RESE ARCH b e y o n Tar geted researc h in depres sion, anxiety an d related disor ders d b lu 2007-2010 e : t h e n a t io n a l d e p r e s s io n in it ia t iv e R e s e a r c h 2 0 0 7 - 2 0 1 0 T a r g e t e d r e s e a r c h in d e p r e s s io n , a n x ie t y a n d r e la t e d d is o r d e r s 1300 22 4636 About beyondblue: the national depression initiative beyondblue is a national, independent, not-for-profit organisation working to address issues associated with depression, anxiety and related disorders in Australia. beyondblue is a bipartisan initiative of the Australian national, state and territory governments with a key goal of raising community awareness of depression and anxiety, and reducing the stigma associated with these illnesses. Our mission is to provide a national focus and community leadership to increase awareness within the Australian community, promote evidence-based strategies for the prevention of depression and anxiety, and increase access to effective interventions. We aim to build a society that understands and responds to the personal and social impact of depression and anxiety, works actively to prevent the illnesses, and improves the quality of life for everyone affected. beyondblue acknowledges Aboriginal and Torres Strait Islander peoples as the traditional owners of this land and the Elders past and present throughout Australia. We particularly acknowledge the Wurundjeri people of the Kulin nation, the traditional owners of the land where the beyondblue office is located. Research 2007-2010 Targeted research in depression, anxiety and related disorders beyondblue: the national depression initiative ISBN 978-1-921821-04-2 beyondblue: the national depression initiative Info line 1300 22 4636 or [email protected] www.beyondblue.org.au © Copyright Beyond Blue Ltd This publication can be downloaded from www.beyondblue.org.au The purpose of this publication is to summarise research projects which have been funded by Beyond Blue Limited (beyondblue). Research information and terminology has been provided by the investigators and not beyondblue. beyondblue makes no warranty about the accuracy of the summaries and recommends that anyone seeking to rely on information contained in the summaries should review the relevant project report in full (available at www.beyondblue.org.au or by emailing [email protected]), or seek further details from the chief investigator. While every care has been taken in preparing this publication, beyondblue does not, to the extent permitted by law, accept any liability for any injury, loss or damage suffered by any person arising from the use of, or reliance upon, the content of this publication. Contents Foreword ................................................................................................................... iv Introduction ................................................................................................................ v Section 1: Completed research project summaries .................................................. 1 List of completed research summaries ......................................................................2 Section 2: In-progress research projects ...............................................................125 List of in-progress research summaries .................................................................126 Investigator index ...................................................................................................167 Foreword In the ten years since 2000, when beyondblue was founded, we have not only committed to raising awareness of depression and anxiety, and reducing the associated stigma, but we have made it a priority to invest in high quality research. beyondblue has allocated more than $50 million across 207 research projects between 2001 and 2010. This research book builds on the first edition, Research 2001- 2007, to bring together summaries of all beyondblue’s completed research projects from 2007 to 2010. It highlights the diverse range of beyondblue-funded research projects that target specific areas of mental health and includes an overview of the projects currently underway. Our commitment to address gaps in depression-related research stems from a need to improve our understanding of depression, anxiety and related disorders, particularly on the frontline – to assist GPs and people who work in community health services, where the majority of people with depression and/or anxiety are first diagnosed and treated. It is our hope that beyondblue-funded research will help Australia’s health professionals to deliver world class and appropriate care. One of the most gratifying aspects of my role at beyondblue is seeing the results of beyondblue-funded research translated into practical, early intervention programs to help people with depression, anxiety or a related disorder – and their families – to get the help they need and to get their lives back on track. Two examples of research leading to community programs are our Perinatal Program and KidsMatter Programs that are being rolled out across the nation. I would like to extend my sincere thanks to the Federal, State and Territory Governments who have committed funding to beyondblue to enable us to carry out this research – and to our many corporate and community partners – and individuals – who have also made generous donations. I am extremely proud of the rich body of research beyondblue has funded and I look forward to future research findings being incorporated into policy and practice – which will benefit the many thousands of Australians who experience depression and anxiety, and their families. The Hon. Jeff Kennett AC Chairman beyondblue: the national depression initiative page iv Introduction I am pleased to present beyondblue’s Research: Targeted research in depression, anxiety and related disorders 2007-2010, which follows on from Research 2001-2007, published in 2008.1 Research 2007-2010 includes a synopsis of 62 projects completed during this period. The book consists of two sections: Section 1, Chapters 1 to 19, represents key topic areas, while Section 2 provides a compilation of all current and ongoing beyondblue-funded research projects. In keeping with beyondblue’s intent to foster Our collaborative and multidisciplinary collaborative and diverse research, projects approach to research is fostered through are often applicable to more than one topic partnerships with the National Heart area. To assist with locating reports, the start Foundation and Cancer Australia; under of each chapter lists projects relating to that beyondblue’s Strategic Research Grants; topic and where each report can be found and through the beyondblue Victorian Centre within this book. of Excellence in Depression, Anxiety and Since 2001, beyondblue has disseminated Related Disorders (bbVCoE). over $50 million in research funding across Established in 2002, the bbVCoE is a more than 200 projects and a range of collaborative venture between beyondblue research topics, including young people, and the Victorian Government. The bbVCoE chronic illness and older people (Figure 1, is an annual Victorian research grant program page vi). that encourages innovative, high-quality The breadth of research themes, with research to enhance the evidence for early a central focus on people with the intervention, treatment and pathways to illnesses, has helped to bridge gaps in quality care for depression, anxiety and knowledge across the lifespan, in a range related disorders. Since 2002, the bbVCoE of settings, including community, primary has allocated more than $12.5 million care, workplace and schools. Projects towards 114 research projects. Many of have rigorously assessed the efficacy of these research projects have been successful interventions (relapse prevention, early in stimulating the development of practice intervention, treatment) for each of these guidelines, numerous resources, tools and themes across the spectrum of depression programs – including the National Perinatal and anxiety severity. Depression Initiative – which have had a Depression and anxiety often co-occur with significant impact on mental health policy, other illnesses and can affect people from all fostered academic endeavour, increased cultural backgrounds and life circumstances. mental health literacy and access to services. beyondblue research efforts continue to The beyondblue and National Heart build partnerships with other organisations Foundation Strategic Research Program has to fund integrated research investigating the disseminated over $1.6 million to improve the psychosocial impact of chronic illness. understanding of the impact of depression and anxiety for people with cardiovascular 1. beyondblue: the national depression initiative. 2008. disease and their carers. The partnership Research: Targeted research in depression, anxiety has resulted in better access to support and related disorders 2001-2007. beyondblue, for people experiencing heart disease and Melbourne, Australia. page v Aboriginal and Torres Strait Islander people (5%) Bipolar disorder (3%) Carers and community (3%) Children and young people (13%) Chronic illness (23%) Culturally and linguistically diverse (3%) Disability (4%) Domestic violence (1%) Eating disorders/obesity (2%) e-mental health (4%) Employment and workforce (5%) Gay, lesbian, bisexual, transgender and intersex (2%) Men (1%) Miscellaneous (1%) Older people (8%) Outdoors and nature (1%) Perinatal mental health (2%) Primary care (8%) Rural (2%) Substance use and addictions (6%) Trauma/disaster recovery (1%) Women (1%) Distribution of grants (%) Figure 1: Diversity of beyondblue-funded projects 2001-2010 (percentage of projects by topic). Many research projects apply to more than one topic however the topic of most relevance is chosen for classification purposes. depression. The Priority-driven Collaborative Projects and Communications Teams who Cancer Research Scheme, a partnership work tirelessly to support our research between beyondblue and Cancer Australia, has programs and widely promote the results. distributed over $2.6 million for research focusing As I reflect on the research outcomes and the on the psychosocial impacts of depression on significant improvements in knowledge and in patients with cancer and their families. practice, I’m confident we are making great In addition to funding applied research that progress in reforming attitudes and systems. is priority-driven, evidence based and fosters Together with our research collaborators and collaborations, beyondblue aims to maintain supporters we are delivering on our mission high standards of excellence during its and will continue to reduce the impact of funding selection process. All beyondblue depression and anxiety and increase access funding applications are subject to rigorous to effective interventions Australia-wide. peer-review by a panel of academic researchers, consumers and clinicians. I would like to acknowledge and thank the beyondblue Chairman and Board, Expert Working Groups and the Clinical Research Committee, particularly Professors Bruce Singh and David Clarke, whose advice and Leonie Young guidance underpin the quality of our research Chief Executive Officer activities, and to the beyondblue Research beyondblue: the national depression initiative page vi Section 1: Completed research project summaries This section contains summaries of beyondblue-funded research projects completed between 2007 and 2010. Completed research project summaries Chapter 1: Aboriginal and Torres Strait Islander people Development of depression first aid standards for Indigenous Australians ........................................ 8 Development of alcohol misuse first aid guidelines for Indigenous Australians .................................. 9 Development of drug misuse first aid guidelines for Aboriginal and Torres Strait Islander people ..... 10 Mibbinbah: Indigenous men’s sheds/spaces pilot project ............................................................... 11 Evaluation of Indigenous Hip Hop Projects ..................................................................................... 12 Chapter 2: Bipolar disorder Automated longitudinal monitoring to predict and counter relapse in bipolar disorder: a pilot investigation of effectiveness .......................................................................................................... 16 Chapter 3: Children and young people Time for a future: effective treatment of depressed youth in urban and rural primary care settings ................................................................................................................................... 19 A three to eight-year follow-up of adolescents treated for depression and their families: predictors of treatment outcome .................................................................................................... 20 Effective management of school refusal and childhood anxiety as a community-based early intervention to prevent subsequent depression: a randomised comparative treatment study .......... 21 KidsMatter primary evaluation ......................................................................................................... 22 Improving the engagement, detection and management of adolescent depression: applying the mobiletype program to general practice settings ............................................................................. 24 Investigating the interaction between depression, tobacco and alcohol use in teenage Australians – can we identify a high risk group for poor outcome? A longitudinal study ................... 25 Looking beyond dual diagnosis: young people speak out ............................................................... 27 What works for the treatment of depression in young people .......................................................... 28 Chapter 4: Chronic illness A pragmatic trial of a stepped care intervention for people with depression and cardiac failure ....... 30 Depression as a predictor of long-term mortality after heart attack ................................................. 31 A nurse-assisted screening and referral program for depression among survivors of cancer: a pilot study .................................................................................................................................... 33 Type 1 diabetes as a risk factor for depression and other adverse outcomes in adolescents and young adults from rural Victoria ................................................................................................ 34 Screening and management of depression in cardiac settings: an examination of clinical practice and a national study of prevalence of screening for depression by cardiologists and their beliefs regarding screening and management ......................................................................... 36 Improving depression and anxiety screening of patients with heart disease: implementing a multidisciplinary clinical pathway ..................................................................................................... 39 Recognition of depression in patients with chronic obstructive pulmonary disease in Victoria.......... 41 page 2
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