alzheimer’s 1 Alzheimer’s Disease 9 2 Alzheimer’s and the Brain 35 3 Is Preventing Alzheimer’s Disease Really Possible? 45 PART II Real Risks 4 Your Alzheimer’s IQ: Know Your Risk 61 5 Diabetes 81 6 Body Weight and Obesity 88 7 Stroke, Cerebrovascular Disease, and Heart Disease 98 8 Cognitive Killers 107 9 Blood Pressure and Hypertension 122 10 Estrogen and Hormone Replacement Therapy 130 vii ftoc.qxp 12/4/07 2:04 PM Page viii viii CONTENTS PART III Real Recommendations 11 Eating Your Way out of Alzheimer’s 139 12 Red Wine and Other Alcoholic Beverages 156 13 Managing Your Cholesterol and Lipids 164 14 Exercising Your Way toward Prevention 175 15 Staying Sharp with Mental Exercises 182 16 Anti-inflammatories and Alzheimer’s 191 17 Vitamins May Protect 198 18 Supplements: Real Hope or Empty Promises? 212 PART IV If You Have Alzheimer’s Disease 19 Get Help: Alzheimer’s Is Treatable 237 20 The Future of Alzheimer’s Disease 255 References 267 Index 299

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