Taurine 7 PDF
Preview Taurine 7
Taurine 7 Advances in Experimental Medicine and Biology EditorialBoard: NathanBack,StateUniversityofNewYorkatBuffalo IrunR.Cohen,TheWeizmannInstituteofScience AbelLajtha,N.S.,KlineInstituteforPsychiatricResearch JohnD.Lambris,UniversityofPennsylvania RodolfoPaoletti,UniversityofMilan RecentVolumesinthisSeries Volume635 GIMICROBIOTAANDREGULATIONOFTHEIMMUNESYSTEM EditedbyGaryB.HuffnagleandMairiNoverr Volume636 MOLECULARMECHANISMSINSPERMATOGENESIS EditedbyC.YanCheng Volume637 MOLECULARMECHANISMSINXERODERMAPIGMENTOSUM EditedbyShaminAhmadandFumioHanaoka Volume638 SOMITOGENESIS EditedbyMiguelMarotoandNeilWhittock Volume639 BREASTFEEDING:EARLYINFLUENCESONLATERHEALTH EditedbyGailGoldberg Volume640 MULTICHAINIMMUNERECOGNITIONRECEPTORSIGNALING EditedbyAlexanderSigalov Volume641 CELLULAROSCILLATORYMECHANISMS EditedbyMiguelMarotoandNickMonk Volume642 THESARCOMEREANDSKELETALMUSCLEDISEASE EditedbyNigelG.Laing Volume643 TAURINE7 EditedbyJunichiAzuma,StephenW.Schaffer,andTakashiIto AContinuationOrderPlanisavailableforthisseries.Acontinuationorderwillbringdeliveryofeach newvolumeimmediatelyuponpublication.Volumesarebilledonlyuponactualshipment.Forfurther informationpleasecontactthepublisher. · · Junichi Azuma Stephen W. Schaffer Takashi Ito Editors Taurine 7 123 Editors Dr.JunichiAzuma Dr.StephenW.Schaffer OsakaUniversity CollegeofMedicine DepartmentClinicalEvaluation UniversityofSouthAlabama ofMedicinesandTherapeutics DepartmentofPharmacology 1–6YamadaOka,Suita 307Universityblvd.,Mobile,Alabama Osaka 36688USA 565-0871Japan [email protected] [email protected] Dr.TakashiIto CollegeofMedicine UniversityofSouthAlabama DepartmentofPharmacology 307Universityblvd.,Mobile,Alabama 36688USA [email protected] ISBN:978-0-387-75680-6 e-ISBN:978-0-387-75681-3 DOI:10.1007/978-0-387-75681-3 LibraryofCongressControlNumber:2008937801 (cid:2)c SpringerScience+BusinessMedia,LLC2009 Allrightsreserved.Thisworkmaynotbetranslatedorcopiedinwholeorinpartwithoutthewritten permission of the publisher (Springer Science+Business Media, LLC, 233 Spring Street, New York, NY10013,USA),exceptforbriefexcerptsinconnectionwithreviewsorscholarlyanalysis.Usein connectionwithanyformofinformationstorageandretrieval,electronicadaptation,computersoftware, orbysimilarordissimilarmethodologynowknownorhereafterdevelopedisforbidden. Theuseinthispublicationoftradenames,trademarks,servicemarks,andsimilarterms,eveniftheyare notidentifiedassuch,isnottobetakenasanexpressionofopinionastowhetherornottheyaresubjectto proprietaryrights. Printedonacid-freepaper springer.com Preface Taurine(2-ethanesulfonicacid)isauniqueandmysteriouscompound.Itispresent in relatively high concentrations in a wide range of cells and tissues, but exists as afreeaminoacidinthesecellswithoutbeingutilizedinproteinsynthesis.Taurine wasfirstisolatedmorethan150yearsagofromox(Taurus)bile,whereitwasfound inconjugationwithbileacidsthroughanamidelinkage.Sincethattime,ithasbeen reported to exist in particularly high concentrations in the cytoplasm of excitable tissues,suchascertainpartsofthebrain,retina,skeletalmuscle,myocardiumand platelets. Some of its physiological functions have already been established, for exampleitsroleasanessentialnutrientduringdevelopment,anosmolyteandaneu- romodulator.Recently,taurinehasbeenadvancedasacytoprotectiveagentagainst certain pathological perturbations, but the mechanisms underlying its actions are stillmostlyamatterofspeculation.Moreover,itispossiblethatotherputativefunc- tionsoftaurineremaintobediscovered. The16thInternationalTaurineMeeting“TaurineforFutureHealthcare”washeld onSeptember2–5,2007,inShimoda,Shizuoka,Japan,withthesiteofthemeeting being the Shimoda Central Hotel. Approximately 80 individuals from 11 nations, including newcomers as well as experts in taurine research, attended the scientific meeting.Atotalof79paperswerepresentedaseitheroralorposterpresentations. This meeting was multidisciplinary, with participants addressing multiple areas of thebiologicalsciences.Typhoon“Fitow”,whichmeans“beautifulfragrantflower” inaMicronesianlanguage,hittheShimodaregionwithfullforceattheendofthe meeting, but we were able to finish the scientific sessions and enjoy an excursion priortotheonslaught.ThemorningafterFitow’sfury,thelingeringscentofflowers remindedusthatweareclearlyatthedawnofaneweraintaurineresearch. TheorganizersofthetaurinemeetingwouldliketothankTaishoPharmaceutical Co., Ltd., Tokyo, Japan, for their generous financial support and assistance in the organization of the meeting. We would also like to thank Dong-A Pharmaceutical Co,Korea,fortheirgenerousfinancialsupport.Inaddition,wewouldliketothank all participants of the meeting, especially the participants from the Osaka Univer- sity and Taisho Pharmaceutical Company. The staff of the Shimoda Central Hotel wasextremelyhelpfulinmakingsurethatallparticipantswerecomfortableandfor ensuringthesuccessoftheirplannedevents.Finally,wewouldliketoexpressour v vi Preface appreciationfortheuntiringeffortbefore,duringandafterthescientificsessionsof Dr.Abe,whohelpedensurethesuccessofthemeeting. We are pleased to provide you with Taurine 7, which contains the proceedings of the 16th International Taurine Meeting consisting, of 54 original papers. This volume focuses on all aspects of taurine research, including topics of interest to today’sscientistsaswellasfutureclinicalapplications. PartI.CardiovascularandRenalEffectsofTaurine. PartII.EffectofTaurineonBrainandRetina. PartIII.EffectofTaurineonSkeletalMuscle. PartIV.GastroentericandHepaticEffectsofTaurine. PartV.EffectofTaurineonBone. PartVI.EffectofTaurineonDiabetesandObesity. PartVII.PotentialTherapeuticEffectsofTaurine. PartVII.TaurineasanAntioxidant;RoleinImmuneSystemandOtherTissues. PartIX.RegulationoftheTaurineTransporter. Future interest in taurine will undoubtedly be robust. However, considerable work remains to develop and uncover key new facts regarding taurine. This book should provide insight into new avenues of investigation and help propel the field intotheneweraoftaurineresearch.Finally,theorganizerswishtothankallofthe participantsfortheirstimulatingdiscussions,probingquestionsandwrittencontri- butionsthatmadetheShimodataurinemeetinganunmitigatedsuccess. Wearedeeplythankfultoallscientistswhohaveaninterestintaurine,andare lookingforwardtoseeingthetaurinefamilyatthenextTaurinemeetinginFlorida. Alonewecandosolittle;togetherwecandosomuch. HelenKeller Osaka,Japan JunichiAzuma,MD USA StephenW.Schaffer,PhD Osaka,Japan TakashiIto,PhD Meeting Participants Dr.SatoshiAbe Dr.UdomChantharaksri TaishoPharmaceuticalCo.Ltd. MahidolUniversity JAPAN THAILAND [email protected] [email protected] Dr.ChangSoonAhn Dr.RussellW.Chesney AnsanCollege UniversityofTennessee KOREA USA [email protected] [email protected] Mr.TakaoAketo Dr.MiJaChoi TaishoPharmaceuticalCo.Ltd. KeimyungUniversity JAPAN KOREA [email protected] [email protected] Dr.MedeyaAkhalaya Dr.FiliFazzino M.V.LomonosovMoscowState InstitutoVenezolanodeInvestigaciones University Cient´ıficas RUSSIA VENESUELA [email protected] [email protected] Dr.JunichiAzuma Mr.JunichiFukutome OsakaUniversity TaishoPharmaceuticalCo.Ltd JAPAN JAPAN [email protected] [email protected] Dr.KyungJaChang Dr.ShoichiroHamano InhaUniversity HamanoInternationalCo.,Ltd. KOREA JAPAN [email protected] [email protected] vii viii MeetingParticipants Dr.XiaobinHan Dr.KyoungSooKim UniversityofTennessee KyungHeeUniversity USA KOREA [email protected] [email protected] Dr.TakuzoHano Dr.AnKeunKim WakayamaMedicalUniversity SookmyungWomen’sUniversity JAPAN KOREA [email protected] [email protected] Dr.AbdeslemElIdrissi Dr.ChaekyunKim CityUniversityofNewYork InhaUniversitySchoolofMedicine USA KOREA [email protected] [email protected] Dr.KenichiImagawa Dr.YoungChulKim PharmacogenomeTipTopInc. SeoulNationalUniversity JAPAN KOREA [email protected] [email protected] Dr.TakashiIto Dr.MasayoshiKuwahara OsakaUniversity TheUniversityofTokyo JAPAN JAPAN [email protected] [email protected] Dr.JangmiKang Dr.CesarLau-Cam HyogoNCCcollege St.John’sUniversity JAPAN USA [email protected] [email protected] Dr.YoungSookKang Dr.Dong-HeeLee SookmyungWomen’sUniversity UniversityofSeoul KOREA KOREA [email protected] [email protected] Dr.ByongKakKim Dr.YuTehLi SeoulNationalUniversity TulaneUniversitySchoolofMedicine KOREA USA [email protected] [email protected] Dr.HaWonKim Dr.NingMa UniversityofSeoul UniversityofTokushima KOREA JAPAN [email protected] [email protected] MeetingParticipants ix Dr.JanuszMarcinkiewicz Mr.HaruakiNobori MedicalCollegeJagiellonianUniversity OsakaUniversity POLAND JAPAN [email protected] [email protected] Dr.TadaomiAMiyamoto Dr.ConnyNordin KokuraMemorialHospital LincopingUniversity JAPAN SWEDEN [email protected] [email protected] Dr.TeruoMiyazaki Dr.SoniaNusetti GeorgeWashingtonUniversity UniversidaddeOrienteCumana USA VENESUELA [email protected] [email protected] Dr.MariMori Dr.TetsuyaOgino MukogawaWomen’sUniversity OkayamaUniversity JAPAN JAPAN [email protected] [email protected] Dr.ShigeruMurakami Dr.SimoS.Oja TaishoPharmaceuticalCo.Ltd. UniversityofTampere JAPAN FINLAND [email protected] simo.oja@uta.fi Dr.JunichiNakagawa Mr.YudhachaiRajatasereekul TokyoUniversityofAgriculture OsotspaCoLtd JAPAN THAILAND [email protected] [email protected] Dr.SeiichiroNishida Dr.SanyaRoysommuti NaraMedicalUniversity KhonKaenUniversity JAPAN THAILAND s [email protected] [email protected] Dr.HidekiNishimura Dr.MartinSamuelsson TokyoWomensMedicalUniversity LincopingUniversity JAPAN SWEDEN [email protected] [email protected] Dr.NaomichiNishimura Dr.ChaichanSangdee NayoroCityUniversity ChaingMaiUniversity JAPAN THAILAND [email protected] [email protected] x MeetingParticipants Dr.PirjoSaransaari Ms.MikaTakai UniversityofTampere OsakaUniversity FINLAND JAPAN pirjo.saransaari@uta.fi [email protected] Dr.HemantaK.Sarkar Ms.AtcharapornThaeomor BBTech KhonKaenUniversity USA THAILAND [email protected] [email protected] Mr.NoppadolTunglukmongkol Dr.HiroyasuSatoh OsotspaCoLtd NaraMedicalUniversity THAILAND JAPAN [email protected] [email protected] Mr.ShuichiUmeda Dr.StephenW.Schaffer TaishoPharmaceuticalCo.Ltd UniversityofSouthAlabama JAPAN USA [email protected] [email protected] Ms.YorikoUozumi Dr.YukioSeki TaishoPharmaceuticalCo.Ltd ChubuRosaiHospital JAPAN JAPAN [email protected] [email protected] Ms.GaofengWu Dr.MakotoShimizu ShenYangAgriculturalUniversity TheUniversityofTokyo CHINA JAPAN [email protected] [email protected] Dr.JangYenWu Dr.KyokoTakahashi FloridaAtlanticUniversity OsakaUniversity USA JAPAN [email protected] [email protected] Dr.YukioYamori Mr.ToshioTakahashi InternationalCenterforResearchon TaishoPharmaceuticalCo.Ltd PrimaryPreventionofCardiovascular JAPAN DiseasesWHOExpertAdvisoryPanel [email protected] JAPAN [email protected] Dr.MasaruTakahashi TaishoPharmaceuticalCo.Ltd Dr.YoshihisaYatabe JAPAN MoriyaDaiichiHospital [email protected] JAPAN [email protected]
Description:The list of books you might like
