Textbook of Medical Psychiatry

763 Pages·2020·7.026 MB·English

by  Edited by Paul Summergrad, and John Querques, Paul Summergrad (editor), John Querques (editor)

“Finally, a resource that lucidly describes medical diseases that cause psychiatric symptoms, and psychiatric
T E X T B O O K o f
diseases that cause physical ailments. The discussion of the overlap between these is the best I have read and
will serve as a resource for psychiatrists, neurologists, and generalists for some time to come.”
Allan H. Ropper, M.D., Professor of Neurology, Harvard Medical School; Executive Vice Chair, Department of
Neurology, Brigham and Women’s Hospital
MEDICAL
M
“Medical illness can mimic or cause all sorts of psychiatric problems and vice versa. The fi rst step in every dif-
ferential diagnosis in psychiatry must be to rule out medical illness.… This vital book…should become required
reading for all medical students. It has my highest recommendation.”
E
Allen Frances, M.D., Professor & Chair Emeritus, Department of Psychiatry, Duke University; Chair, DSM-IV Task
D
Force; Author, Saving Normal
PSYCHIATRY
“Combined or co-occurring medical and psychiatric illnesses are critically important in both general and spe- I
cialty medical care. Through case examples, developing a differential diagnosis and clinical reasoning, and C
reviewing the evidence-based approaches for management and treatment, this textbook will be the standard
in the fi eld. It is a major and signifi cant contribution.” A T
E
Michelle B. Riba, M.D., M.S., Professor and Associate Director, University of Michigan Comprehensive Depression
L X
Center; and Director, PsychOncology Program, University of Michigan Rogel Cancer Center
T


P B
The Textbook of Medical Psychiatry focuses on medical disorders that can directly cause or affect the clinical O
presentation and course of psychiatric disorders. Clinicians who work primarily in psychiatric settings, as S
well as those who practice in medical settings but who have patients with co-occurring medical and psychiatric O
Y
illnesses or symptoms, can benefi t from a careful consideration of the medical causes of psychiatric illnesses.
The editors, authorities in the fi eld, have taken great care both in selecting the book’s contributors, who are K
C
content and clinical experts, and in structuring the book for maximum learning and usefulness.
Even veteran clinicians may fi nd it challenging to diagnose and treat patients who have co-occurring H o
medical and psychiatric disorders or symptoms. The comprehensive knowledge base and clinical wisdom
f
contained in the Textbook of Medical Psychiatry make it the go-to resource for evaluating and managing these
I
diffi cult cases.
A

Paul Summergrad, M.D., is Dr. Frances S. Arkin Professor and Chairman of the Department of Psychiatry, and T
Professor of Psychiatry and Medicine, at Tufts University School of Medicine, as well as Psychiatrist-in-Chief
R
of Tufts Medical Center, in Boston, Massachusetts.
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David A. Silbersweig, M.D., is Stanley Cobb Professor of Psychiatry at Harvard Medical School and Chairman
of the Department of Psychiatry, as well as Co-Director of the Center for the Neurosciences at Brigham and
Women’s Hospital in Boston, Massachusetts.
Philip R. Muskin, M.D., M.A., is Professor of Psychiatry and Senior Consultant in Consultation-Liaison Psychiatry
Summergrad
at Columbia University Medical Center, in the Department of Psychiatry at Columbia University Vagelos Col-
lege of Physicians and Surgeons in New York, New York. Silbersweig
John Querques, M.D., is Vice Chairman for Hospital Services in the Department of Psychiatry at Tufts Medical Muskin
Center and Associate Professor of Psychiatry at Tufts University School of Medicine in Boston, Massachusetts.
Querques
ISBN 978-1-61537-080-1 EDITED BY
90000
Paul Summergrad, M.D.
David A. Silbersweig, M.D.
Philip R. Muskin, M.D., M.A.
9 781615 370801
Cover design: Susan Westrate John Querques, M.D.
Cover image: © maximmmmum, Shutterstock.com
TEXTBOOK of
MEDICAL
PSYCHIATRY
TEXTBOOK of
MEDICAL
PSYCHIATRY
EDITED BY
Paul Summergrad, M.D.
David A. Silbersweig, M.D.
Philip R. Muskin, M.D., M.A.
John Querques, M.D.
Note: The authors have worked to ensure that all information in this book is accurate at the time of pub-
lication and consistent with general psychiatric and medical standards, and that information concerning
drug dosages, schedules, and routes of administration is accurate at the time of publication and consis-
tent with standards set by the U.S. Food and Drug Administration and the general medical community.
As medical research and practice continue to advance, however, therapeutic standards may change.
Moreover, specific situations may require a specific therapeutic response not included in this book. For
these reasons and because human and mechanical errors sometimes occur, we recommend that readers
follow the advice of physicians directly involved in their care or the care of a member of their family.
Books published by American Psychiatric Association Publishing represent the findings, conclusions,
and views of the individual authors and do not necessarily represent the policies and opinions of Amer-
ican Psychiatric Association Publishing or the American Psychiatric Association.
If you wish to buy 50 or more copies of the same title, please go to www.appi.org/specialdiscounts for
more information.
Copyright © 2020 American Psychiatric Association Publishing
ALL RIGHTS RESERVED
First Edition
Manufactured in the United States of America on acid-free paper
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American Psychiatric Association Publishing
800 Maine Avenue SW
Suite 900
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www.appi.org
Library of Congress Cataloging-in-Publication Data
Names: Summergrad, Paul, editor. | Silbersweig, David, editor. | Muskin, Philip R., editor. |
Querques, John, 1970– editor. | American Psychiatric Association Publishing, issuing body.
Title: Textbook of medical psychiatry / edited by Paul Summergrad, David A. Silbersweig, Philip R.
Muskin, John Querques.
Description: First edition. | Washington, DC : American Psychiatric Association Publishing, [2020] |
Includes bibliographical references and index. | Summary: “The Textbook of Medical Psychiatry
focuses on medical disorders that can directly cause or affect the clinical presentation and course of
psychiatric disorders. Clinicians who work primarily in psychiatric settings, as well as those who
practice in medical settings but who have patients with co-occurring medical and psychiatric illnesses
or symptoms, can benefit from a careful consideration of the medical causes of psychiatric illnesses.
The editors, authorities in the field, have taken great care both in selecting the book's contributors,
who are content and clinical experts, and in structuring the book for maximum learning and
usefulness. The first section presents a review of approaches to diagnosis, including medical,
neurological, imaging, and laboratory examination and testing. The second section provides a tour of
medical disorders that can cause psychiatric symptoms or disorders, organized by medical disease
category. The third section adopts the same format as the second, offering a review of psychiatric
disorders that can be caused or exacerbated by medical disorders, organized by psychiatric disorder
types. The final section contains chapters on conditions that fall at the boundary between medicine
and psychiatry. Even veteran clinicians may find it challenging to diagnose and treat patients who
have co-occurring medical and psychiatric disorders or symptoms. The comprehensive knowledge
base and clinical wisdom contained in the Textbook of Medical Psychiatry makes it the go-to resource
for evaluating and managing these difficult cases”—Provided by publisher.
Identifiers: LCCN 2019055530 (print) | LCCN 2019055531 (ebook) | ISBN 9781615370801 (hardcover ;
alk. paper) | ISBN 9781615372829 (ebook)
Subjects: MESH: Mental Disorders | Comorbidity
Classification: LCC RC467 (print) | LCC RC467 (ebook) | NLM WM 140 | DDC
616.89—dc23
LC record available at https://lccn.loc.gov/2019055530
LC ebook record available at https://lccn.loc.gov/2019055531
British Library Cataloguing in Publication Data
A CIP record is available from the British Library.
Dedications
For Randy, Sophie, and Michael—For all the many reasons why.
Paul Summergrad
For Emily Stern, my partner in all things, with love and respect.
David A. Silbersweig
For Catherine, Matthew, and Marlene, who are my inspirations,
and for Cecilia, who has wonderfully changed the direction of my life.
Philip R. Muskin
For Mom and Dad, with love.
John Querques
Contents
Contributors . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .xiii
Foreword . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .xxi
Professor Sir Simon Wessely
Introduction: The Importance of
Medical–Psychiatric Illness . . . . . . . . . . . . . . . . . . xxv
Paul Summergrad, M.D.
David A. Silbersweig, M.D.
Philip R. Muskin, M.D., M.A.
John Querques, M.D.
PART I
Approach to the Patient
1
An Internist’s Approach to the
Neuropsychiatric Patient . . . . . . . . . . . . . . . . . . . . . .3
Joseph Rencic, M.D.
Deeb Salem, M.D.
2
The Neurological Examination for
Neuropsychiatric Assessment . . . . . . . . . . . . . . . . .15
Sheldon Benjamin, M.D.
Margo D. Lauterbach, M.D.
3
The Bedside Cognitive Examination
in Medical Psychiatry . . . . . . . . . . . . . . . . . . . . . . . .31
Sean P. Glass, M.D.
4
Neuroimaging, Electroencephalography, and
Lumbar Puncture in Medical Psychiatry. . . . . . . . . .51
Daniel Talmasov, M.D.
Joshua P. Klein, M.D., Ph.D.
5
Toxicological Exposures and Nutritional
Deficiencies in the Psychiatric Patient . . . . . . . . . . .85
Mira Zein, M.D., M.P.H.
Sharmin Khan, M.D.
Jaswinder Legha, M.D., M.P.H.
Lloyd Wasserman, M.D.
PART II
Psychiatric Considerations
in Medical Disorders
6
Cardiovascular Disease . . . . . . . . . . . . . . . . . . . . .175
Peter A. Shapiro, M.D.
7
Endocrine Disorders and Their Psychiatric
Manifestations . . . . . . . . . . . . . . . . . . . . . . . . . . . .193
Jane P. Gagliardi, M.D., M.H.S., FACP, DFAPA
8
Inflammatory Diseases and Their
Psychiatric Manifestations . . . . . . . . . . . . . . . . . . .229
Rolando L. Gonzalez, M.D.
Charles B. Nemeroff, M.D., Ph.D.
9
Infectious Diseases and Their Psychiatric
Manifestations . . . . . . . . . . . . . . . . . . . . . . . . . . . .265
Oliver Freudenreich, M.D.
Kevin M. Donnelly-Boylen, M.D.
Rajesh T. Gandhi, M.D.
10
Gastroenterological Disease in Patients
With Psychiatric Disorders. . . . . . . . . . . . . . . . . . .289
Ash Nadkarni, M.D.
David A. Silbersweig, M.D.
11
Renal Disease in Patients With Psychiatric
Illness. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .319
Lily Chan, M.D.
J. Michael Bostwick, M.D.
12
Neurological Conditions and Their Psychiatric
Manifestations . . . . . . . . . . . . . . . . . . . . . . . . . . . .339
Barry S. Fogel, M.D.
Gaston C. Baslet, M.D.
Laura T. Safar, M.D.
Geoffrey S. Raynor, M.D.
David A. Silbersweig, M.D.
13
Cancer: Psychiatric Care of the
Oncology Patient . . . . . . . . . . . . . . . . . . . . . . . . . .397
Carlos G. Fernandez-Robles, M.D., M.B.A.
Sean P. Glass, M.D.
14
Dermatology: Psychiatric Considerations
in the Medical Setting. . . . . . . . . . . . . . . . . . . . . . .419
Katherine Taylor, M.D.
Janna Gordon-Elliott, M.D.
Philip R. Muskin, M.D., M.A.
15
Women’s Mental Health and Reproductive
Psychiatry. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .447
Marcela Almeida, M.D.
Kara Brown, M.D.
Leena Mittal, M.D.
Margo Nathan, M.D.
Hadine Joffe, M.D., M.Sc.
PART III
Medical Considerations in
Psychiatric Disorders
16
Neurodevelopmental Disorders . . . . . . . . . . . . . . .481
Aaron Hauptman, M.D.
Sheldon Benjamin, M.D.
17
Psychotic Disorders Due to Medical Illnesses . . . .499
Hannah E. Brown, M.D.
Shibani Mukerji, M.D., Ph.D.
Oliver Freudenreich, M.D.
18
Catatonia in the Medically Ill Patient . . . . . . . . . . .523
Scott R. Beach, M.D.
Gregory L. Fricchione, M.D.
19
Mood Disorders Due to Medical Illnesses . . . . . . .541
Sivan Mauer, M.D., M.S.
John Querques, M.D.
Paul Summergrad, M.D.
20
Anxiety and Related Disorders: Manifestations
in the General Medical Setting. . . . . . . . . . . . . . . .563
Charles Hebert, M.D.
David Banayan, M.D., M.Sc., FRCPC
Fernando Espi-Forcen, M.D., Ph.D.
Kathryn Perticone, A.P.N., M.S.W.
Sameera Guttikonda, M.D.
Mark Pollack, M.D.
21
Substance Use Disorders in the Medical Setting. .587
Samata R. Sharma, M.D.
Saria El Haddad, M.D.
Joji Suzuki, M.D.
22
Neurocognitive Disorders. . . . . . . . . . . . . . . . . . . .629
Flannery Merideth, M.D.
Ipsit V. Vahia, M.D.
Dilip V. Jeste, M.D.
PART IV
Conditions and Syndromes
at the Medical–Psychiatric Boundary
23
Chronic Pain. . . . . . . . . . . . . . . . . . . . . . . . . . . . . .651
Robert M. McCarron, D.O.
Samir J. Sheth, M.D.
Charles De Mesa, D.O., M.P.H.
Michelle Burke Parish, Ph.D., M.A.
24
Insomnia . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .663
Karl Doghramji, M.D.
25
Somatic Symptom and Related Disorders. . . . . . .677
Anna L. Dickerman, M.D.
Philip R. Muskin, M.D., M.A.
Index . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .697